AU2002352424A1 - Solution-phase process for the manufacture of decapeptide - Google Patents

Solution-phase process for the manufacture of decapeptide

Info

Publication number
AU2002352424A1
AU2002352424A1 AU2002352424A AU2002352424A AU2002352424A1 AU 2002352424 A1 AU2002352424 A1 AU 2002352424A1 AU 2002352424 A AU2002352424 A AU 2002352424A AU 2002352424 A AU2002352424 A AU 2002352424A AU 2002352424 A1 AU2002352424 A1 AU 2002352424A1
Authority
AU
Australia
Prior art keywords
decapeptide
manufacture
solution
phase process
phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002352424A
Inventor
Alan Charles Barker
Kevin William Leslie
Mohammed Pervez
William Eric Stanier
Nigel Philip Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2002352424A1 publication Critical patent/AU2002352424A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2002352424A 2001-12-19 2002-12-18 Solution-phase process for the manufacture of decapeptide Abandoned AU2002352424A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0130285.0 2001-12-19
GB0130285A GB0130285D0 (en) 2001-12-19 2001-12-19 Chemical process
PCT/GB2002/005741 WO2003051918A1 (en) 2001-12-19 2002-12-18 Solution-phase process for the manufacture of decapeptide

Publications (1)

Publication Number Publication Date
AU2002352424A1 true AU2002352424A1 (en) 2003-06-30

Family

ID=9927875

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002352424A Abandoned AU2002352424A1 (en) 2001-12-19 2002-12-18 Solution-phase process for the manufacture of decapeptide

Country Status (3)

Country Link
AU (1) AU2002352424A1 (en)
GB (1) GB0130285D0 (en)
WO (1) WO2003051918A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130286D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
BRPI0507971A (en) * 2004-02-23 2007-07-24 Tufts College compound, pharmaceutical composition, use of a compound, method to inhibit the proteolytic activity of a postproline cleavage enzyme and packaged medicine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1188646B (en) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica TRIPEPTIDE WITH IMMUNOSTIMULANT ACTIVITY
DD260084A1 (en) * 1987-04-20 1988-09-14 Univ Leipzig PROCESS FOR THE PRODUCTION OF PEPTIDES
GB9702377D0 (en) 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives
GB9809021D0 (en) 1998-04-29 1998-06-24 Zeneca Ltd Chemical process
GB0017979D0 (en) * 2000-07-22 2000-09-13 Astrazeneca Ab Chemical process

Also Published As

Publication number Publication date
WO2003051918A1 (en) 2003-06-26
GB0130285D0 (en) 2002-02-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase