AU2003253197A8 - Targeted gene modification by single-stranded dna oligonucleotides - Google Patents

Targeted gene modification by single-stranded dna oligonucleotides

Info

Publication number
AU2003253197A8
AU2003253197A8 AU2003253197A AU2003253197A AU2003253197A8 AU 2003253197 A8 AU2003253197 A8 AU 2003253197A8 AU 2003253197 A AU2003253197 A AU 2003253197A AU 2003253197 A AU2003253197 A AU 2003253197A AU 2003253197 A8 AU2003253197 A8 AU 2003253197A8
Authority
AU
Australia
Prior art keywords
stranded dna
targeted gene
dna oligonucleotides
gene modification
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003253197A
Other versions
AU2003253197A1 (en
Inventor
Henricus Petrus Joseph T Riele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlands Kanker Instituut
Original Assignee
Nederlands Kanker Instituut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlands Kanker Instituut filed Critical Nederlands Kanker Instituut
Publication of AU2003253197A8 publication Critical patent/AU2003253197A8/en
Publication of AU2003253197A1 publication Critical patent/AU2003253197A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2003253197A 2002-08-13 2003-08-13 Targeted gene modification by single-stranded dna oligonucleotides Abandoned AU2003253197A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0218803A GB0218803D0 (en) 2002-08-13 2002-08-13 Targeted gene modification by single-standed DNA oligonucleotides
GB0218803.5 2002-08-13
PCT/IB2003/003699 WO2004015117A2 (en) 2002-08-13 2003-08-13 Targeted gene modification by single-stranded dna oligonucleotides

Publications (2)

Publication Number Publication Date
AU2003253197A8 true AU2003253197A8 (en) 2004-02-25
AU2003253197A1 AU2003253197A1 (en) 2004-02-25

Family

ID=9942224

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003253197A Abandoned AU2003253197A1 (en) 2002-08-13 2003-08-13 Targeted gene modification by single-stranded dna oligonucleotides

Country Status (3)

Country Link
AU (1) AU2003253197A1 (en)
GB (1) GB0218803D0 (en)
WO (1) WO2004015117A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011058555A1 (en) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. A method of editing dna in a cell and constructs capable of same
WO2014102688A1 (en) * 2012-12-27 2014-07-03 Cellectis New design matrix for improvement of homology-directed gene targeting
EP3498837A4 (en) * 2016-08-12 2020-04-15 Nexuspiral Inc. Genome editing method
WO2021186913A1 (en) * 2020-03-20 2021-09-23 国立大学法人筑波大学 Method for modifying methylated state of genomic dna
JPWO2022249775A1 (en) * 2021-05-27 2022-12-01

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014092A1 (en) * 1989-05-18 1990-11-29 Cell Genesys, Inc. Single-strand site-directed modification of mammalian genes in vivo
AU2515992A (en) * 1991-08-20 1993-03-16 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
EP0656747A4 (en) * 1992-08-21 1997-05-07 Univ California Composition and method for altering dna sequences by homologous recombination.
WO1996040271A1 (en) * 1995-06-07 1996-12-19 Yale University Treatment of hemoglobinopathies
DK0842289T3 (en) * 1995-07-26 2005-02-14 Mixis France Sa Homologous recombination in eukaryotic cells with inactivated mismatch repair
AU772879B2 (en) * 1998-08-12 2004-05-13 Napro Biotherapeutics, Inc. Domain specific gene evolution
US6271360B1 (en) * 1999-08-27 2001-08-07 Valigen (Us), Inc. Single-stranded oligodeoxynucleotide mutational vectors
EP1152058A1 (en) * 2000-05-03 2001-11-07 Institut Curie Methods and compositions for effecting homologous recombination
US20020119570A1 (en) * 2000-09-25 2002-08-29 Kyonggeun Yoon Targeted gene correction by single-stranded oligodeoxynucleotides

Also Published As

Publication number Publication date
GB0218803D0 (en) 2002-09-18
AU2003253197A1 (en) 2004-02-25
WO2004015117A2 (en) 2004-02-19
WO2004015117A3 (en) 2004-06-03

Similar Documents

Publication Publication Date Title
HK1187949A1 (en) Random array dna analysis by hybridization dna
EP1731525A4 (en) Nucleotide derivatives and dna microarray
AU2003254334A1 (en) Rna-interference by single-stranded rna molecules
GB0318428D0 (en) Gene drivers
EP1590002A4 (en) Small interference rna gene therapy
EP1670944A4 (en) Microplates useful for conducting thermocycled nucleotide amplification
AU2003290597A8 (en) Modified oligonucleotides for use in rna interference
IL192165A0 (en) Improved targeted nucleotide exchange with propynyl modified oligonucleotides
AU2003304094A8 (en) Nucleic acid sequence detection using multiplexed oligonucleotide pcr
EP1633871A4 (en) Double-stranded nucleic acid
AU2003254597A8 (en) Dna chip based genetic typing
HK1073669A1 (en) Nucleic acid constructs for gene expression
AU2003279509A8 (en) Targeted double stranded rna mediated cell killing
AU2003253197A8 (en) Targeted gene modification by single-stranded dna oligonucleotides
EP1399541A4 (en) N4 virion single-stranded dna dependent rna polymerase
AU2003296087A1 (en) Nucleotide derivatives and dna microarray
AU2003245407A8 (en) Improvements for combinatorial oligonucleotide pcr
GB0228614D0 (en) Oligonucleotide guided analysis of gene expression
EP1570074A4 (en) Genotyping of deafness by oligonucleotide microarray analysis
EP1652917A4 (en) Rna capable of inhibiting expression of klf5 gene
EP1688489A4 (en) Method of selecting genomic dna fragment
AU2003245575A1 (en) Oligonucleotide directed misfolding of rna
ZA200502005B (en) Non-sequence complementary antiviral oligonucleotides
ZA200509813B (en) Double-stranded nucleic acid
GB0303924D0 (en) Modified nucleotides

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase