AU2003219592A1 - Chiral intermediate and process for the production thereof - Google Patents
Chiral intermediate and process for the production thereofInfo
- Publication number
- AU2003219592A1 AU2003219592A1 AU2003219592A AU2003219592A AU2003219592A1 AU 2003219592 A1 AU2003219592 A1 AU 2003219592A1 AU 2003219592 A AU2003219592 A AU 2003219592A AU 2003219592 A AU2003219592 A AU 2003219592A AU 2003219592 A1 AU2003219592 A1 AU 2003219592A1
- Authority
- AU
- Australia
- Prior art keywords
- production
- chiral intermediate
- chiral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0019340 | 2002-04-09 | ||
KR10-2002-0019340A KR100511533B1 (en) | 2002-04-09 | 2002-04-09 | CHIRAL INTERMEDIATE, PROCESS FOR THE PRODUCTION THEREOF, AND PROCESS FOR THE PRODUCTION OF HMG-CoA REDUCTASE INHIBITOR |
PCT/KR2003/000707 WO2003087112A1 (en) | 2002-04-09 | 2003-04-09 | Chiral intermediate and process for the production thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2003219592A1 true AU2003219592A1 (en) | 2003-10-27 |
Family
ID=29244717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003219592A Abandoned AU2003219592A1 (en) | 2002-04-09 | 2003-04-09 | Chiral intermediate and process for the production thereof |
Country Status (3)
Country | Link |
---|---|
KR (1) | KR100511533B1 (en) |
AU (1) | AU2003219592A1 (en) |
WO (1) | WO2003087112A1 (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
NL1015744C2 (en) | 2000-07-19 | 2002-01-22 | Dsm Nv | Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) acetic acid derivatives. |
BR0211072A (en) | 2001-07-13 | 2004-12-14 | Astrazeneca Uk Ltd | Process for preparing a compound, compound, and method for preparing a compound |
GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
PT1578731E (en) | 2002-12-16 | 2010-01-12 | Astrazeneca Uk Ltd | Process for the preparation of pyrimidine compounds |
GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
CA2537271A1 (en) | 2003-08-28 | 2005-03-17 | Teva Pharmaceutical Industries, Ltd. | Process for preparation of rosuvastatin calcium |
UY28501A1 (en) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | CHEMICAL COMPOUNDS |
GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
EP1601658A1 (en) | 2003-11-24 | 2005-12-07 | Teva Pharmaceutical Industries Limited | Crystalline ammonium salts of rosuvastatin |
US7244844B2 (en) | 2003-12-02 | 2007-07-17 | Teva Pharmaceutical Industries Ltd. | Reference standard for characterization of rosuvastatin |
WO2005054207A1 (en) * | 2003-12-04 | 2005-06-16 | Glenmark Pharmaceuticals Limited | Process for the preparation of pyrimidine derivatives |
US7851624B2 (en) | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
EP1673351A1 (en) | 2004-07-13 | 2006-06-28 | Teva Pharmaceutical Industries Ltd. | A process for the preparation of rosuvastatin involving a tempo-mediated oxidation step |
GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
KR101020024B1 (en) | 2005-02-22 | 2011-03-09 | 테바 파마슈티컬 인더스트리즈 리미티드 | Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof |
US20070037979A1 (en) * | 2005-02-22 | 2007-02-15 | Valerie Niddam-Hildesheim | Preparation of rosuvastatin |
KR100686186B1 (en) * | 2005-06-13 | 2007-02-26 | 영진종합건설 주식회사 | Structure for drainage in bridge |
BRPI0605917A2 (en) * | 2005-08-16 | 2009-05-26 | Teva Pharma | rosuvastatin crystalline intermediate |
CA2624801A1 (en) * | 2005-10-03 | 2007-04-12 | Teva Pharmaceutical Industries Ltd. | Diastereomeric purification of rosuvastatin |
JP2008521836A (en) * | 2005-10-04 | 2008-06-26 | テバ ファーマシューティカル インダストリーズ リミティド | Preparation of rosuvastatin |
PL2172471T3 (en) | 2007-04-18 | 2013-08-30 | Teva Pharma | A process for preparing intermediates of HMG-CoA reductase inhibitors |
JP2010501643A (en) * | 2007-07-12 | 2010-01-21 | テバ ファーマシューティカル インダストリーズ リミティド | Purification of rosuvastatin intermediate by thin film evaporation and chemical methods |
CA2696381A1 (en) | 2007-08-28 | 2009-03-05 | Ratiopharm Gmbh | Process for preparing pentanoic diacid derivatives |
US8653265B2 (en) | 2008-05-27 | 2014-02-18 | Changzhou Pharmaceutical Factory | Preparation method of rosuvastatin calcium and its intermediates |
KR101160152B1 (en) * | 2009-02-24 | 2012-06-27 | 한미사이언스 주식회사 | Novel process for preparing statin compound or its salt and intermediate used therein |
KR101157314B1 (en) * | 2009-06-05 | 2012-06-15 | 주식회사종근당 | New preparation of Rosuvastatin, the useful intermediates thereof and preparation of the same |
WO2011106546A1 (en) | 2010-02-25 | 2011-09-01 | Teva Pharmaceutical Industries Ltd. | A process for the preparation of rosuvastatin intermediate |
ITMI20100753A1 (en) * | 2010-04-30 | 2011-10-31 | Dipharma Francis Srl | PROCEDURE FOR THE PREPARATION OF STATINES |
ITMI20110397A1 (en) * | 2011-03-14 | 2012-09-15 | Dipharma Francis Srl | PROCEDURE FOR THE PREPARATION OF PYAVASTATIN AND ANALOGUES |
EP2383260A3 (en) * | 2010-04-30 | 2011-12-28 | Dipharma Francis S.r.l. | Process for the preparation of statins |
WO2011141934A1 (en) | 2010-05-13 | 2011-11-17 | Matrix Laboratories Ltd. | An improved process for the preparation of an intermediate of hmg-coa reductase inhibitors |
CN102212081B (en) * | 2010-12-30 | 2013-11-13 | 华润双鹤药业股份有限公司 | Preparation method of chiral intermediate product for synthesis of statins |
CN102584717B (en) * | 2011-01-17 | 2014-12-10 | 浙江九洲药业股份有限公司 | Intermediate for preparing rosuvastatin and preparation method and application thereof |
CN102816114B (en) * | 2011-06-09 | 2014-01-29 | 上海京新生物医药有限公司 | Preparation method of HMG-CoA reductase inhibitor |
AU2012345473B2 (en) | 2011-11-28 | 2017-05-25 | Mylan Laboratories Ltd | Process for producing chiral statin side chain intermediates employing candida|antarctica lipase B |
ITVI20130039A1 (en) * | 2013-02-20 | 2014-08-21 | F I S Fabbrica Italiana Sint I S P A | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR STATIN SYNTHESIS |
KR101710976B1 (en) * | 2015-04-08 | 2017-02-28 | 임광민 | Method for preparing of chiral intermediate and method for the preparing of HMG-CoA reductase inhibitor using chiral intermadiate |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4804770A (en) * | 1988-04-29 | 1989-02-14 | E. R. Squibb & Sons, Inc. | Process for preparing a keto-phosphonate intermediate useful in preparing HMG-CoA reductase inhibitors |
ES2110499T3 (en) * | 1991-06-19 | 1998-02-16 | Shionogi & Co | OPTICALLY ACTIVE INTERMEDIARY AND ITS PRODUCTION. |
JP3149265B2 (en) * | 1992-05-12 | 2001-03-26 | 鐘淵化学工業株式会社 | Method for producing optically active 3,5-dihydroxy fatty acid ester derivative |
JPH06107673A (en) * | 1992-08-12 | 1994-04-19 | Nissan Chem Ind Ltd | New 3-hydroxy-5-hexanoic acid derivative |
-
2002
- 2002-04-09 KR KR10-2002-0019340A patent/KR100511533B1/en not_active IP Right Cessation
-
2003
- 2003-04-09 AU AU2003219592A patent/AU2003219592A1/en not_active Abandoned
- 2003-04-09 WO PCT/KR2003/000707 patent/WO2003087112A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20030080620A (en) | 2003-10-17 |
KR100511533B1 (en) | 2005-08-31 |
WO2003087112A1 (en) | 2003-10-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |