AU2003288094A8 - Method for the selection of cells producing specifically binding molecules - Google Patents

Method for the selection of cells producing specifically binding molecules

Info

Publication number
AU2003288094A8
AU2003288094A8 AU2003288094A AU2003288094A AU2003288094A8 AU 2003288094 A8 AU2003288094 A8 AU 2003288094A8 AU 2003288094 A AU2003288094 A AU 2003288094A AU 2003288094 A AU2003288094 A AU 2003288094A AU 2003288094 A8 AU2003288094 A8 AU 2003288094A8
Authority
AU
Australia
Prior art keywords
cells
selection
specifically binding
binding molecules
cells producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003288094A
Other versions
AU2003288094A1 (en
Inventor
Burkhard Micheel
Frank Sellrie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Postdam
Original Assignee
Universitaet Postdam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Postdam filed Critical Universitaet Postdam
Publication of AU2003288094A1 publication Critical patent/AU2003288094A1/en
Publication of AU2003288094A8 publication Critical patent/AU2003288094A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a method for selecting cells expressing specifically binding molecules. Said method can be applied to all cells that are able to express specifically binding molecules, e.g. bacterial cells, yeast cells, fungal cells, insect cells, algae cells, plant cells, and mammal cells, and particularly hybridoma cells and stem cells, such as non-human embryonic stem cells. Moreover, the inventive method allows the selection to be made in a simple manner, the cells being provided in the form of an organ and/or tissue. The selection can be made in vitro or in vivo. Nucleic acids, polysaccharides, proteins, or peptides, and especially antibodies and antibody fragments can be selected as molecules that are to be expressed.
AU2003288094A 2002-11-30 2003-11-17 Method for the selection of cells producing specifically binding molecules Abandoned AU2003288094A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10256042.0 2002-11-30
DE10256042A DE10256042B4 (en) 2002-11-30 2002-11-30 Method of selecting cells that produce specific binding molecules
PCT/EP2003/012863 WO2004050901A2 (en) 2002-11-30 2003-11-17 Method for the selection of cells producing specifically binding molecules

Publications (2)

Publication Number Publication Date
AU2003288094A1 AU2003288094A1 (en) 2004-06-23
AU2003288094A8 true AU2003288094A8 (en) 2004-06-23

Family

ID=32318852

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003288094A Abandoned AU2003288094A1 (en) 2002-11-30 2003-11-17 Method for the selection of cells producing specifically binding molecules

Country Status (5)

Country Link
EP (1) EP1565567B1 (en)
AT (1) ATE458825T1 (en)
AU (1) AU2003288094A1 (en)
DE (2) DE10256042B4 (en)
WO (1) WO2004050901A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI588259B (en) * 2015-03-06 2017-06-21 Methods for screening antigen-specific fusion tumor cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172110B1 (en) * 1988-04-15 1997-10-27 Gen Hospital Corp Method for Isolating Mutants of DNA Sequences and Their Use in Identifying Cell Surface Proteins
US5352595A (en) * 1991-09-03 1994-10-04 Fred Hutchinson Cancer Research Center Myod regulatory region
GB9200417D0 (en) * 1992-01-09 1992-02-26 Bagshawe Kenneth D Cytotoxic drug therapy
AU678179B2 (en) * 1992-07-28 1997-05-22 Steven Kessler Methods for positive immunoselection of stem cells
JPH09510201A (en) * 1994-03-07 1997-10-14 メダレツクス・インコーポレーテツド Bispecific molecules with clinical utility
EP0974649A1 (en) * 1998-06-22 2000-01-26 Universität Zürich Screening system
AU7493101A (en) * 2000-05-23 2001-12-03 Nexell Therapeutics Inc Reagents for cell selection and methods of use
DE10038573A1 (en) * 2000-08-03 2002-02-21 Mpb Cologne Gmbh Molecular Pla Procedure for selection on host cells with eliminated DNA sequences
DE10060959A1 (en) * 2000-12-06 2002-06-20 Aventis Res & Tech Gmbh & Co Processes for isolating and identifying effectors

Also Published As

Publication number Publication date
WO2004050901A2 (en) 2004-06-17
ATE458825T1 (en) 2010-03-15
AU2003288094A1 (en) 2004-06-23
EP1565567B1 (en) 2010-02-24
DE10256042A1 (en) 2004-06-17
WO2004050901A3 (en) 2004-08-12
DE50312455D1 (en) 2010-04-08
DE10256042B4 (en) 2006-06-08
EP1565567A2 (en) 2005-08-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase