AU2003263301A8 - Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate - Google Patents

Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Info

Publication number
AU2003263301A8
AU2003263301A8 AU2003263301A AU2003263301A AU2003263301A8 AU 2003263301 A8 AU2003263301 A8 AU 2003263301A8 AU 2003263301 A AU2003263301 A AU 2003263301A AU 2003263301 A AU2003263301 A AU 2003263301A AU 2003263301 A8 AU2003263301 A8 AU 2003263301A8
Authority
AU
Australia
Prior art keywords
morphine
preparation
tartrate
alternative processes
alternative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003263301A
Other versions
AU2003263301A1 (en
Inventor
John Whittall
Paul Mather
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stylacats Ltd
Original Assignee
Stylacats Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stylacats Ltd filed Critical Stylacats Ltd
Publication of AU2003263301A1 publication Critical patent/AU2003263301A1/en
Publication of AU2003263301A8 publication Critical patent/AU2003263301A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
AU2003263301A 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate Abandoned AU2003263301A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0220385.9 2002-09-03
GB0220385A GB2392670A (en) 2002-09-03 2002-09-03 (+)-Morphine production
PCT/GB2003/003805 WO2004022564A2 (en) 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Publications (2)

Publication Number Publication Date
AU2003263301A1 AU2003263301A1 (en) 2004-03-29
AU2003263301A8 true AU2003263301A8 (en) 2004-03-29

Family

ID=9943367

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003263301A Abandoned AU2003263301A1 (en) 2002-09-03 2003-09-03 Alternative processes for the preparation of d- (+) -morphine, and d- (+) - morphine tartrate

Country Status (3)

Country Link
AU (1) AU2003263301A1 (en)
GB (1) GB2392670A (en)
WO (1) WO2004022564A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8067597B2 (en) 2005-06-16 2011-11-29 Mallinckrodt Llc Synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
AU2008276385B2 (en) * 2007-07-17 2013-07-18 SpecGx LLC Preparation of N-alkylated opiates by reductive amination
ES2664252T3 (en) * 2008-09-16 2018-04-18 SpecGx, LLC Processes for the synthesis of five- and six-membered heterocyclic rings
JP5627594B2 (en) * 2008-12-02 2014-11-19 マリンクロッド エルエルシー Process for preparing hydrocodone using superacid
US8946419B2 (en) 2009-02-23 2015-02-03 Mallinckrodt Llc (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
JP2012518652A (en) * 2009-02-23 2012-08-16 マリンクロッド インコーポレイテッド (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
US8563727B2 (en) * 2009-02-23 2013-10-22 Mallinckrodt Llc (+)-morphinanium N-oxides and processes for their production
AU2010273253B2 (en) * 2009-07-16 2015-03-12 Mallinckrodt Llc (+) - morphinans as antagonists of Toll-like receptor 9 and therapeutic uses thereof
US10363251B2 (en) 2009-07-16 2019-07-30 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
CA2768199C (en) 2010-07-16 2018-08-28 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
CN104672142B (en) * 2015-02-13 2017-08-04 江苏大学 The preparation of diadactic structure Sinomenine derivate and medical usage
CN109666030B (en) * 2018-11-19 2021-04-27 兰州大学 Method for catalyzing asymmetric synthesis of codeine and morphine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495271A (en) * 1974-04-10 1977-12-14 Macfarlan Smith Ltd Dehydrohalogenation of codeinone derivatives
DE69030003T2 (en) * 1989-08-17 1997-09-18 Univ City MICROELECTRODES AND THEIR USE IN ELECTROCHEMICAL CIRCUITS WITH TELEMETRIC TRANSMISSION

Also Published As

Publication number Publication date
WO2004022564A2 (en) 2004-03-18
GB2392670A (en) 2004-03-10
AU2003263301A1 (en) 2004-03-29
WO2004022564A3 (en) 2004-07-01
GB0220385D0 (en) 2002-10-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase