AU2003302463A1 - Methods for analyzing a nucleic acid - Google Patents

Methods for analyzing a nucleic acid

Info

Publication number
AU2003302463A1
AU2003302463A1 AU2003302463A AU2003302463A AU2003302463A1 AU 2003302463 A1 AU2003302463 A1 AU 2003302463A1 AU 2003302463 A AU2003302463 A AU 2003302463A AU 2003302463 A AU2003302463 A AU 2003302463A AU 2003302463 A1 AU2003302463 A1 AU 2003302463A1
Authority
AU
Australia
Prior art keywords
analyzing
methods
nucleic acid
nucleic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003302463A
Other languages
English (en)
Other versions
AU2003302463A8 (en
Inventor
Eugene Y. Chan
Eric Nalefski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Genomics Inc
Original Assignee
US Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Genomics Inc filed Critical US Genomics Inc
Publication of AU2003302463A1 publication Critical patent/AU2003302463A1/en
Publication of AU2003302463A8 publication Critical patent/AU2003302463A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003302463A 2002-05-09 2003-05-09 Methods for analyzing a nucleic acid Abandoned AU2003302463A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37946102P 2002-05-09 2002-05-09
US60/379,461 2002-05-09
PCT/US2003/014776 WO2004048514A2 (en) 2002-05-09 2003-05-09 Methods for analyzing a nucleic acid

Publications (2)

Publication Number Publication Date
AU2003302463A1 true AU2003302463A1 (en) 2004-06-18
AU2003302463A8 AU2003302463A8 (en) 2004-06-18

Family

ID=32393218

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003302463A Abandoned AU2003302463A1 (en) 2002-05-09 2003-05-09 Methods for analyzing a nucleic acid

Country Status (5)

Country Link
US (1) US20030235854A1 (US20060057565A1-20060316-C00011.png)
EP (1) EP1540017A4 (US20060057565A1-20060316-C00011.png)
JP (1) JP2005537030A (US20060057565A1-20060316-C00011.png)
AU (1) AU2003302463A1 (US20060057565A1-20060316-C00011.png)
WO (1) WO2004048514A2 (US20060057565A1-20060316-C00011.png)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE273381T1 (de) 1997-02-12 2004-08-15 Eugene Y Chan Verfahren zur analyse von polymeren
US6696022B1 (en) 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US6927065B2 (en) 1999-08-13 2005-08-09 U.S. Genomics, Inc. Methods and apparatus for characterization of single polymers
EP1354064A2 (en) 2000-12-01 2003-10-22 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
WO2002101095A1 (en) * 2001-06-08 2002-12-19 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids using nick translation
WO2003100101A1 (en) * 2002-05-28 2003-12-04 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
US7282330B2 (en) 2002-05-28 2007-10-16 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
JP2007501003A (ja) * 2003-08-01 2007-01-25 ユー．エス． ジェノミクス， インコーポレイテッド 非切断条件下で核酸を分析するための配列特異的エンドヌクレアーゼの使用に関連した方法および組成物
WO2005017205A2 (en) * 2003-08-04 2005-02-24 U. S. Genomics, Inc. Nucleic acid mapping using linear analysis
WO2005022162A1 (en) * 2003-08-21 2005-03-10 U.S. Genomics, Inc. Quantum dots and methods of use thereof
WO2005047470A2 (en) * 2003-11-07 2005-05-26 U.S. Genomics, Inc. Intercalator fret donors or acceptors
US7595160B2 (en) 2004-01-13 2009-09-29 U.S. Genomics, Inc. Analyte detection using barcoded polymers
US7977048B2 (en) 2004-01-13 2011-07-12 Pathogenetix, Inc. Detection and quantification of analytes in solution using polymers
US7575863B2 (en) * 2004-05-28 2009-08-18 Applied Biosystems, Llc Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
WO2006017274A2 (en) * 2004-07-13 2006-02-16 U.S. Genomics, Inc. Systems and methods for sample modification using fluidic chambers
US7351538B2 (en) 2004-08-23 2008-04-01 U.S. Genomics Systems and methods for detecting and analyzing polymers
EP2186908A1 (en) * 2004-09-21 2010-05-19 Applied Biosystems, LLC Two-color real-time/end-point quantitation of microRNAs (miRNAs)
WO2006098772A2 (en) * 2004-10-13 2006-09-21 U.S. Genomics, Inc. Systems and methods for measurement optimization
US7888011B2 (en) * 2004-10-18 2011-02-15 U.S. Genomics, Inc. Methods for isolation of nucleic acids from prokaryotic spores
WO2007011660A2 (en) * 2005-07-14 2007-01-25 William Marsh Rice University Quantum dot probes
US20070128083A1 (en) * 2005-07-18 2007-06-07 U.S. Genomics, Inc. Microfluidic methods and apparatuses for sample preparation and analysis
JP4767654B2 (ja) * 2005-10-21 2011-09-07 株式会社エヌ・ティ・ティ・ドコモ 分子伝送・分子配送システムおよび分子伝送・分子配送方法
US20080241071A1 (en) * 2006-07-14 2008-10-02 West Jennifer L Quantum Dot Probes
SG173398A1 (en) 2006-07-19 2011-08-29 Bionanomatrix Inc Nanonozzle device arrays: their preparation and use for macromolecular analysis
CN101680864A (zh) * 2006-09-18 2010-03-24 应用生物系统有限责任公司 用于聚光机制的方法、系统和装置
US8999636B2 (en) 2007-01-08 2015-04-07 Toxic Report Llc Reaction chamber
AU2008232616B2 (en) * 2007-03-28 2014-08-07 Bionano Genomics, Inc. Methods of macromolecular analysis using nanochannel arrays
JP5730762B2 (ja) 2008-06-30 2015-06-10 バイオナノ ジェノミックス、インク． 単一分子全ゲノム解析のための方法及び装置
US8361716B2 (en) 2008-10-03 2013-01-29 Pathogenetix, Inc. Focusing chamber
CN102292454B (zh) 2008-11-18 2014-11-26 博纳基因技术有限公司 多核苷酸作图和测序
WO2010091023A2 (en) * 2009-02-03 2010-08-12 Complete Genomics, Inc. Indexing a reference sequence for oligomer sequence mapping
US8615365B2 (en) * 2009-02-03 2013-12-24 Complete Genomics, Inc. Oligomer sequences mapping
EP2394165A4 (en) * 2009-02-03 2013-12-11 Complete Genomics Inc ASSIGNMENT OF OLIGOMER SEQUENCES
JP5661251B2 (ja) * 2009-03-31 2015-01-28 積水メディカル株式会社 Ｕｇｔ１ａ１遺伝子多型検出法
DK2511843T3 (en) * 2009-04-29 2017-03-27 Complete Genomics Inc METHOD AND SYSTEM FOR DETERMINING VARIATIONS IN A SAMPLE POLYNUCLEOTIDE SEQUENCE IN TERMS OF A REFERENCE POLYNUCLEOTIDE SEQUENCE
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US8956815B2 (en) 2012-04-18 2015-02-17 Toxic Report Llc Intercalation methods and devices
US8685708B2 (en) 2012-04-18 2014-04-01 Pathogenetix, Inc. Device for preparing a sample
US9028776B2 (en) 2012-04-18 2015-05-12 Toxic Report Llc Device for stretching a polymer in a fluid sample
CN105849275B (zh) 2013-06-25 2020-03-17 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
US10726942B2 (en) 2013-08-23 2020-07-28 Complete Genomics, Inc. Long fragment de novo assembly using short reads
EP3530752B1 (en) 2015-04-10 2021-03-24 Spatial Transcriptomics AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
EP3894585A2 (en) 2018-12-10 2021-10-20 10X Genomics, Inc. Generating capture probes for spatial analysis
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
CN109922430B (zh) * 2019-03-20 2020-12-18 苏州真趣信息科技有限公司 受限空间作业系统及方法
EP3976820A1 (en) 2019-05-30 2022-04-06 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
EP4025711A2 (en) 2019-11-08 2022-07-13 10X Genomics, Inc. Enhancing specificity of analyte binding
SG11202106899SA (en) 2019-12-23 2021-09-29 10X Genomics Inc Methods for spatial analysis using rna-templated ligation
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
EP4242325A3 (en) 2020-04-22 2023-10-04 10X Genomics, Inc. Methods for spatial analysis using targeted rna depletion
EP4153775A1 (en) 2020-05-22 2023-03-29 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
EP4153776A1 (en) 2020-05-22 2023-03-29 10X Genomics, Inc. Spatial analysis to detect sequence variants
WO2021252499A1 (en) 2020-06-08 2021-12-16 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
AU2021294334A1 (en) 2020-06-25 2023-02-02 10X Genomics, Inc. Spatial analysis of DNA methylation
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
AU2021409136A1 (en) 2020-12-21 2023-06-29 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
WO2023034489A1 (en) 2021-09-01 2023-03-09 10X Genomics, Inc. Methods, compositions, and kits for blocking a capture probe on a spatial array

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US6007987A (en) * 1993-08-23 1999-12-28 The Trustees Of Boston University Positional sequencing by hybridization
FR2716263B1 (fr) * 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
ATE273381T1 (de) * 1997-02-12 2004-08-15 Eugene Y Chan Verfahren zur analyse von polymeren
US6403311B1 (en) * 1997-02-12 2002-06-11 Us Genomics Methods of analyzing polymers using ordered label strategies
US6210896B1 (en) * 1998-08-13 2001-04-03 Us Genomics Molecular motors
US6322980B1 (en) * 1999-04-30 2001-11-27 Aclara Biosciences, Inc. Single nucleotide detection using degradation of a fluorescent sequence
US6927065B2 (en) * 1999-08-13 2005-08-09 U.S. Genomics, Inc. Methods and apparatus for characterization of single polymers
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
EP1265709A2 (en) * 2000-03-17 2002-12-18 Aclara BioSciences, Inc. Microfluidic device and system with additional peripheral channels
US20060008799A1 (en) * 2000-05-22 2006-01-12 Hong Cai Rapid haplotyping by single molecule detection
WO2002101353A2 (en) * 2001-06-08 2002-12-19 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids based on methylation status
WO2002101095A1 (en) * 2001-06-08 2002-12-19 U.S. Genomics, Inc. Methods and products for analyzing nucleic acids using nick translation
US8423294B2 (en) * 2001-09-18 2013-04-16 Pathogenetix, Inc. High resolution linear analysis of polymers
EP1436424A4 (en) * 2001-09-18 2005-11-16 Us Genomics Inc DIFFERENTIAL MARKING OF POLYMERS FOR HIGH RESOLUTION LINEAR ANALYSIS
AU2003228649A1 (en) * 2002-04-23 2003-11-10 U.S.Genomics, Inc. Compositions and methods related to two-arm nucleic acid probes
WO2003100101A1 (en) * 2002-05-28 2003-12-04 U.S. Genomics, Inc. Methods and apparati using single polymer analysis
EP1543155A4 (en) * 2002-07-17 2006-08-16 Us Genomics Inc METHODS AND COMPOSITIONS FOR ANALYZING POLYMERS USING CHIMERIC MARKERS
EP1586068B1 (en) * 2003-01-23 2008-07-30 U.S. Genomics, Inc. Methods for analyzing polymer populations
JP2007501003A (ja) * 2003-08-01 2007-01-25 ユー．エス． ジェノミクス， インコーポレイテッド 非切断条件下で核酸を分析するための配列特異的エンドヌクレアーゼの使用に関連した方法および組成物
WO2005022162A1 (en) * 2003-08-21 2005-03-10 U.S. Genomics, Inc. Quantum dots and methods of use thereof
WO2005047470A2 (en) * 2003-11-07 2005-05-26 U.S. Genomics, Inc. Intercalator fret donors or acceptors
US7977048B2 (en) * 2004-01-13 2011-07-12 Pathogenetix, Inc. Detection and quantification of analytes in solution using polymers

Also Published As

Publication number Publication date
EP1540017A4 (en) 2006-05-24
WO2004048514A2 (en) 2004-06-10
JP2005537030A (ja) 2005-12-08
EP1540017A2 (en) 2005-06-15
US20030235854A1 (en) 2003-12-25
WO2004048514A3 (en) 2005-04-21
AU2003302463A8 (en) 2004-06-18

Similar Documents

Publication Publication Date Title
AU2003302463A1 (en) Methods for analyzing a nucleic acid
AU2002304705A1 (en) Method for analysing nucleic acid chains
AU2003299541A1 (en) Microfluidic nucleic acid analysis
AU2002332940A1 (en) Device for analyzing nucleic acid
AU2003208489A1 (en) Method for desinging a well completion
AUPS298102A0 (en) Method for performing chemical reactions
AU2003237306A1 (en) A method of using data binning in the analysis of chromatograhpy/spectrometry data
AU2003256537A1 (en) Nucleic acid labeling methods
AU2003268457A1 (en) Biomap analysis
AU2003277509A1 (en) Analytical tool
AU2003232086A1 (en) Nucleic acid-associated proteins
AU2003230070A1 (en) Isolating nucleic acid
AU2003303869A1 (en) Methods for nucleic acid analysis
AU2003250710A1 (en) Sampling method
AU2003901196A0 (en) Analysis method
AU2003217992A1 (en) Nucleic acid-associated proteins
AU2003266637A1 (en) Analyzing tool
AU2003275856A1 (en) Method for detecting halitosis
AU2003234171A1 (en) Method for evaluating drug candidates
AU2003302685A1 (en) Methylation dna detecting method
AU2003224265A1 (en) Nucleic acid immunization
AU2003263714A1 (en) Method for obtaining a fraction
AU2003219396A1 (en) Isolating nucleic acid
AU2003212358A1 (en) Method for identifying a nucleic acid analyte
AU2001271255A1 (en) Method for analyzing a nucleic acid

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase