AU2002314044A1 - Novel use of 2-phenyl-substituted imidazotriazinones - Google Patents

Novel use of 2-phenyl-substituted imidazotriazinones

Info

Publication number
AU2002314044A1
AU2002314044A1 AU2002314044A AU2002314044A AU2002314044A1 AU 2002314044 A1 AU2002314044 A1 AU 2002314044A1 AU 2002314044 A AU2002314044 A AU 2002314044A AU 2002314044 A AU2002314044 A AU 2002314044A AU 2002314044 A1 AU2002314044 A1 AU 2002314044A1
Authority
AU
Australia
Prior art keywords
phenyl
novel use
substituted imidazotriazinones
imidazotriazinones
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002314044A
Other versions
AU2002314044B2 (en
Inventor
Tiemo Joerg Bandel
Wolfgang Barth
Erwin Bischoff
Helmut Haning
Ulrich Niewohner
Afssaneh Rahbar
Franz Josef Van Der Staay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10126198A external-priority patent/DE10126198A1/en
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Priority claimed from PCT/EP2002/005002 external-priority patent/WO2002089808A1/en
Publication of AU2002314044A1 publication Critical patent/AU2002314044A1/en
Application granted granted Critical
Publication of AU2002314044B2 publication Critical patent/AU2002314044B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002314044A 2001-05-09 2002-05-07 Novel use of 2-phenyl-substituted imidazotriazinones Ceased AU2002314044B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10122576.8 2001-05-09
DE10122576 2001-05-09
DE10126198.5 2001-05-30
DE10126198A DE10126198A1 (en) 2001-05-09 2001-05-30 New use of 2-phenyl-substituted imidazotriazinones
PCT/EP2002/005002 WO2002089808A1 (en) 2001-05-09 2002-05-07 Novel use of 2-phenyl-substituted imidazotriazinones

Publications (2)

Publication Number Publication Date
AU2002314044A1 true AU2002314044A1 (en) 2003-05-01
AU2002314044B2 AU2002314044B2 (en) 2006-09-21

Family

ID=26009261

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002314044A Ceased AU2002314044B2 (en) 2001-05-09 2002-05-07 Novel use of 2-phenyl-substituted imidazotriazinones

Country Status (15)

Country Link
US (1) US20040152700A1 (en)
EP (1) EP1392314B1 (en)
JP (1) JP4540295B2 (en)
CN (1) CN1633298A (en)
AT (1) ATE348618T1 (en)
AU (1) AU2002314044B2 (en)
BR (1) BR0209541A (en)
CA (1) CA2449163C (en)
DE (1) DE50209015D1 (en)
DK (1) DK1392314T3 (en)
ES (1) ES2278927T3 (en)
IL (1) IL158738A0 (en)
MX (1) MXPA03010119A (en)
PL (1) PL363679A1 (en)
WO (1) WO2002089808A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1049695T3 (en) * 1997-11-12 2002-05-13 Bayer Ag 2-Phenyl-substituted imidazotriazinones as phosphodiesterase inhibitors
DE10135815A1 (en) * 2001-07-23 2003-02-06 Bayer Ag Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain
DE10232113A1 (en) * 2002-07-16 2004-01-29 Bayer Ag Medicinal products containing vardenafil hydrochloride trihydrate
JP4838792B2 (en) * 2004-03-05 2011-12-14 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Novel uses for PDE5 inhibitors
DE102004023069A1 (en) 2004-05-11 2005-12-08 Bayer Healthcare Ag New dosage forms of the PDE 5 inhibitor vardenafil
DE102004038328A1 (en) * 2004-08-06 2006-03-16 Bayer Healthcare Ag New uses of 2-phenyl-substituted imidazotriazinone derivatives
DE102005001989A1 (en) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenous formulations of PDE inhibitors
DE102005009241A1 (en) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Dosage forms with controlled bioavailability
DE102005009240A1 (en) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Dosage forms with improved pharmacokinetic properties
BRPI0616633A2 (en) * 2005-09-29 2011-06-28 Bayer Healthcare Ag pde inhibitors and combinations thereof for the treatment of urological disorders
US8841300B2 (en) 2006-10-02 2014-09-23 Jerry M. Held Treatment for Parkinson's disease—combination high dose serotonergic synaptic reuptake inhibitor with phosphodiesterase inhibitor
AU2008254424B2 (en) 2007-05-18 2012-12-20 Vivus, Inc. Novel combinations comprising a phosphodiesterase-5 inhibitor and their use
CA2689638A1 (en) * 2007-06-13 2008-12-18 Bayer Schering Pharma Aktiengesellschaft Pde inhibitors for the treatment of hearing impairment
CN101965348B (en) * 2007-09-06 2013-11-13 上海特化医药科技有限公司 Process for preparing vardenafil and intermediates thereof
JP6120985B2 (en) * 2012-12-04 2017-04-26 アリビオ, インコーポレーテッド Composition for suppressing apoptosis of nerve cells, comprising a phosphodiesterase type 5 activity inhibitor
JP2022509815A (en) 2018-11-28 2022-01-24 トパデュール ファルマ アーゲー New dual-acting soluble guanylate cyclase activators and phosphodiesterase inhibitors and their uses
CN113493459B (en) * 2020-04-07 2022-12-13 广州白云山医药集团股份有限公司白云山制药总厂 PDE5 inhibitor compound, preparation method and application thereof

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2705715A (en) * 1952-10-29 1955-04-05 American Cyanamid Co Purine compounds and methods of preparing the same
CH367510A (en) * 1957-11-27 1963-02-28 Ciba Geigy Process for the production of new sulfonamides
US3169129A (en) * 1963-05-10 1965-02-09 American Cyanamid Co 2-ortho-hydroxy-phenyl-4-(3h)-quinazolinones
US3333840A (en) * 1964-11-30 1967-08-01 Harbison Walker Refractories Method of lining a metallurgical furnace and the product thereof
USRE26565E (en) * 1966-03-02 1969-04-29 Table iii
GB1493685A (en) * 1970-12-15 1977-11-30 May & Baker Ltd 8-azapurinones
BE791025A (en) * 1971-11-19 1973-05-07 Allen & Hanburys Ltd HETEROCYCLIC COMPOUNDS
GB1457873A (en) * 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
US4052390A (en) * 1973-06-12 1977-10-04 May & Baker Limited Azapurinones
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
GB1561345A (en) * 1976-10-22 1980-02-20 May & Baker Ltd 8 - azapuring - 6 - ones
US4159330A (en) * 1976-11-02 1979-06-26 Carlo Erba S.P.A. 2-Disubstituted phenyl-3,4-dihydro-4-oxo-quinazoline derivatives and process for their preparation
DK109578A (en) * 1977-03-25 1978-09-26 Allen & Hanburys Ltd PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS
EP0054132B1 (en) * 1980-12-12 1984-10-10 Dr. Karl Thomae GmbH Pyrimidones, their preparation and medicines containing them
US4431440A (en) * 1981-02-20 1984-02-14 American Cyanamid Company Method to alter or control the development and/or the life cycle of various plant species
JPS61237112A (en) * 1985-04-12 1986-10-22 Matsushita Electric Works Ltd Electric power controller circuit of electrical equipment
CA1303037C (en) * 1987-02-02 1992-06-09 Smith Kline & French Laboratories Limited Purinone derivatives as bronchodilators vasodilators and anti-allergic agents
US5254571A (en) * 1988-04-21 1993-10-19 Smith Kline & French Laboratories Ltd. Chemical compounds
ES2058527T3 (en) * 1988-06-16 1994-11-01 Smith Kline French Lab CONDENSED DERIVATIVES OF PIRIMIDINE PROCEDURE AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
US5075310A (en) * 1988-07-01 1991-12-24 Smith Kline & French Laboratories, Ltd. Pyrimidone derivatives as bronchodilators
US4923874A (en) * 1988-07-21 1990-05-08 G. D. Searle & Co. Use of 8-azapurin-6-one derivatives for control of hypertension
GB8817651D0 (en) * 1988-07-25 1988-09-01 Smith Kline French Lab Chemical compounds
GB8827988D0 (en) * 1988-11-30 1989-01-05 Smith Kline French Lab Chemical compounds
US5574020A (en) * 1989-09-28 1996-11-12 Eli Lilly And Company Tilmicosin formulation
JPH05506011A (en) * 1990-04-11 1993-09-02 ジ・アップジョン・カンパニー Taste masking of ibuprofen by fluidized bed coating
US5250534A (en) * 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
GB9114760D0 (en) * 1991-07-09 1991-08-28 Pfizer Ltd Therapeutic agents
US5316906A (en) * 1991-08-23 1994-05-31 Molecular Probes, Inc. Enzymatic analysis using substrates that yield fluorescent precipitates
GB9126260D0 (en) * 1991-12-11 1992-02-12 Pfizer Ltd Therapeutic agents
US5294612A (en) * 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
US5734053A (en) * 1992-06-26 1998-03-31 Pfizer Inc Purinone antianginal agents
GB9218322D0 (en) * 1992-08-28 1992-10-14 Pfizer Ltd Therapeutic agents
US6143746A (en) * 1994-01-21 2000-11-07 Icos Corporation Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
GB9423911D0 (en) * 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
US6548490B1 (en) * 1997-10-28 2003-04-15 Vivus, Inc. Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
DK1049695T3 (en) * 1997-11-12 2002-05-13 Bayer Ag 2-Phenyl-substituted imidazotriazinones as phosphodiesterase inhibitors
DE19812462A1 (en) * 1998-03-23 1999-09-30 Bayer Ag New phosphodiesterase inhibiting 2-phenyl-imidazotriazinone derivatives useful for treating e.g. cardiovascular, cerebrovascular and/or urogenital diseases
US6221402B1 (en) * 1997-11-20 2001-04-24 Pfizer Inc. Rapidly releasing and taste-masking pharmaceutical dosage form
GT199900061A (en) * 1998-05-15 2000-10-14 Pfizer PHARMACEUTICAL FORMULATIONS.
DE19827640A1 (en) * 1998-06-20 1999-12-23 Bayer Ag New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction
JP2002528773A (en) * 1998-10-27 2002-09-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Driving circuit and device for matrix display panel
US6075028A (en) * 1999-09-23 2000-06-13 Graham; Richard Method of treating Tourette's syndrome and related CNS disorders
US6503908B1 (en) * 1999-10-11 2003-01-07 Pfizer Inc Pharmaceutically active compounds
GB9923968D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Therapeutic agents
IL150022A0 (en) * 1999-12-24 2002-12-01 Bayer Ag Imidazo [1,3,5] triazinones and the use thereof
CN1630532A (en) * 2000-04-19 2005-06-22 约翰斯霍普金斯大学 Methods for prevention and treatment of gastrointestinal disorders
WO2002009713A2 (en) * 2000-08-01 2002-02-07 Bayer Aktiengesellschaft Selective pde 2 inhibitors, used as medicaments for improving cognition
DE60103299T2 (en) * 2000-10-30 2005-05-12 Lupin Ltd., Mumbai FAST-CRUSHING CEFUROXIM AXETIL-CONTAINING MEDICAMENT COMPOSITION WITH DELAYED ACTIVE INGREDIENTS
WO2002064119A1 (en) * 2001-02-15 2002-08-22 Tanabe Seiyaku Co., Ltd. Tablets quickly disintegrated in oral cavity
DE10118306A1 (en) * 2001-04-12 2002-10-17 Bayer Ag Composition for intranasal administration of imidazo-triazinone derivative cGMP PDE inhibitor for treatment of erectile dysfunction, also containing local anesthetic to prevent nasal blockage and improve absorption
US7939102B2 (en) * 2002-06-07 2011-05-10 Torrent Pharmaceuticals Ltd. Controlled release formulation of lamotrigine
DE10232113A1 (en) * 2002-07-16 2004-01-29 Bayer Ag Medicinal products containing vardenafil hydrochloride trihydrate
DE10325813B4 (en) * 2003-06-06 2007-12-20 Universitätsklinikum Freiburg Prophylaxis and / or therapy in portal hypertension
DE102004023069A1 (en) * 2004-05-11 2005-12-08 Bayer Healthcare Ag New dosage forms of the PDE 5 inhibitor vardenafil

Similar Documents

Publication Publication Date Title
AUPR879601A0 (en) Novel chemical compounds and their use
AU2002352221A1 (en) Bicyclic n-arylamides
AU2002314044A1 (en) Novel use of 2-phenyl-substituted imidazotriazinones
AU2002359165A1 (en) Novel compounds
AU2002359320A1 (en) Novel anit-infectives
AUPR879701A0 (en) Novel chemical compounds and their use
AU2002356615A1 (en) Novel utilization of cyclopentabenzofurans
AU2002329441A1 (en) Process for the preparation of 3 - isochromanone
AU2002358085A1 (en) Process for the preparation of 4-methyl-7-aminoquinolones
AU2002360974A1 (en) Novel use of alloys
AU2002251543A1 (en) Novel atisane compound and use thereof
AU2003238034A1 (en) Novel use of imidazotriazinones
AU2002324291A1 (en) Process for the preparation of beta-ionylideneacetaldehyde
EP1238585B8 (en) Use of esterquats
AU2002359898A1 (en) Preparation of alpha-diimines
AU2002300773A1 (en) Preparation of Dialkylpyridylboranes
AU2001288046A1 (en) Novel use of tricyclic compound
AU2002341119A1 (en) Use of oligomeric proanthrocyanidins
AU2002255261A1 (en) Novel use of arylethenessulfonamide derivatives
AU2002307219A1 (en) Purification of difluoromethane
AU2002338934A1 (en) Preparation of benzosuberonylpiperidine compounds
AU2002317699A1 (en) Improved synthesis of allofuranose
AU2002254880A1 (en) Novel heteroaryl-diazabicyclo-alkanes as cns-modulators
AU2002253663A1 (en) Novel maxizyme
AU2002254979A1 (en) Novel sulfonylamino-pyrimidines