AU2002319296A1 - Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processes - Google Patents
Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with CGMP regulated processesInfo
- Publication number
- AU2002319296A1 AU2002319296A1 AU2002319296A AU2002319296A AU2002319296A1 AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1 AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A AU2002319296 A AU 2002319296A AU 2002319296 A1 AU2002319296 A1 AU 2002319296A1
- Authority
- AU
- Australia
- Prior art keywords
- alkoxyphenyl
- treatment
- diseases associated
- regulated processes
- substituted imidazotriazinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000010099 disease Diseases 0.000 title 1
- IJYHVZICHKCLMQ-UHFFFAOYSA-N imidazo[4,5-d]triazin-4-one Chemical class O=C1N=NN=C2N=CN=C12 IJYHVZICHKCLMQ-UHFFFAOYSA-N 0.000 title 1
- 230000001105 regulatory Effects 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10135815.6 | 2001-07-23 | ||
DE10135815A DE10135815A1 (en) | 2001-07-23 | 2001-07-23 | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
PCT/EP2002/007959 WO2003011262A2 (en) | 2001-07-23 | 2002-07-17 | Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cgmp regulated processes |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2002319296A1 true AU2002319296A1 (en) | 2003-05-29 |
AU2002319296B2 AU2002319296B2 (en) | 2007-08-30 |
Family
ID=7692784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002319296A Ceased AU2002319296B2 (en) | 2001-07-23 | 2002-07-17 | Use of 2-alkoxyphenyl-substituted imidazotriazinones for the treatment of diseases associated with cGMP regulated processes |
Country Status (28)
Country | Link |
---|---|
US (3) | US6930108B2 (en) |
EP (2) | EP1733728A3 (en) |
JP (1) | JP2005504751A (en) |
KR (1) | KR20040032865A (en) |
CN (1) | CN1649593A (en) |
AT (1) | ATE442144T1 (en) |
AU (1) | AU2002319296B2 (en) |
BG (1) | BG108533A (en) |
BR (1) | BR0211359A (en) |
CA (1) | CA2454414A1 (en) |
CO (1) | CO5560536A2 (en) |
CZ (1) | CZ2004128A3 (en) |
DE (2) | DE10135815A1 (en) |
EC (1) | ECSP044956A (en) |
EE (1) | EE200400056A (en) |
ES (1) | ES2330418T3 (en) |
HR (1) | HRP20040065A2 (en) |
HU (1) | HUP0500734A3 (en) |
IL (1) | IL159840A0 (en) |
MA (1) | MA26128A1 (en) |
MX (1) | MXPA04000675A (en) |
NO (1) | NO20040294L (en) |
NZ (1) | NZ530703A (en) |
PL (1) | PL373392A1 (en) |
RU (1) | RU2321406C9 (en) |
SK (1) | SK442004A3 (en) |
UA (1) | UA76997C2 (en) |
WO (1) | WO2003011262A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10135815A1 (en) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
JP2006219374A (en) * | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Imidazotriazinone derivative having pde 7 inhibition |
DE102004023069A1 (en) | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | New dosage forms of the PDE 5 inhibitor vardenafil |
DE102004038328A1 (en) * | 2004-08-06 | 2006-03-16 | Bayer Healthcare Ag | New uses of 2-phenyl-substituted imidazotriazinone derivatives |
CN101163476A (en) | 2005-04-19 | 2008-04-16 | 尼科梅德有限责任公司 | Roflumilast for the treatment of pulmonary hypertension |
US8648073B2 (en) | 2009-12-30 | 2014-02-11 | Fochon Pharma, Inc. | Certain dipeptidyl peptidase inhibitors |
AT512084A1 (en) * | 2011-10-20 | 2013-05-15 | Univ Wien Tech | DIAZABICYCLO AND DIAZASPIRO ALKAN DERIVATIVES AS PHOSPHODIESTERASE-5 INHIBITORS |
US20160317542A1 (en) | 2013-12-09 | 2016-11-03 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
JP7150721B2 (en) * | 2016-12-16 | 2022-10-11 | システィック・ファイブロシス・ファンデーション | Bicyclic Heteroaryl Derivatives as CFTR Enhancers |
CN113461694A (en) * | 2021-08-05 | 2021-10-01 | 广东西捷药业有限公司 | Vardenafil analogue and synthetic method and application thereof |
CN113583003A (en) * | 2021-08-05 | 2021-11-02 | 广东西捷药业有限公司 | Vardenafil analogue and synthetic method and application thereof |
Family Cites Families (39)
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BE791025A (en) | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | HETEROCYCLIC COMPOUNDS |
GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
DK109578A (en) | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS |
US4308384A (en) | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
US4479210A (en) * | 1982-11-19 | 1984-10-23 | U.S. Philips Corporation | Record-disc player |
GB9301192D0 (en) | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
US5656629A (en) * | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
ATE219765T1 (en) * | 1995-04-10 | 2002-07-15 | Fujisawa Pharmaceutical Co | INDOLE DERIVATIVES AS CGMP-PDE INHIBITORS |
EP0882718B1 (en) * | 1995-12-28 | 2005-08-31 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
DE19812462A1 (en) * | 1998-03-23 | 1999-09-30 | Bayer Ag | New phosphodiesterase inhibiting 2-phenyl-imidazotriazinone derivatives useful for treating e.g. cardiovascular, cerebrovascular and/or urogenital diseases |
IL135462A0 (en) | 1997-11-12 | 2001-05-20 | Bayer Ag | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
CN100436418C (en) * | 1997-12-12 | 2008-11-26 | Osi制药公司 | N-Benzyl-3-indenylacetamides derivatives for treating neoplasia |
US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
DE19827640A1 (en) | 1998-06-20 | 1999-12-23 | Bayer Ag | New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction |
IL132406A0 (en) * | 1998-10-21 | 2001-03-19 | Pfizer Prod Inc | Treatment of bph with cgmp elevators |
US6225315B1 (en) * | 1998-11-30 | 2001-05-01 | Pfizer Inc | Method of treating nitrate-induced tolerance |
FR2792634B1 (en) * | 1999-04-20 | 2001-06-01 | Synthelabo | 2-ALCOXY-CYCLOBUTENE-3,4-DIONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
IL130968A (en) * | 1999-07-15 | 2002-12-01 | Shmuel Simon | Pharmaceutical composition comprising sildenafil or its analogs, useful for the treatment of tinnitus and hearing loss |
AU775102B2 (en) * | 1999-09-13 | 2004-07-15 | David M. Swope | Composition and method for decreasing neurologic symptomatology |
DE19943815A1 (en) * | 1999-09-14 | 2001-03-15 | Merck Patent Gmbh | Use of thienopyrimidines |
TWI265925B (en) * | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
CA2323008C (en) * | 1999-10-11 | 2005-07-12 | Pfizer Inc. | Pharmaceutically active compounds |
ATE341329T1 (en) * | 1999-10-12 | 2006-10-15 | Lilly Icos Llc | MEDICINAL PRODUCTS FOR THE TREATMENT OF NEUROPATHIES |
IL152925A (en) * | 1999-10-21 | 2010-04-15 | Pfizer | Pharmaceutical compositions for treatment of neuropathy comprising an inhibitor of cyclic guanosine 3',5'-monophosphate phosphodiesterase 5 and either gabapentin or pregabalin |
TW200400821A (en) | 1999-11-02 | 2004-01-16 | Pfizer | Pharmaceutical composition (II) useful for treating or preventing pulmonary hypertension in a patient |
GB0008694D0 (en) * | 2000-04-07 | 2000-05-31 | Novartis Ag | Organic compounds |
JP2004500425A (en) * | 2000-04-19 | 2004-01-08 | リリー アイコス リミテッド ライアビリティ カンパニー | Use of cyclic GMP-specific phosphodiesterase inhibitors for the treatment of Parkinson's disease |
AU2001257146B2 (en) * | 2000-04-19 | 2006-11-30 | Johns Hopkins University | Methods for prevention and treatment of gastrointestinal disorders |
KR20030023747A (en) * | 2000-08-11 | 2003-03-19 | 화이자 인코포레이티드 | Treatment of the insulin resistance syndrome |
CA2419623A1 (en) * | 2000-08-30 | 2002-03-07 | Lilly Icos Llc | Method for treatment of migraine using pde5 inhibitors |
GB0025782D0 (en) * | 2000-10-20 | 2000-12-06 | Pfizer Ltd | Use of inhibitors |
AU2002226633A1 (en) * | 2001-02-02 | 2002-08-12 | Pfizer Limited | Treatment of diabetes mellitus using vardenafil |
DE10107639A1 (en) | 2001-02-15 | 2002-08-22 | Bayer Ag | 2-alkoxyphenyl substituted imidazotriazinones |
EP1392314B1 (en) * | 2001-05-09 | 2006-12-20 | Bayer HealthCare AG | NOVEL USE OF 2-[2-Ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on |
DE10135815A1 (en) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
GB0129274D0 (en) * | 2001-12-06 | 2002-01-23 | Pfizer Ltd | Novel kit |
JP2005527510A (en) * | 2002-03-06 | 2005-09-15 | セレジー ファーマシューティカルズ インコーポレーティッド | Formulations and methods for using nitric oxide mimetics in the treatment of cancer |
-
2001
- 2001-07-23 DE DE10135815A patent/DE10135815A1/en not_active Withdrawn
-
2002
- 2002-07-17 NZ NZ530703A patent/NZ530703A/en unknown
- 2002-07-17 UA UA2004021279A patent/UA76997C2/en unknown
- 2002-07-17 HU HU0500734A patent/HUP0500734A3/en unknown
- 2002-07-17 IL IL15984002A patent/IL159840A0/en unknown
- 2002-07-17 KR KR10-2004-7001050A patent/KR20040032865A/en not_active Application Discontinuation
- 2002-07-17 AU AU2002319296A patent/AU2002319296B2/en not_active Ceased
- 2002-07-17 RU RU2004105265/15A patent/RU2321406C9/en not_active IP Right Cessation
- 2002-07-17 CA CA002454414A patent/CA2454414A1/en not_active Abandoned
- 2002-07-17 DE DE50213840T patent/DE50213840D1/en not_active Expired - Fee Related
- 2002-07-17 EP EP06017257A patent/EP1733728A3/en not_active Withdrawn
- 2002-07-17 CZ CZ2004128A patent/CZ2004128A3/en unknown
- 2002-07-17 EE EEP200400056A patent/EE200400056A/en unknown
- 2002-07-17 MX MXPA04000675A patent/MXPA04000675A/en active IP Right Grant
- 2002-07-17 CN CNA028144759A patent/CN1649593A/en active Pending
- 2002-07-17 US US10/483,462 patent/US6930108B2/en not_active Expired - Fee Related
- 2002-07-17 PL PL02373392A patent/PL373392A1/en not_active Application Discontinuation
- 2002-07-17 ES ES02748858T patent/ES2330418T3/en not_active Expired - Lifetime
- 2002-07-17 AT AT02748858T patent/ATE442144T1/en not_active IP Right Cessation
- 2002-07-17 EP EP02748858A patent/EP1474150B1/en not_active Expired - Lifetime
- 2002-07-17 WO PCT/EP2002/007959 patent/WO2003011262A2/en active Application Filing
- 2002-07-17 JP JP2003516493A patent/JP2005504751A/en active Pending
- 2002-07-17 SK SK44-2004A patent/SK442004A3/en not_active Application Discontinuation
- 2002-07-17 BR BR0211359-7A patent/BR0211359A/en not_active IP Right Cessation
-
2004
- 2004-01-14 BG BG108533A patent/BG108533A/en unknown
- 2004-01-19 EC EC2004004956A patent/ECSP044956A/en unknown
- 2004-01-22 MA MA27497A patent/MA26128A1/en unknown
- 2004-01-22 HR HRP20040065 patent/HRP20040065A2/en not_active Application Discontinuation
- 2004-01-22 NO NO20040294A patent/NO20040294L/en not_active Application Discontinuation
- 2004-02-23 CO CO04015666A patent/CO5560536A2/en not_active Application Discontinuation
-
2005
- 2005-06-17 US US11/156,082 patent/US7276504B2/en not_active Expired - Fee Related
-
2007
- 2007-10-01 US US11/906,382 patent/US20080085897A1/en not_active Abandoned
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