AU2002326018A1 - Assay for identifying ion channel modulators - Google Patents

Assay for identifying ion channel modulators

Info

Publication number
AU2002326018A1
AU2002326018A1 AU2002326018A AU2002326018A AU2002326018A1 AU 2002326018 A1 AU2002326018 A1 AU 2002326018A1 AU 2002326018 A AU2002326018 A AU 2002326018A AU 2002326018 A AU2002326018 A AU 2002326018A AU 2002326018 A1 AU2002326018 A1 AU 2002326018A1
Authority
AU
Australia
Prior art keywords
assay
ion channel
channel modulators
identifying ion
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002326018A
Inventor
Stephen Antony Burbidge
Paula Green
David Thomas Grose
Martin Main
Helen Meadows
Jeff Pohl
Andrew Randall
Derek John Trezise
Jennings Franklin Worley Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Glaxo Group Ltd
Original Assignee
SmithKline Beecham Ltd
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, Glaxo Group Ltd filed Critical SmithKline Beecham Ltd
Publication of AU2002326018A1 publication Critical patent/AU2002326018A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2002326018A 2001-08-24 2002-08-27 Assay for identifying ion channel modulators Abandoned AU2002326018A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0120589A GB0120589D0 (en) 2001-08-24 2001-08-24 Assay
GB0120589.7 2001-08-24
PCT/GB2002/003927 WO2003019186A2 (en) 2001-08-24 2002-08-27 Assay for identifying ion channel modulators

Publications (1)

Publication Number Publication Date
AU2002326018A1 true AU2002326018A1 (en) 2003-03-10

Family

ID=9920914

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002326018A Abandoned AU2002326018A1 (en) 2001-08-24 2002-08-27 Assay for identifying ion channel modulators

Country Status (3)

Country Link
AU (1) AU2002326018A1 (en)
GB (1) GB0120589D0 (en)
WO (1) WO2003019186A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7442519B2 (en) 2002-06-25 2008-10-28 Serono Genetics Institute, S.A. KCNQ2-15 potassium channel
DE60316161T2 (en) * 2002-06-25 2008-06-19 Serono Genetics Institute S.A. NEW KCNQ POLYPEPTIDES AND THEIR USE IN THE DIAGNOSIS OF MENTAL DISEASES
WO2004060917A2 (en) * 2003-01-07 2004-07-22 Neuromed Technologies, Inc. Fluorescence based t-type channel assay
AU2004259199A1 (en) * 2003-07-15 2005-02-03 Chantest Corporation High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins
DE102006003177A1 (en) 2006-01-23 2007-08-02 Siemens Ag Apparatus and method for detecting an analyte

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702112D0 (en) * 1997-06-04 1997-06-04 Holdingbolaget Vid Goeteborgs Method and apparatus for detection of a receptor antagonist
GB9925799D0 (en) * 1999-11-02 1999-12-29 Cambridge Drug Discovery Ltd Ion channel permeability

Also Published As

Publication number Publication date
WO2003019186A2 (en) 2003-03-06
WO2003019186A3 (en) 2003-05-08
GB0120589D0 (en) 2001-10-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase