AU2002236566A1 - Sildenafil citrate chewing gum formulations and methods of using the same - Google Patents

Sildenafil citrate chewing gum formulations and methods of using the same

Info

Publication number
AU2002236566A1
AU2002236566A1 AU2002236566A AU3656602A AU2002236566A1 AU 2002236566 A1 AU2002236566 A1 AU 2002236566A1 AU 2002236566 A AU2002236566 A AU 2002236566A AU 3656602 A AU3656602 A AU 3656602A AU 2002236566 A1 AU2002236566 A1 AU 2002236566A1
Authority
AU
Australia
Prior art keywords
methods
same
chewing gum
sildenafil citrate
gum formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002236566A
Inventor
Charlean Gmunder
Weisheng Li
Ronald Ream
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WM Wrigley Jr Co
Original Assignee
WM Wrigley Jr Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WM Wrigley Jr Co filed Critical WM Wrigley Jr Co
Publication of AU2002236566A1 publication Critical patent/AU2002236566A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/86—Addition of bitterness inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002236566A 2000-11-16 2001-11-13 Sildenafil citrate chewing gum formulations and methods of using the same Abandoned AU2002236566A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/714,571 2000-11-16
US09/714,571 US6531114B1 (en) 1999-04-06 2000-11-16 Sildenafil citrate chewing gum formulations and methods of using the same
PCT/US2001/046848 WO2002041840A2 (en) 2000-11-16 2001-11-13 Sildenafil citrate chewing gum formulations and methods of using the same

Publications (1)

Publication Number Publication Date
AU2002236566A1 true AU2002236566A1 (en) 2002-06-03

Family

ID=24870575

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002236566A Abandoned AU2002236566A1 (en) 2000-11-16 2001-11-13 Sildenafil citrate chewing gum formulations and methods of using the same

Country Status (4)

Country Link
US (2) US6531114B1 (en)
EP (1) EP1408933A4 (en)
AU (1) AU2002236566A1 (en)
WO (1) WO2002041840A2 (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US7935362B2 (en) * 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
RU2001126555A (en) * 1999-04-06 2003-06-20 Вм. Ригли Дж. Компани (Us) Pharmaceutical Chewing Gum Formulations
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US20020159956A1 (en) * 1999-04-06 2002-10-31 Ream Ronald L. Over-coated chewing gum formulations
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US6774128B2 (en) * 2000-04-19 2004-08-10 Johns Hopkins University Methods for prevention and treatment of gastrointestinal disorders
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
US6613346B2 (en) 2001-06-28 2003-09-02 Wm. Wrigley, Jr. Company Chewable product including active ingredient
US7138134B2 (en) * 2001-12-18 2006-11-21 Arizona Health Consulting Group, Llc Preparation and administration of jojoba product for reducing weight, fat and blood lipid levels
DE10262018B4 (en) * 2002-06-13 2007-09-06 Südzucker AG Mannheim/Ochsenfurt Compositions, foodstuffs, food and beverages, confectionery, animal feed, dietary special nutrition, child nutrition, sweeteners and pharmaceutical compositions containing condensed palatinose
US20040126448A1 (en) * 2002-08-05 2004-07-01 Nils-Olof Lindberg Sexual dysfunction compounds
SE0202365D0 (en) * 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
US20050042177A1 (en) * 2003-07-23 2005-02-24 Elan Pharma International Ltd. Novel compositions of sildenafil free base
US20060035905A1 (en) * 2004-02-06 2006-02-16 Becton, Dickinson And Company Formulations of phosphodiesterase 5 inhibitors and methods of use
JP4532950B2 (en) * 2004-03-24 2010-08-25 富士通株式会社 Optical switch and network system including the same
US20080226705A1 (en) * 2004-03-31 2008-09-18 Soltero Richard A Gel delivery system for oral administration of medicaments
US20070196495A1 (en) * 2004-03-31 2007-08-23 Richard Soltero Method for administering medicaments to subjects with swallowing difficulties and disorders
GB0417938D0 (en) * 2004-08-12 2004-09-15 Univ Bristol Elastomeric material exhibiting reduced adhesion and chewing gum composition containing it
WO2006037319A1 (en) * 2004-10-08 2006-04-13 Gumlink A/S Confectionery product
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP2010513465A (en) * 2006-12-21 2010-04-30 フイルメニツヒ ソシエテ アノニム Odor neutralizing composition
US20100209359A1 (en) * 2007-02-26 2010-08-19 Revolymer Limited Medicated chewing gum
JP2010518845A (en) * 2007-02-26 2010-06-03 リヴォリマー リミテッド Medicinal chewing gum
WO2009050203A1 (en) * 2007-10-15 2009-04-23 Revolymer Limited Solvent-free synthesis of amphiphilic polymeric material
US20090130179A1 (en) * 2007-11-16 2009-05-21 Cadbury Adams Usa Llc Confectionery compositions including markings for delivery of actives
EP2143336A1 (en) * 2008-07-08 2010-01-13 Alsiano A/S Powdered chewing gum compositions, the use thereof and a method for preparing such compositions
US20110097401A1 (en) * 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US9682093B2 (en) 2012-03-30 2017-06-20 Charles R. Drew University Of Medicine And Science Compositions and methods for treating or preventing metabolic syndrome disorders
US20140271923A1 (en) 2013-03-14 2014-09-18 Christopher Brian Reid Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions
NO2723977T3 (en) 2014-03-19 2018-03-10
US11071310B1 (en) * 2014-12-17 2021-07-27 Natalie Marie Lutz Oral therapy article, and methods of using same
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2020061584A1 (en) * 2018-09-21 2020-03-26 Msb Holdings, Inc. Taste-masked dosage forms

Family Cites Families (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3029189A (en) 1962-04-10 S-aryl-z-mno-x-qxazolibinones
US1298670A (en) 1915-06-11 1919-04-01 Stuart W Cramer Chewing-gum.
US1629461A (en) 1926-04-22 1927-05-17 Health Products Corp Chewing gum
US2892753A (en) 1957-02-26 1959-06-30 Boehringer Sohn Ingelheim Central nervous system stimulant
BE585778A (en) 1958-04-18
US3011949A (en) 1958-06-10 1961-12-05 Anthony G Bilotti Method of promoting release of active ingredients from slab chewing gum and product
GB942868A (en) 1959-07-17 1963-11-27 Air Prod & Chem Preparing triethylenediamine
US3047461A (en) 1960-06-10 1962-07-31 American Cyanamid Co Central nervous system stimulant
US3075884A (en) 1961-02-13 1963-01-29 American Chicle Co Slab chewing gums containing active ingredients and method of preparing same
US3196172A (en) 1963-05-20 1965-07-20 American Cyanamid Co Trifluoromethylphenylalkylenediamines
DE1216486B (en) 1964-04-23 1966-05-12 Merck Ag E Process for the production of coated tablets
US3308022A (en) 1964-06-25 1967-03-07 American Cyanamid Co Novel hypotensive compositions containing 1-substituted-3-cyano guanidines
US3498964A (en) 1966-08-29 1970-03-03 Takashi Hayashi Peripheral vasodilator peptide obtained from the animals of the family otariidae and method of preparing the same
US3590057A (en) 1967-12-21 1971-06-29 Sumitomo Chemical Co (alpha-(c5-c17)alkyl)benzyl fatty acid amides as cholesterol lowering agents
US3901248A (en) 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3877468A (en) 1970-07-22 1975-04-15 Leo Ab Chewable tobacco substitute composition
US3845217A (en) 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
FR2262005B1 (en) 1974-02-22 1978-01-06 Raffinage Cie Francaise
US3995064A (en) 1975-06-04 1976-11-30 Life Savers, Inc. Method and apparatus for forming chewing gum base and product
FR2345938A1 (en) 1976-03-05 1977-10-28 Choay Patrick Chewing gum contg. xanthine stimulants or mixts. - including plant extracts e.g. tea and coffee extracts
US4154814A (en) 1978-02-13 1979-05-15 EPS Chewing Gum, Inc. Therapeutic chewing gum
US4238510A (en) 1979-02-21 1980-12-09 Life Savers, Inc. Sugarless coating for chewing gum and confections and method
JPS6056143B2 (en) 1979-08-02 1985-12-09 山之内製薬株式会社 Amidine derivatives and their production method
US4238475A (en) 1979-08-01 1980-12-09 Life Savers Inc. Chewing cum capable of releasing finely divided water-insoluble materials therefrom
US4317838A (en) 1979-09-24 1982-03-02 Life Savers, Inc. Method for applying sugarless coating to chewing gum and confections
US4250195A (en) 1979-09-24 1981-02-10 Life Savers, Inc. Method for applying soft flexible sugar coating to fresh chewing gum and coated chewing gum product
US4374858A (en) 1979-10-04 1983-02-22 Warner-Lambert Company Aspartame sweetened chewing gum of improved sweetness stability
US4386063A (en) 1980-12-18 1983-05-31 International Flavors & Fragrances Inc. Flavor use of mixtures containing 1-n-butoxy-1-ethanol acetate
US4400372A (en) 1981-03-05 1983-08-23 Indiana University Foundation Chewing gum
US4386106A (en) 1981-12-01 1983-05-31 Borden, Inc. Process for preparing a time delayed release flavorant and an improved flavored chewing gum composition
US4452821A (en) 1981-12-18 1984-06-05 Gerhard Gergely Confectionery product, particularly chewing gum, and process for its manufacture
US4378374A (en) 1981-12-21 1983-03-29 Nabisco Brands, Inc. Chewing gum having improved softness
GB2125699B (en) 1982-02-22 1986-02-12 Bruss Ni Sanitarno Gigieniches Medicinal preparation having antinicotine effect and method for obtention thereof
DE3213284A1 (en) 1982-04-08 1983-10-13 Winfried 8451 Kümmersbruck Kruppa ANTI-CARIES CHEWING GUM
US4446135A (en) 1982-06-07 1984-05-01 Sterling Drug Inc. Chewable antacid tablets
US4512968A (en) 1982-11-30 1985-04-23 Lion Corporation Oral compositions
US4459311A (en) 1983-01-03 1984-07-10 Nabisco Brands, Inc. Process for preparing gum base
US4533556A (en) 1983-06-14 1985-08-06 Warner-Lambert Company Kola flavored chewing gum and preparation thereof
US4647450A (en) 1983-07-20 1987-03-03 Warner-Lambert Company Chewing gum compositions containing magnesium trisilicate absorbates
US4933184A (en) 1983-12-22 1990-06-12 American Home Products Corp. (Del) Menthol enhancement of transdermal drug delivery
US4563345A (en) 1984-01-23 1986-01-07 Arrick Robert A Chewing gum
US4753805A (en) 1984-01-31 1988-06-28 Warner-Lambert Company Tabletted chewing gum composition and method of preparation
US4639368A (en) 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
US4971787A (en) 1984-08-27 1990-11-20 Warner-Lambert Company Antacid chewing gum
US4894234A (en) 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for antiarrhythmics
US4935242A (en) 1984-10-05 1990-06-19 Warner-Lambert Company Novel drug delivery system for expectorants
US4929508A (en) 1984-10-05 1990-05-29 Warner-Lambert Company Novel drug delivery system for antitussives
US4555407A (en) 1984-12-24 1985-11-26 General Foods Corporation Continuous chewing gum method
AU5356586A (en) 1984-12-27 1986-07-29 Gergely, Gerhard Kaugummi und verfahren zu seiner herstellung
US4695463A (en) 1985-05-24 1987-09-22 Warner-Lambert Company Delivery system for active ingredients and preparation thereof
IT1189727B (en) 1985-08-30 1988-02-04 Roberto Cappellari CHEWING RUBBER WITH DIFFERENT EFFECT IN THE TASTE AND TIME
GB8522453D0 (en) 1985-09-11 1985-10-16 Lilly Industries Ltd Chewable capsules
US4753800A (en) 1985-10-04 1988-06-28 Warner-Lambert Company Medicament adsorbates and their preparation
GB2181646B (en) 1985-10-22 1989-09-20 David Morris Medicated chewing gum
ZA867327B (en) 1985-11-04 1987-05-27 Warner Lambert Co Flavored tableted chewing gum
US4882152A (en) 1985-12-20 1989-11-21 Yang Robert K Confectionery delivery system for laxatives, vitamins and antacids
US4929447A (en) 1986-01-07 1990-05-29 Warner-Lambert Company Encapsulation composition for use with chewing gum and edible products
US4849227A (en) 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
US4758424A (en) 1986-03-27 1988-07-19 Warner-Lambert Company Medicament adsorbates of decongestants with complex magnesium aluminum silicate and their preparation
US4711774A (en) 1986-03-27 1987-12-08 Warner-Lambert Company Medicament adsorbates with complex magnesium aluminum silicate and their preparation
US4716033A (en) 1986-03-27 1987-12-29 Warner-Lambert Company Medicament adsorbates with surfactant and their preparation
US4908211A (en) 1986-09-08 1990-03-13 Paz Armando F Chewing gum and ingredients to chemically inhibit formation of plaque and calculus
US4867989A (en) 1986-09-09 1989-09-19 Warner-Lambert Company Chewing gum mineral supplement
FR2607671B1 (en) 1986-12-04 1991-02-08 Gen Foods France PROCESS FOR THE DIRECT MANUFACTURE OF BASE GUM FOR MASTICATORY PASTE AND CHEWING GUM
GB8630273D0 (en) 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
US4828820A (en) 1987-01-15 1989-05-09 Warner-Lambert Company Chewable tooth cleaning composition
US4835162A (en) 1987-02-12 1989-05-30 Abood Leo G Agonists and antagonists to nicotine as smoking deterents
US5015464A (en) 1987-03-25 1991-05-14 Amway Corporation Antiplaque chewing gum
US4822816A (en) 1987-04-10 1989-04-18 Oxycal Laboratories, Inc. Compositions and methods for administering vitamin C
US4968716A (en) 1987-04-10 1990-11-06 Oxycal Laboratories, Inc. Compositions and methods for administering therapeutically active compounds
US5070085A (en) 1987-04-10 1991-12-03 Oxycal Laboratories, Inc. Compositions and methods for administering therapeutically active compounds
US4975270A (en) 1987-04-21 1990-12-04 Nabisco Brands, Inc. Elastomer encased active ingredients
IE59934B1 (en) 1987-06-19 1994-05-04 Elan Corp Plc Liquid suspension for oral administration
US4853212A (en) 1987-07-13 1989-08-01 Warner-Lambert Company Reduced base content chewing gum compositions having anesthetic properties
US4822597A (en) 1987-07-13 1989-04-18 Warner-Lambert Company Anesthetic-containing chewing gum compositions
US4832994A (en) 1987-09-02 1989-05-23 Fey Michael S Anti-smoking oral composition
FR2635441B1 (en) 1988-08-18 1991-12-27 Gen Foods France HIGH POLYMER BASE GUM BASE CONCENTRATES, THEIR PREPARATION PROCESS AND THEIR USE IN THE MANUFACTURE OF CHEWING GUM
US5013716A (en) 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
KR900007862A (en) 1988-11-10 1990-06-02 정보영 Inhibitor of Glucan Synthesis of F-1, F-2 Fractionated by Sephadex G-50 from Cacao Bean Husk Extract
US4938963A (en) 1988-11-22 1990-07-03 Parnell Pharmaceuticals, Inc. Method and composition for treating xerostomia
US5110608A (en) 1988-12-29 1992-05-05 Warner-Lambert Company Chewing gums having longer lasting sweetness
US5139787A (en) 1989-01-19 1992-08-18 Wm. Wrigley Jr. Company Gum composition containing dispersed porous beads containing active chewing gum ingredients and method
US4963369A (en) 1989-01-19 1990-10-16 Wm. Wrigley Jr. Co. Gum composition containing dispersed porous beads containing active chewing gum ingredients and method
US5154927A (en) 1989-01-19 1992-10-13 Wm. Wrigley Jr. Company Gum composition containing dispersed porous beads containing active chewing gum ingredients and method
US4968511A (en) 1989-03-10 1990-11-06 Amelia Ronald P D Composition and process for one-step chewing gum
SE463189B (en) 1989-03-13 1990-10-22 Eston Joensson PREPARED PROVIDED TO BE ADDED TO AMALGAM FILLINGS IN TEMPERATURE, THEREFORE, TO PREVENT OR REDUCE THE EXPOSURE OF MERCURY SILVER OR MERCURY SILVER
US4997659A (en) 1989-03-28 1991-03-05 The Wm. Wrigley Jr. Company Alitame stability in chewing gum by encapsulation
US5139794A (en) 1989-04-19 1992-08-18 Wm. Wrigley Jr. Company Use of encapsulated salts in chewing gum
US4978537A (en) 1989-04-19 1990-12-18 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
DK365389D0 (en) 1989-07-24 1989-07-24 Fertin Lab As ANTIFUNGAL CHEMICAL GUM PREPARATION
JPH0383913A (en) 1989-08-25 1991-04-09 Lotte Co Ltd Gum for preventing pyorrhea alveolaris
US5512306A (en) 1992-06-19 1996-04-30 Pharmica Ab Smoking substitute
US5045325A (en) 1990-09-26 1991-09-03 Warner-Lambert Company Continuous production of chewing gum using corotating twin screw extruder
US5488962A (en) 1990-10-10 1996-02-06 Perfetti, S.P.A. Chewing gum which is a substitute for tobacco smoke
JPH06102605B2 (en) 1990-11-19 1994-12-14 昭和薬品化工株式会社 Dental test agent composition
US5126151A (en) 1991-01-24 1992-06-30 Warner-Lambert Company Encapsulation matrix
DE4102629A1 (en) 1991-01-30 1992-08-06 Bayer Ag PHARMACEUTICAL RUBBER WITH ACETYL SALICYLIC ACID
US5179122A (en) 1991-02-11 1993-01-12 Eastman Kodak Company Nutritional supplement containing vitamin e
US5629013A (en) 1991-04-04 1997-05-13 The Procter & Gamble Company Chewable calcium carbonate antacid tablet compositions
US5244670A (en) 1991-04-04 1993-09-14 The Procter & Gamble Company Ingestible pharmaceutical compositions for treating upper gastrointestinal tract distress
US5380535A (en) 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
US5221698A (en) 1991-06-27 1993-06-22 The Regents Of The University Of Michigan Bioactive composition
ES2153362T3 (en) 1991-08-26 2001-03-01 Abbott Lab COMPOSITIONS AND PROCEDURES OF SUBLINGUAL OR BUCAL ADMINISTRATION OF THERAPEUTIC AGENTS.
WO1993011750A1 (en) 1991-12-17 1993-06-24 Fuisz Technologies Ltd. Ulcer prevention and treatment composition and method
GB9127150D0 (en) 1991-12-20 1992-02-19 Smithkline Beecham Plc Novel treatment
US5286500A (en) 1992-03-03 1994-02-15 Wm. Wrigley Jr. Company Wax-free chewing gum base
US5665406A (en) 1992-03-23 1997-09-09 Wm. Wrigley Jr. Company Polyol coated chewing gum having improved shelf life and method of making
ES2088632T3 (en) 1992-03-26 1996-08-16 Loders Croklaan Bv ECOLOGICAL CHEWING GUM BASE.
US5294449A (en) 1992-04-09 1994-03-15 Wm. Wrigley Jr. Company Composition of anti-cavity chewing gum and method of fighting tooth decay by using erythrose as anticaries agent
US5294433A (en) 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
US5286502A (en) * 1992-04-21 1994-02-15 Wm. Wrigley Jr. Company Use of edible film to prolong chewing gum shelf life
US5229137A (en) 1992-05-06 1993-07-20 Brigham And Women's Hospital, Inc. Methods and pharmaceutical compositions for treating episodic heartburn
GB9221414D0 (en) 1992-10-13 1992-11-25 Glaxo Group Ltd Pharmaceutical compositions
US5380530A (en) 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
US5496541C1 (en) 1993-01-19 2001-06-26 Squigle Inc Tasteful toothpaste and other dental products
US5378131A (en) 1993-02-18 1995-01-03 The Wm. Wrigley Jr. Company Chewing gum with dental health benefits employing calcium glycerophosphate
FR2706771A1 (en) 1993-06-21 1994-12-30 Pelletier Jacques Formula for the treatment of certain cancers.
US5340566A (en) 1993-08-09 1994-08-23 Colgate-Palmolive Company Method for preventing the progression of gingivitis
US5397580A (en) 1993-10-22 1995-03-14 Wm. Wrigley Jr. Company Continuous gum base manufacture using sequential mixers
US5543160A (en) 1994-09-13 1996-08-06 Wm. Wrigley Jr. Company Total chewing gum manufacture using high efficiency continuous mixing
US5419919A (en) 1993-10-22 1995-05-30 Wm. Wrigley Jr. Company Continuous gum base manufacture using paddle mixing
US5916606A (en) 1993-09-30 1999-06-29 Wm. Wrigley Jr. Company Chewing gum compositions containing erythritol and a moisture binding agent
US5494685A (en) 1994-05-17 1996-02-27 Wm. Wrigley Jr. Company Chewing gum with a rolling compound containing erythritol
DE4342568A1 (en) 1993-12-14 1994-06-01 Paul Ralf Peter Chewing gum contg. caffeine - used as substitute for coffee, tea, cola, etc. and to control fatigue and migraine
US5580590A (en) 1993-12-27 1996-12-03 The Wm. Wrigley Jr. Company Environmentally friendly chewing gum compositions containing elastic protein-based polymers and method of making it
JPH07184548A (en) 1993-12-28 1995-07-25 Meiji Seito Kk Component for oral cavity
US5585110A (en) 1994-03-28 1996-12-17 Kalili; Tom Chewing gum composition with fluoride and citric acid
US5834002A (en) 1994-05-02 1998-11-10 Josman Laboratories, Inc. Chewing gum containing colloidal bismuth subcitrate
US5536511A (en) 1994-05-06 1996-07-16 Wm. Wrigley Jr. Company Chewing gum pellet coated with a hard coating containing erythritol and xylitol
DE4415999A1 (en) 1994-05-06 1995-11-09 Bolder Arzneimittel Gmbh Gastric acid-binding chewing pastilles
EP0766646B1 (en) 1994-05-10 1998-04-15 Shell Internationale Researchmaatschappij B.V. Process for preparing a large pore molecular sieve
FR2719999B1 (en) 1994-05-17 1996-08-02 Georges Serge Grimberg Pharmaceutical composition based on guar gum and a neutralizing antacid, to which can be added a series of therapeutic active ingredients.
EP0685164A1 (en) 1994-06-03 1995-12-06 Asama Chemical Co., Ltd. Food quality improver
KR960006319B1 (en) 1994-06-30 1996-05-13 이승우 Chewing gum with pilocarpine
US5582855A (en) 1994-07-01 1996-12-10 Fuisz Technologies Ltd. Flash flow formed solloid delivery systems
IT1274034B (en) 1994-07-26 1997-07-14 Applied Pharma Res PHARMACEUTICAL COMPOSITIONS BASED ON RUBBER TO BE CHEWED AND PROCEDURE FOR THEIR PREPARATION
US5554380A (en) 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
US5456677A (en) 1994-08-22 1995-10-10 Spector; John E. Method for oral spray administration of caffeine
US5576344A (en) 1994-08-30 1996-11-19 American Home Products Corporation Process for reducing the adverse taste and malodor associated with H2 -antagonists
JP2927556B2 (en) 1994-09-13 1999-07-28 ダブリューエム リグリー ジュニア カンパニー Manufacturing method of gum base
WO1996015768A1 (en) 1994-11-18 1996-05-30 The Procter & Gamble Company Oral compositions
US5744164A (en) 1994-12-16 1998-04-28 Nestec S.A. Sustained release microparticulate caffeine formulation
US5601858A (en) 1994-12-29 1997-02-11 Warner-Lambert Company Non-stick chewing gum
US5534272A (en) 1995-01-03 1996-07-09 Bernstein Brothers Marketing Corp. Appetite suppressant chewing gum containing chromic picolinate
IL116674A (en) 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
FR2729967A1 (en) 1995-01-30 1996-08-02 Oreal COMPOSITIONS BASED ON AN ABRASIVE SYSTEM AND A SURFACE-ACTIVE SYSTEM
US5569477A (en) 1995-04-28 1996-10-29 Mccready Consumer Products, Inc. Chewing gum containing vitamins or other active materials
AU2814995A (en) 1995-05-26 1996-12-11 Angelo A. Caputo Chewing gum with fluoride and citric acid
US5854267A (en) 1995-06-02 1998-12-29 Merck & Co., Inc. Method for preventing heartburn
US5607697A (en) 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
US5665386A (en) 1995-06-07 1997-09-09 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5716928A (en) 1995-06-07 1998-02-10 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5645853A (en) 1995-08-08 1997-07-08 Enamelon Inc. Chewing gum compositions and the use thereof for remineralization of lesions in teeth
DE19529862A1 (en) 1995-08-14 1997-02-20 Rhone Poulenc Rorer Gmbh Pharmaceutical preparation for oral use
US5618517A (en) 1995-10-03 1997-04-08 Church & Dwight Co., Inc. Chewing gum product with dental care benefits
US5702687A (en) 1995-10-03 1997-12-30 Church & Dwight Co., Inc. Chewing gum product with plaque-inhibiting benefits
US5693334A (en) 1995-10-05 1997-12-02 Church & Dwight Co., Inc. Chewing gum product with dental health benefits
EP0784933A3 (en) 1995-10-16 1997-11-26 Leaf, Inc. Extended release of additives in comestible products
WO1997019699A1 (en) 1995-11-27 1997-06-05 Yamanouchi Pharmaceutical Co., Ltd. Drug composition
US5629035A (en) 1995-12-18 1997-05-13 Church & Dwight Co., Inc. Chewing gum product with encapsulated bicarbonate and flavorant ingredients
US6066342A (en) 1995-12-22 2000-05-23 Tamer International, Ltd. Antacid composition
US5889028A (en) 1996-02-09 1999-03-30 Mayo Foundation For Medical Education And Research Colonic delivery of nicotine to treat inflammatory bowel disease
US5736175A (en) 1996-02-28 1998-04-07 Nabisco Technology Co. Chewing gums containing plaque disrupting ingredients and method for preparing it
US5912007A (en) 1996-02-29 1999-06-15 Warner-Lambert Company Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same
US5846557A (en) 1996-03-20 1998-12-08 Cumberland Packing Corporation Chewing gum containing cough suppressing agent
US5866179A (en) 1996-05-03 1999-02-02 Avant-Garde Technologies & Products S.A. Medicated chewing gum and a process for preparation thereof
US5776956A (en) 1996-07-30 1998-07-07 Lectec Corporation Use of cotinine in treating psychiatric disorders
US5877173A (en) 1996-08-28 1999-03-02 Washington University Preventing neuronal degeneration in Alzheimer's disease
US5989588A (en) 1996-10-04 1999-11-23 Merck & Co., Inc. Methods and compositions for preventing and treating heartburn
US5882702A (en) 1996-10-07 1999-03-16 Warner-Lambert Company Process for the formation of plasticized proteinaceous materials and compositions containing the same
US5897891A (en) 1996-11-18 1999-04-27 Godfrey; John C. Flavorful zinc compositions for oral use incorporating copper
US6165516A (en) 1996-11-27 2000-12-26 Wm. Wrigley Jr. Company Method of controlling release of caffeine in chewing gum
WO2000035296A1 (en) * 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Improved release of medicament active agents from a chewing gum coating
US5980955A (en) 1996-12-30 1999-11-09 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US5753255A (en) 1997-02-11 1998-05-19 Chavkin; Leonard Chewable molded tablet containing medicinally active substances
US5958472A (en) 1997-02-26 1999-09-28 Warner-Lambert Company Crunchy chewing gum and process for making
US5824291A (en) 1997-06-30 1998-10-20 Media Group Chewing gum containing a teeth whitening agent
US5958380A (en) 1997-07-07 1999-09-28 Enamelon, Inc. Chewing gum products and the use thereof for remineralizing subsurface dental lesions and for mineralizing exposed dentinal tubules
US5858383A (en) 1997-08-11 1999-01-12 Summers Laboratories, Inc. Methods and compositions for topical treatment of ectoparasites
US5900230A (en) 1997-08-18 1999-05-04 Squigle, Inc. Dental products to treat and prevent periodontal disease
JPH1168559A (en) 1997-08-20 1999-03-09 Nec Corp Phase-locked loop circuit
US6221402B1 (en) * 1997-11-20 2001-04-24 Pfizer Inc. Rapidly releasing and taste-masking pharmaceutical dosage form
US5922346A (en) 1997-12-01 1999-07-13 Thione International, Inc. Antioxidant preparation
US5928664A (en) 1998-02-11 1999-07-27 Fuisz Technologies Ltd. Consumable gummy delivery system
US6200604B1 (en) 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
US6024988A (en) 1998-06-01 2000-02-15 Wm. Wrigley Jr. Company Caffeine chewing gum
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
CA2357923C (en) 1998-12-30 2005-03-15 David G. Barkalow Coating process applying powder and suspension syrup
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6355265B1 (en) 1999-04-06 2002-03-12 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
US6322806B1 (en) 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
US6428769B1 (en) * 1999-05-04 2002-08-06 Aradigm Corporation Acute testosterone administration
US6350480B1 (en) 1999-12-30 2002-02-26 Wm. Wrigley Jr. Company Chewing gum product including a hydrophilic gum base and method of producing
WO2002013781A1 (en) * 2000-08-14 2002-02-21 Fertin Pharma A/S Method for preparation of chewing gum with customer acceptable taste
US20020022057A1 (en) 2000-08-17 2002-02-21 Battey Alyce S. Oral delivery of pharmaceuticals via encapsulation
EP1217109A3 (en) 2000-12-22 2003-04-02 Maschinenfabrik Rieter Ag Spinning device

Also Published As

Publication number Publication date
WO2002041840A2 (en) 2002-05-30
US20020012633A1 (en) 2002-01-31
EP1408933A2 (en) 2004-04-21
US6531114B1 (en) 2003-03-11
EP1408933A4 (en) 2005-08-31
US6592850B2 (en) 2003-07-15
WO2002041840A3 (en) 2003-08-14

Similar Documents

Publication Publication Date Title
AU2002236566A1 (en) Sildenafil citrate chewing gum formulations and methods of using the same
AU2001268743A1 (en) Oral care compositions comprising chlorite and methods
DZ3307A1 (en) Stain removing chewing gum compositions and confectionery compositions, and methods of making and using the same
PL367344A1 (en) Stain removing chewing gum and confectionery compositions, and methods of making and using the same
PL363300A1 (en) Chewing gums and related products that provide breath freshening characteristics
AU2294301A (en) Controlled release perillartine in chewing gum
CA2422014A1 (en) Chewing gum formulations including encapsulated aspartame and sodium pyrophosphate
AU2003298583A1 (en) Chewing gum formulation and method of making the same
AU2633900A (en) Oral care chewing gums and confections
AU2001272314A1 (en) Oral formulations for localized colonic release and the method of preparation thereof
AU2564399A (en) Isoflavanoid formulations for oral administration
AU2003278604A1 (en) Oral preparation and chewing gum
AU2001288938A1 (en) Edible candy compositions and methods of using the same
AU2001253137A1 (en) Composition and method for promoting oral health
AU2362701A (en) Fragrance or flavor formulation
AU1607601A (en) Mint flavor and aroma compositions
AU2000278470A1 (en) Coated chewing gum
AU2002216736A1 (en) Dental etch with improved flavor
AU2001233086A1 (en) Ceramidase compositions and methods based thereon
AU6593100A (en) Interdental brush and interdental brush set
AU2003263895A1 (en) Contraceptive methods and formulations
AU3478001A (en) Chewing gum compositions
AU7995700A (en) Improved environmentally friendly gum bases and chewing gums including same
AU2002211147A1 (en) Apparatus for making dental inlays and the like
AU2002351859A1 (en) Chewing gums and process for the manufacture thereof