AU2003299196A1 - Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines - Google Patents

Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines Download PDF

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Publication number
AU2003299196A1
AU2003299196A1 AU2003299196A AU2003299196A AU2003299196A1 AU 2003299196 A1 AU2003299196 A1 AU 2003299196A1 AU 2003299196 A AU2003299196 A AU 2003299196A AU 2003299196 A AU2003299196 A AU 2003299196A AU 2003299196 A1 AU2003299196 A1 AU 2003299196A1
Authority
AU
Australia
Prior art keywords
ssri
composition
patient
peg
corticosteroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003299196A
Other languages
English (en)
Inventor
Benjamin A. Auspitz
Bradley B. Brasher
Todd W. Chappell
Jason Fong
Daniel Grau
Edward Roydon Jost-Price
Curtis Keith
Palaniyandi Manivasakam
M. James Nichols
Noah Sachs
Brendan Smith
Grant R. Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zalicus Inc
Original Assignee
CombinatoRx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32074779&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2003299196(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CombinatoRx Inc filed Critical CombinatoRx Inc
Publication of AU2003299196A1 publication Critical patent/AU2003299196A1/en
Assigned to COMBINATORX, INCORPORATED reassignment COMBINATORX, INCORPORATED Request for Assignment Assignors: AUSPITZ, BENJAMIN, Brasher, Bradley, Chappell, Todd, COMBINATORX, INCORPORATED, FONG, JASON, KEITH, CURTIS, MANIVASAKAM, PALANIYANDI, NICHOLS, M. JAMES, SACHS, NOAH, SMITH, BRENDAN, ZIMMERMANN, GRANT
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2003299196A 2002-09-24 2003-09-24 Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines Abandoned AU2003299196A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US41304002P 2002-09-24 2002-09-24
US60/413,040 2002-09-24
US41726102P 2002-10-09 2002-10-09
US60/417,261 2002-10-09
US42752602P 2002-11-19 2002-11-19
US42742402P 2002-11-19 2002-11-19
US60/427,526 2002-11-19
US60/427,424 2002-11-19
US46475303P 2003-04-23 2003-04-23
US60/464,753 2003-04-23
PCT/US2003/030156 WO2004030618A2 (fr) 2002-09-24 2003-09-24 Methodes et reactifs destines au traitement de maladies et de troubles associes a des niveaux accrus de cytokines pro-inflammatoires

Publications (1)

Publication Number Publication Date
AU2003299196A1 true AU2003299196A1 (en) 2004-04-23

Family

ID=32074779

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003299196A Abandoned AU2003299196A1 (en) 2002-09-24 2003-09-24 Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines

Country Status (12)

Country Link
EP (1) EP1553955A4 (fr)
JP (1) JP2006503905A (fr)
AR (1) AR041386A1 (fr)
AU (1) AU2003299196A1 (fr)
BR (1) BR0314713A (fr)
CA (1) CA2509526A1 (fr)
HR (1) HRP20050355A2 (fr)
IS (1) IS7811A (fr)
MX (1) MXPA05003152A (fr)
NO (1) NO20051669L (fr)
TW (1) TW200422042A (fr)
WO (1) WO2004030618A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004212919A1 (en) * 2003-02-14 2004-09-02 Combinatorx, Incorporated Combination therapy for the treatment of immunoinflammatory disorders
CA2538023A1 (fr) * 2003-09-24 2005-04-07 Combinatorx, Incorporated Schemas posologiques therapeutiques pour une administration de combinaisons de medicaments
MXPA06013463A (es) * 2004-05-17 2007-03-01 Combinatorx Inc Metodos y reactivos para el tratamiento de desordenes inmuno-inflamatorios.
AU2011236053B2 (en) * 2004-11-19 2014-06-26 Merck Sharpe & Dohme B.V. Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CA2585317C (fr) * 2004-11-19 2015-02-24 N.V. Organon Association de medicaments pour le traitement de depressions et de troubles s'y rapportant, comprenant un inhibiteur selectif de la recapture dela serotonine depression
EP1719507B1 (fr) * 2005-04-13 2010-07-14 Astion Development A/S Des agonistes de bêta-2 adrénocepteur pour le traitement de maladies des tissus conjonctifs de la peau
JP4832806B2 (ja) * 2005-06-03 2011-12-07 久光製薬株式会社 経皮投与製剤
TW200711649A (en) * 2005-06-17 2007-04-01 Combinatorx Inc Combination therapy for the treatment of immunoinflammatory disorders
EP2059234B1 (fr) * 2006-09-08 2011-11-02 Ore Pharmaceuticals Inc. Procédé pour réduire ou soulager une inflammation dans le tube digestif
WO2008033754A2 (fr) * 2006-09-11 2008-03-20 Duke University Méthodes et compositions de traitement de la dépression vasculaire.
GB0701171D0 (en) * 2007-01-22 2007-02-28 Imp Innovations Ltd Compositions and uses thereof
WO2010098230A1 (fr) * 2009-02-27 2010-09-02 久光製薬株式会社 Préparation transdermique
PT117765A (pt) * 2022-01-28 2023-07-28 Faculdade De Farmacia Da Univ De Lisboa Formulação tópica de fluvoxamina para o tratamento de psoríase
WO2024074699A1 (fr) * 2022-10-07 2024-04-11 Oculis Operations Sarl Microsuspensions de gouttes oculaires d'inhibiteurs de mtor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007863A1 (fr) * 1991-10-15 1993-04-29 Mullarkey Michael F Procedes et compositions servant a traiter des reactions allergiques
GB9603137D0 (en) * 1996-02-15 1996-04-17 Merck Sharp & Dohme Therapeutic agents
ES2259746T3 (es) * 1996-07-15 2006-10-16 Alza Corporation Nuevas formulaciones para la administracion transdermica de fluoxetina.
CA2282845A1 (fr) * 1997-03-18 1998-09-24 Basf Aktiengesellschaft Procedes et compositions permettant de moduler la sensibilite aux corticosteroides
US6281248B1 (en) * 2000-02-16 2001-08-28 Magda Abdel Fattah Ahmed Composition for treating asthma
IL139975A0 (en) * 2000-11-29 2002-02-10 Univ Ramot Anti proliferative drugs

Also Published As

Publication number Publication date
HRP20050355A2 (en) 2005-10-31
WO2004030618A2 (fr) 2004-04-15
JP2006503905A (ja) 2006-02-02
MXPA05003152A (es) 2006-04-27
WO2004030618A3 (fr) 2005-04-07
BR0314713A (pt) 2005-07-26
EP1553955A4 (fr) 2008-11-05
AR041386A1 (es) 2005-05-18
NO20051669L (no) 2005-06-10
IS7811A (is) 2005-04-19
CA2509526A1 (fr) 2004-04-15
EP1553955A2 (fr) 2005-07-20
TW200422042A (en) 2004-11-01

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: ADD CO-INVENTOR GRAU, DANIEL

PC1 Assignment before grant (sect. 113)

Owner name: COMBINATORX, INCORPORATED

Free format text: FORMER APPLICANT(S): COMBINATORX, INCORPORATED; MANIVASAKAM, PALANIYANDI; SMITH, BRENDAN; FONG, JASON; AUSPITZ, BENJAMIN; NICHOLS, M. JAMES; KEITH, CURTIS; ZIMMERMANN, GRANT; BRASHER, BRADLEY; SACHS, NOAH; CHAPPELL, TODD

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application