AU2003222690A1 - Dual condensation/epimerization domain in non-ribosomal peptide synthetase systems - Google Patents

Dual condensation/epimerization domain in non-ribosomal peptide synthetase systems

Info

Publication number
AU2003222690A1
AU2003222690A1 AU2003222690A AU2003222690A AU2003222690A1 AU 2003222690 A1 AU2003222690 A1 AU 2003222690A1 AU 2003222690 A AU2003222690 A AU 2003222690A AU 2003222690 A AU2003222690 A AU 2003222690A AU 2003222690 A1 AU2003222690 A1 AU 2003222690A1
Authority
AU
Australia
Prior art keywords
peptide synthetase
ribosomal peptide
dual condensation
epimerization domain
synthetase systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003222690A
Inventor
Chris M. Farnet
Alfredo Staffa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thallion Pharmaceuticals Inc
Original Assignee
Ecopia Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecopia Biosciences Inc filed Critical Ecopia Biosciences Inc
Publication of AU2003222690A1 publication Critical patent/AU2003222690A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003222690A 2002-04-17 2003-04-17 Dual condensation/epimerization domain in non-ribosomal peptide synthetase systems Abandoned AU2003222690A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37279002P 2002-04-17 2002-04-17
US60/372,790 2002-04-17
PCT/CA2003/000575 WO2003089641A2 (en) 2002-04-17 2003-04-17 Dual condensation/epimerization domain in non-ribosomal peptide synthetase systems

Publications (1)

Publication Number Publication Date
AU2003222690A1 true AU2003222690A1 (en) 2003-11-03

Family

ID=27805336

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003222690A Abandoned AU2003222690A1 (en) 2002-04-17 2003-04-17 Dual condensation/epimerization domain in non-ribosomal peptide synthetase systems

Country Status (3)

Country Link
AU (1) AU2003222690A1 (en)
CA (1) CA2430580A1 (en)
WO (1) WO2003089641A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60109952T2 (en) * 2000-10-13 2006-02-09 Ecopia Biosciences Inc., Saint-Laurent RAMOPLANINBIOSYNTHESEGENKLUSTER
CN114657155B (en) * 2021-12-23 2024-01-19 中国农业科学院生物技术研究所 Novel non-ribosomal polypeptide synthetase resolution expression method
CN117384924B (en) * 2023-12-11 2024-06-25 中国农业科学院生物技术研究所 Polypeptide biosynthesis method based on enzyme domain resolution

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA801629B (en) * 1979-04-07 1981-03-25 Lepetit Spa Antibiotic a/16686 and process for the preparation thereof

Also Published As

Publication number Publication date
WO2003089641A3 (en) 2004-06-10
WO2003089641A2 (en) 2003-10-30
CA2430580A1 (en) 2003-09-04

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase