AU2002324424A1 - Human secreted proteins - Google Patents

Human secreted proteins

Info

Publication number
AU2002324424A1
AU2002324424A1 AU2002324424A AU2002324424A AU2002324424A1 AU 2002324424 A1 AU2002324424 A1 AU 2002324424A1 AU 2002324424 A AU2002324424 A AU 2002324424A AU 2002324424 A AU2002324424 A AU 2002324424A AU 2002324424 A1 AU2002324424 A1 AU 2002324424A1
Authority
AU
Australia
Prior art keywords
secreted proteins
human secreted
human
proteins
secreted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002324424A
Inventor
Craig A. Rosen
Steven M. Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of AU2002324424A1 publication Critical patent/AU2002324424A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU2002324424A 2001-03-21 2002-03-19 Human secreted proteins Abandoned AU2002324424A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US27734001P 2001-03-21 2001-03-21
US60/277,340 2001-03-21
US30617101P 2001-07-19 2001-07-19
US60/306,171 2001-07-19
US33128701P 2001-11-13 2001-11-13
US60/331,287 2001-11-13
PCT/US2002/009785 WO2002095010A2 (en) 2001-03-21 2002-03-19 Human secreted proteins

Publications (1)

Publication Number Publication Date
AU2002324424A1 true AU2002324424A1 (en) 2002-12-03

Family

ID=27402891

Family Applications (6)

Application Number Title Priority Date Filing Date
AU2002320013A Abandoned AU2002320013A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002332391A Abandoned AU2002332391A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002324424A Abandoned AU2002324424A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002354719A Abandoned AU2002354719A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002363296A Abandoned AU2002363296A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002326293A Abandoned AU2002326293A1 (en) 2001-03-21 2002-03-19 Human secreted proteins

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AU2002320013A Abandoned AU2002320013A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002332391A Abandoned AU2002332391A1 (en) 2001-03-21 2002-03-19 Human secreted proteins

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2002354719A Abandoned AU2002354719A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002363296A Abandoned AU2002363296A1 (en) 2001-03-21 2002-03-19 Human secreted proteins
AU2002326293A Abandoned AU2002326293A1 (en) 2001-03-21 2002-03-19 Human secreted proteins

Country Status (4)

Country Link
EP (7) EP1379264A4 (en)
AU (6) AU2002320013A1 (en)
CA (7) CA2441755A1 (en)
WO (7) WO2002090526A2 (en)

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US20060052321A1 (en) 2002-04-05 2006-03-09 Raitano Arthur B Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
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US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
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US7291719B2 (en) 2000-07-25 2007-11-06 Genentech, Inc. PRO4332 antibodies
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US20020111302A1 (en) * 2000-11-30 2002-08-15 Y. Tom Tang Novel nucleic acids and polypeptides
WO2002083921A2 (en) * 2001-04-10 2002-10-24 Agensys, Inc. Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
US7164007B2 (en) 2001-06-20 2007-01-16 Genentech, Inc. Anti-PR020044 antibodies
ES2537074T3 (en) 2001-09-06 2015-06-02 Agensys, Inc. Nucleic acid and corresponding protein called STEAP-1 useful in the treatment and detection of cancer
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
CA2463596A1 (en) 2001-10-12 2003-04-24 Yamanouchi Pharmaceutical Co., Ltd. Method of screening cell death inhibitor
CN103536916B (en) 2002-04-09 2016-08-17 比奥根Ma公司 For the method treating TWEAK associated conditions
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US7709610B2 (en) 2003-05-08 2010-05-04 Facet Biotech Corporation Therapeutic use of anti-CS1 antibodies
US20050025763A1 (en) 2003-05-08 2005-02-03 Protein Design Laboratories, Inc. Therapeutic use of anti-CS1 antibodies
WO2005019258A2 (en) * 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
EP1842920B2 (en) * 2003-09-23 2017-06-21 University Of North Carolina At Chapel Hill Cells coexpressing vitamin K reductase and vitamin K dependent protein and use thereof to improve the productivity of said vitamin K dependent protein
JP4777251B2 (en) * 2003-10-14 2011-09-21 バクスター・インターナショナル・インコーポレイテッド Therapeutic target of vitamin K epoxide reductase complex subunit 1VKORC1, coumarin and its derivatives
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US8759305B2 (en) * 2004-09-01 2014-06-24 Dynavax Technologies Corporation Methods and compositions for inhibition of innate immune responses and autoimmunity
JP2008512100A (en) * 2004-09-07 2008-04-24 テレソン インスティテュート フォー チャイルド ヘルス リサーチ Method for diagnosis and / or prediction of onset of allergic diseases
US20100003241A1 (en) * 2004-09-07 2010-01-07 Patrick Holt Agents for treatment or prevention of an allergic disorder
EP1859277A4 (en) 2005-02-17 2010-03-17 Biogen Idec Inc Treating neurological disorders
DK1853700T3 (en) 2005-02-28 2013-01-07 Baxter Int RECOMBINANT CO-EXPRESSION OF VITAMIN-K-EPOXID REDUCTASE UNIT 1 TO IMPROVE VITAMIN-K-DEPENDED PROTEIN EXPRESSION
CA2601574C (en) 2005-03-15 2014-12-02 University Of North Carolina At Chapel Hill Methods and compositions for producing active vitamin k-dependent proteins
CA2607697C (en) 2005-05-10 2015-01-06 Biogen Idec Ma Inc. Treating and evaluating inflammatory disorders
WO2006138219A2 (en) 2005-06-13 2006-12-28 Biogen Idec Ma Inc. Methods of diagnosis / prognosis of inflammatory conditions
WO2007025347A1 (en) * 2005-09-01 2007-03-08 Howard Florey Institute Of Experimental Physiology And Medicine Prophylactic and therapeutic agents and uses therefor
GB0521488D0 (en) * 2005-10-21 2005-11-30 Ares Trading Sa Integral membrane protein
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
PT2502938E (en) 2006-10-27 2015-06-05 Genentech Inc Antibodies and immunoconjugates and uses therefor
CN101636179B (en) 2006-11-07 2012-10-10 默沙东公司 Antagonists of pcsk9
US8093222B2 (en) 2006-11-27 2012-01-10 Isis Pharmaceuticals, Inc. Methods for treating hypercholesterolemia
CA2680832A1 (en) 2007-03-27 2008-10-02 Merck & Co., Inc. Method for detecting autoprocessed, secreted pcsk9
JOP20080381B1 (en) 2007-08-23 2023-03-28 Amgen Inc Antigen Binding Proteins to Proprotein Convertase subtillisin Kexin type 9 (pcsk9)
AU2008317261B2 (en) 2007-10-26 2015-04-09 Dynavax Technologies Corporation Methods and compositions for inhibition of immune responses and autoimmunity
WO2009070350A1 (en) * 2007-11-30 2009-06-04 Siemens Healthcare Diagnostics Inc. Adiponectin receptor fragments and methods of use
AR070315A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc ANTIBODIES 1B20 ANTAGONISTS OF PCSK9
AR070316A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc PCSK9 ANTAGONISTS (SUBTILISINE-KEXINA TYPE 9 PROPROTEIN)
WO2010068526A1 (en) 2008-12-12 2010-06-17 Merck Sharp & Dohme Corp. Pcsk9 immunoassay
CN102639150A (en) 2009-10-30 2012-08-15 默沙东公司 AX213 and AX132 PCSK9 antagonists and variants
EP2493505A4 (en) 2009-10-30 2013-06-12 Merck Sharp & Dohme Ax1 and ax189 pcsk9 antagonists and variants
KR101810593B1 (en) 2010-06-16 2017-12-22 다이나박스 테크놀로지 코퍼레이션 Methods of treatment using tlr7 and/or tlr9 inhibitors
US8871737B2 (en) 2010-09-22 2014-10-28 Alios Biopharma, Inc. Substituted nucleotide analogs
US9631002B2 (en) 2010-12-21 2017-04-25 The University Of North Carolina At Chapel Hill Methods and compositions for producing active vitamin K-dependent proteins
WO2013096680A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
EP2828277A1 (en) 2012-03-21 2015-01-28 Vertex Pharmaceuticals Incorporated Solid forms of a thiophosphoramidate nucleotide prodrug
WO2013142157A1 (en) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
US9034332B1 (en) 2014-07-15 2015-05-19 Kymab Limited Precision medicine by targeting rare human PCSK9 variants for cholesterol treatment
US8986691B1 (en) 2014-07-15 2015-03-24 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US9914769B2 (en) 2014-07-15 2018-03-13 Kymab Limited Precision medicine for cholesterol treatment
US8980273B1 (en) 2014-07-15 2015-03-17 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9023359B1 (en) 2014-07-15 2015-05-05 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8883157B1 (en) 2013-12-17 2014-11-11 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8945560B1 (en) 2014-07-15 2015-02-03 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US9045548B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision Medicine by targeting rare human PCSK9 variants for cholesterol treatment
US9045545B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision medicine by targeting PD-L1 variants for treatment of cancer
US8986694B1 (en) 2014-07-15 2015-03-24 Kymab Limited Targeting human nav1.7 variants for treatment of pain
US9067998B1 (en) 2014-07-15 2015-06-30 Kymab Limited Targeting PD-1 variants for treatment of cancer
US9051378B1 (en) 2014-07-15 2015-06-09 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8992927B1 (en) 2014-07-15 2015-03-31 Kymab Limited Targeting human NAV1.7 variants for treatment of pain
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US9150660B1 (en) 2014-07-15 2015-10-06 Kymab Limited Precision Medicine by targeting human NAV1.8 variants for treatment of pain
US9139648B1 (en) 2014-07-15 2015-09-22 Kymab Limited Precision medicine by targeting human NAV1.9 variants for treatment of pain
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
GB2605925B (en) 2016-12-23 2023-02-22 Harvard College Gene editing of PCSK9
ES2955852T3 (en) 2017-04-03 2023-12-07 Hoffmann La Roche STEAP-1 binding antibodies
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EP1097199A4 (en) * 1998-07-15 2005-02-23 Human Genome Sciences Inc 71 human secreted proteins

Also Published As

Publication number Publication date
EP1414845A4 (en) 2009-07-08
AU2002320013A1 (en) 2002-11-18
EP1379132A2 (en) 2004-01-14
EP1404702A4 (en) 2009-07-08
AU2002363296A1 (en) 2003-05-12
WO2002076488A1 (en) 2002-10-03
CA2441416A1 (en) 2003-01-16
EP1423134A2 (en) 2004-06-02
EP1390390A2 (en) 2004-02-25
CA2441755A1 (en) 2003-05-08
CA2441840A1 (en) 2002-11-28
EP1390390A4 (en) 2009-07-08
WO2003038063A2 (en) 2003-05-08
CA2441417A1 (en) 2002-11-14
WO2002095010A2 (en) 2002-11-28
AU2002332391A1 (en) 2003-01-02
WO2002102994A3 (en) 2003-07-24
CA2441832A1 (en) 2002-12-27
WO2002102993A3 (en) 2004-03-25
AU2002354719A1 (en) 2003-01-21
AU2002326293A1 (en) 2003-01-02
WO2003004622A3 (en) 2004-02-19
EP1414845A2 (en) 2004-05-06
EP1404702A2 (en) 2004-04-07
WO2002102993A2 (en) 2002-12-27
CA2441702A1 (en) 2002-12-27
WO2002090526A3 (en) 2003-10-30
EP1379264A4 (en) 2009-07-08
CA2441397A1 (en) 2002-10-03
WO2002102994A2 (en) 2002-12-27
WO2002095010A3 (en) 2004-02-12
EP1379264A1 (en) 2004-01-14
WO2003004622A2 (en) 2003-01-16
EP1381622A2 (en) 2004-01-21
WO2002090526A2 (en) 2002-11-14
EP1379132A4 (en) 2009-07-01
WO2003038063A3 (en) 2003-12-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase