AU2003259713A1 - Oncokinase fusion polypeptides associated with hyperproliferative and related disorders, nucleic acids encoding the same and methods for detecting and identifying the same - Google Patents
Oncokinase fusion polypeptides associated with hyperproliferative and related disorders, nucleic acids encoding the same and methods for detecting and identifying the sameInfo
- Publication number
- AU2003259713A1 AU2003259713A1 AU2003259713A AU2003259713A AU2003259713A1 AU 2003259713 A1 AU2003259713 A1 AU 2003259713A1 AU 2003259713 A AU2003259713 A AU 2003259713A AU 2003259713 A AU2003259713 A AU 2003259713A AU 2003259713 A1 AU2003259713 A1 AU 2003259713A1
- Authority
- AU
- Australia
- Prior art keywords
- same
- hyperproliferative
- identifying
- detecting
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000004927 fusion Effects 0.000 title 1
- 230000003463 hyperproliferative effect Effects 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40233002P | 2002-08-09 | 2002-08-09 | |
| US60/402,330 | 2002-08-09 | ||
| US44049103P | 2003-01-16 | 2003-01-16 | |
| US60/440,491 | 2003-01-16 | ||
| PCT/US2003/024992 WO2004015082A2 (en) | 2002-08-09 | 2003-08-08 | Oncokinase fusion polypeptides associated with hyperproliferative and related disorders, nucleic acids encoding the same and methods for detecting and identifying the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003259713A1 true AU2003259713A1 (en) | 2004-02-25 |
| AU2003259713A8 AU2003259713A8 (en) | 2004-02-25 |
Family
ID=31720590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003259713A Abandoned AU2003259713A1 (en) | 2002-08-09 | 2003-08-08 | Oncokinase fusion polypeptides associated with hyperproliferative and related disorders, nucleic acids encoding the same and methods for detecting and identifying the same |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US7195876B2 (https=) |
| EP (1) | EP1576129A4 (https=) |
| JP (2) | JP4588447B2 (https=) |
| AU (1) | AU2003259713A1 (https=) |
| WO (1) | WO2004015082A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE302771T1 (de) * | 2001-12-27 | 2005-09-15 | Theravance Inc | Indolinon-derivative als protein-kinasehemmer |
| US7595154B2 (en) | 2002-06-13 | 2009-09-29 | Oregon Health And Science University | Method of detecting a neoplasia associated with an activating platelet derived growth factor receptor alpha (PDGFRA) mutation |
| JP4588447B2 (ja) * | 2002-08-09 | 2010-12-01 | セラヴァンス, インコーポレーテッド | 過剰増殖および関連疾患に関連するオンコキナーゼ融合ポリペプチド、これをコードする核酸、ならびにこれを検出する方法および同定する方法 |
| CA2526594C (en) * | 2003-05-27 | 2011-11-08 | Robert Per Haegerkvist | Use of tyrosine kinase inhibitors to treat diabetes |
| US20050171182A1 (en) * | 2003-12-11 | 2005-08-04 | Roger Briesewitz | Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases |
| WO2007100880A1 (en) * | 2006-02-28 | 2007-09-07 | Amgen Inc. | Cinnoline and quinazoline derivates as phosphodiesterase 10 inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2057854C (en) * | 1989-05-22 | 2000-01-11 | James D. Kelly | Pdgf .alpha.-receptor |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
| CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
| WO2000078952A2 (en) * | 1999-06-17 | 2000-12-28 | Incyte Genomics, Inc. | Human rna metabolism proteins (rmep) |
| SI1255752T1 (sl) | 2000-02-15 | 2007-12-31 | Pharmacia & Upjohn Co Llc | S pirolom substituirani zaviralci 2-indolinon protein kinaza |
| AU8544901A (en) | 2000-08-18 | 2002-03-04 | Cor Therapeutics Inc | Quinazoline derivatives as kinase inhibitors |
| ATE302771T1 (de) | 2001-12-27 | 2005-09-15 | Theravance Inc | Indolinon-derivative als protein-kinasehemmer |
| JP4588447B2 (ja) * | 2002-08-09 | 2010-12-01 | セラヴァンス, インコーポレーテッド | 過剰増殖および関連疾患に関連するオンコキナーゼ融合ポリペプチド、これをコードする核酸、ならびにこれを検出する方法および同定する方法 |
-
2003
- 2003-08-08 JP JP2004527956A patent/JP4588447B2/ja not_active Expired - Fee Related
- 2003-08-08 AU AU2003259713A patent/AU2003259713A1/en not_active Abandoned
- 2003-08-08 EP EP03785118A patent/EP1576129A4/en not_active Withdrawn
- 2003-08-08 US US10/637,356 patent/US7195876B2/en not_active Expired - Lifetime
- 2003-08-08 WO PCT/US2003/024992 patent/WO2004015082A2/en not_active Ceased
-
2007
- 2007-02-15 US US11/706,519 patent/US7585653B2/en not_active Expired - Lifetime
- 2007-12-11 US US12/001,328 patent/US7604944B2/en not_active Expired - Lifetime
-
2009
- 2009-08-26 US US12/548,170 patent/US20100112661A1/en not_active Abandoned
-
2010
- 2010-07-23 JP JP2010166564A patent/JP2010279376A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1576129A2 (en) | 2005-09-21 |
| US7585653B2 (en) | 2009-09-08 |
| US20040045044A1 (en) | 2004-03-04 |
| WO2004015082A3 (en) | 2007-04-26 |
| JP2010279376A (ja) | 2010-12-16 |
| US20100112661A1 (en) | 2010-05-06 |
| JP2006515983A (ja) | 2006-06-15 |
| EP1576129A4 (en) | 2008-01-23 |
| WO2004015082A2 (en) | 2004-02-19 |
| US20080102472A1 (en) | 2008-05-01 |
| JP4588447B2 (ja) | 2010-12-01 |
| AU2003259713A8 (en) | 2004-02-25 |
| US20090087881A1 (en) | 2009-04-02 |
| US7195876B2 (en) | 2007-03-27 |
| US7604944B2 (en) | 2009-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |