AU2003259835A1 - Antibodies that immunospecifically bind to trail receptors - Google Patents
Antibodies that immunospecifically bind to trail receptorsInfo
- Publication number
- AU2003259835A1 AU2003259835A1 AU2003259835A AU2003259835A AU2003259835A1 AU 2003259835 A1 AU2003259835 A1 AU 2003259835A1 AU 2003259835 A AU2003259835 A AU 2003259835A AU 2003259835 A AU2003259835 A AU 2003259835A AU 2003259835 A1 AU2003259835 A1 AU 2003259835A1
- Authority
- AU
- Australia
- Prior art keywords
- antibodies
- immunospecifically bind
- trail receptors
- trail
- receptors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40338202P | 2002-08-15 | 2002-08-15 | |
US60/403,382 | 2002-08-15 | ||
US42573002P | 2002-11-13 | 2002-11-13 | |
US60/425,730 | 2002-11-13 | ||
US46805003P | 2003-05-06 | 2003-05-06 | |
US60/468,050 | 2003-05-06 | ||
PCT/US2003/025457 WO2004016753A2 (fr) | 2002-08-15 | 2003-08-15 | Anticorps se fixant de facon immunospecifique a des recepteurs trail |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003259835A8 AU2003259835A8 (en) | 2004-03-03 |
AU2003259835A1 true AU2003259835A1 (en) | 2004-03-03 |
Family
ID=31892094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003259835A Abandoned AU2003259835A1 (en) | 2002-08-15 | 2003-08-15 | Antibodies that immunospecifically bind to trail receptors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1534336A4 (fr) |
AU (1) | AU2003259835A1 (fr) |
CA (1) | CA2494372C (fr) |
WO (1) | WO2004016753A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8288439B2 (en) * | 2003-11-04 | 2012-10-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for the inhibition of HIV-1 replication |
CN101031319A (zh) * | 2003-12-11 | 2007-09-05 | 舍林股份公司 | 改善放射性标记药物的功效的放射增敏剂缀合物 |
US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
PE20090499A1 (es) | 2007-08-09 | 2009-05-18 | Boehringer Ingelheim Int | Anticuerpos anti-cd37 |
KR20110009095A (ko) | 2008-03-03 | 2011-01-27 | 더 유니버시티 오브 마이애미 | 동종 이계 암 세포-기반 면역 요법 |
JP2015517511A (ja) * | 2012-05-16 | 2015-06-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cd37抗体とice(イフォスファミド、カルボプラチン、エトポシド)の併用 |
ES2812208T3 (es) | 2013-03-14 | 2021-03-16 | Bristol Myers Squibb Co | Combinación de un agonista de DR5 y un antagonista de anti-PD-1 y métodos de uso |
US20180028521A1 (en) | 2016-07-29 | 2018-02-01 | Janssen Pharmaceutica Nv | Methods of Treating Prostate Cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002500877A (ja) * | 1998-01-26 | 2002-01-15 | ジェネンテク・インコーポレイテッド | 細胞死レセプター4(dr4)に対する抗体及びその使用 |
DK1303293T3 (da) * | 2000-07-27 | 2009-03-30 | Genentech Inc | Sekventiel indgivelse af CPT-11 og APO-2L-polypeptid |
NZ529359A (en) * | 2001-05-25 | 2007-04-27 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to a TR4 polypeptide or polypeptide fragment or variant of TR4 and their use in a medicament for treating cancer |
-
2003
- 2003-08-15 CA CA2494372A patent/CA2494372C/fr not_active Expired - Lifetime
- 2003-08-15 AU AU2003259835A patent/AU2003259835A1/en not_active Abandoned
- 2003-08-15 WO PCT/US2003/025457 patent/WO2004016753A2/fr not_active Application Discontinuation
- 2003-08-15 EP EP03788476A patent/EP1534336A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1534336A2 (fr) | 2005-06-01 |
WO2004016753A2 (fr) | 2004-02-26 |
WO2004016753A3 (fr) | 2004-06-17 |
EP1534336A4 (fr) | 2005-12-14 |
AU2003259835A8 (en) | 2004-03-03 |
CA2494372A1 (fr) | 2004-02-26 |
CA2494372C (fr) | 2013-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |