AU2002231886A1 - Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds - Google Patents

Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds

Info

Publication number
AU2002231886A1
AU2002231886A1 AU2002231886A AU2002231886A AU2002231886A1 AU 2002231886 A1 AU2002231886 A1 AU 2002231886A1 AU 2002231886 A AU2002231886 A AU 2002231886A AU 2002231886 A AU2002231886 A AU 2002231886A AU 2002231886 A1 AU2002231886 A1 AU 2002231886A1
Authority
AU
Australia
Prior art keywords
compounds
azepane
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002231886A
Inventor
Patrick Casara
Gilbert Dorey
Jean-Luc Fauchere
Nicolas Guilbaud
John Hickman
Thierry Le Diguarher
Jean-Claude Ortuno
Alain Pierre
Gordon Tucker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Publication of AU2002231886A1 publication Critical patent/AU2002231886A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2002231886A 2001-01-18 2002-01-16 Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds Abandoned AU2002231886A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0100638A FR2819511A1 (en) 2001-01-18 2001-01-18 New N-substituted azepane or azepanone derivatives, are selective farnesyl transferase inhibitors useful for treating cancer diseases, restenosis or type I neurofibromatosis
FR01/00638 2001-01-18
PCT/FR2002/000147 WO2002057223A2 (en) 2001-01-18 2002-01-16 Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds

Publications (1)

Publication Number Publication Date
AU2002231886A1 true AU2002231886A1 (en) 2002-07-30

Family

ID=8858952

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002231886A Abandoned AU2002231886A1 (en) 2001-01-18 2002-01-16 Compounds azepane, preparation method therefor and pharmaceutical compositions containing said compounds

Country Status (4)

Country Link
AR (1) AR034287A1 (en)
AU (1) AU2002231886A1 (en)
FR (1) FR2819511A1 (en)
WO (1) WO2002057223A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003284596A1 (en) * 2002-11-22 2004-06-18 Takeda Pharmaceutical Company Limited Imidazole derivative, process for producing the same, and use
JP4932135B2 (en) * 2002-11-22 2012-05-16 武田薬品工業株式会社 Imidazole derivatives, their production and use
TWI396686B (en) 2004-05-21 2013-05-21 Takeda Pharmaceutical Cyclic amide derivative, and its production and use
ITTO20130816A1 (en) * 2013-10-09 2015-04-10 Fond Istituto Italiano Di Tecnologia REV-ERB ANTARONISTS DIARYLALCHYLAMINES AND THEIR USE AS DRUGS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02104572A (en) * 1988-10-13 1990-04-17 Dainippon Pharmaceut Co Ltd Benzoic acid amide derivative
GB9026256D0 (en) * 1990-12-03 1991-01-16 Fujisawa Pharmaceutical Co Hexahydroazepine derivatives
CA2249641A1 (en) * 1996-04-03 1997-10-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5922883A (en) * 1996-04-03 1999-07-13 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP2000507595A (en) * 1996-04-03 2000-06-20 メルク エンド カンパニー インコーポレーテッド Inhibitors of farnesyl protein transferase
JP2001519766A (en) * 1996-04-03 2001-10-23 メルク エンド カンパニー インコーポレーテッド Inhibitors of farnesyl protein transferase
EP1137412A4 (en) * 1998-12-11 2002-04-03 American Biogenetic Sciences Substituted nitrogen heterocyclic compounds and therapeutic uses thereof

Also Published As

Publication number Publication date
FR2819511A1 (en) 2002-07-19
AR034287A1 (en) 2004-02-18
WO2002057223A3 (en) 2002-11-28
WO2002057223A2 (en) 2002-07-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase