AU2002357660A1 - Treatment of infectious disease using interleukin-1 beta converting enzyme (ice)/ced-3 family inhibitors - Google Patents
Treatment of infectious disease using interleukin-1 beta converting enzyme (ice)/ced-3 family inhibitorsInfo
- Publication number
- AU2002357660A1 AU2002357660A1 AU2002357660A AU2002357660A AU2002357660A1 AU 2002357660 A1 AU2002357660 A1 AU 2002357660A1 AU 2002357660 A AU2002357660 A AU 2002357660A AU 2002357660 A AU2002357660 A AU 2002357660A AU 2002357660 A1 AU2002357660 A1 AU 2002357660A1
- Authority
- AU
- Australia
- Prior art keywords
- ced
- interleukin
- ice
- treatment
- infectious disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/124—Disinfecting agents, e.g. antimicrobials
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Birds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/982,123 | 2001-10-16 | ||
| US09/982,123 US6531467B2 (en) | 1996-09-12 | 2001-10-16 | Inhibition of inflammation using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
| US10/007,632 US6610683B2 (en) | 1996-09-12 | 2001-11-13 | Treatment of infectious disease using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
| US10/007,632 | 2001-11-13 | ||
| PCT/US2002/033157 WO2003032918A2 (en) | 2001-10-16 | 2002-10-16 | Treatment of infectious disease using interleukin-1 beta converting enzyme (ice)/ced-3 family inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002357660A1 true AU2002357660A1 (en) | 2003-04-28 |
Family
ID=26677222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002357660A Abandoned AU2002357660A1 (en) | 2001-10-16 | 2002-10-16 | Treatment of infectious disease using interleukin-1 beta converting enzyme (ice)/ced-3 family inhibitors |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6610683B2 (https=) |
| EP (1) | EP1443935A4 (https=) |
| JP (1) | JP2005506346A (https=) |
| AU (1) | AU2002357660A1 (https=) |
| CA (1) | CA2463729A1 (https=) |
| WO (1) | WO2003032918A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184244B1 (en) * | 1996-12-16 | 2001-02-06 | Idun Pharmaceuticals, Inc. | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| CA2534352A1 (en) * | 2003-08-08 | 2005-02-17 | Arriva Pharmaceuticals, Inc. | Methods of protein production in yeast |
| EP1672681B8 (en) * | 2003-10-08 | 2011-09-21 | Miyagi Nikon Precision Co., Ltd. | Exposure apparatus, substrate carrying method, exposure method, and method for producing device |
| JP2007511539A (ja) * | 2003-11-14 | 2007-05-10 | バクスター・インターナショナル・インコーポレイテッド | α1−抗トリプシン組成物およびこのような組成物を用いた処置方法 |
| CA2559062A1 (en) * | 2004-03-09 | 2005-09-22 | Arriva Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor |
| MXPA06013256A (es) | 2004-05-15 | 2007-02-08 | Vertex Pharma | Tratamiento de crisis convulsivas utilizando inhibidores ice. |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| CA2567080A1 (en) | 2004-05-27 | 2005-12-15 | Vertex Pharmaceuticals Incorporated | Ice inhibitors for the treatment of autoinflammatory diseases |
| US7384558B2 (en) * | 2004-07-26 | 2008-06-10 | Baxter International Inc. | Compositions capable of inhibiting reactive oxygen and carbonyl species |
| US20060073504A1 (en) * | 2004-09-20 | 2006-04-06 | The Regents Of The University Of California | Treatment of pain by inhibition of caspase signaling |
| US20070105768A1 (en) * | 2004-11-10 | 2007-05-10 | Rajiv Nayar | Dry recombinant human alpha 1-antitrypsin formulation |
| US8410149B2 (en) | 2004-12-06 | 2013-04-02 | Siga Technologies Inc. | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
| CA2590962A1 (en) * | 2004-12-06 | 2006-06-15 | Siga Technologies, Inc. | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
| US7994221B2 (en) | 2004-12-06 | 2011-08-09 | Siga Technologies, Inc. | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
| WO2008045017A2 (en) * | 2005-06-22 | 2008-04-17 | Diamond Scott L | Sars and ebola inhibitors and use thereof, and methods for their discovery |
| CN101034257B (zh) * | 2007-04-06 | 2010-09-08 | 上海复旦天臣新技术有限公司 | 用于全息记录的感光薄膜及其制备方法 |
| US9116157B2 (en) | 2010-11-05 | 2015-08-25 | Brandeis University | Ice-cleaved alpha-synuclein as a biomarker |
| CN103196739A (zh) * | 2013-04-10 | 2013-07-10 | 哈尔滨体育学院 | 一种优秀冰雪运动员肌细胞凋亡鉴定方法 |
| CN107029221A (zh) * | 2017-01-26 | 2017-08-11 | 上海交通大学 | 胱氨酸蛋白酶抑制剂在制备防治紫外光诱导的皮肤损伤药物、保健品及各种制剂中的应用 |
| KR20240132016A (ko) * | 2021-12-08 | 2024-09-02 | 사이토사이트 바이오파마 인코포레이티드 | 그랜자임 b에 특이적인 화합물 및 그의 용도 |
| KR20240116797A (ko) * | 2021-12-08 | 2024-07-30 | 사이토사이트 바이오파마 인코포레이티드 | 그랜자임 b에 특이적인 화합물에 대한 전구약물 및 그의 용도 |
| TW202508601A (zh) * | 2023-06-07 | 2025-03-01 | 美商塞托賽特生物製藥股份有限公司 | 對顆粒酶b具有特異性之化合物之前驅藥及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204261B1 (en) | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| WO1991015577A1 (en) | 1990-04-04 | 1991-10-17 | Black, Roy, A. | INTERLEUKIN 1'beta' PROTEASE |
| AU657701B2 (en) | 1991-08-30 | 1995-03-23 | Vertex Pharmaceuticals Incorporated | Interleukin 1beta protease and interleukin 1beta protease inhibitors |
| EP0547699A1 (en) | 1991-12-19 | 1993-06-23 | Merck & Co. Inc. | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme |
| US5514694A (en) * | 1992-09-21 | 1996-05-07 | Georgia Tech Research Corp | Peptidyl ketoamides |
| US5504080A (en) | 1992-10-28 | 1996-04-02 | Bristol-Myers Squibb Co. | Benzo-fused lactams |
| EP0706525A1 (en) | 1993-06-30 | 1996-04-17 | Novartis AG | Antihypertensive tricyclic azepine derivatives useful as inhibitors of enkephalinase and ace |
| KR20000036056A (ko) * | 1996-09-12 | 2000-06-26 | 아이디유엔 파마슈티칼즈, 인코포레이티드 | 인터루킨-1β 전환 효소 및 관련 프로테아제의 억제제로서의 C-말단 변형된 (N-치환된)-2-인돌릴 디펩티드 |
| NZ330451A (https=) * | 1996-09-12 | 2000-01-28 | Idun Pharmaceuticals Inc | |
| US5869519A (en) * | 1996-12-16 | 1999-02-09 | Idun Pharmaceuticals, Inc. | C-terminal modified (n-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| US5968927A (en) * | 1996-09-20 | 1999-10-19 | Idun Pharmaceuticals, Inc. | Tricyclic compounds for the inhibition of the ICE/ced-3 protease family of enzymes |
| US6184244B1 (en) * | 1996-12-16 | 2001-02-06 | Idun Pharmaceuticals, Inc. | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| FR2775594B1 (fr) * | 1998-03-06 | 2002-12-27 | Oreal | Utilisation d'un compose inhibant l'activite d'un canal sodium ou d'un canal calcium dans une composition a usage topique |
-
2001
- 2001-11-13 US US10/007,632 patent/US6610683B2/en not_active Expired - Lifetime
-
2002
- 2002-07-29 US US10/208,729 patent/US6693096B2/en not_active Expired - Lifetime
- 2002-10-16 AU AU2002357660A patent/AU2002357660A1/en not_active Abandoned
- 2002-10-16 EP EP02792195A patent/EP1443935A4/en not_active Withdrawn
- 2002-10-16 WO PCT/US2002/033157 patent/WO2003032918A2/en not_active Ceased
- 2002-10-16 CA CA002463729A patent/CA2463729A1/en not_active Abandoned
- 2002-10-16 JP JP2003535724A patent/JP2005506346A/ja active Pending
-
2003
- 2003-09-02 US US10/653,607 patent/US20040058850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005506346A (ja) | 2005-03-03 |
| EP1443935A4 (en) | 2007-11-07 |
| EP1443935A2 (en) | 2004-08-11 |
| US20020128306A1 (en) | 2002-09-12 |
| US20030186842A1 (en) | 2003-10-02 |
| US6693096B2 (en) | 2004-02-17 |
| WO2003032918A3 (en) | 2003-07-24 |
| WO2003032918A2 (en) | 2003-04-24 |
| US6610683B2 (en) | 2003-08-26 |
| CA2463729A1 (en) | 2003-04-24 |
| US20040058850A1 (en) | 2004-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |