AU2003230935B2 - Methods of simultaneously treating ocular rosacea and acne rosacea - Google Patents

Methods of simultaneously treating ocular rosacea and acne rosacea Download PDF

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Publication number
AU2003230935B2
AU2003230935B2 AU2003230935A AU2003230935A AU2003230935B2 AU 2003230935 B2 AU2003230935 B2 AU 2003230935B2 AU 2003230935 A AU2003230935 A AU 2003230935A AU 2003230935 A AU2003230935 A AU 2003230935A AU 2003230935 B2 AU2003230935 B2 AU 2003230935B2
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AU
Australia
Prior art keywords
hydrogen
amino
halogen
dimethylamino
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003230935A
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English (en)
Other versions
AU2003230935A1 (en
Inventor
Robert A. Ashley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagenex Pharmaceuticals Inc
Original Assignee
Collagenex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Collagenex Pharmaceuticals Inc filed Critical Collagenex Pharmaceuticals Inc
Publication of AU2003230935A1 publication Critical patent/AU2003230935A1/en
Application granted granted Critical
Publication of AU2003230935B2 publication Critical patent/AU2003230935B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003230935A 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea Ceased AU2003230935B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37314102P 2002-04-16 2002-04-16
US60/373,141 2002-04-16
PCT/US2003/011686 WO2003088906A2 (en) 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea

Publications (2)

Publication Number Publication Date
AU2003230935A1 AU2003230935A1 (en) 2003-11-03
AU2003230935B2 true AU2003230935B2 (en) 2008-08-07

Family

ID=29250974

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003230935A Ceased AU2003230935B2 (en) 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea

Country Status (8)

Country Link
US (1) US7008631B2 (https=)
EP (2) EP1494681A4 (https=)
JP (1) JP2005523313A (https=)
KR (1) KR20050005444A (https=)
AU (1) AU2003230935B2 (https=)
CA (1) CA2476792A1 (https=)
NZ (1) NZ534613A (https=)
WO (1) WO2003088906A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US7211267B2 (en) * 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
US8192749B2 (en) * 2003-04-16 2012-06-05 Galderma Laboratories Inc. Methods of simultaneously treating ocular rosacea and acne rosacea
ES2534827T3 (es) 2003-04-07 2015-04-29 Supernus Pharmaceuticals, Inc. Formulaciones de tetraciclinas en dosis única diaria
CN103040773A (zh) * 2003-07-25 2013-04-17 沃纳奇尔科特有限责任公司 多西环素金属络合物固体剂型
WO2005089259A2 (en) * 2004-03-12 2005-09-29 Collagenex Pharmaceuticals, Inc. Method for treating aortic stenosis with non-antibacterial tetracycline formulations
US8252776B2 (en) * 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
PT2120963T (pt) * 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
PL2109602T3 (pl) 2006-12-21 2014-09-30 Paratek Pharm Innc Pochodne tetracyliny do leczenia zakażeń bakteryjnych, wirusowych i pasożytniczych
BRPI0808410A2 (pt) * 2007-02-28 2015-06-23 Aciex Therapeutics Inc Métodos e composições para normalizar secreções da glândula meibomiana
WO2008121107A1 (en) * 2007-04-02 2008-10-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
US20080305186A1 (en) * 2007-06-11 2008-12-11 Board Of Regents, The University Of Texas System Method and Composition for the Treatment of Cardiac Hypertrophy
US8107283B2 (en) * 2009-01-12 2012-01-31 Macronix International Co., Ltd. Method for setting PCRAM devices
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
CN104902892A (zh) * 2012-02-02 2015-09-09 悉尼大学 泪液膜稳定性的改进
FR3000396A1 (fr) * 2012-12-31 2014-07-04 Galderma Res & Dev Combinaison de laropiprant et de doxycycline pour le traitement de la rosacee
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
FR3026010B1 (fr) * 2014-09-18 2016-11-04 Galderma Sa Compositions comprenant un compose de la famille des avermectines et de la doxycycline pour le traitement de la rosacee
FR3064482B1 (fr) * 2017-04-03 2020-11-13 Horus Pharma Composition topique de doxycycline
CN111818927A (zh) 2018-01-07 2020-10-23 雷迪博士实验室有限公司 用于治疗炎性皮肤疾病的米诺环素
WO2020058504A1 (en) * 2018-09-22 2020-03-26 Novaliq Gmbh Ophthalmic compositions for treatment of ocular surface damage and symptoms of dryness
CN111499545B (zh) * 2020-04-27 2022-05-03 武汉英纳氏药业有限公司 一种对氨基取代苯酚类化合物的制备方法
WO2024008951A1 (en) * 2022-07-08 2024-01-11 Icm (Institut Du Cerveau Et De La Moelle Épinière) Tetracycline derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908838A (en) * 1998-02-19 1999-06-01 Medics Pharmaceutical Corporation Method for the treatment of acne
WO1999058131A1 (en) * 1998-05-08 1999-11-18 University Of Miami Use of tetracyclines for treating meibomian gland disease
US6015803A (en) * 1998-05-04 2000-01-18 Wirostko; Emil Antibiotic treatment of age-related macular degeneration

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957918A (en) * 1988-06-09 1990-09-18 Leonard Bloom Topical treatment of blepharitis
US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
US6071541A (en) * 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US6432934B1 (en) 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
US6384081B2 (en) 1998-10-09 2002-05-07 Charles L. Berman Treatment of diseases of the eye characterized by the formation of metalloproteinase
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
US6495158B1 (en) * 2001-01-19 2002-12-17 Lec Tec Corporation Acne patch
AU2002303250B2 (en) * 2001-04-05 2006-05-25 Collagenex Pharmaceuticals, Inc. Methods of treating acne
US20040092491A1 (en) 2002-11-09 2004-05-13 The Research Foundation Of State University Of New York Method of treating sepsis-induced ARDS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908838A (en) * 1998-02-19 1999-06-01 Medics Pharmaceutical Corporation Method for the treatment of acne
US6015803A (en) * 1998-05-04 2000-01-18 Wirostko; Emil Antibiotic treatment of age-related macular degeneration
WO1999058131A1 (en) * 1998-05-08 1999-11-18 University Of Miami Use of tetracyclines for treating meibomian gland disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Freinkel, et al. new England Journal of Medicine. Vol.273(16): 850-854. 1965. *

Also Published As

Publication number Publication date
NZ534613A (en) 2007-07-27
JP2005523313A (ja) 2005-08-04
KR20050005444A (ko) 2005-01-13
AU2003230935A1 (en) 2003-11-03
EP2368557A1 (en) 2011-09-28
WO2003088906A3 (en) 2004-02-26
US20030229055A1 (en) 2003-12-11
WO2003088906A2 (en) 2003-10-30
EP1494681A2 (en) 2005-01-12
US7008631B2 (en) 2006-03-07
CA2476792A1 (en) 2003-10-30
EP1494681A4 (en) 2008-08-06

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired