AU2003212708A1 - Baculovirus expression system - Google Patents

Baculovirus expression system

Info

Publication number
AU2003212708A1
AU2003212708A1 AU2003212708A AU2003212708A AU2003212708A1 AU 2003212708 A1 AU2003212708 A1 AU 2003212708A1 AU 2003212708 A AU2003212708 A AU 2003212708A AU 2003212708 A AU2003212708 A AU 2003212708A AU 2003212708 A1 AU2003212708 A1 AU 2003212708A1
Authority
AU
Australia
Prior art keywords
expression system
baculovirus expression
baculovirus
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003212708A
Inventor
Gorben Peter Pijlman
Justinus Maria Vlak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stichting voor de Technische Wetenschappen STW
Original Assignee
Stichting voor de Technische Wetenschappen STW
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting voor de Technische Wetenschappen STW filed Critical Stichting voor de Technische Wetenschappen STW
Publication of AU2003212708A1 publication Critical patent/AU2003212708A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
AU2003212708A 2002-03-05 2003-03-05 Baculovirus expression system Abandoned AU2003212708A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL02075856.1 2002-03-05
EP02075856 2002-03-05
PCT/NL2003/000166 WO2003074714A1 (en) 2002-03-05 2003-03-05 Baculovirus expression system

Publications (1)

Publication Number Publication Date
AU2003212708A1 true AU2003212708A1 (en) 2003-09-16

Family

ID=27771891

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003212708A Abandoned AU2003212708A1 (en) 2002-03-05 2003-03-05 Baculovirus expression system

Country Status (2)

Country Link
AU (1) AU2003212708A1 (en)
WO (1) WO2003074714A1 (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007046703A2 (en) 2005-10-20 2007-04-26 Amsterdam Molecular Therapeutics B.V. Improved aav vectors produced in insect cells
ES2785223T3 (en) 2006-06-21 2020-10-06 Uniqure Ip Bv Insect cells for AAV vector production
DK2173888T3 (en) 2007-07-26 2016-11-28 Uniqure Ip Bv Baculovirus vectors comprising repeating coding sequences WITH differential preferred codons
GB0820631D0 (en) * 2008-11-11 2008-12-17 London School Hygiene & Tropical Medicine Vectors
EP2412387B1 (en) 2009-03-27 2014-11-19 Proyecto de Biomedicina Cima, S.L. Methods and compositions for the treatment of cirrhosis and liver fibrosis
EP2545165B1 (en) 2010-03-11 2020-07-29 uniQure IP B.V. Mutated rep encoding sequences for use in aav production
WO2011112090A2 (en) 2010-03-11 2011-09-15 Amsterdam Molecular Therapeutics (Amt) Ip B.V. Method for identifying variant rep protein encoding nucleic acids
WO2011122950A1 (en) 2010-04-01 2011-10-06 Amsterdam Molecular Therapeutics (Amt) Ip B.V. Monomeric duplex aav vectors
PT2744895E (en) 2011-09-08 2016-02-08 Uniqure Ip Bv Removal of contaminating viruses from aav preparations
US11246947B2 (en) 2013-08-05 2022-02-15 Academisch Ziekenhuis Leiden H.O.D. N. Leids Universitair Medisch Centrum Recombinant AAV-crumbs homologue composition and methods for treating LCA-8 and progressive RP
JP6735672B2 (en) 2013-09-12 2020-08-05 バイオマリン ファーマシューティカル インコーポレイテッド Adeno-associated virus factor VIII vector
EP3117005A1 (en) 2014-03-10 2017-01-18 UniQure IP B.V. Further improved aav vectors produced in insect cells
AU2016326602A1 (en) 2015-09-24 2018-03-29 Biomarin Pharmaceutical Inc. Adeno-associated virus factor VIII vectors, associated viral particles and therapeutic formulations comprising the same
WO2017083776A1 (en) 2015-11-12 2017-05-18 Research Institute At Nationwide Children's Hospital Methods of treating muscular dystrophy
KR20230156167A (en) 2016-04-16 2023-11-13 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 Methods of enhancing biological potency of baculovirus system-produced recombinant adeno-associated virus
WO2018022608A2 (en) 2016-07-26 2018-02-01 Biomarin Pharmaceutical Inc. Novel adeno-associated virus capsid proteins
EP3655538A1 (en) 2017-07-20 2020-05-27 uniQure IP B.V. Improved aav capsid production in insect cells
WO2019067982A2 (en) 2017-09-29 2019-04-04 Massachusetts Eye And Ear Infirmary Production of adeno-associated viruses in insect cells
AU2018394287A1 (en) 2017-12-29 2020-06-18 Uniqure Ip B.V. Modified viral vectors and methods of making and using the same
WO2019217513A2 (en) 2018-05-09 2019-11-14 Biomarin Pharmaceutical Inc. Methods of treating phenylketonuria
TW202005978A (en) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 Novel liver targeting adeno-associated viral vectors
KR20210008491A (en) 2018-05-14 2021-01-22 바이오마린 파머수티컬 인크. Stable expression of AAV vectors in juvenile subjects
CN109182380B (en) * 2018-08-14 2022-06-03 浙江大学 Preparation method and application of baculovirus-expressed classical swine fever E2 subunit vaccine
US20220098614A1 (en) 2019-02-28 2022-03-31 Benitec IP Holdings Inc. Compositions and Methods for Treating Oculopharyngeal Muscular Dystrophy (OPMD)
EP3969061A1 (en) 2019-05-14 2022-03-23 BioMarin Pharmaceutical Inc. Methods of redosing gene therapy vectors
BR112021026356A2 (en) * 2019-06-26 2022-04-12 Virovek Inc Baculovirus expression system
CN114729333A (en) 2019-09-27 2022-07-08 生物马林药物股份有限公司 Characterization of gene therapy viral particles using size exclusion chromatography and multi-angle light scattering techniques
TW202128733A (en) 2019-11-14 2021-08-01 美商拜奧馬林製藥公司 Treatment of hereditary angioedema with liver-specific gene therapy vectors
WO2021183895A1 (en) 2020-03-13 2021-09-16 Biomarin Pharmaceutical Inc. Treatment of fabry disease with aav gene therapy vectors
CA3169017A1 (en) 2020-04-02 2021-10-07 Uniqure Biopharma B.V. Novel cell line
CA3169087A1 (en) 2020-04-02 2021-10-07 David Johannes Francois DU PLESSIS Dual bifunctional vectors for aav production
AR122409A1 (en) 2020-04-03 2022-09-07 Biomarin Pharm Inc TREATMENT OF PHENYLKETONURIA WITH AAV AND THERAPEUTIC FORMULATIONS
WO2021236908A2 (en) 2020-05-20 2021-11-25 Biomarin Pharmaceutical Inc. Use of regulatory proteins for the production of adeno-associated virus
WO2022207899A1 (en) 2021-04-02 2022-10-06 Uniqure Biopharma B.V. Methods for producing single insect cell clones
EP4347798A2 (en) 2021-06-02 2024-04-10 uniQure biopharma B.V. Insect cell production of parvoviral vectors with modified capsid proteins
EP4347849A1 (en) 2021-06-02 2024-04-10 uniQure biopharma B.V. Adeno-associated virus vectors modified to bind high-density lipoprotein
CN117836010A (en) 2021-06-21 2024-04-05 优尼科生物制药有限公司 Improved cleavage procedure
CN113514440A (en) * 2021-07-01 2021-10-19 广州博徕斯生物科技股份有限公司 Baculovirus fluorescent nanoprobe
WO2023025920A1 (en) 2021-08-26 2023-03-02 Uniqure Biopharma B.V. Insect cell-produced high potency aav vectors with cns-tropism
AR127217A1 (en) 2021-10-01 2023-12-27 Biomarin Pharm Inc TREATMENT OF HEREDITARY ANGIOEDEMA WITH AAV GENOTHERAPY VECTORS AND THERAPEUTIC FORMULATIONS
WO2024064863A2 (en) 2022-09-22 2024-03-28 Biomarin Pharmaceutical Inc. Treatment of arrhythmogenic cardiomyopathy with aav gene therapy vectors
WO2024064856A1 (en) 2022-09-22 2024-03-28 Biomarin Pharmaceutical Inc. Treatment of cardiomyopathy with aav gene therapy vectors
CN115851574B (en) * 2022-12-27 2024-04-19 青岛农业大学 Beet armyworm cell line

Also Published As

Publication number Publication date
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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase