AU2002230057A1 - Diphenyl ether derivatives and their uses as heparanase inhibitors - Google Patents

Diphenyl ether derivatives and their uses as heparanase inhibitors

Info

Publication number
AU2002230057A1
AU2002230057A1 AU2002230057A AU2002230057A AU2002230057A1 AU 2002230057 A1 AU2002230057 A1 AU 2002230057A1 AU 2002230057 A AU2002230057 A AU 2002230057A AU 2002230057 A AU2002230057 A AU 2002230057A AU 2002230057 A1 AU2002230057 A1 AU 2002230057A1
Authority
AU
Australia
Prior art keywords
diphenyl ether
ether derivatives
heparanase inhibitors
heparanase
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002230057A
Inventor
Maty Ayal-Hershkovitz
Neta Ilan
Avi Koller
Ofra Levy
Daphna Miron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insight Strategy and Marketing Ltd
Original Assignee
Insight Strategy and Marketing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insight Strategy and Marketing Ltd filed Critical Insight Strategy and Marketing Ltd
Publication of AU2002230057A1 publication Critical patent/AU2002230057A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
AU2002230057A 2001-01-29 2002-01-29 Diphenyl ether derivatives and their uses as heparanase inhibitors Abandoned AU2002230057A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26430501P 2001-01-29 2001-01-29
US60/264,305 2001-01-29
PCT/IL2002/000082 WO2002060375A2 (en) 2001-01-29 2002-01-29 Diphenyl ether derivatives and their uses as heparanase inhibitors

Publications (1)

Publication Number Publication Date
AU2002230057A1 true AU2002230057A1 (en) 2002-08-12

Family

ID=23005449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002230057A Abandoned AU2002230057A1 (en) 2001-01-29 2002-01-29 Diphenyl ether derivatives and their uses as heparanase inhibitors

Country Status (2)

Country Link
AU (1) AU2002230057A1 (en)
WO (1) WO2002060375A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8138265B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8137688B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6979750B1 (en) 2003-04-18 2005-12-27 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US7321065B2 (en) 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
JP2007508382A (en) * 2003-10-14 2007-04-05 イーライ リリー アンド カンパニー Phenoxyether derivatives as PPAR modulators
CA2555313A1 (en) * 2004-02-06 2005-08-18 Insight Biopharmaceuticals Ltd Heparanase inhibitors and uses thereof
JP5404406B2 (en) * 2006-10-20 2014-01-29 ジ オーストラリアン ナショナル ユニバーシティ Inhibition of extracellular matrix degradation
ES2534589T3 (en) 2007-04-13 2015-04-24 Southern Research Institute Clomipramine as an antiangiogenic agent
EP2249891B1 (en) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molecular enhancement of extracellular matrix and methods of use
EP2300042A4 (en) 2008-04-30 2012-05-02 Cleveland Clinic Foundation Compositions and methods to treat urinary incontinence
BR112019012045A2 (en) 2016-12-13 2020-08-18 Beta Therapeutics Pty Ltd heparanase inhibitors and their use
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
EP3381906A1 (en) * 2017-03-27 2018-10-03 Leadiant Biosciences SA Compounds for use as heparanase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2319174A1 (en) * 1998-06-08 1999-12-16 Advanced Medicine, Inc. Novel therapeutic agents that modulate 5-ht receptors

Also Published As

Publication number Publication date
WO2002060375A2 (en) 2002-08-08
WO2002060375A3 (en) 2003-10-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase