AU2002300734A1 - Fusion protein having enhanced in vivo erythropoietin activity - Google Patents
Fusion protein having enhanced in vivo erythropoietin activityInfo
- Publication number
- AU2002300734A1 AU2002300734A1 AU2002300734A AU2002300734A AU2002300734A1 AU 2002300734 A1 AU2002300734 A1 AU 2002300734A1 AU 2002300734 A AU2002300734 A AU 2002300734A AU 2002300734 A AU2002300734 A AU 2002300734A AU 2002300734 A1 AU2002300734 A1 AU 2002300734A1
- Authority
- AU
- Australia
- Prior art keywords
- enhanced
- fusion protein
- erythropoietin activity
- vivo
- vivo erythropoietin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- 102000037240 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR2001-75994 | 2001-12-03 | ||
| KR10-2001-0075994A KR100467751B1 (en) | 2001-12-03 | 2001-12-03 | Fusion protein having the enhanced in vivo erythropoietin activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002300734A1 true AU2002300734A1 (en) | 2003-06-12 |
| AU2002300734B2 AU2002300734B2 (en) | 2009-01-08 |
Family
ID=36123483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002300734A Ceased AU2002300734B2 (en) | 2001-12-03 | 2002-08-13 | Fusion protein having enhanced in vivo erythropoietin activity |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7091326B2 (en) |
| EP (1) | EP1316561B1 (en) |
| JP (1) | JP4035400B2 (en) |
| KR (1) | KR100467751B1 (en) |
| CN (1) | CN100400548C (en) |
| AT (1) | ATE352565T1 (en) |
| AU (1) | AU2002300734B2 (en) |
| BR (1) | BR0203386A (en) |
| CA (1) | CA2400908C (en) |
| DE (1) | DE60217804T2 (en) |
| ES (1) | ES2280487T3 (en) |
| MX (1) | MXPA02008454A (en) |
| NZ (1) | NZ520776A (en) |
| RU (1) | RU2232192C2 (en) |
| TW (1) | TWI243827B (en) |
| WO (1) | WO2003048210A1 (en) |
| ZA (1) | ZA200206879B (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| CN1897959A (en) * | 2003-09-29 | 2007-01-17 | 沃伦药品公司 | Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions |
| CN100516225C (en) * | 2004-07-30 | 2009-07-22 | 成都地奥制药集团有限公司 | Interfusion protein of human serum protein and erythropoietin |
| UA100222C2 (en) * | 2005-08-05 | 2012-12-10 | Араім Фармасьютікалз, Інк. | Tissue protective peptides and uses thereof |
| US7625564B2 (en) | 2006-01-27 | 2009-12-01 | Novagen Holding Corporation | Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo |
| US7553941B2 (en) * | 2006-02-03 | 2009-06-30 | Modigene Inc | Long-acting polypeptides and methods of producing same |
| US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
| US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| CN100436482C (en) * | 2006-04-14 | 2008-11-26 | 东莞太力生物工程有限公司 | Long effective amalgamation protein of erythropoietin of human, preparing and purifying methods |
| WO2009012600A1 (en) | 2007-07-26 | 2009-01-29 | Novagen Holding Corporation | Fusion proteins |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
| CN102994547B (en) * | 2011-09-08 | 2015-05-13 | 哈药集团技术中心 | Recombinant human erythropoietin-CTP fusion protein production process and application |
| CN103182073A (en) * | 2011-12-29 | 2013-07-03 | 哈药集团技术中心 | Pharmaceutical injection of recombinant human interferon alpha-CTP fusion protein |
| PE20142405A1 (en) | 2012-04-19 | 2015-01-25 | Opko Biolog Ltd | LONG-ACTING OXYTOMODULIN VARIANTS AND METHODS OF PRODUCING THEM |
| EP3848386A1 (en) * | 2012-11-20 | 2021-07-14 | OPKO Biologics Ltd. | Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides |
| US20160024181A1 (en) | 2013-03-13 | 2016-01-28 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| WO2016092550A2 (en) * | 2014-12-10 | 2016-06-16 | Opko Biologics Ltd. | Methods of producing long acting ctp-modified polypeptides |
| PL3310347T3 (en) | 2015-06-19 | 2021-12-27 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| CN110393801A (en) * | 2018-04-24 | 2019-11-01 | 中国科学院上海生命科学研究院 | Target the application that interstitialcellstimulating hormone (ICSH) promotes body hematopoiesis |
| CN112175088B (en) * | 2019-07-02 | 2023-03-28 | 江苏晟斯生物制药有限公司 | FIX fusion proteins, conjugates and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6225449B1 (en) * | 1991-10-04 | 2001-05-01 | Washington University | Hormone analogs with multiple CTP extensions |
| CA2053864C (en) * | 1989-02-21 | 2001-11-20 | Irving Boime | Modified forms of reproductive hormones |
| US5856298A (en) * | 1989-10-13 | 1999-01-05 | Amgen Inc. | Erythropoietin isoforms |
| PT695307E (en) * | 1993-04-20 | 2000-05-31 | Univ Washington | PROTEINS AND MODIFIED PEPTID DRUGS |
| IL192290A0 (en) | 1993-08-17 | 2008-12-29 | Kirin Amgen Inc | Erythropoietin analogs |
| CZ299516B6 (en) | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Erythropoietin glycoprotein conjugate, process for its preparation and use and pharmaceutical composition containing thereof |
| JO2291B1 (en) * | 1999-07-02 | 2005-09-12 | اف . هوفمان لاروش ايه جي | Erythopintin derivatives |
| ATE407697T1 (en) | 1999-07-13 | 2008-09-15 | Bolder Biotechnology Inc | ERYTHROPOIETIN IMMUNOLOBULIN FUSION PROTEINS |
| WO2001036489A2 (en) | 1999-11-12 | 2001-05-25 | Merck Patent Gmbh | Erythropoietin forms with improved properties |
| EP1342730B1 (en) | 2000-12-11 | 2006-03-15 | Cheil Jedang Corporation | Fusion protein having the enhanced in vivo activity of erythropoietin |
-
2001
- 2001-12-03 KR KR10-2001-0075994A patent/KR100467751B1/en not_active IP Right Cessation
-
2002
- 2002-07-17 US US10/196,183 patent/US7091326B2/en not_active Expired - Lifetime
- 2002-08-06 WO PCT/KR2002/001493 patent/WO2003048210A1/en active Search and Examination
- 2002-08-09 TW TW091117964A patent/TWI243827B/en not_active IP Right Cessation
- 2002-08-13 AU AU2002300734A patent/AU2002300734B2/en not_active Ceased
- 2002-08-14 EP EP02255679A patent/EP1316561B1/en not_active Expired - Lifetime
- 2002-08-14 DE DE60217804T patent/DE60217804T2/en not_active Expired - Lifetime
- 2002-08-14 ES ES02255679T patent/ES2280487T3/en not_active Expired - Lifetime
- 2002-08-14 AT AT02255679T patent/ATE352565T1/en not_active IP Right Cessation
- 2002-08-14 NZ NZ520776A patent/NZ520776A/en not_active IP Right Cessation
- 2002-08-26 BR BR0203386-0A patent/BR0203386A/en not_active Application Discontinuation
- 2002-08-28 JP JP2002248825A patent/JP4035400B2/en not_active Expired - Fee Related
- 2002-08-28 ZA ZA200206879A patent/ZA200206879B/en unknown
- 2002-08-29 MX MXPA02008454A patent/MXPA02008454A/en active IP Right Grant
- 2002-08-29 CA CA2400908A patent/CA2400908C/en not_active Expired - Fee Related
- 2002-08-29 RU RU2002123286/13A patent/RU2232192C2/en not_active IP Right Cessation
- 2002-09-05 CN CNB021318832A patent/CN100400548C/en not_active Expired - Fee Related
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