AU2003276488A1 - High purity ondansetron hydrochloride dihydrate and process for its synthesis - Google Patents

High purity ondansetron hydrochloride dihydrate and process for its synthesis

Info

Publication number
AU2003276488A1
AU2003276488A1 AU2003276488A AU2003276488A AU2003276488A1 AU 2003276488 A1 AU2003276488 A1 AU 2003276488A1 AU 2003276488 A AU2003276488 A AU 2003276488A AU 2003276488 A AU2003276488 A AU 2003276488A AU 2003276488 A1 AU2003276488 A1 AU 2003276488A1
Authority
AU
Australia
Prior art keywords
synthesis
high purity
hydrochloride dihydrate
ondansetron hydrochloride
ondansetron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003276488A
Inventor
Laszlo Czibula
Ida Deutschne Juhasz
Laszlo Dobay
Istvan Hegedus
Judit Nagyne Bagdy
Ruben Olah
Laszlo Terdy
Geza Toth
Tamasne Uberhardt
Eva Werkne Papp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of AU2003276488A1 publication Critical patent/AU2003276488A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
AU2003276488A 2002-10-17 2003-10-16 High purity ondansetron hydrochloride dihydrate and process for its synthesis Abandoned AU2003276488A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HUP0203547 2002-10-17
HU0203547A HU225885B1 (en) 2002-10-17 2002-10-17 Process for producing ondansetron hydrochlorid dihydrate of high purity
PCT/HU2003/000081 WO2004035567A1 (en) 2002-10-17 2003-10-16 High purity ondansetron hydrochloride dihydrate and process for its synthesis

Publications (1)

Publication Number Publication Date
AU2003276488A1 true AU2003276488A1 (en) 2004-05-04

Family

ID=89980861

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003276488A Abandoned AU2003276488A1 (en) 2002-10-17 2003-10-16 High purity ondansetron hydrochloride dihydrate and process for its synthesis

Country Status (3)

Country Link
AU (1) AU2003276488A1 (en)
HU (1) HU225885B1 (en)
WO (1) WO2004035567A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2565854A1 (en) 2004-05-07 2005-11-17 Taro Pharmaceutical Industries Ltd. Process for preparing ondansetron hydrochloride dihydrate having a defined particle size

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
ZA200305338B (en) * 2001-01-11 2004-07-12 Teva Pharma An improved process for preparing pure ondansetron hydrochloride dihydrate.

Also Published As

Publication number Publication date
HU225885B1 (en) 2007-11-28
HUP0203547A3 (en) 2004-10-28
HU0203547D0 (en) 2002-12-28
HUP0203547A2 (en) 2004-06-28
WO2004035567A1 (en) 2004-04-29

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase