AU2003263660A1 - Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood - Google Patents

Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood

Info

Publication number
AU2003263660A1
AU2003263660A1 AU2003263660A AU2003263660A AU2003263660A1 AU 2003263660 A1 AU2003263660 A1 AU 2003263660A1 AU 2003263660 A AU2003263660 A AU 2003263660A AU 2003263660 A AU2003263660 A AU 2003263660A AU 2003263660 A1 AU2003263660 A1 AU 2003263660A1
Authority
AU
Australia
Prior art keywords
detection
down syndrome
maternal blood
prenatal diagnosis
rna markers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003263660A
Other languages
English (en)
Inventor
Evert Johannes Bunschoten
Cornelis Bartholomeus Maria Oudejans
Johannes Marinus Gerardus Van Vugt
Allerdien Visser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pantarhei Bioscience BV
Original Assignee
Pantarhei Bioscience BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantarhei Bioscience BV filed Critical Pantarhei Bioscience BV
Publication of AU2003263660A1 publication Critical patent/AU2003263660A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
AU2003263660A 2003-08-29 2003-08-29 Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood Abandoned AU2003263660A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL2003/000608 WO2005021793A1 (fr) 2003-08-29 2003-08-29 Diagnostic prenatal du syndrome de down par detection de marqueurs arn foetaux dans le sang maternel

Publications (1)

Publication Number Publication Date
AU2003263660A1 true AU2003263660A1 (en) 2005-03-16

Family

ID=34270789

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003263660A Abandoned AU2003263660A1 (en) 2003-08-29 2003-08-29 Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood

Country Status (2)

Country Link
AU (1) AU2003263660A1 (fr)
WO (1) WO2005021793A1 (fr)

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DE10344799A1 (de) * 2003-09-26 2005-04-14 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
TWI367260B (en) 2005-03-18 2012-07-01 Univ Hong Kong Chinese Method for detecting the presence of a fetus with trisomy 21 in a pregnant woman and kit thereof
JP5219516B2 (ja) * 2005-03-18 2013-06-26 ザ チャイニーズ ユニバーシティー オブ ホンコン 染色体異数性の検出方法
DE102005013846A1 (de) 2005-03-24 2006-10-05 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US10083273B2 (en) 2005-07-29 2018-09-25 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US8532930B2 (en) 2005-11-26 2013-09-10 Natera, Inc. Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals
US10081839B2 (en) 2005-07-29 2018-09-25 Natera, Inc System and method for cleaning noisy genetic data and determining chromosome copy number
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
GR1006121B (el) 2007-10-26 2008-10-24 ��������������� ������� ��������� ������ (40%) Η πρωτεϊνη serum amyloid p-component (sap,samp) ως προγνωστικος και διαγνωστικος δεικτης για τον προγεννητικο ελεγχο της τρισωμιας 21 (συνδρομο down)
ES2620431T3 (es) 2008-08-04 2017-06-28 Natera, Inc. Métodos para la determinación de alelos y de ploidía
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
CN102483406A (zh) * 2009-06-24 2012-05-30 健康公司-拉姆巴姆 用于分离胎盘来源微粒的方法和试剂盒以及它们用于诊断胎儿疾病的应用
EP2854056A3 (fr) 2009-09-30 2015-06-03 Natera, Inc. Procédés pour une classification de ploïdie prénatale non invasive
EP3660165B1 (fr) 2009-12-22 2023-01-04 Sequenom, Inc. Procédés et kits pour identifier une aneuploïdie
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
EP2854058A3 (fr) 2010-05-18 2015-10-28 Natera, Inc. Procédés pour une classification de ploïdie prénatale non invasive
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US10179937B2 (en) 2014-04-21 2019-01-15 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
ES2770342T3 (es) 2010-12-22 2020-07-01 Natera Inc Procedimientos para pruebas prenatales no invasivas de paternidad
CN103608818B (zh) 2011-02-09 2017-12-08 纳特拉公司 非侵入性产前倍性识别装置
US20150038358A1 (en) * 2011-12-01 2015-02-05 University Of Kansas Methods for detecting trisomy 21
US9605313B2 (en) 2012-03-02 2017-03-28 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
AU2013290102B2 (en) 2012-07-13 2018-11-15 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
EP2759602A1 (fr) * 2013-01-25 2014-07-30 Charité - Universitätsmedizin Berlin Procédés de diagnostic génétique prénatal non invasif
KR102241051B1 (ko) * 2013-02-28 2021-04-16 더 차이니즈 유니버시티 오브 홍콩 대량 동시 rna 서열분석에 의한 모체 혈장 전사물 분석
EP2971100A1 (fr) 2013-03-13 2016-01-20 Sequenom, Inc. Amorces pour analyse de la méthylation de l'adn
US10262755B2 (en) 2014-04-21 2019-04-16 Natera, Inc. Detecting cancer mutations and aneuploidy in chromosomal segments
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
US9499870B2 (en) 2013-09-27 2016-11-22 Natera, Inc. Cell free DNA diagnostic testing standards
EP3736344A1 (fr) 2014-03-13 2020-11-11 Sequenom, Inc. Méthodes et procédés d'évaluation non invasive de variations génétiques
WO2016183106A1 (fr) 2015-05-11 2016-11-17 Natera, Inc. Procédés et compositions pour la détermination de la ploïdie
WO2018067517A1 (fr) 2016-10-04 2018-04-12 Natera, Inc. Procédés pour caractériser une variation de nombre de copies à l'aide d'un séquençage de ligature de proximité
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
US10894976B2 (en) 2017-02-21 2021-01-19 Natera, Inc. Compositions, methods, and kits for isolating nucleic acids
CN107190073B (zh) * 2017-06-26 2020-12-15 中国人民解放军第一八一医院 hsa_circRNA_104907在唐氏综合征的诊断、治疗及预后中的应用
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
CN111979309B (zh) * 2019-05-21 2022-08-26 北京达微生物科技有限公司 用于三体综合征检测的组合套装
CN111411112B (zh) * 2020-05-19 2022-02-22 中国医科大学附属盛京医院 一种mapk6p2基因的靶向抑制剂及其用途
CN111808948A (zh) * 2020-07-29 2020-10-23 广西医科大学第一附属医院 环状RNA hsa_circ_0006687及其应用
CN113061653A (zh) * 2021-05-07 2021-07-02 济南国科医工科技发展有限公司 用于产前无创检测21三体综合征的pcr扩增组合物及检测试剂盒

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Publication number Priority date Publication date Assignee Title
US6664056B2 (en) * 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring

Also Published As

Publication number Publication date
WO2005021793A1 (fr) 2005-03-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase