AU2003254450A1 - Process for preparing of paclitaxel - Google Patents
Process for preparing of paclitaxelInfo
- Publication number
- AU2003254450A1 AU2003254450A1 AU2003254450A AU2003254450A AU2003254450A1 AU 2003254450 A1 AU2003254450 A1 AU 2003254450A1 AU 2003254450 A AU2003254450 A AU 2003254450A AU 2003254450 A AU2003254450 A AU 2003254450A AU 2003254450 A1 AU2003254450 A1 AU 2003254450A1
- Authority
- AU
- Australia
- Prior art keywords
- paclitaxel
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229930012538 Paclitaxel Natural products 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960001592 paclitaxel Drugs 0.000 title 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0216412.7A GB0216412D0 (en) | 2002-07-15 | 2002-07-15 | Chemical process |
| GB0216412.7 | 2002-07-15 | ||
| PCT/GB2003/003041 WO2004007473A1 (en) | 2002-07-15 | 2003-07-15 | Process for preparing of paclitaxel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003254450A1 true AU2003254450A1 (en) | 2004-02-02 |
Family
ID=9940483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003254450A Abandoned AU2003254450A1 (en) | 2002-07-15 | 2003-07-15 | Process for preparing of paclitaxel |
Country Status (6)
| Country | Link |
|---|---|
| AP (1) | AP2005003229A0 (en) |
| AU (1) | AU2003254450A1 (en) |
| GB (2) | GB0216412D0 (en) |
| RU (1) | RU2326876C2 (en) |
| WO (1) | WO2004007473A1 (en) |
| ZA (1) | ZA200501234B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1303077C (en) * | 2004-01-16 | 2007-03-07 | 桂林晖昂生化药业有限责任公司 | Preparation process for synthesized taxane |
| CN101274924B (en) * | 2007-03-27 | 2010-11-10 | 中国科学院大连化学物理研究所 | Preparation for paclitaxel and derivatives thereof |
| US8791279B2 (en) * | 2010-12-13 | 2014-07-29 | Yung Shin Pharm. Ind. Co., Ltd. | Process for preparing taxoids from baccatin derivatives using lewis acid catalyst |
| CN104250235B (en) * | 2014-09-24 | 2016-10-05 | 江苏红豆杉药业有限公司 | A kind of preparation method of paclitaxel |
| CN105418543A (en) * | 2015-12-01 | 2016-03-23 | 贵州大学 | Method for extracting baccatin III reference substance from taxus chinensis plants |
| CN109438395A (en) * | 2018-12-25 | 2019-03-08 | 重庆市碚圣医药科技股份有限公司 | A kind of synthetic method and products thereof of Japanese yew alcohol intermediate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017656A1 (en) * | 1996-10-24 | 1998-04-30 | Institute Armand-Frappier | A family of canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof |
| US6020507A (en) * | 1998-03-02 | 2000-02-01 | Bristol-Myers Squibb Company | Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile |
-
2002
- 2002-07-15 GB GBGB0216412.7A patent/GB0216412D0/en not_active Ceased
-
2003
- 2003-07-15 AP AP2005003229A patent/AP2005003229A0/en unknown
- 2003-07-15 RU RU2005102395/04A patent/RU2326876C2/en not_active IP Right Cessation
- 2003-07-15 AU AU2003254450A patent/AU2003254450A1/en not_active Abandoned
- 2003-07-15 GB GB0500809A patent/GB2405637B/en not_active Expired - Fee Related
- 2003-07-15 WO PCT/GB2003/003041 patent/WO2004007473A1/en not_active Application Discontinuation
-
2005
- 2005-02-11 ZA ZA200501234A patent/ZA200501234B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200501234B (en) | 2006-10-25 |
| GB2405637A (en) | 2005-03-09 |
| RU2005102395A (en) | 2006-06-10 |
| GB2405637B (en) | 2006-02-22 |
| AP2005003229A0 (en) | 2005-03-31 |
| GB0216412D0 (en) | 2002-08-21 |
| RU2326876C2 (en) | 2008-06-20 |
| GB0500809D0 (en) | 2005-02-23 |
| WO2004007473A1 (en) | 2004-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |