AU2003268260B2 - Agents and methods for enhancing bone formation - Google Patents

Agents and methods for enhancing bone formation Download PDF

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Publication number
AU2003268260B2
AU2003268260B2 AU2003268260A AU2003268260A AU2003268260B2 AU 2003268260 B2 AU2003268260 B2 AU 2003268260B2 AU 2003268260 A AU2003268260 A AU 2003268260A AU 2003268260 A AU2003268260 A AU 2003268260A AU 2003268260 B2 AU2003268260 B2 AU 2003268260B2
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Australia
Prior art keywords
hydroxycholesterol
cells
oxysterol
group
oxysterols
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AU2003268260A
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AU2003268260A1 (en
Inventor
Farhad Parhami
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University of California San Diego UCSD
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University of California Berkeley
University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
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  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
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  • Wood Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
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AU2003268260A 2002-08-29 2003-08-28 Agents and methods for enhancing bone formation Ceased AU2003268260B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40671502P 2002-08-29 2002-08-29
US60/406,715 2002-08-29
PCT/US2003/027105 WO2004019884A2 (en) 2002-08-29 2003-08-28 Agents and methods for enhancing bone formation

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AU2003268260A1 AU2003268260A1 (en) 2004-03-19
AU2003268260B2 true AU2003268260B2 (en) 2008-04-10

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US (1) US7897588B2 (enExample)
EP (1) EP1556057A4 (enExample)
JP (1) JP2006503819A (enExample)
AU (1) AU2003268260B2 (enExample)
CA (1) CA2495882A1 (enExample)
WO (1) WO2004019884A2 (enExample)

Families Citing this family (39)

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CA2495882A1 (en) 2002-08-29 2004-03-11 The Regents Of The University Of California Agents and methods for enhancing bone formation
CA2529558A1 (en) * 2003-07-01 2005-01-13 Astellas Pharma Inc. Agent inducing increase in bone mass
US7318925B2 (en) 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
JP2007521232A (ja) 2003-08-08 2007-08-02 アブジェニックス・インコーポレーテッド 副甲状腺ホルモン（ｐｔｈ）に対する抗体およびその使用
WO2005020928A2 (en) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US8193312B2 (en) 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
US8188219B2 (en) * 2004-01-28 2012-05-29 The Regents Of The University Of California Bone morphogenic protein binding peptide
US8415302B2 (en) 2004-01-28 2013-04-09 The Regents Of The University Of California Surgical applications for BMP binding protein
MXPA06014576A (es) * 2004-06-24 2007-03-23 Galapagos Nv Agonistas de lxr para promover homeostasis osea.
US8753660B2 (en) * 2004-11-29 2014-06-17 The Regents Of The University Of California Activating extraction of demineralized bone matrix
US20090202660A1 (en) * 2005-04-07 2009-08-13 The Regents Of The University Of California Agents and Methods for Osteogenic Oxysterols Inhibition of Oxidative Stress on Osteogenic Cellular Differentiation
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