AU2003283947A1 - Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids - Google Patents

Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Info

Publication number
AU2003283947A1
AU2003283947A1 AU2003283947A AU2003283947A AU2003283947A1 AU 2003283947 A1 AU2003283947 A1 AU 2003283947A1 AU 2003283947 A AU2003283947 A AU 2003283947A AU 2003283947 A AU2003283947 A AU 2003283947A AU 2003283947 A1 AU2003283947 A1 AU 2003283947A1
Authority
AU
Australia
Prior art keywords
mutants
deletion
amino acids
terminal amino
necrosis factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003283947A
Other versions
AU2003283947A8 (en
Inventor
Irena Fonda
Vladka Gaberc-Porekar
Maja Kenig
Viktor Menart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lek Pharmaceuticals dd
Original Assignee
Lek Pharmaceuticals dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals dd filed Critical Lek Pharmaceuticals dd
Publication of AU2003283947A1 publication Critical patent/AU2003283947A1/en
Publication of AU2003283947A8 publication Critical patent/AU2003283947A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003283947A 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids Abandoned AU2003283947A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SIP-200200279 2002-11-22
SI200200279A SI21373A (en) 2002-11-22 2002-11-22 Method of modulating biological activity of proteins
PCT/SI2003/000041 WO2004048409A2 (en) 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Publications (2)

Publication Number Publication Date
AU2003283947A1 true AU2003283947A1 (en) 2004-06-18
AU2003283947A8 AU2003283947A8 (en) 2004-06-18

Family

ID=32391126

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003283947A Abandoned AU2003283947A1 (en) 2002-11-22 2003-11-21 Mutants of the tumor necrosis factor alpha with deletion of n-terminal amino acids

Country Status (3)

Country Link
AU (1) AU2003283947A1 (en)
SI (1) SI21373A (en)
WO (1) WO2004048409A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1598075A1 (en) * 2004-05-21 2005-11-23 LEK Pharmaceuticals d.d. Process for the isolation and / or purification of proteins
TWI667253B (en) * 2016-12-30 2019-08-01 博晟生醫股份有限公司 Recombinant polypeptides and nucleic acid molecules, compositions, and methods of making and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677063A (en) * 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
DE69626829T2 (en) * 1995-08-04 2004-03-18 Lek Farmacevtska Druzba D.D. MONOCLONAL ANTIBODIES AGAINST SOLUBLE TNF-ALPHA RECEPTORS P55 AND P75 AND ALSO AGAINST TNF-ALPHA AND ITS ANALOGS

Also Published As

Publication number Publication date
AU2003283947A8 (en) 2004-06-18
WO2004048409A2 (en) 2004-06-10
SI21373A (en) 2004-06-30
WO2004048409A3 (en) 2004-09-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase