AU2003245804A1 - Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion - Google Patents

Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion

Info

Publication number
AU2003245804A1
AU2003245804A1 AU2003245804A AU2003245804A AU2003245804A1 AU 2003245804 A1 AU2003245804 A1 AU 2003245804A1 AU 2003245804 A AU2003245804 A AU 2003245804A AU 2003245804 A AU2003245804 A AU 2003245804A AU 2003245804 A1 AU2003245804 A1 AU 2003245804A1
Authority
AU
Australia
Prior art keywords
hazard
aqueous
application
aqueous emulsion
microencapsulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003245804A
Other languages
English (en)
Other versions
AU2003245804A8 (en
Inventor
Tuo Jin
Hua Zhu
Jiahao Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2003245804A1 publication Critical patent/AU2003245804A1/en
Publication of AU2003245804A8 publication Critical patent/AU2003245804A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AU2003245804A 2002-06-03 2003-06-03 Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion Abandoned AU2003245804A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US38497102P 2002-06-03 2002-06-03
US60/384,971 2002-06-03
US41810002P 2002-10-11 2002-10-11
US60/418,100 2002-10-11
US10/291,327 US6998393B2 (en) 2000-06-23 2002-11-08 Aquespheres, their preparation and uses thereof
US10/291,327 2002-11-08
PCT/CN2003/000431 WO2003101600A2 (en) 2002-06-03 2003-06-03 Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion

Publications (2)

Publication Number Publication Date
AU2003245804A1 true AU2003245804A1 (en) 2003-12-19
AU2003245804A8 AU2003245804A8 (en) 2003-12-19

Family

ID=27404043

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003245804A Abandoned AU2003245804A1 (en) 2002-06-03 2003-06-03 Hazard-free microencapsulation for structurally delicate agents, an application of stable aqueous-aqueous emulsion

Country Status (7)

Country Link
US (2) US6998393B2 (OSRAM)
EP (1) EP1572341A4 (OSRAM)
JP (1) JP2006504636A (OSRAM)
CN (1) CN102247327A (OSRAM)
AU (1) AU2003245804A1 (OSRAM)
CA (1) CA2487867A1 (OSRAM)
WO (1) WO2003101600A2 (OSRAM)

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US6998393B2 (en) * 2000-06-23 2006-02-14 Biopharm Solutions, Inc. Aquespheres, their preparation and uses thereof
US9186322B2 (en) * 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
BRPI0404983A (pt) * 2004-09-03 2006-05-02 Nanocore Biotecnologia Ltda composições imunogênicas
MX2007013356A (es) * 2005-04-27 2008-03-26 Baxter Int Microparticulas modificadas en la superficie y metodos de formacion y uso de las mismas.
US20070015689A1 (en) * 2005-06-23 2007-01-18 Alza Corporation Complexation of metal ions with polypeptides
US8932633B2 (en) * 2005-08-29 2015-01-13 Biopharm Solutions Inc. Polysaccharide microparticles containing biological agents: their preparation and applications
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
WO2008060786A2 (en) * 2006-10-06 2008-05-22 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
US9574128B2 (en) 2007-07-17 2017-02-21 Schlumberger Technology Corporation Polymer delivery in well treatment applications
US8043999B2 (en) * 2007-07-17 2011-10-25 Schlumberger Technology Corporation Stabilizing biphasic concentrates through the addition of small amounts of high molecular weight polyelectrolytes
US9475974B2 (en) * 2007-07-17 2016-10-25 Schlumberger Technology Corporation Controlling the stability of water in water emulsions
US7703527B2 (en) * 2007-11-26 2010-04-27 Schlumberger Technology Corporation Aqueous two-phase emulsion gel systems for zone isolation
US7703521B2 (en) * 2008-02-19 2010-04-27 Schlumberger Technology Corporation Polymeric microspheres as degradable fluid loss additives in oilfield applications
ES2385762T3 (es) 2008-09-30 2012-07-31 The Procter & Gamble Company Composición que comprende microcápsulas
US20100179076A1 (en) * 2009-01-15 2010-07-15 Sullivan Philip F Filled Systems From Biphasic Fluids
US7950459B2 (en) * 2009-01-15 2011-05-31 Schlumberger Technology Corporation Using a biphasic solution as a recyclable coiled tubing cleanout fluid
US20100184631A1 (en) * 2009-01-16 2010-07-22 Schlumberger Technology Corporation Provision of viscous compositions below ground
US20100184630A1 (en) * 2009-01-16 2010-07-22 Sullivan Philip F Breaking the rheology of a wellbore fluid by creating phase separation
WO2010102066A1 (en) 2009-03-05 2010-09-10 Bend Research, Inc. Dextran polymer powder for inhalation administration of pharmaceuticals
WO2010111132A2 (en) 2009-03-27 2010-09-30 Bend Research, Inc. Spray-drying process
JP5618307B2 (ja) * 2009-07-09 2014-11-05 国立大学法人九州大学 水溶性薬物キャリア及びその製造方法
EP2611529B1 (en) 2010-09-03 2019-01-23 Bend Research, Inc. Spray-drying method
PT2611530T (pt) 2010-09-03 2019-05-09 Bend Res Inc Aparelho de secagem por pulverização e métodos de utilização do mesmo
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
EP2618924A1 (en) 2010-09-24 2013-07-31 Bend Research, Inc. High-temperature spray drying process and apparatus
US9060938B2 (en) 2011-05-10 2015-06-23 Bend Research, Inc. Pharmaceutical compositions of active agents and cationic dextran polymer derivatives
PL2892524T3 (pl) 2012-09-04 2021-10-25 Eleison Pharmaceuticals, Llc Zapobieganie nawrotom płucnym przy użyciu cisplatyny w kompleksie z lipidami
US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same
WO2016046845A1 (en) * 2014-09-25 2016-03-31 Manu Chaudhary Stealth, targeted nanoparticles (stn) for oral drug delivery
EP3212169B1 (en) 2014-10-31 2021-01-13 Bend Research, Inc. Process for forming active domains dispersed in a matrix
CN105571673B (zh) * 2015-12-11 2019-01-18 大连民族大学 一种脂质体包封体积的测定方法
CN105509836B (zh) * 2015-12-11 2019-01-18 大连民族大学 一种脂质体包封体积的快速测定方法
BR112018016774A2 (pt) 2016-02-16 2018-12-26 Strongbridge Ireland Limited veldoreotídeo com fraca solubilidade em condições fisiológicas para o uso no tratamento da acromegalia, câncer em acromegalia, tumores que expressam sst-r5, diabetes tipo 2, hiperglicemia e tumores relacionados a hormônio
EP3484450A4 (en) * 2016-07-18 2020-04-01 Tissuegen, Inc. METHODS AND COMPOSITIONS FOR MAINTAINING THE CONFORMATION AND STRUCTURAL INTEGRITY OF BIOMOLECULES
CN112203690A (zh) 2018-01-12 2021-01-08 哈佛大学校长及研究员协会 与具有粘附颗粒的巨噬细胞和/或单核细胞有关的组合物和方法
AU2020287620B2 (en) * 2019-06-07 2025-12-18 President And Fellows Of Harvard College Compositions and methods relating to erythrocytes with adhered particles

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JP2653255B2 (ja) * 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
US5716644A (en) 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5827707A (en) 1995-06-07 1998-10-27 Neocrin Company Method for manufacturing minimal volume capsules containing biological materials
US6395302B1 (en) * 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
DK1071407T3 (da) * 1999-01-18 2014-10-20 Lg Life Sciences Ltd Lipofile mikropartikler indeholdende et proteinlægemiddel eller et antigen og formulering omhandlende samme
US6998393B2 (en) * 2000-06-23 2006-02-14 Biopharm Solutions, Inc. Aquespheres, their preparation and uses thereof
US6805879B2 (en) * 2000-06-23 2004-10-19 Biopharm Solutions Inc. Stable polymer aqueous/aqueous emulsion system and uses thereof
SE0201599D0 (sv) * 2002-03-21 2002-05-30 Skyepharma Ab Microparticles

Also Published As

Publication number Publication date
WO2003101600A2 (en) 2003-12-11
US20060121121A1 (en) 2006-06-08
CN102247327A (zh) 2011-11-23
US20030059402A1 (en) 2003-03-27
EP1572341A2 (en) 2005-09-14
AU2003245804A8 (en) 2003-12-19
CA2487867A1 (en) 2003-12-11
WO2003101600A3 (en) 2007-12-13
JP2006504636A (ja) 2006-02-09
US6998393B2 (en) 2006-02-14
EP1572341A4 (en) 2008-11-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase