AU2001297702A1 - Antibodies that immunospecifically bind to trail receptors - Google Patents

Antibodies that immunospecifically bind to trail receptors

Info

Publication number
AU2001297702A1
AU2001297702A1 AU2001297702A AU2001297702A AU2001297702A1 AU 2001297702 A1 AU2001297702 A1 AU 2001297702A1 AU 2001297702 A AU2001297702 A AU 2001297702A AU 2001297702 A AU2001297702 A AU 2001297702A AU 2001297702 A1 AU2001297702 A1 AU 2001297702A1
Authority
AU
Australia
Prior art keywords
antibodies
immunospecifically bind
trail receptors
trail
receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001297702A
Inventor
Victor Roschke
Craig A. Rosen
Steven M. Ruben
Theodora Salcedo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US24661200P priority Critical
Priority to US60/246,612 priority
Priority to US24884700P priority
Priority to US60/248,847 priority
Priority to US60/252,904 priority
Priority to US25290400P priority
Priority to US29501801P priority
Priority to US60/295,018 priority
Priority to US60/327,359 priority
Priority to US32735901P priority
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Priority to PCT/US2001/042996 priority patent/WO2002079377A2/en
Publication of AU2001297702A1 publication Critical patent/AU2001297702A1/en
Application status is Abandoned legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
AU2001297702A 2000-11-08 2001-11-07 Antibodies that immunospecifically bind to trail receptors Abandoned AU2001297702A1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
US24661200P true 2000-11-08 2000-11-08
US60/246,612 2000-11-08
US24884700P true 2000-11-16 2000-11-16
US60/248,847 2000-11-16
US25290400P true 2000-11-27 2000-11-27
US60/252,904 2000-11-27
US29501801P true 2001-06-04 2001-06-04
US60/295,018 2001-06-04
US32735901P true 2001-10-09 2001-10-09
US60/327,359 2001-10-09
PCT/US2001/042996 WO2002079377A2 (en) 2000-11-08 2001-11-07 Antibodies that immunospecifically bind to trail receptors

Publications (1)

Publication Number Publication Date
AU2001297702A1 true AU2001297702A1 (en) 2002-10-15

Family

ID=27540243

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001297702A Abandoned AU2001297702A1 (en) 2000-11-08 2001-11-07 Antibodies that immunospecifically bind to trail receptors

Country Status (4)

Country Link
EP (1) EP1339426A4 (en)
AU (1) AU2001297702A1 (en)
CA (1) CA2426710A1 (en)
WO (1) WO2002079377A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7279160B2 (en) 2000-05-02 2007-10-09 The Uab Research Foundation Combinations of DR5 antibodies and other therapeutic agents
TWI318983B (en) 2000-05-02 2010-01-01 Uab Research Foundation An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
US7476383B2 (en) 2000-05-02 2009-01-13 The Uab Research Foundation Antibody selective for DR4 and uses thereof
US7115717B2 (en) 2001-05-18 2006-10-03 Kirin Beer Kabushiki Kaisha Anti-TRAIL-R antibodies
EP1531162A1 (en) * 2003-11-14 2005-05-18 Hans Konrad Müller-Hermelink Adenocarcinoma specific antibody SAM-6, and uses thereof
JP5562521B2 (en) 2005-02-02 2014-07-30 ザ ユーエービー リサーチ ファンデーション Drug and a method for reducing the resistance to apoptosis inducing death receptor agonist
WO2008094319A2 (en) 2007-02-01 2008-08-07 The Board Of Regents Of The University Of Texas Sytem Methods and compositions of trail-death receptor agonists/activators
US10150800B2 (en) 2013-03-15 2018-12-11 Zyngenia, Inc. EGFR-binding modular recognition domains

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU708239B2 (en) * 1995-06-29 1999-07-29 Immunex Corporation Cytokine that induces apoptosis
EP1012274B2 (en) * 1997-01-28 2011-06-15 Human Genome Sciences, Inc. Death domain containing receptor 4 (dr4: death receptor 4), member of the tnf-receptor superfamily and binding to trail (ap0-2l)
US6072047A (en) * 1997-02-13 2000-06-06 Immunex Corporation Receptor that binds trail
AU9386398A (en) * 1997-09-12 1999-03-29 Biogen, Inc. Cysteine rich receptors: trail
JP2002500877A (en) * 1998-01-26 2002-01-15 ジェネンテク・インコーポレイテッド Antibodies and uses thereof to cell death receptor 4 (dr4)
IL139419D0 (en) * 1998-06-12 2001-11-25 Genentech Inc Monoclonal antibodies, cross-reactive antibodies and method for producing the same
ES2609016T3 (en) * 2000-06-16 2017-04-18 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to BLyS
GB0020685D0 (en) * 2000-08-22 2000-10-11 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CA2426710A1 (en) 2002-10-10
WO2002079377A2 (en) 2002-10-10
EP1339426A2 (en) 2003-09-03
EP1339426A4 (en) 2004-06-30
WO2002079377A3 (en) 2003-03-13

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase