AU2003230935B2 - Methods of simultaneously treating ocular rosacea and acne rosacea - Google Patents

Methods of simultaneously treating ocular rosacea and acne rosacea Download PDF

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Publication number
AU2003230935B2
AU2003230935B2 AU2003230935A AU2003230935A AU2003230935B2 AU 2003230935 B2 AU2003230935 B2 AU 2003230935B2 AU 2003230935 A AU2003230935 A AU 2003230935A AU 2003230935 A AU2003230935 A AU 2003230935A AU 2003230935 B2 AU2003230935 B2 AU 2003230935B2
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AU
Australia
Prior art keywords
hydrogen
amino
halogen
dimethylamino
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003230935A
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English (en)
Other versions
AU2003230935A1 (en
Inventor
Robert A. Ashley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Collagenex Pharmaceuticals Inc
Original Assignee
Collagenex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Collagenex Pharmaceuticals Inc filed Critical Collagenex Pharmaceuticals Inc
Publication of AU2003230935A1 publication Critical patent/AU2003230935A1/en
Application granted granted Critical
Publication of AU2003230935B2 publication Critical patent/AU2003230935B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003230935A 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea Ceased AU2003230935B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37314102P 2002-04-16 2002-04-16
US60/373,141 2002-04-16
PCT/US2003/011686 WO2003088906A2 (en) 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea

Publications (2)

Publication Number Publication Date
AU2003230935A1 AU2003230935A1 (en) 2003-11-03
AU2003230935B2 true AU2003230935B2 (en) 2008-08-07

Family

ID=29250974

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003230935A Ceased AU2003230935B2 (en) 2002-04-16 2003-04-16 Methods of simultaneously treating ocular rosacea and acne rosacea

Country Status (8)

Country Link
US (1) US7008631B2 (https=)
EP (2) EP1494681A4 (https=)
JP (1) JP2005523313A (https=)
KR (1) KR20050005444A (https=)
AU (1) AU2003230935B2 (https=)
CA (1) CA2476792A1 (https=)
NZ (1) NZ534613A (https=)
WO (1) WO2003088906A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7211267B2 (en) * 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
EP2311440A1 (en) * 2001-04-05 2011-04-20 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US8192749B2 (en) * 2003-04-16 2012-06-05 Galderma Laboratories Inc. Methods of simultaneously treating ocular rosacea and acne rosacea
WO2004091483A2 (en) 2003-04-07 2004-10-28 Shire Laboratories, Inc. Once daily formulations of tetracyclines
AU2004261143B2 (en) * 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
AU2005222937B2 (en) * 2004-03-12 2010-06-17 Collagenex Pharmaceuticals, Inc. Method for treating aortic stenosis with non-antibacterial tetracycline formulations
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
CA2892739A1 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
WO2008079339A2 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
CN101668511A (zh) * 2007-02-28 2010-03-10 阿西克斯医疗公司 正常化睑板腺分泌的方法和化合物
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
WO2008121107A1 (en) * 2007-04-02 2008-10-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080305186A1 (en) * 2007-06-11 2008-12-11 Board Of Regents, The University Of Texas System Method and Composition for the Treatment of Cardiac Hypertrophy
WO2010017310A1 (en) 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US8107283B2 (en) * 2009-01-12 2012-01-31 Macronix International Co., Ltd. Method for setting PCRAM devices
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
AU2013214693B2 (en) * 2012-02-02 2017-02-23 Kenneth Gek-Jin OOI Improvements in tear film stability
FR3000396A1 (fr) * 2012-12-31 2014-07-04 Galderma Res & Dev Combinaison de laropiprant et de doxycycline pour le traitement de la rosacee
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
FR3026010B1 (fr) * 2014-09-18 2016-11-04 Galderma Sa Compositions comprenant un compose de la famille des avermectines et de la doxycycline pour le traitement de la rosacee
FR3064482B1 (fr) * 2017-04-03 2020-11-13 Horus Pharma Composition topique de doxycycline
JP7561029B2 (ja) 2018-01-07 2024-10-03 ドクター レディズ ラボラトリーズ リミテッド 炎症性皮膚状態を処置するためのミノサイクリン
EP3852734A1 (en) * 2018-09-22 2021-07-28 Novaliq GmbH Ophthalmic compositions for treatment of ocular surface damage and symptoms of dryness
CN111499545B (zh) * 2020-04-27 2022-05-03 武汉英纳氏药业有限公司 一种对氨基取代苯酚类化合物的制备方法
EP4551552A1 (en) * 2022-07-08 2025-05-14 ICM (Institut du Cerveau et de la Moelle Épinière) Tetracycline derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908838A (en) * 1998-02-19 1999-06-01 Medics Pharmaceutical Corporation Method for the treatment of acne
WO1999058131A1 (en) * 1998-05-08 1999-11-18 University Of Miami Use of tetracyclines for treating meibomian gland disease
US6015803A (en) * 1998-05-04 2000-01-18 Wirostko; Emil Antibiotic treatment of age-related macular degeneration

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957918A (en) * 1988-06-09 1990-09-18 Leonard Bloom Topical treatment of blepharitis
US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
US6071541A (en) * 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US6432934B1 (en) 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
US6384081B2 (en) 1998-10-09 2002-05-07 Charles L. Berman Treatment of diseases of the eye characterized by the formation of metalloproteinase
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
US6495158B1 (en) * 2001-01-19 2002-12-17 Lec Tec Corporation Acne patch
EP1383508B1 (en) * 2001-04-05 2006-06-21 Collagenex Pharmaceuticals, Inc. Doxycycline for the treatment of acne
US20040092491A1 (en) 2002-11-09 2004-05-13 The Research Foundation Of State University Of New York Method of treating sepsis-induced ARDS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908838A (en) * 1998-02-19 1999-06-01 Medics Pharmaceutical Corporation Method for the treatment of acne
US6015803A (en) * 1998-05-04 2000-01-18 Wirostko; Emil Antibiotic treatment of age-related macular degeneration
WO1999058131A1 (en) * 1998-05-08 1999-11-18 University Of Miami Use of tetracyclines for treating meibomian gland disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Freinkel, et al. new England Journal of Medicine. Vol.273(16): 850-854. 1965. *

Also Published As

Publication number Publication date
EP2368557A1 (en) 2011-09-28
EP1494681A2 (en) 2005-01-12
EP1494681A4 (en) 2008-08-06
US7008631B2 (en) 2006-03-07
KR20050005444A (ko) 2005-01-13
WO2003088906A2 (en) 2003-10-30
JP2005523313A (ja) 2005-08-04
CA2476792A1 (en) 2003-10-30
US20030229055A1 (en) 2003-12-11
WO2003088906A3 (en) 2004-02-26
NZ534613A (en) 2007-07-27
AU2003230935A1 (en) 2003-11-03

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired