AU2003271568A1 - Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases - Google Patents

Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases

Info

Publication number
AU2003271568A1
AU2003271568A1 AU2003271568A AU2003271568A AU2003271568A1 AU 2003271568 A1 AU2003271568 A1 AU 2003271568A1 AU 2003271568 A AU2003271568 A AU 2003271568A AU 2003271568 A AU2003271568 A AU 2003271568A AU 2003271568 A1 AU2003271568 A1 AU 2003271568A1
Authority
AU
Australia
Prior art keywords
diagnostic
binding protein
neurodegenerative diseases
therapeutic use
thyroid hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003271568A
Inventor
Johannes Pohlner
Heinz Von Der Kammer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evotec Neurosciences GmbH
Original Assignee
Evotec Neurosciences GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evotec Neurosciences GmbH filed Critical Evotec Neurosciences GmbH
Publication of AU2003271568A1 publication Critical patent/AU2003271568A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/072Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
AU2003271568A 2002-09-02 2003-08-28 Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases Abandoned AU2003271568A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02019557.4 2002-09-02
EP02019557 2002-09-02
US40724902P 2002-09-03 2002-09-03
US60/407,249 2002-09-03
PCT/EP2003/009536 WO2004020666A2 (en) 2002-09-02 2003-08-28 Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases

Publications (1)

Publication Number Publication Date
AU2003271568A1 true AU2003271568A1 (en) 2004-03-19

Family

ID=56290477

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003271568A Abandoned AU2003271568A1 (en) 2002-09-02 2003-08-28 Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases

Country Status (3)

Country Link
EP (1) EP1534856A2 (en)
AU (1) AU2003271568A1 (en)
WO (1) WO2004020666A2 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980281A (en) * 1988-02-10 1990-12-25 Housey Gerard M Method of screening for protein inhibitors and activators
WO2000067033A1 (en) * 1999-05-03 2000-11-09 Evotec Biosystems Ag Methods of diagnosing or treating alzheimer's disease
US20040053265A1 (en) * 2000-08-24 2004-03-18 Rainer Hipfel Diagnostic and therapeutic use of a caveolae-associated integral membrane protein for alzheimer's disease and related neurodegenerative disorders
AU2002212233A1 (en) * 2000-09-13 2002-03-26 Evotec Neurosciences Gmbh Diagnostic and therapeutic use of a phosphoprotein enriched in astrocytes for alzheimer's disease and related neurodegenerative disorders
WO2002057496A2 (en) * 2001-01-18 2002-07-25 Socratech L.L.C. Gene expression profiling of endothelium in alzheimer's disease

Also Published As

Publication number Publication date
WO2004020666A2 (en) 2004-03-11
WO2004020666A3 (en) 2004-09-02
EP1534856A2 (en) 2005-06-01

Similar Documents

Publication Publication Date Title
AU2003264256A1 (en) A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction
AU2003239531A1 (en) Protein cages for the delivery of medical imaging and therapy
IL214262A0 (en) Therapeutic human anti-il-1r1 monoclonal antibody
AU2002952993A0 (en) Therapeutic and diagnostic agents
AU2003267532A1 (en) PEPTIDES AND PEPTIDE DERIVATIVES FOR THE TREATMENT OF Alpha-SYNUCLEIN-RELATED DISEASES
AU2002352170A1 (en) Anti-t cell immunotoxin fusion protein and its therapeutic use
AU2003246380A1 (en) Diagnostic and therapeutic use of tb2 gene and protein for neurodegenerative diseases
AU2003260301A1 (en) Diagnostic and therapeutic use of ensadin-0581 gene and protein for neurodegenerative diseases
AU2003278497A1 (en) Diagnostic and therapeutic use of ras-gtpase-activating sh3-domain-binding protein 2 (g3bp2) for neurodegenerative diseases
AU2003246592A1 (en) Tumour marker and the use thereof for the diagnosis and treatment of tumour diseases
AU2002364501A1 (en) Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
AU2003279312A1 (en) Diagnostic and therapeutic use of ensadin-0289 gene and protein for neurodegenerative diseases
AU2003257398A8 (en) Composite peptide compounds for diagnosis and treatment of diseases caused by prion proteins
AU2003271568A1 (en) Diagnostic and therapeutic use of thyroid hormone binding protein for neurodegenerative diseases
AU2003224080A1 (en) Diagnostic and therapeutic use of a golgi protein for neurodegenerative diseases
AU2003240746A1 (en) Diagnostic and therapeutic use of steroidogenic acute regulatory protein for neurodegenerative diseases
AU2003260460A1 (en) Diagnostic and therapeutic use of foap-13 polynucleotides and polypeptides for neurodegenerative diseases
AU2003242588A1 (en) Diagnostic and therapeutic use of cyp11a1 for neurodegenerative diseases
AU2003288127A1 (en) DIAGNOSTIC AND THERAPEUTIC USE OF H-Rev107 PROTEIN FOR ALZHEIMER DISEASE
AU2003222849A1 (en) Diagnostic and therapeutic use of ensadin-0255 gene and protein for neurodegenerative diseases
AU2003235635A1 (en) Diagnostic and therapeutic use of the voltage-gated ion channel scn2a for neurodegenerative diseases
AU2003232200A1 (en) Diagnostic and therapeutic use of vault polynucleotides and proteins for neurodegenerative diseases
AU2003244645A1 (en) Diagnostic and therapeutic use of a rab family gtp-binding protein for neurodegenerative diseases
AU2003224095A1 (en) Diagnostic and therapeutic use of an atp-binding cassette gene and protein for neurodegenerative diseases
AU2003214075A1 (en) Diagnostic and therapeutic use of ma onconeuronal antigens for neurodegenerative diseases

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase