AU2002310768A1 - Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives as medicaments for the treatment of pain - Google Patents

Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives as medicaments for the treatment of pain

Info

Publication number
AU2002310768A1
AU2002310768A1 AU2002310768A AU2002310768A AU2002310768A1 AU 2002310768 A1 AU2002310768 A1 AU 2002310768A1 AU 2002310768 A AU2002310768 A AU 2002310768A AU 2002310768 A AU2002310768 A AU 2002310768A AU 2002310768 A1 AU2002310768 A1 AU 2002310768A1
Authority
AU
Australia
Prior art keywords
diaza
oxa
spiro
medicaments
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002310768A
Other versions
AU2002310768B2 (en
Inventor
Helmut Heinrich Buschmann
Werner Gunter Englberger
Tieno Germann
Hagen-Heinrich Hennies
Jorg Holenz
Corinna Maul
Bernd Sundermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10130020A external-priority patent/DE10130020A1/en
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2002310768A1 publication Critical patent/AU2002310768A1/en
Application granted granted Critical
Publication of AU2002310768B2 publication Critical patent/AU2002310768B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002310768A 2001-06-25 2002-06-21 Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives as medicaments for the treatment of pain Ceased AU2002310768B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10130020.4 2001-06-25
DE10130020A DE10130020A1 (en) 2001-06-25 2001-06-25 Substituted 1-oxa-2,8-diaza-spiro [4.5] dec-2-ene derivatives
PCT/EP2002/006880 WO2003000699A1 (en) 2001-06-25 2002-06-21 Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives as medicaments for the treatment of pain

Publications (2)

Publication Number Publication Date
AU2002310768A1 true AU2002310768A1 (en) 2003-06-19
AU2002310768B2 AU2002310768B2 (en) 2007-01-11

Family

ID=7689008

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002310768A Ceased AU2002310768B2 (en) 2001-06-25 2002-06-21 Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives as medicaments for the treatment of pain

Country Status (30)

Country Link
US (2) US8048890B2 (en)
EP (1) EP1401841B1 (en)
JP (1) JP4410554B2 (en)
KR (1) KR100917112B1 (en)
CN (1) CN1315840C (en)
AR (1) AR036098A1 (en)
AT (1) ATE302782T1 (en)
AU (1) AU2002310768B2 (en)
BR (1) BR0211053A (en)
CA (1) CA2451859C (en)
CO (1) CO5540301A2 (en)
CZ (1) CZ20033432A3 (en)
DE (2) DE10130020A1 (en)
DK (1) DK1401841T3 (en)
EC (1) ECSP034924A (en)
ES (1) ES2245402T3 (en)
HK (1) HK1064669A1 (en)
HU (1) HU228774B1 (en)
IL (2) IL159544A0 (en)
MX (1) MXPA03012013A (en)
NO (1) NO332217B1 (en)
NZ (1) NZ530689A (en)
PE (1) PE20030146A1 (en)
PL (1) PL214290B1 (en)
PT (1) PT1401841E (en)
RU (1) RU2296128C2 (en)
SI (1) SI1401841T1 (en)
SK (1) SK287390B6 (en)
WO (1) WO2003000699A1 (en)
ZA (1) ZA200400489B (en)

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DE10130020A1 (en) 2001-06-25 2003-12-04 Gruenenthal Gmbh Substituted 1-oxa-2,8-diaza-spiro [4.5] dec-2-ene derivatives
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DE102005016170A1 (en) * 2005-04-07 2006-10-12 Grünenthal GmbH 4,5,6,7-tetrahydro-isoxazolo (4,5c) pyridine compounds and their use for the preparation of medicaments
DE102005023784A1 (en) * 2005-05-19 2006-11-30 Grünenthal GmbH Substituted spiro compounds and their use for the preparation of medicaments
DE102005044813A1 (en) 2005-05-19 2007-10-04 Grünenthal GmbH Substituted spiro compounds and their use for the preparation of medicaments
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US9340558B2 (en) 2007-11-02 2016-05-17 Pain Therapeutics Inc. Filamin a binding anti-inflammatory and analgesic
US8614324B2 (en) * 2008-10-31 2013-12-24 Pain Therapeutics, Inc. Filamin A binding anti-inflammatory and analgesic
US8580808B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutic, Inc. Filamin A-binding anti-inflammatory analgesic
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US8580809B2 (en) * 2009-10-30 2013-11-12 Pain Therapeutics, Inc. Filamin A-binding anti-inflammatory analgesic
US8822464B2 (en) 2011-11-28 2014-09-02 Boehringer Ingelheim International Gmbh N-aryl-piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors
US8741892B2 (en) 2011-12-05 2014-06-03 Boehringer Ingelheim International Gmbh Compounds
US8642774B2 (en) * 2011-12-08 2014-02-04 Boehringer Ingelheim International Gmbh Compounds
US8846948B2 (en) 2011-12-13 2014-09-30 Boehringer Ingelheim International Gmbh Compounds
US8796467B2 (en) 2011-12-13 2014-08-05 Boehringer Ingelheim International Gmbh Compounds
US8716277B2 (en) 2011-12-14 2014-05-06 Boehringer Ingelheim International Gmbh Substituted imidazole compounds useful as positive allosteric modulators of mGlu5 receptor activity
US8883789B2 (en) 2011-12-14 2014-11-11 Boehringer Ingelheim International Gmbh Piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors
US8937176B2 (en) 2011-12-14 2015-01-20 Boehringer Ingelheim International Gmbh Compounds
US8889677B2 (en) 2012-01-17 2014-11-18 Boehringer Ingellheim International GmbH Substituted triazoles useful as mGlu5 receptor modulators
JP6566867B2 (en) 2012-07-13 2019-08-28 ペイン セラピューティクス インコーポレイテッド Alzheimer's disease assay in living patients
ES2716049T3 (en) 2012-07-13 2019-06-07 Pain Therapeutics Inc A method to inhibit tau phosphorylation
US9433604B2 (en) 2013-10-08 2016-09-06 Pain Therapeutics Inc. Method for inhibiting growth of cancer cells
AR107361A1 (en) 2016-01-13 2018-04-25 Gruenenthal Gmbh DERIVATIVES OF 3- (CARBOXIETIL) -8-AMINO-2-OXO-1,3-DIAZA-ESPIRO- [4.5] -DECANO
US20170197970A1 (en) 2016-01-13 2017-07-13 Gruenenthal Gmbh 3-((Hetero-)Aryl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives
EA037481B1 (en) 2016-01-13 2021-04-01 Грюненталь Гмбх 3-((hetero)aryl)alkyl-8-amino-2-oxo-1,3-diazaspiro[4.5]decane derivatives
PT3402785T (en) 2016-01-13 2020-05-15 Gruenenthal Gmbh 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
US20170197949A1 (en) 2016-01-13 2017-07-13 Gruenenthal Gmbh 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives
SI3612520T1 (en) 2017-04-12 2022-01-31 Il Dong Pharmaceutical Co., Ltd. Isoxazole derivatives as nuclear receptor agonists and uses thereof
CN109793713B (en) * 2019-03-26 2021-05-28 李世系 Short-acting hypnotic and sedative pharmaceutical composition for anesthesia and preparation method and application of injection thereof

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