AU2002324120A1 - Tricyclic pyridin-2-one analogues as ligands for gaba-a receptors - Google Patents

Tricyclic pyridin-2-one analogues as ligands for gaba-a receptors

Info

Publication number
AU2002324120A1
AU2002324120A1 AU2002324120A AU2002324120A AU2002324120A1 AU 2002324120 A1 AU2002324120 A1 AU 2002324120A1 AU 2002324120 A AU2002324120 A AU 2002324120A AU 2002324120 A AU2002324120 A AU 2002324120A AU 2002324120 A1 AU2002324120 A1 AU 2002324120A1
Authority
AU
Australia
Prior art keywords
gaba
tricyclic
pyridin
analogues
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002324120A
Inventor
Sylvie Bourrain
Simon Charles Goodacre
David James Hallett
Richard Thomas Lewis
Michael Rowley
Francine Sternfeld
Leslie Joseph Street
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU2002324120A1 publication Critical patent/AU2002324120A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2002324120A 2001-08-21 2002-08-12 Tricyclic pyridin-2-one analogues as ligands for gaba-a receptors Abandoned AU2002324120A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0120345.4 2001-08-21
GBGB0120345.4A GB0120345D0 (en) 2001-08-21 2001-08-21 Therapeutic agents
PCT/GB2002/003703 WO2003018546A2 (en) 2001-08-21 2002-08-12 Tricyclic pyridin-2-one analogues as ligands for gaba-a receptors

Publications (1)

Publication Number Publication Date
AU2002324120A1 true AU2002324120A1 (en) 2003-03-10

Family

ID=9920763

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002324120A Abandoned AU2002324120A1 (en) 2001-08-21 2002-08-12 Tricyclic pyridin-2-one analogues as ligands for gaba-a receptors

Country Status (3)

Country Link
AU (1) AU2002324120A1 (en)
GB (1) GB0120345D0 (en)
WO (1) WO2003018546A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080080206A (en) 2005-12-20 2008-09-02 아스트라제네카 아베 Substituted cinnoline derivatives as gabaa-receptor modulators and method for their synthesis
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
CN103524470B (en) * 2013-10-15 2016-04-20 北京师范大学 The synthetic method of 2-amino-1-(the fluoro-2-chromanyl of-6-) ethanol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2719843B1 (en) * 1994-05-10 1996-06-07 Synthelabo Derivatives of 5,6-dihydro-4h-imidazo [2 ', 1': 2,3] imidazo- [4,5,1-ij] quinoline and 4,5-dihydroimidazo [1,2-a] pyrrolo- [1,2,3-cd] benzimidazole, their preparation and their therapeutic application.
GB9708945D0 (en) * 1997-05-01 1997-06-25 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
WO2003018546A2 (en) 2003-03-06
WO2003018546A3 (en) 2003-07-17
GB0120345D0 (en) 2001-10-17

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase