AU2002224214A1 - Mechanical connections in particular for small blood vessels - Google Patents
Mechanical connections in particular for small blood vesselsInfo
- Publication number
- AU2002224214A1 AU2002224214A1 AU2002224214A AU2002224214A AU2002224214A1 AU 2002224214 A1 AU2002224214 A1 AU 2002224214A1 AU 2002224214 A AU2002224214 A AU 2002224214A AU 2002224214 A AU2002224214 A AU 2002224214A AU 2002224214 A1 AU2002224214 A1 AU 2002224214A1
- Authority
- AU
- Australia
- Prior art keywords
- connector
- applicator
- annular member
- staple
- elements
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
Connector, applicator and method for mechanically connecting hollow structures, in particular small blood vessels, as well as auxiliary devices
The present invention relates to a connector and applicator for mechanically connecting hollow structures, in particular small blood vessels, through so called anastomoses. Such means may for example be used when making a bypass past narrowings or occlusions of arteries caused by arteriosclerosis .
One such connector and applicator are known from O-A- 99/21491 of applicants. This document discloses several embodiments of connectors which are made up of an annular member and circumferentially spaced joining means for holding the vessel walls together in order to make the joint between the vessels . The connectors as disclosed are suitable both for end-to-side and side-to-side anastomoses.
The object of the present invention is to further improve the connector and applicator for making mechanical connections between hollow structures.
To obtain this object, the present invention provides a connector for mechanically connecting hollow structures, in particular small vessels, comprising: an annular member of deformable material, said member having a center line and being adapted to be permanently- deformed by expansion from a first size in a starting position in which it is delivered to a desired anastomoses site, to a second, larger size in a joining position in which it connects the hollow structures, and circumferentially spaced means for joining abutting walls of the hollow structures together, said means including staple-like elements being adapted to be permanently deformed from a starting position in which the connector is delivered to a desired site, to a joining position in which they engage the hollow structures to connect them, said staple-like elements having at least two free ends and being attached to the annular
member between its free ends and being tapered from the annular member towards their free ends .
This connector according to the invention has various advantages. The expandability of the annular member is advantageous because, as a result, the size of the connector is small during delivery, while the expansion, which results in a radially outward movement of the staple-like elements before or during deformation into their joining position, helps to predictably position the tissue of the vessel walls between the free ends of the joining means. Moreover, the size of the annular member can be adapted to the size of the vessels on the site of the anastomosis. The staple-like elements are very suitable for holding together adjacent vessel walls of the vessels to be connected. Due to the tapering, the predictability of the plastic deformation, which is required to close the staples, is improved. If the staples should be curved according to a certain curvature, the deformation will start at the tips and progress towards the annular member, which leads to a predictable deformation. The tapering can take various forms. The staple-like elements may for example be conically or wedge-shaped towards the free ends. Preferably, the radial thickness of the staple-like elements is diminished towards the respective free ends, but also the width may be tapered.
In a preferred embodiment, the staple-like elements are substantially straight and parallel to the center line of the annular member. With this arrangement, the connector can have a minimum diameter which facilitates easy handling during an operation. From this straight starting position, the staplelike elements can be deformed either to a C-shape to form a perfect or overlapping circle, or to a B-shape or an overlapping B-shape.
In order to further increase the predictability of the deformation phase of the staple-like elements, the staple-like elements may be provided with extreme tips which are preformed into the anticipated curve of the deformation to the joining position.
It is not necessary that the portions of the staplelike elements on either side of the point of attachments to the
annular member are mirror shaped. The length, thickness and slope towards the free ends can be varied to accommodate required bending characteristics or vessel wall thicknesses.
It is preferred to make the connector according to the invention from one piece of material, preferably metal, for example stainless steel 316L or titanium. Connectors which are sufficiently small for use in coronary artery bypass surgery can be manufactured from one piece of metal by using a combination of cutting with a lathe or rolling and subsequently using laser techniques or electric erosion techniques. In this way, the connector is made directly in 3D. Alternatively, 2D- techniques like photo-etching or electroplating can be used to make 2D pieces out of thin, flat material. These can be converted into 3D, either by forcing a 2D shape into 3D, or by bending and welding together the beginning and end of the 2D shap .
An easily expandable annular member is obtained if the annular member is made up from a continuous elongated piece of material having a sinusoidal pattern meandering about a circle line through the annular member. In this case, the staple-like elements are preferably formed at an apex of the sinusoidal pattern.
In order to increase the maximum size of the annular member in the joining position, it could be advantageous to have the main plane of the annular member at an angle to the center line of the annular member.
Due to this feature, the orifice area of the anastomosis can be increased without increasing the size of the connector and applicator, which is limited by the diameter of the hollow structures through which the applicator is inserted. The above feature results in an elliptical anastomosis with an increased orifice area as compared to a circular anastomosis, while the size of the applicator can remain unchanged. In case the main plane of the annular member is at an angle of for example 45°, the area is increased by a factor D2 = 1.41. Practically the staple-like elements of the connector will remain parallel to the center line of the applicator and connector.
The present invention also includes an applicator for delivering and deploying a connector for mechanically connecting hollow structures, comprising: a shank-like element; a head formed at a distal end of the shank-like element, said head being adjustable in such a manner that the annular member and the staple-like elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, said head including an inner member and an outer member which are longitudinally slidable and include longitudinally opposite anvil formations which are movable to and from upon relative sliding movements of the inner and outer members in order to deform the staple-like elements to their joining position; wherein both the inner and outer members are_ expandable to deform the connector to the joining position.
Due to the expandability of both the inner and outer members, it is possible to minimize the radial dimensions of the applicator. It is now possible to make the head of the applicator smaller than the radial size of the connector in the joining position, since the outer member of the head of the applicator is enabled to expand together with the connector. A simple manner to obtain the expandability of the inner and outer members is to slit or cut them in axial direction. Preferably, the outer member includes at least first slits and second slits, said first slits are arranged at an end of the outer member which forms part of the head and extends between the anvil formations, said second slits being spaced from said end of the outer member, and alternate with the first slits and are configured in overlapping arrangement.
Due to this configuration of the slits or cuts, the radial as well as the tangential stiffness of the delicate material between the slits is increased. This further assists in diminishing the dimensions of the head of the applicator. Another advantageous feature to minimize the radial dimensions of the head is the feature that the anvil formations, on their sides facing each other, have curved
surfaces dictating the deformation of the staple-like elements, said curved surfaces being formed to such an extent that they terminate at an angle to the longitudinal axis of the head which is slightly beyond 90°, for example 9l°-120°. These "low profile" anvil formations make the applicator head as slender as possible, but nonetheless allow for a predictable bending of the staple-like elements of the connector.
An alternative applicator according to the invention comprises a shank-like element, and a head formed at a distal end of the shank-like element, said head being adjustable in such a manner that the annular member and the staple-like elements of the connector are deformed from the starting position to the joining position when said adjusting takes place. The head includes an inner member and an outer member which are longitudinally slidable and include longitudinally opposite anvil formations which are movable to and from upon relative sliding movements of the inner and outer members in order to deform the staple-like elements to their joining position. The head further includes an expansion member comprising wedges adapted to slide underneath the annular membe .
In this embodiment of the applicator according to the invention, the expansion of the annular member of the connector is effected by the wedges of the expansion member which slide underneath the annular member and thereby urging the annular member outwardly.
One way of enabling the wedges to slide underneath the annular member is to make the expansion member slidable relative to the inner and outer members, and in this embodiment it is advantageous if the wedges are interleaved with the anvil formations, since the head of the applicator can then be made as small as possible .
In this embodiment of the applicator, the simplest design thereof is obtained if the staple-like elements are first deformed to their joining position, whereafter the annular member is expanded by the wedges of the expansion member. In that case it is not necessary to make the outer
member expandable and in a preferred embodiment it is even possible to expand the annular member of the connector and remove it from the head of the applicator in distal direction over the anvil formations of the inner member in a continued operation.
In another embodiment of the applicator according to the invention, the head includes not only an anastomosis portion which is adjustable in such a manner that the annular member and the joining elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, but also a punching portion distally of the anastomosis portion and including two relatively movable parts configured to cause a punching action on a wall of the hollow structure and to catch or trap a punched-out part of said wall.
With such applicator it is possible to both, cut a hole in the vessel wall in order to enable the applicator to enter the vessel, and to perform the anastomosis with the same instrument. This simplifies the procedure and reduces time and cost.
The invention further includes a method of delivering and deploying a connector for mechanically connecting hollow structures. This method comprises the steps of: providing a connector for joining adjacent walls of the hollow structures, providing an applicator for said connector, said applicator including cutting means, making an arteriotomy in the wall of one of the hollow structures, inserting the cutting means of the applicator partly into said one of the hollow structures through the arteriotomy, so as to cut a hole in the wall, advancing the applicator up to a desired position, deploying the connector by means of the applicator so as to connect the walls of the hollow structures.
The invention further includes a deforming instrument to reduce the dimensions of an annular member of a connector for mechanically connecting hollow structures into an oval
shape, in situ. This instrument is constructed like a forceps having two opposite pinching members to engage the outer side of the annular member and is provided with a stop to limit movement of the pinching members when applying a deforming force in the direction of the desired reduced dimension of the annular member.
The invention also includes a punch for punching out an anastomosis made by a connector having an annular member. Said punch comprises an expandable inner gripping means which is insertable in the connector. An outer cutting tube has a sharp punching edge adapted to fit closely to the connector. The inner diameter of the cutting tube is equal to or slightly larger than the largest diameter of the connector. The cutting tube is slidable with respect to the gripping means to punch out the anastomosis when the connector is held by the gripping means .
The invention will further be described with reference to the drawings showing embodiments of the invention by way of example . Fig. 1 is a perspective view of an embodiment of the connector according to the invention.
Fig. 2 is a view of the connector of fig. 1 in radial direction.
Fig. 3 is a view of the connector of fig. 1 in axial direction.
Fig. 4 is a perspective view of an applicator for use with the connector of figs. 1-3, on a smaller scale.
Fig. 5 is a front view of the applicator of fig. 4.
Fig. 6 is a sectional view of the applicator of fig. 4, along the plane VI-VI in fig. 5.
Fig. 7 is an axial view of the outer member of the applicator of fig. 4, on a larger scale.
Fig. 8 is a sectional view of the outer member of fig. 7 along the plane VIII-VIII. Fig. 9 is an axial view of the inner member of the applicator of fig. 4, on a larger scale.
Fig. 10 is a sectional view of the inner member of fig. 9, taken along the line X-X.
Fig. 11 is a very schematic perspective view of members forming the head of an alternative embodiment of the applicator according to the invention.
Fig. 12 is a sectional view along the line XII-XII in fig. 11.
Figs. 13A-13C are longitudinal sectional views of the applicator head of fig. 11, in three different positions during deployment of the connector.
Fig. 14 is a very schematic side view of an alternative embodiment of the connector according to the invention.
Fig. 15 is a very schematic side view of the head of an applicator for delivering and deploying the connector of Fig. 14. Fig. 16 is a very schematic, partly cut-away side view of the head of a further embodiment of an applicator .according to the invention.
Fig. 17 is an enlarged longitudinal sectional view of the head of an applicator which is slightly modified with respect to the applicator of Fig. 4 - 10.
Fig. 18 is an enlarged perspective view of the head of an expansion core for use in the applicator of Fig. 17.
Fig. 19 shows in an enlarged perspective view modified parts which may be used in the applicator of Fig. 17. Fig. 20 is a side view of the head of the expansion core of Fig. 18, provided with an insertion cone.
Fig. 21 is a sectional view of a hollow structure and the head of the expansion core after insertion into the hollow structure . Fig. 22 is a perspective view of two hollow structures to illustrate a phenomenon called seagulling.
Fig. 23 is a longitudinal sectional view of a deforming instrument for reducing the outer size of a connector for making an anastomosis . fig. 24A and 24B are two longitudinal sectional views of a punch for punching out an anastomosis made by a connector.
Figs. 1-3 show an embodiment of a connector for mechanically connecting hollow structures, in particular small
blood vessels, such as coronary arteries. The connector is specially designed for making a side-to-side anastomosis but may also be used or adapted to make other connections, for example an end-to-side anastomoses or other joints. The connector as shown comprises an annular member 1 and a plurality of joining means in the form of staple-like elements 2 spaced around the circumference of the annular member 1. The annular member and staple-like elements are preferably formed from one piece of material, preferably metal such as stainless steel 316L or titanium.
The annular member as shown in figs. 1-3 comprises a continuous elongated element having a sinusoidal pattern meandering about a circle line through the annular member. The alternating waves 3 and 4 of the pattern have a different wave length in order to accommodate the staple-like elements 2 which are formed at each wave 4, at the apex thereof . The meandering pattern of the annular member 1 creates the expandability of the annular member by widening the meanders or waves of the pattern thereby increasing the diameter of the annular member 1. The deformation of the annular member 1 is plastically, so that the annular member 1 will retain its shape after expansion.
The configuration of the annular member 1 may vary within a broad range, including the length of the annular member 1. The term annular also covers tubular members. The staple-like elements 2 comprise two staple portions 5, 6 which extend from the point of attachment to the annular member 1 in opposite directions . In the embodiment shown, both staple portions 5, 6 are aligned and are substantially each other's mirror image, but it should be kept in mind that that need not be the case. Instead thereof, the length, thickness and slope towards the free ends of the staple portions 5 , 6 can be varied to accommodate required bending characteristics or vessel wall thicknesses . As is shown in figs. 1-3, in which the connector is shown in its starting position in which it is delivered to the anastomosis site, the staple-like elements are substantially straight and extend parallel to the center axis of the annular
member. The staple portions 5, 6 are slightly tapered towards their free ends, both in radial thickness and in circumferential width. The tapering is on the outer side of the staple portions 5, 6, whereas the radial inner side of the staple portions 5, 6 extends parallel to the center axis. The circumferential sides of the staple portions 5, 6 are inclined relative to a radial plane through the center of the staple portions 5, 6 such that the width of a staple-like element 2 is smaller on the radial inner side than on the radial outer side . If desired, the extreme tips of the staple portions 5, 6 may be preformed into the anticipated curve, to increase the predictability of the deformation of the staple portions 5, 6. The waves 3 may also be slightly tapered, i.e. having a diminishing thickness in axial direction in the same manner as the adjacent staple portions 5.
Figs. 4-10 show an embodiment of the applicator according to the invention. The applicator includes a main body 7, a grip 8 extending downwardly therefrom on the rear end, a control lever 9 pivotally connected to the front end of the main body 7 and extending downwardly, and a stroke limiter 10 pivotally attached to the lower end of the control lever 9 and slidably connected to the lower end of the grip 8. A pin slot connection 11 between the stroke limiter 10 and the grip 8 determines the maximum stroke of the control lever 10. The control arm may be locked in position by locking the stroke limiter 10 to the grip 8. The control lever 9 is pivotally connected to an intermediate pivot 12 in order to provide a long lever arm 13 and a short lever arm 14. The end of the short lever arm 14 is pivotally connected to a sliding block 15, the sliding motion being guided and limited through a bolt 16.
Attached to the sliding block 15 is an outer tube member 17 and attached to the main body 7 is an inner tube member 18. The inner and outer members 17, 18 together form a shank-like element and on the free end thereof a head 20 adapted to accommodate a connector in order to deliver it to the anastomosis site and to deploy it into a joining position. Figs. 7 and 8/8a show the outer tube member 17 and figs. 9 and
10/lOa show the inner tube member 18 in more detail. Inside of the inner tube member is an expansion core connected to an expansion control means 22.
The outer member 17 is provided on its distal end with proximal anvil formations or anvils 23 having a curved surface 24 facing, in a assembled condition, corresponding curved surfaces 25 of distal anvil formations or anvils 26 provided on the distal end of the inner member 18. The number of distal and proximal anvils 23, 26 is equal to the number of staple-like elements 2 of each connector, in this case 8. The anvils 23, 26 are distributed around the circumference of the inner and outer members 17, 18 in the same manner as the staple-like elements on the connector, in this case equally spaced around the circumference. The inner member 18 is provided with a seat 27, proximal of the anvils 26, to accommodate the connector during delivery and in this starting position of the applicator and connector, the inner and outer members 17, 18 have such relative position that the connector is positioned between adjacent anvils 23 and 26 of the inner and outer members 17, 18, with each staple-like element 2 being aligned with respective anvils 23, 26.
In order to be able to expand the connector which is seated on the seat 27 of the inner member 18, this inner member is slitted with cuts or slits 28 extending from the distal end of the inner member 18 a distance in proximal direction. The length of the slits is such that the tongues left between the slits 28 may undergo a sufficient radial deflection to expand the connector to a sufficient extent. The length of the slits may for example be 5-10 times the diameter of the inner member 18. The lumen 29 through the inner tube member 18 has a flaired end part 30, in which the diameter of the lumen is increased in distal direction, for example at an angle of 30° to 45°. This end part 30 is adapted to accommodate the tapered end part of the expansion core 21, so that when the expansion core 21 is retracted in proximal direction by the expansion control means 22, the tapered end part urges the tongues between the slits 28 of the inner tube member 18 outwardly so that the connector present on the seat 27 is expanded.
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shape, ending in a sharp point. This configuration permits creating an arteriotomy, punching out a hole and securing the anastomosis with one instrument and requiring only one instrument insertion. To punch the hole this rounded front of the distal part 338 is inserted into the arteriotomy, subsequently this distal part 338 is pulled against the circular knife 341 of the proximal part 339. A circular piece of vessel wall is then cut out and remains trapped between and inside the distal and proximal parts 338, 339 which together enclose this vessel wall piece. This entrapment is important since loose tissue fragments can embolize.
Subsequently, the applicator is pushed further inwardly so that the anastomosis portion 336 is brought in line with the vessel walls to be joined. The expansion mechanism of the anastomosis portion 336 is activated by further retracting the core 340 and distal part 338 in order to push the expansion core 321 (formed on the proximal part 339) in proximal direction with respect to the anastomosis portion 336 so as to expand the seat 327 where the connector is positioned. The further operation of the applicator is similar to that of the embodiment of Figs. 4-10.
This embodiment has the unique feature of being capable to punch a hole and secure the anastomosis during one instrument insertion. Because it is not necessary to remove the applicator between these two manipulations, there is very limited blood loss and maximum control . This makes the applicator very suitable for making proximal anastomoses on the aorta in port access CABG.
Alternatively, the punch mechanism could be replaced by a single, linear knife, which makes a linear arteriotomy. The applicator is than advanced through this arteriotomy and deforms it to a more circular shape.
The punch mechanism could also be replaced by a simple, circular knife. A pointed wire with a simple retaining mechanism like a hook, extending distally to the circular knife would puncture the vessel wall before cutting and would hold the piece of vessel wall after cutting to prevent it from embolizing in the patient. The punch or cut mechanisms could
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radially pointing arms 54 of the U-shaped piece 53 have sufficient length to also embrace the legs of inner member 18. The U-shaped pieces 53 may be attached to an expandable ring or tubular element, like a meandering ring, to result in a single piece that provides guidance for keeping the proximal and distal anvils aligned.
In Fig. 20 and 21 it is shown that, for easy insertion, a separate nose 55 cone may be provided that is pivotally connected to the central expansion core 21 (Fig 20) . This can be achieved by connecting the nose cone 55 with a flexible thread or wire 56 to central expansion core 21. This results in an articulation of the nose-cone that is necessary to enable a position of 90° relative to the axis of the acceptor vessel during expansion and stapling of the anastomosis (Fig. 21) . Introduction may be done at 45°.
For proper introduction of the distal anvils_ 26 in the target vessel, optimal visualisation is necessary. In order to achieve this, the previously mounted donor vessel may be moved temporarily over the proximal anvils 23 to a location somewhere on the tapered end of outer member 17. With an unobstructed view, the connector then can be introduced into the target vessel . Once satisfied with the position, the donor vessel can be slid back to a position between the proximal and distal vessels, followed by expansion and closure of the joining means.
In the treatment of obstructive coronary artery disease, the connection between newly grafted donor vessels and the coronary artery downstream of its stenosis, where it is unobstructed again, should offer no obstruction to the bloodflow. In order to achieve this in the disclosed method, it is advantageous to construct anastomoses with an orifice area that is larger than the target vessel. In practice, the coronary artery, which is the target vessel is most often smaller than the donor vessel. In case of a circular or polygonal anastomosis, the construction of such an anastomosis is only achieved if the diameter of the anastomosis exceeds the transverse diameter of the target vessel. This oversizing of the anastomosis, while attractive with respect to the objective
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between the joining means, with a very sharp, modified punch 59 as shown in Fig. 24A and 24B. This also offers fresh, cleanly cut edges of the arteriotomy for a second try, if desired. The modified punch has an expandable gripping means 60 with small distal notches 61, which is inserted in the connector 1, after the donor vessel is longitudinally cut open. This expandable gripping means 60 can be realized by providing longitudinal slits in an inner member, much in the same way as in the applicator. Expansion is effected by pulling a conical core 62 element inside (Fig. 24B) . This expansion establishes a firm hold and centers the connector 1 in front of an outer cutting tube 63, which has a very sharp edge 64. The cutting tube 63 has an inner diameter which is equal to or slightly larger than the largest diameter of the connector 1, including its joining means. The cutting tube 63 is then moved into the anastomosis and the complete anastomosis is punched out and removed when the punch is withdrawn. The cutting tube 63 can be circular, or polygonal in order to fit the connector 1 as closely as possible. In case of a circular shape, the cutting tube 63 may be rotated relatively to the inner member 60 holding the connector 1 and tissue, in order to improve the cutting effect of the sharp edge 64.
From the foregoing it is clear that the present invention provides a connector, applicator and method for mechanically connecting small blood vessels and the like in a simple, reliable and efficient manner.
The invention is not restricted to the embodiments shown in the drawing and described herein before and can be varied within the scope of the accompanying claims.
Claims (45)
1. A connector for mechanically connecting hollow structures, in particular small vessels, comprising: an annular member of deformable material, said member having a center line and a main plane, and being adapted to be permanently deformed by expansion from a first size in a starting position in which it is delivered to a desired anastomosis site, to a second, larger size in a joining position in which it connects the hollow structures, circumferentially spaced means for joining abutting walls of the hollow structures together, said means including staple-like elements being adapted to be permanently deformed from a starting position in which the connector is delivered to a desired site, to a joining position in which they engage the hollow structures to connect them, said staple-like elements having at least two free ends and being attached to the annular member between its free ends and being tapered from the annular member towards their free ends.
2. The connector as claimed in claim 1, wherein at least the radial thickness of the staple-like elements is diminished towards the respective free ends.
3. The connector as claimed in claim 1 or 2 , wherein a center line of each of the staple-like elements is disposed substantially within a radial plane of the annular member.
4. The connector as claimed in claim 2, wherein the staple-like elements are substantially straight in their starting position.
5. The connector as claimed in claim 3 , wherein the staple-like elements have extreme tips which are preformed into the anticipated curve of the deformation to the joining position.
6. The connector as claimed in one of the preceding claims, wherein the connector is made from one piece of material .
7. The connector as claimed in one of the preceding claims, wherein parts of the staple-like elements on opposite sides of their point of attachment to the annular member are configured differently.
8. The connector as claimed in one of the preceding claims, wherein the annular member is made up from a continuous elongated piece of material having a sinusoidal pattern meandering about a circumferential line through the main plane of the annular member.
9. The connector as claimed in claim 8, wherein the staple-like elements are formed at an apex of the sinusoidal pattern.
10. The connector as claimed in one of the preceding claims, wherein the main plane is at an angle to the center line of the annular member different from 90°.
11. An applicator for delivering and deploying a connector for mechanically connecting hollow structures, said connector including an expandable annular member and a plurality of deformable staple-like elements spaced around the circumference of the annular member, comprising: a shank-like element; a head formed at a distal end of the shank-like element, said head being adjustable in such a manner that the annular member and the staple-like elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, said head including an inner member and an outer member which are longitudinally slidable and include longitudinally opposite anvil formations which are movable to and from upon relative sliding movements of the inner and outer members in order to deform the staple-like elements to their joining position; wherein both the inner and outer members are expandable to deform the connector to the joining position.
12. The applicator as claimed in claim 11, wherein both the inner member and the outer member is slitted in axial direction to allow expansion.
13. The applicator as claimed in claim 12, wherein the outer member includes at least first slits and second slits, said first slits are arranged at an end of the outer member which forms part of the head and extends between the anvil formations, said second slits being spaced from said end of the outer member, and alternate with the first slits and are configured in overlapping arrangement.
14. The applicator as claimed in claim 12 , adapted to expand the annular member and deform the staple-like elements in two steps, wherein the inner member is hollow and the applicator further comprises a tapered core member which is slidable through the inner member and is operatively connected to a control means to slide the core member into and out of the head to expand the inner and outer members.
15. The applicator as claimed in claim 14, wherein the core member and control means are used to control the relative movements of the inner and outer members as well.
16. The applicator as claimed in claim 11,, wherein the anvil formations, on their sides facing each other, have curved surfaces dictating the deformation of the staple-like elements, said curved surfaces are formed to such an extent that they terminate at an angle to the longitudinal axis of the head which is slightly beyond 90°, for example 91°-120°.
17. The applicator as claimed in claim 16, wherein the curved surface is shaped as a circular segment which is slightly larger than 90°.
18. The applicator as claimed in claim 11, including a grip for handling the applicator, said grip being attached to the proximal end of the shank-like element and including the control means for actuating at least the inner and outer members .
19. An applicator for delivering and deploying a connector for mechanically connecting hollow structures, said connector including an expandable annular member and a plurality of deformable staple-like elements spaced around the circumference of the annular member, comprising: a shank-like element; a head formed at a distal end of the shank-like element, said head being adjustable in such a manner that the annular member and the staple-like elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, said head including an inner member and an outer member which are longitudinally slidable and include longitudinally opposite anvil formations which are movable to and for upon relative sliding movements of the inner and outer members in order to deform the staple-like elements to their joining position; said head further including an expansion member comprising wedges adapted to slide underneath the annular member.
20. The applicator as claimed in claim 19, wherein the expansion member is slidable relative to the inner and outer members .
21. The applicator as claimed in claim 20, wherein the wedges are interleaved with the anvil formations.
22. The applicator as claimed in claim 20, wherein the inner member is adapted to support the annular member in its starting position.
23. The applicator as claimed in claim 20, further including control means adapted to first actuate the inner and outer member to deform the staple-like elements to the joining position, and then to actuate the expansion member in order to expand the annular member to the joining position.
24. The applicator as claimed in claim 20, wherein the anvil formations on the inner member have an outer dimension which is smaller than the maximum outer dimension of the expansion member, such that the connector can be removed from the applicator in the distal direction over the anvil formations on the inner member.
25. The applicator as claimed in claim 22, wherein the expansion member includes a tube-like member arranged around the outer member, said tube-like member having the wedges attached to its distal end, said wedges extending inwardly to the outer surface of the inner member.
26. The applicator as claimed in claim 25, wherein the outer member has indentations between the proximal anvil formations to accommodate the wedges in a starting position thereof .
27. The applicator as claimed in claim 11 or 19, wherein the shank-like element is rigid.
28. The applicator as claimed in claim 11 or 19, wherein the shank-like element is flexible.
29. An applicator for delivering and deploying a connector for mechanically connecting hollow structures, said connector including an expandable annular member and a plurality of deformable joining elements spaced around the circumference of the annular member, comprising: a shank-like element; a head formed at a distal end of the shank-like element, said head including an anastomosis portion which is adjustable in such a manner that the annular member and the joining elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, said head further including a punching portion distally of the anastomosis portion and including two relatively movable parts configured to cause a punching action on a wall of the hollow structure and to catch a punched-out part of said wall .
30. The applicator as claimed in claim 29, wherein the two parts of the punching portion are axially movable and include a distal part shaped to be inserted into an arteriotomy of the hollow structure, and a proximal part, said distal and proximal parts including cooperating knife members facing each other and adapted to catch the punched-out part between said distal and proximal part .
31. The applicator as claimed in claim 30, wherein the anastomosis portion and the puncture portion are supported by a core member extending through the head of the applicator.
32. The applicator as claimed in claim 29, wherein a distal front of the punching portion of the head comprises cutting means to cut an arteriotomy in one of the hollow structures.
33. A method of delivering and deploying a connector for mechanically connecting hollow structures, said method comprising the steps of : providing a connector for joining adjacent walls of the hollow structures, providing an applicator for said connector, said applicator including cutting means, making an arteriotomy in the wall of one of the hollow structures, inserting the cutting means of the applicator partly into said one of the hollow structures through the arteriotomy, so as to cut a hole in the wall, advancing the applicator up to a desired position, deploying the connector by means of the applicator so as to connect the walls of the hollow structures .
34. The method as claimed in claim 32, wherein the arteriotomy is made by a second cutting means provided on a distal front of the applicator.
35. An applicator for delivering and deploying a connector for mechanically connecting hollow structures, said connector including an expandable annular member and a plurality of deformable joining elements spaced around the circumference of the annular member, comprising: a shank-like element; and a head formed at a distal end of the shank-like element, said head including an anastomosis portion which is adjustable in such a manner that the annular member and the joining elements of the connector are deformed from the starting position to the joining position when said adjusting takes place, said head having a distal front which comprises cutting means to cut an arteriotomy in one of the hollow structures .
36. A connector for mechanically connecting hollow structures, in particular small vessels, comprising: an annular member of deformable material, said member having a center line and a main plane, and being adapted to be permanently deformed by expansion from a first size in a starting position in which it is delivered to a desired anastomosis site, to a second, larger size in a joining position in which it connects the hollow structures, circumferentially spaced means for joining abutting walls of the hollow structures together, said means including staple-like elements being adapted to be permanently deformed from a starting position in which the connector is delivered to a desired site, to a joining position in which they engage the hollow structures to connect them, wherein the main plane through the annular member and the center line thereof are at an angle to each other.
37. A connector for mechanically connecting hollow structures, in particular small vessels, comprising: an annular or tubular member of deformable material, said member being adapted to be permanently deformed from a first size in a starting position in which it is delivered to a desired site, to a second, larger size in a joining position in which it connects the hollow structures, circumferentially spaced means for joining abutting walls of the hollow structures together, said means including staple-like elements being adapted to be permanently deformed from a starting position in which the connector is delivered to a desired site, to a joining position in which they engage the hollow structures to connect them, said staple-like elements being attached to the annular member near their center and extend in a direction parallel to the center line of the annular member.
38. The applicator as claimed in claim 11, wherein the outer surface of the outer member is sligthly tapering towards the anvil formations thereof .
39. The applicator as claimed in claim 14, wherein the core member has guide members to guide parts of the inner members carrying the anvil formations during expansion.
40. The applicator as claimed in claim 14, wherein the applicator comprises U-shaped members that fit radially around axial legs formed in the outer member by axial slits, said U- shaped members being positioned proximally of the anvil formations on the outer member.
41. The applicator as claimed in claim 14, wherein the core member comprises a separate nose cone that is pivotally connected thereto, for example with a flexible thread or wire.
42. System for for mechanically connecting hollow structures, in particular small blood vessels, including the applicator of claim 11, and a connector including an expandable annular member and a plurality of deformable staple-like elements spaced around the circumference of the annular member, wherein the outer diameter of the anvil formations of the inner member in the unexpanded state is smaller than the inner diameter of the annular member of the connector in expanded state.
43. Deforming instrument to reduce the dimensions of an annular member of a connector for mechanically connecting hollow structures into an oval shape, constructed like a forceps having two opposite pinching members to engage the outer side of the annular member and being provided with a stop to limit movement of the pinching members when applying a deforming force in the direction of the desired reduced dimension of the annular member.
44. A punch for punching out an anastomosis made by a connector having an annular member, said punch comprising an expandable inner gripping means which is insertable in the connector, and an outer cutting tube having a sharp punching edge adapted to fit closely to the connector, said cutting tube having an inner diameter which is equal to or slightly larger than the largest diameter of the connector, and being slidable with respect to the gripping means to punch out the anastomosis when the connector is held by the gripping means.
45. Method of removing an anastomosis in hollow structures made by a connector having an annular member, comprising the steps of inserting a punch to the location of the anastomosis, gripping the annular member from the inside, moving a cutting tube towards the connector and allowing a sharp punching edge thereof to punch a hole into the hollow structure, whereafter the punch is withdrawn.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US09/708,617 US6966917B1 (en) | 2000-11-09 | 2000-11-09 | Deformable connector for mechanically connecting hollow structures |
US09/708,617 | 2000-11-09 | ||
PCT/NL2001/000815 WO2002038055A2 (en) | 2000-11-09 | 2001-11-09 | Mechanical connections in particular for small blood vessels |
Publications (2)
Publication Number | Publication Date |
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AU2002224214A1 true AU2002224214A1 (en) | 2002-07-25 |
AU2002224214B2 AU2002224214B2 (en) | 2006-07-20 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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AU2421402A Pending AU2421402A (en) | 2000-11-09 | 2001-11-09 | Connector, applicator and method for mechanically connecting hollow structures, in particular small blood vessels, as well as auxiliary devices |
AU2002224214A Ceased AU2002224214B2 (en) | 2000-11-09 | 2001-11-09 | Mechanical connections in particular for small blood vessels |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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AU2421402A Pending AU2421402A (en) | 2000-11-09 | 2001-11-09 | Connector, applicator and method for mechanically connecting hollow structures, in particular small blood vessels, as well as auxiliary devices |
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US (3) | US6966917B1 (en) |
EP (3) | EP1683491B1 (en) |
JP (2) | JP4167060B2 (en) |
AT (2) | ATE405215T1 (en) |
AU (2) | AU2421402A (en) |
CA (1) | CA2436835C (en) |
DE (2) | DE60135510D1 (en) |
DK (1) | DK1683491T3 (en) |
ES (2) | ES2261514T3 (en) |
IL (1) | IL155764A0 (en) |
PT (1) | PT1683491E (en) |
WO (1) | WO2002038055A2 (en) |
Families Citing this family (164)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1007349C2 (en) | 1997-10-24 | 1999-04-27 | Suyker Wilhelmus Joseph Leonardus | System for the mechanical production of anastomoses between hollow structures; as well as device and applicator for use therewith. |
US8758400B2 (en) | 2000-01-05 | 2014-06-24 | Integrated Vascular Systems, Inc. | Closure system and methods of use |
US9579091B2 (en) | 2000-01-05 | 2017-02-28 | Integrated Vascular Systems, Inc. | Closure system and methods of use |
US6391048B1 (en) | 2000-01-05 | 2002-05-21 | Integrated Vascular Systems, Inc. | Integrated vascular device with puncture site closure component and sealant and methods of use |
EP1294288B1 (en) | 2000-09-08 | 2011-03-30 | Abbott Vascular Inc. | Surgical staple |
US6626918B1 (en) | 2000-10-06 | 2003-09-30 | Medical Technology Group | Apparatus and methods for positioning a vascular sheath |
US6966917B1 (en) * | 2000-11-09 | 2005-11-22 | Innovation Interventional Technologies B.V. | Deformable connector for mechanically connecting hollow structures |
US6869437B1 (en) * | 2000-11-13 | 2005-03-22 | Cardica, Inc. | Method and system for performing closed-chest bypass |
US8690910B2 (en) | 2000-12-07 | 2014-04-08 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US6623510B2 (en) | 2000-12-07 | 2003-09-23 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US7905900B2 (en) | 2003-01-30 | 2011-03-15 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US6985235B2 (en) * | 2001-08-30 | 2006-01-10 | Micron Optics, Inc. | Cascaded fiber fabry-perot filters |
US8012164B1 (en) | 2002-01-22 | 2011-09-06 | Cardica, Inc. | Method and apparatus for creating an opening in the wall of a tubular vessel |
US6749621B2 (en) | 2002-02-21 | 2004-06-15 | Integrated Vascular Systems, Inc. | Sheath apparatus and methods for delivering a closure device |
EP1513453B1 (en) | 2002-06-04 | 2008-12-17 | Abbott Vascular Inc | Blood vessel closure clip and delivery device |
DE10259411A1 (en) * | 2002-12-19 | 2004-07-08 | Forschungszentrum Karlsruhe Gmbh | Medical clip and device for applying such a device |
US8398656B2 (en) | 2003-01-30 | 2013-03-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8905937B2 (en) | 2009-02-26 | 2014-12-09 | Integrated Vascular Systems, Inc. | Methods and apparatus for locating a surface of a body lumen |
US8202293B2 (en) | 2003-01-30 | 2012-06-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8900253B2 (en) | 2003-03-11 | 2014-12-02 | Covidien Lp | Clip applying apparatus with angled jaw |
US7267680B2 (en) | 2003-10-08 | 2007-09-11 | David Walter Wright | Anastomosis apparatus and methods of deployment and manufacture |
US20050203551A1 (en) * | 2004-03-09 | 2005-09-15 | Kevin Weadock | Method for performing a coronary artery bypass graft procedure |
US8425539B2 (en) | 2004-04-12 | 2013-04-23 | Xlumena, Inc. | Luminal structure anchoring devices and methods |
US7515970B2 (en) | 2004-08-18 | 2009-04-07 | Cardiac Pacemakers, Inc. | Transeptal lead |
CA2580931C (en) | 2004-09-23 | 2013-05-07 | Tyco Healthcare Group Lp | Clip applying apparatus and ligation clip |
US8409222B2 (en) | 2004-10-08 | 2013-04-02 | Covidien Lp | Endoscopic surgical clip applier |
ES2616731T3 (en) | 2004-10-08 | 2017-06-14 | Covidien Lp | Apparatus for applying surgical bras |
US7819886B2 (en) | 2004-10-08 | 2010-10-26 | Tyco Healthcare Group Lp | Endoscopic surgical clip applier |
US9763668B2 (en) | 2004-10-08 | 2017-09-19 | Covidien Lp | Endoscopic surgical clip applier |
AU2005294209B2 (en) | 2004-10-08 | 2011-04-07 | Covidien Lp | Endoscopic surgical clip applier |
JP5111112B2 (en) | 2004-12-08 | 2012-12-26 | エックスルミナ, インコーポレイテッド | Device for performing needle-guided therapy |
US20060201989A1 (en) * | 2005-03-11 | 2006-09-14 | Ojeda Herminio F | Surgical anvil and system for deploying the same |
AR054656A1 (en) * | 2005-04-03 | 2007-07-11 | Liliana Rosa Grinfeld | STENT FOR OSTIAL INJURIES AND VASCULAR FORKS |
US8784437B2 (en) | 2005-06-09 | 2014-07-22 | Xlumena, Inc. | Methods and devices for endosonography-guided fundoplexy |
US8777967B2 (en) | 2005-06-09 | 2014-07-15 | Xlumena, Inc. | Methods and devices for anchoring to tissue |
US8926633B2 (en) | 2005-06-24 | 2015-01-06 | Abbott Laboratories | Apparatus and method for delivering a closure element |
US8313497B2 (en) | 2005-07-01 | 2012-11-20 | Abbott Laboratories | Clip applier and methods of use |
US20070021759A1 (en) * | 2005-07-22 | 2007-01-25 | Ethicon Endo-Surgery, Inc. | Flexible endoscopic anastomotic ring applier device |
US8920442B2 (en) | 2005-08-24 | 2014-12-30 | Abbott Vascular Inc. | Vascular opening edge eversion methods and apparatuses |
US9456811B2 (en) | 2005-08-24 | 2016-10-04 | Abbott Vascular Inc. | Vascular closure methods and apparatuses |
USD629101S1 (en) | 2006-03-24 | 2010-12-14 | Tyco Healthcare Group Lp | Surgical clip applier |
USD625009S1 (en) | 2006-03-24 | 2010-10-05 | Tyco Healthcare Group Lp | Surgical clip applier |
US8556930B2 (en) | 2006-06-28 | 2013-10-15 | Abbott Laboratories | Vessel closure device |
EP2314232B1 (en) | 2006-10-17 | 2015-03-25 | Covidien LP | Apparatus for applying surgical clips |
AU2008230841B2 (en) | 2007-03-26 | 2013-09-12 | Covidien Lp | Endoscopic surgical clip applier |
EP2139401B1 (en) | 2007-04-11 | 2014-01-08 | Covidien LP | Surgical clip applier |
US8361092B1 (en) | 2007-06-18 | 2013-01-29 | Wilson T. Asfora | Vascular anastomosis device and method |
US9504469B2 (en) | 2007-06-18 | 2016-11-29 | Asfora Ip, Llc | Vascular anastomosis device and method |
US10004507B2 (en) | 2007-06-18 | 2018-06-26 | Asfora Ip, Llc | Vascular anastomosis device and method |
US8893947B2 (en) | 2007-12-17 | 2014-11-25 | Abbott Laboratories | Clip applier and methods of use |
US8454632B2 (en) | 2008-05-12 | 2013-06-04 | Xlumena, Inc. | Tissue anchor for securing tissue layers |
US9282965B2 (en) | 2008-05-16 | 2016-03-15 | Abbott Laboratories | Apparatus and methods for engaging tissue |
US8465502B2 (en) | 2008-08-25 | 2013-06-18 | Covidien Lp | Surgical clip applier and method of assembly |
US20110208212A1 (en) | 2010-02-19 | 2011-08-25 | Zergiebel Earl M | Surgical clip applier |
US8056565B2 (en) | 2008-08-25 | 2011-11-15 | Tyco Healthcare Group Lp | Surgical clip applier and method of assembly |
US8585717B2 (en) | 2008-08-29 | 2013-11-19 | Covidien Lp | Single stroke endoscopic surgical clip applier |
US8409223B2 (en) | 2008-08-29 | 2013-04-02 | Covidien Lp | Endoscopic surgical clip applier with clip retention |
US9358015B2 (en) | 2008-08-29 | 2016-06-07 | Covidien Lp | Endoscopic surgical clip applier with wedge plate |
US8267944B2 (en) | 2008-08-29 | 2012-09-18 | Tyco Healthcare Group Lp | Endoscopic surgical clip applier with lock out |
US8398676B2 (en) | 2008-10-30 | 2013-03-19 | Abbott Vascular Inc. | Closure device |
US8858594B2 (en) | 2008-12-22 | 2014-10-14 | Abbott Laboratories | Curved closure device |
US9414820B2 (en) | 2009-01-09 | 2016-08-16 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US20100179589A1 (en) | 2009-01-09 | 2010-07-15 | Abbott Vascular Inc. | Rapidly eroding anchor |
US9486191B2 (en) | 2009-01-09 | 2016-11-08 | Abbott Vascular, Inc. | Closure devices |
US9173644B2 (en) | 2009-01-09 | 2015-11-03 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US9089311B2 (en) | 2009-01-09 | 2015-07-28 | Abbott Vascular Inc. | Vessel closure devices and methods |
US20100185234A1 (en) | 2009-01-16 | 2010-07-22 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US9364259B2 (en) | 2009-04-21 | 2016-06-14 | Xlumena, Inc. | System and method for delivering expanding trocar through a sheath |
JP5535313B2 (en) | 2009-05-29 | 2014-07-02 | エックスルミナ, インコーポレイテッド | Device and method for deploying a stent across adjacent tissue layers |
US20110054492A1 (en) | 2009-08-26 | 2011-03-03 | Abbott Laboratories | Medical device for repairing a fistula |
US8734469B2 (en) | 2009-10-13 | 2014-05-27 | Covidien Lp | Suture clip applier |
US8348128B2 (en) * | 2009-11-11 | 2013-01-08 | Biorep Technologies, Inc. | Anastomosis system and method |
US9186136B2 (en) | 2009-12-09 | 2015-11-17 | Covidien Lp | Surgical clip applier |
US8545486B2 (en) | 2009-12-15 | 2013-10-01 | Covidien Lp | Surgical clip applier |
US8403945B2 (en) | 2010-02-25 | 2013-03-26 | Covidien Lp | Articulating endoscopic surgical clip applier |
US8968337B2 (en) | 2010-07-28 | 2015-03-03 | Covidien Lp | Articulating clip applier |
US8403946B2 (en) | 2010-07-28 | 2013-03-26 | Covidien Lp | Articulating clip applier cartridge |
CN103200907B (en) * | 2010-09-17 | 2015-11-25 | 托马斯·E·门泽尔 | For the internal gastric bander of obesity |
US9011464B2 (en) | 2010-11-02 | 2015-04-21 | Covidien Lp | Self-centering clip and jaw |
US9186153B2 (en) | 2011-01-31 | 2015-11-17 | Covidien Lp | Locking cam driver and jaw assembly for clip applier |
US9149276B2 (en) | 2011-03-21 | 2015-10-06 | Abbott Cardiovascular Systems, Inc. | Clip and deployment apparatus for tissue closure |
US9775623B2 (en) | 2011-04-29 | 2017-10-03 | Covidien Lp | Surgical clip applier including clip relief feature |
US20130131697A1 (en) | 2011-11-21 | 2013-05-23 | Covidien Lp | Surgical clip applier |
US9332976B2 (en) | 2011-11-30 | 2016-05-10 | Abbott Cardiovascular Systems, Inc. | Tissue closure device |
US9364239B2 (en) | 2011-12-19 | 2016-06-14 | Covidien Lp | Jaw closure mechanism for a surgical clip applier |
US9364216B2 (en) | 2011-12-29 | 2016-06-14 | Covidien Lp | Surgical clip applier with integrated clip counter |
US9408610B2 (en) | 2012-05-04 | 2016-08-09 | Covidien Lp | Surgical clip applier with dissector |
JP6360042B2 (en) | 2012-05-17 | 2018-07-18 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | Method and device for access across adjacent tissue layers |
US9532787B2 (en) | 2012-05-31 | 2017-01-03 | Covidien Lp | Endoscopic clip applier |
US9364209B2 (en) | 2012-12-21 | 2016-06-14 | Abbott Cardiovascular Systems, Inc. | Articulating suturing device |
US9113892B2 (en) | 2013-01-08 | 2015-08-25 | Covidien Lp | Surgical clip applier |
US9968362B2 (en) | 2013-01-08 | 2018-05-15 | Covidien Lp | Surgical clip applier |
US9750500B2 (en) | 2013-01-18 | 2017-09-05 | Covidien Lp | Surgical clip applier |
EP2958527B1 (en) | 2013-02-21 | 2020-07-22 | Boston Scientific Scimed, Inc. | Devices for forming an anastomosis |
WO2014158108A2 (en) * | 2013-03-26 | 2014-10-02 | Şahi̇n Mustafa | An anvil cap of a multiple umbrella type for circular staplers |
US9775624B2 (en) | 2013-08-27 | 2017-10-03 | Covidien Lp | Surgical clip applier |
US10702278B2 (en) | 2014-12-02 | 2020-07-07 | Covidien Lp | Laparoscopic surgical ligation clip applier |
US9931124B2 (en) | 2015-01-07 | 2018-04-03 | Covidien Lp | Reposable clip applier |
US10368876B2 (en) | 2015-01-15 | 2019-08-06 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10292712B2 (en) | 2015-01-28 | 2019-05-21 | Covidien Lp | Surgical clip applier with integrated cutter |
US10159491B2 (en) | 2015-03-10 | 2018-12-25 | Covidien Lp | Endoscopic reposable surgical clip applier |
WO2016165918A1 (en) | 2015-04-13 | 2016-10-20 | Innovative Interventional Technologies, B.V. | Anastomosis device for making anastomoses between hollow structures |
EP3284414A4 (en) * | 2015-04-17 | 2018-12-19 | Jichi Medical University | Anastomosis connector |
JP6626197B2 (en) | 2015-11-03 | 2019-12-25 | コヴィディエン リミテッド パートナーシップ | Endoscopic surgical clip applier |
US10390831B2 (en) | 2015-11-10 | 2019-08-27 | Covidien Lp | Endoscopic reposable surgical clip applier |
ES2880951T3 (en) | 2015-11-10 | 2021-11-26 | Covidien Lp | Endoscopic Surgical Staple Applicator with Limited Number of Uses |
WO2017079890A1 (en) | 2015-11-10 | 2017-05-18 | Covidien Lp | Endoscopic reposable surgical clip applier |
WO2017120734A1 (en) | 2016-01-11 | 2017-07-20 | Covidien Lp | Endoscopic reposable surgical clip applier |
JP6634521B2 (en) | 2016-01-18 | 2020-01-22 | コヴィディエン リミテッド パートナーシップ | Endoscopic surgical clip applier |
CA2958160A1 (en) | 2016-02-24 | 2017-08-24 | Covidien Lp | Endoscopic reposable surgical clip applier |
EP3496628A4 (en) | 2016-08-11 | 2020-04-22 | Covidien LP | Endoscopic surgical clip applier and clip applying systems |
AU2016420481A1 (en) | 2016-08-25 | 2019-01-17 | Covidien Lp | Endoscopic surgical clip applier and clip applying systems |
US10639044B2 (en) | 2016-10-31 | 2020-05-05 | Covidien Lp | Ligation clip module and clip applier |
US10660651B2 (en) | 2016-10-31 | 2020-05-26 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10426489B2 (en) | 2016-11-01 | 2019-10-01 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10492795B2 (en) | 2016-11-01 | 2019-12-03 | Covidien Lp | Endoscopic surgical clip applier |
US10610236B2 (en) | 2016-11-01 | 2020-04-07 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10709455B2 (en) | 2017-02-02 | 2020-07-14 | Covidien Lp | Endoscopic surgical clip applier |
US10758244B2 (en) | 2017-02-06 | 2020-09-01 | Covidien Lp | Endoscopic surgical clip applier |
AU2017397500A1 (en) | 2017-02-06 | 2019-07-11 | Covidien Lp | Surgical clip applier with user feedback feature |
US10660725B2 (en) | 2017-02-14 | 2020-05-26 | Covidien Lp | Endoscopic surgical clip applier including counter assembly |
US10603038B2 (en) | 2017-02-22 | 2020-03-31 | Covidien Lp | Surgical clip applier including inserts for jaw assembly |
US10548602B2 (en) | 2017-02-23 | 2020-02-04 | Covidien Lp | Endoscopic surgical clip applier |
US11583291B2 (en) | 2017-02-23 | 2023-02-21 | Covidien Lp | Endoscopic surgical clip applier |
US10675043B2 (en) | 2017-05-04 | 2020-06-09 | Covidien Lp | Reposable multi-fire surgical clip applier |
US10722235B2 (en) | 2017-05-11 | 2020-07-28 | Covidien Lp | Spring-release surgical clip |
US10639032B2 (en) | 2017-06-30 | 2020-05-05 | Covidien Lp | Endoscopic surgical clip applier including counter assembly |
US10660723B2 (en) | 2017-06-30 | 2020-05-26 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10675112B2 (en) | 2017-08-07 | 2020-06-09 | Covidien Lp | Endoscopic surgical clip applier including counter assembly |
US10932790B2 (en) | 2017-08-08 | 2021-03-02 | Covidien Lp | Geared actuation mechanism and surgical clip applier including the same |
US10863992B2 (en) | 2017-08-08 | 2020-12-15 | Covidien Lp | Endoscopic surgical clip applier |
US10786262B2 (en) | 2017-08-09 | 2020-09-29 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10786263B2 (en) | 2017-08-15 | 2020-09-29 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10835341B2 (en) | 2017-09-12 | 2020-11-17 | Covidien Lp | Endoscopic surgical clip applier and handle assemblies for use therewith |
US10758245B2 (en) | 2017-09-13 | 2020-09-01 | Covidien Lp | Clip counting mechanism for surgical clip applier |
US10653429B2 (en) | 2017-09-13 | 2020-05-19 | Covidien Lp | Endoscopic surgical clip applier |
US10835260B2 (en) | 2017-09-13 | 2020-11-17 | Covidien Lp | Endoscopic surgical clip applier and handle assemblies for use therewith |
US10932791B2 (en) | 2017-11-03 | 2021-03-02 | Covidien Lp | Reposable multi-fire surgical clip applier |
US11376015B2 (en) | 2017-11-03 | 2022-07-05 | Covidien Lp | Endoscopic surgical clip applier and handle assemblies for use therewith |
US10828036B2 (en) | 2017-11-03 | 2020-11-10 | Covidien Lp | Endoscopic surgical clip applier and handle assemblies for use therewith |
US10945734B2 (en) | 2017-11-03 | 2021-03-16 | Covidien Lp | Rotation knob assemblies and surgical instruments including the same |
US11116513B2 (en) | 2017-11-03 | 2021-09-14 | Covidien Lp | Modular surgical clip cartridge |
US10722236B2 (en) | 2017-12-12 | 2020-07-28 | Covidien Lp | Endoscopic reposable surgical clip applier |
US10849630B2 (en) | 2017-12-13 | 2020-12-01 | Covidien Lp | Reposable multi-fire surgical clip applier |
US10959737B2 (en) | 2017-12-13 | 2021-03-30 | Covidien Lp | Reposable multi-fire surgical clip applier |
US10743887B2 (en) | 2017-12-13 | 2020-08-18 | Covidien Lp | Reposable multi-fire surgical clip applier |
US11051827B2 (en) | 2018-01-16 | 2021-07-06 | Covidien Lp | Endoscopic surgical instrument and handle assemblies for use therewith |
US11134951B2 (en) | 2018-03-30 | 2021-10-05 | Cook Medicol Technologes, LLC | Side-to-side anastomosis system and punch tool for same |
CN112165910A (en) | 2018-04-17 | 2021-01-01 | D·吕贝克 | Apparatus and method for joining tubular structures |
US10993721B2 (en) | 2018-04-25 | 2021-05-04 | Covidien Lp | Surgical clip applier |
US10786273B2 (en) | 2018-07-13 | 2020-09-29 | Covidien Lp | Rotation knob assemblies for handle assemblies |
US11259887B2 (en) | 2018-08-10 | 2022-03-01 | Covidien Lp | Feedback mechanisms for handle assemblies |
US11344316B2 (en) | 2018-08-13 | 2022-05-31 | Covidien Lp | Elongated assemblies for surgical clip appliers and surgical clip appliers incorporating the same |
US11051828B2 (en) | 2018-08-13 | 2021-07-06 | Covidien Lp | Rotation knob assemblies and surgical instruments including same |
US11033256B2 (en) | 2018-08-13 | 2021-06-15 | Covidien Lp | Linkage assembly for reusable surgical handle assemblies |
US11246601B2 (en) | 2018-08-13 | 2022-02-15 | Covidien Lp | Elongated assemblies for surgical clip appliers and surgical clip appliers incorporating the same |
US11219463B2 (en) | 2018-08-13 | 2022-01-11 | Covidien Lp | Bilateral spring for surgical instruments and surgical instruments including the same |
US11278267B2 (en) | 2018-08-13 | 2022-03-22 | Covidien Lp | Latch assemblies and surgical instruments including the same |
US11253267B2 (en) | 2018-08-13 | 2022-02-22 | Covidien Lp | Friction reduction mechanisms for handle assemblies |
US11147566B2 (en) | 2018-10-01 | 2021-10-19 | Covidien Lp | Endoscopic surgical clip applier |
US11524398B2 (en) | 2019-03-19 | 2022-12-13 | Covidien Lp | Gear drive mechanisms for surgical instruments |
WO2020225603A1 (en) | 2019-05-07 | 2020-11-12 | Easyflomicro Inc. | Apparatuses for anastomosis of tubular vessels and related methods |
US11779340B2 (en) | 2020-01-02 | 2023-10-10 | Covidien Lp | Ligation clip loading device |
US11723669B2 (en) | 2020-01-08 | 2023-08-15 | Covidien Lp | Clip applier with clip cartridge interface |
Family Cites Families (184)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1251258A (en) | 1917-08-07 | 1917-12-25 | Harrison M Magill | Emergency wound-closer. |
US1756670A (en) | 1928-08-06 | 1930-04-29 | Lester A Treat | Vulva clamp |
US1918890A (en) | 1932-08-08 | 1933-07-18 | Joseph B Bacon | Surgical device |
US2434030A (en) | 1945-11-13 | 1948-01-06 | Yeomans Theron Grover | Sutureless method of rectosigmoid anastomosis and apparatus therefor |
US2453056A (en) | 1947-03-12 | 1948-11-02 | Zack William Edwin | Surgical anastomosis apparatus and method |
US2707783A (en) | 1950-09-20 | 1955-05-10 | Norman M Sullivan | Applicator for inserting preformed metallic sutures |
US3080564A (en) | 1959-09-10 | 1963-03-12 | Strekopitov Alexey Alexeevich | Instrument for stitching hollow organs |
US3040748A (en) | 1959-09-14 | 1962-06-26 | Ca Nat Research Council | Vascular positioning method and device |
GB935490A (en) | 1959-09-15 | 1963-08-28 | Res Inst Of Ex Surgical Appara | An instrument for suturing blood vessels and nerves |
FR1315234A (en) | 1961-12-09 | 1963-01-18 | Force transmission device in a flexible sheath | |
US3254650A (en) | 1962-03-19 | 1966-06-07 | Michael B Collito | Surgical anastomosis methods and devices |
CA736256A (en) | 1962-08-27 | 1966-06-14 | S. Kasoolin Viacheslav | Instrument for suturing esophagus to intestine or stomach |
US3254651A (en) | 1962-09-12 | 1966-06-07 | Babies Hospital | Surgical anastomosis methods and devices |
US3252643A (en) | 1962-12-24 | 1966-05-24 | Strekopytov Alexey Alexcevich | Instrument for suturing living tissue |
US3269630A (en) | 1964-04-30 | 1966-08-30 | Fleischer Harry | Stapling instrument |
FR1461464A (en) | 1965-08-20 | 1966-02-25 | Niiex Khirurgicheskoi Apparatu | Surgical device for suturing organs |
US3494533A (en) | 1966-10-10 | 1970-02-10 | United States Surgical Corp | Surgical stapler for stitching body organs |
US3519187A (en) | 1966-12-06 | 1970-07-07 | Nickolai Nickolajevich Kapitan | Instrument for suturing vessels |
FR1518083A (en) | 1967-03-03 | 1968-03-22 | Pfau Wanfried G M B H H | Device for anastomosis of blood vessels |
DE1791114B1 (en) | 1967-09-19 | 1971-12-02 | Vnii Chirurgitscheskoj Apparat | Surgical device for stapling tissues |
US3452615A (en) | 1967-10-12 | 1969-07-01 | Controlex Corp America | Tubular flexible remote control device |
CA851958A (en) * | 1968-01-31 | 1970-09-22 | J. Van Der Hoeven Cornelis | Reflector device |
CH470170A (en) | 1968-02-02 | 1969-03-31 | Vnii Khirurgicheskoi Apparatur | Device for applying round anastomoses |
US3593903A (en) | 1968-07-12 | 1971-07-20 | Vnii Khirurgicheskoi Apparatur | Surgical instrument for suturing hollow organs in infants |
US3570497A (en) | 1969-01-16 | 1971-03-16 | Gerald M Lemole | Suture apparatus and methods |
US3657744A (en) | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US3638652A (en) | 1970-06-01 | 1972-02-01 | James L Kelley | Surgical instrument for intraluminal anastomosis |
BE758685A (en) | 1970-10-14 | 1971-05-10 | Vnii Khirurgicheskoi Apparatur | SURGICAL APPARATUS FOR TISSUE SUTURE WITH STAPLES |
US3774615A (en) | 1971-02-08 | 1973-11-27 | Ceskoslovenska Akademie Ved | Device for connecting or joining the ends of interrupted tubular organs in surgical operations without stitching |
US3805793A (en) | 1973-03-21 | 1974-04-23 | S Wright | Anastomotic apparatus |
CH557672A (en) | 1973-07-04 | 1975-01-15 | Vnii Khirurgicheskoi Apparatur | SURGICAL DEVICE WITH MEANS FOR REPLACING VOLLUS ORGANS. |
US4018228A (en) * | 1975-02-24 | 1977-04-19 | Goosen Carl C | Surgical punch apparatus |
SU571253A1 (en) | 1975-07-11 | 1977-09-05 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Apparatus fir suturing vessels with metal clips |
US4166466A (en) | 1976-10-08 | 1979-09-04 | Jarvik Robert K | Repeating hemostatic clip applying instruments and multi-clip cartridges therefor |
DE2657255A1 (en) | 1976-12-17 | 1978-06-29 | P H Dr Schomacher | DEVICE FOR CLOSING SEPARATED BODY BARRELS |
US4140126A (en) | 1977-02-18 | 1979-02-20 | Choudhury M Hasan | Method for performing aneurysm repair |
US4573468A (en) | 1977-05-26 | 1986-03-04 | United States Surgical Corporation | Hollow body organ stapling instrument and disposable cartridge employing relief vents |
US4603693A (en) | 1977-05-26 | 1986-08-05 | United States Surgical Corporation | Instrument for circular surgical stapling of hollow body organs and disposable cartridge therefor |
US4304236A (en) | 1977-05-26 | 1981-12-08 | United States Surgical Corporation | Stapling instrument having an anvil-carrying part of particular geometric shape |
CA1082552A (en) | 1977-08-05 | 1980-07-29 | Charles H. Klieman | Hemostatic clip applicator |
NL7711347A (en) | 1977-10-17 | 1979-04-19 | Carl Robert Erik Daantje | Stapling instrument for joining intestine ends - has head coupling rod in two parts screwing together with hand grip |
DE2822603A1 (en) | 1978-05-24 | 1979-11-29 | Kay Dr Thierfelder | Tissue fault closing instrument - has skin fixed to scissor type supports expanded radially catheter in probe |
DE2947107A1 (en) | 1978-12-07 | 1980-06-26 | United States Surgical Corp | ACCURATELY ALIGNED CARTRIDGE AND INSTRUMENT FOR CLAMPING ANASTOMOSES |
US4214587A (en) | 1979-02-12 | 1980-07-29 | Sakura Chester Y Jr | Anastomosis device and method |
SU1088712A1 (en) | 1979-11-14 | 1984-04-30 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Apparatus for circular suture of blood vessels |
US4352358A (en) | 1979-12-28 | 1982-10-05 | Angelchik Jean P | Apparatus for effecting anastomotic procedures |
US4466436A (en) | 1980-01-17 | 1984-08-21 | Sukoo Lee | Surgical stapler |
US4319576A (en) | 1980-02-26 | 1982-03-16 | Senco Products, Inc. | Intralumenal anastomosis surgical stapling instrument |
US4368736A (en) | 1980-11-17 | 1983-01-18 | Kaster Robert L | Anastomotic fitting |
US4366819A (en) | 1980-11-17 | 1983-01-04 | Kaster Robert L | Anastomotic fitting |
SU995765A1 (en) | 1981-07-01 | 1983-02-15 | Московский Городской Ордена Ленина И Ордена Трудового Красного Знамени Научно-Исследовательский Институт Скорой Помощи Им.Н.В.Склифосовского | Apparatus for applying anastomosis onto hollow organs |
US4576167A (en) | 1981-09-03 | 1986-03-18 | United States Surgical Corporation | Surgical stapler apparatus with curved shaft |
GB2108418A (en) | 1981-10-23 | 1983-05-18 | Vnii Ispytatel Med Tech | Device for applying anastomoses onto hollow organs |
SU1097301A1 (en) | 1982-01-04 | 1984-06-15 | Петрозаводский государственный университет им.О.В.Куусинена | Surgical suture appliance for placing anastomosis of hollow organs |
US4474181A (en) | 1982-02-18 | 1984-10-02 | Schenck Robert R | Method and apparatus for anastomosing small blood vessels |
US4624255A (en) | 1982-02-18 | 1986-11-25 | Schenck Robert R | Apparatus for anastomosing living vessels |
SU1114405A1 (en) * | 1982-02-23 | 1984-09-23 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Surgical suturing apparatus for placing compression anastomoses on the organs of digestive tract |
SE431609B (en) | 1982-06-24 | 1984-02-20 | Unilink Ab | SURGICAL INSTRUMENT FOR THE ASTAD COMMAND OF ANASTOMOS AND ITS PARTS |
US4917091A (en) | 1982-06-24 | 1990-04-17 | Unilink Ab | Annular fastening means |
US5177112A (en) | 1983-01-03 | 1993-01-05 | Whitby Research, Inc. | Substituted 2-aminotetralins |
US5256661A (en) | 1983-01-03 | 1993-10-26 | Whitby Research, Inc. | Substituted 2-aminotetralins and pharmaceutical use |
US4512338A (en) | 1983-01-25 | 1985-04-23 | Balko Alexander B | Process for restoring patency to body vessels |
US4523592A (en) | 1983-04-25 | 1985-06-18 | Rollin K. Daniel P.S.C. | Anastomotic coupling means capable of end-to-end and end-to-side anastomosis |
US4607637A (en) | 1983-07-22 | 1986-08-26 | Anders Berggren | Surgical instrument for performing anastomosis with the aid of ring-like fastening elements and the fastening elements for performing anastomosis |
US4592354A (en) | 1983-10-11 | 1986-06-03 | Senmed, Inc. | Tissue retention spool for intraluminal anastomotic surgical stapling instrument and methods |
US4505414A (en) | 1983-10-12 | 1985-03-19 | Filipi Charles J | Expandable anvil surgical stapler |
US4665906A (en) | 1983-10-14 | 1987-05-19 | Raychem Corporation | Medical devices incorporating sim alloy elements |
US4586503A (en) | 1983-12-01 | 1986-05-06 | University Of New Mexico | Surgical microclip |
US5104399A (en) | 1986-12-10 | 1992-04-14 | Endovascular Technologies, Inc. | Artificial graft and implantation method |
US5669936A (en) | 1983-12-09 | 1997-09-23 | Endovascular Technologies, Inc. | Endovascular grafting system and method for use therewith |
US4917087A (en) | 1984-04-10 | 1990-04-17 | Walsh Manufacturing (Mississuaga) Limited | Anastomosis devices, kits and method |
US4657019A (en) | 1984-04-10 | 1987-04-14 | Idea Research Investment Fund, Inc. | Anastomosis devices and kits |
US4573488A (en) * | 1984-04-12 | 1986-03-04 | The Dow Chemical Company | Additives for nonaqueous liquids |
US4703887A (en) | 1985-01-28 | 1987-11-03 | Ethicon, Inc. | Collapsible purse string aid for use with intraluminal stapling device |
US4593693A (en) | 1985-04-26 | 1986-06-10 | Schenck Robert R | Methods and apparatus for anastomosing living vessels |
CN85106639B (en) | 1985-09-03 | 1988-08-03 | 第三军医大学野战外科研究所 | Instrument for blood vessel anastomosis |
US5102417A (en) | 1985-11-07 | 1992-04-07 | Expandable Grafts Partnership | Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft |
US4681110A (en) | 1985-12-02 | 1987-07-21 | Wiktor Dominik M | Catheter arrangement having a blood vessel liner, and method of using it |
US4700703A (en) | 1986-03-27 | 1987-10-20 | Semion Resnick | Cartridge assembly for a surgical stapling instrument |
US4800882A (en) | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
US5119983A (en) | 1987-05-26 | 1992-06-09 | United States Surgical Corporation | Surgical stapler apparatus |
US4872874A (en) | 1987-05-29 | 1989-10-10 | Taheri Syde A | Method and apparatus for transarterial aortic graft insertion and implantation |
SU1616624A1 (en) | 1987-07-14 | 1990-12-30 | Предприятие П/Я А-3697 | Surgical suturing apparatus |
US4907591A (en) | 1988-03-29 | 1990-03-13 | Pfizer Hospital Products Group, Inc. | Surgical instrument for establishing compression anastomosis |
US5336233A (en) | 1989-01-26 | 1994-08-09 | Chen Fusen H | Anastomotic device |
US4930674A (en) | 1989-02-24 | 1990-06-05 | Abiomed, Inc. | Surgical stapler |
ES2011131A6 (en) | 1989-04-18 | 1989-12-16 | Kanshin Nikolai Nikolaevich | Stem for surgical suture apparatus. |
US5053047A (en) | 1989-05-16 | 1991-10-01 | Inbae Yoon | Suture devices particularly useful in endoscopic surgery and methods of suturing |
US5324447A (en) | 1989-10-02 | 1994-06-28 | Allergan, Inc. | Method and activator compositions to disinfect lenses |
EP0441516B1 (en) | 1990-02-08 | 1995-03-29 | Howmedica Inc. | Inflatable stent |
FR2663217B1 (en) * | 1990-06-15 | 1992-10-16 | Antheor | FILTERING DEVICE FOR THE PREVENTION OF EMBOLIES. |
US5035702A (en) | 1990-06-18 | 1991-07-30 | Taheri Syde A | Method and apparatus for providing an anastomosis |
US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5234447A (en) | 1990-08-28 | 1993-08-10 | Robert L. Kaster | Side-to-end vascular anastomotic staple apparatus |
US5403333A (en) | 1990-08-28 | 1995-04-04 | Robert L. Kaster | Side-to-end vascular anastomotic staple apparatus |
US5250058A (en) | 1991-01-17 | 1993-10-05 | Ethicon, Inc. | Absorbable anastomosic fastener means |
CA2202800A1 (en) | 1991-04-11 | 1992-10-12 | Alec A. Piplani | Endovascular graft having bifurcation and apparatus and method for deploying the same |
GB9111972D0 (en) | 1991-06-04 | 1991-07-24 | Clinical Product Dev Ltd | Medical/surgical devices |
US5304220A (en) | 1991-07-03 | 1994-04-19 | Maginot Thomas J | Method and apparatus for implanting a graft prosthesis in the body of a patient |
EP0593600B1 (en) | 1991-07-04 | 1999-01-13 | OWEN, Earl Ronald | Tubular surgical implant |
GR920100358A (en) | 1991-08-23 | 1993-06-07 | Ethicon Inc | Surgical anastomosis stapling instrument. |
US5333773A (en) | 1991-08-23 | 1994-08-02 | Ethicon, Inc. | Sealing means for endoscopic surgical anastomosis stapling instrument |
US5387235A (en) | 1991-10-25 | 1995-02-07 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm |
EP0539237A1 (en) | 1991-10-25 | 1993-04-28 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm and method for implanting |
US5720776A (en) * | 1991-10-25 | 1998-02-24 | Cook Incorporated | Barb and expandable transluminal graft prosthesis for repair of aneurysm |
US5197649A (en) | 1991-10-29 | 1993-03-30 | The Trustees Of Columbia University In The City Of New York | Gastrointestinal endoscoptic stapler |
US5258042A (en) | 1991-12-16 | 1993-11-02 | Henry Ford Health System | Intravascular hydrogel implant |
US5292063A (en) * | 1992-02-04 | 1994-03-08 | Johnson Service Company | Damper actuator |
US5188638A (en) | 1992-02-06 | 1993-02-23 | Tzakis Andreas G | Apparatus and method for preforming anastomosis fastener securement of hollow organs |
US5271543A (en) | 1992-02-07 | 1993-12-21 | Ethicon, Inc. | Surgical anastomosis stapling instrument with flexible support shaft and anvil adjusting mechanism |
US5348259A (en) | 1992-02-10 | 1994-09-20 | Massachusetts Institute Of Technology | Flexible, articulable column |
US5242457A (en) | 1992-05-08 | 1993-09-07 | Ethicon, Inc. | Surgical instrument and staples for applying purse string sutures |
JPH0647050A (en) | 1992-06-04 | 1994-02-22 | Olympus Optical Co Ltd | Tissue suture and ligature device |
US5366473A (en) | 1992-08-18 | 1994-11-22 | Ultrasonic Sensing And Monitoring Systems, Inc. | Method and apparatus for applying vascular grafts |
US5522834A (en) * | 1992-10-15 | 1996-06-04 | Applied Medical Resources Corporation | Internal mammary artery catheter and method |
US5478354A (en) | 1993-07-14 | 1995-12-26 | United States Surgical Corporation | Wound closing apparatus and method |
US5395000A (en) * | 1993-07-19 | 1995-03-07 | Porter; Billy J. | Liquid container with reseatable stopper |
CA2125258C (en) | 1993-08-05 | 1998-12-22 | Dinah B Quiachon | Multicapsule intraluminal grafting system and method |
US5562690A (en) | 1993-11-12 | 1996-10-08 | United States Surgical Corporation | Apparatus and method for performing compressional anastomoses |
US5683451A (en) * | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
CA2192819A1 (en) * | 1994-06-17 | 1995-12-28 | Christopher Francis Heck | Surgical stapling instrument and method thereof |
US5732872A (en) * | 1994-06-17 | 1998-03-31 | Heartport, Inc. | Surgical stapling instrument |
US5881943A (en) * | 1994-06-17 | 1999-03-16 | Heartport, Inc. | Surgical anastomosis apparatus and method thereof |
US5522881A (en) | 1994-06-28 | 1996-06-04 | Meadox Medicals, Inc. | Implantable tubular prosthesis having integral cuffs |
US5397355A (en) | 1994-07-19 | 1995-03-14 | Stentco, Inc. | Intraluminal stent |
US5807243A (en) | 1994-08-31 | 1998-09-15 | Heartport, Inc. | Method for isolating a surgical site |
US5843170A (en) | 1994-09-02 | 1998-12-01 | Ahn; Sam Seunghae | Apparatus and method for performing aneurysm repair |
NL9401633A (en) * | 1994-10-04 | 1996-05-01 | Surgical Innovations Vof | Assembly for the treatment of blood vessels and a method thereof. |
AU3783195A (en) | 1994-11-15 | 1996-05-23 | Advanced Cardiovascular Systems Inc. | Intraluminal stent for attaching a graft |
US5554162A (en) | 1994-12-02 | 1996-09-10 | Delange; Gregory S. | Method and device for surgically joining luminal structures |
US5868760A (en) * | 1994-12-07 | 1999-02-09 | Mcguckin, Jr.; James F. | Method and apparatus for endolumenally resectioning tissue |
US5620452A (en) * | 1994-12-22 | 1997-04-15 | Yoon; Inbae | Surgical clip with ductile tissue penetrating members |
US5591226A (en) * | 1995-01-23 | 1997-01-07 | Schneider (Usa) Inc. | Percutaneous stent-graft and method for delivery thereof |
US5634936A (en) | 1995-02-06 | 1997-06-03 | Scimed Life Systems, Inc. | Device for closing a septal defect |
US6110187A (en) | 1995-02-24 | 2000-08-29 | Heartport, Inc. | Device and method for minimizing heart displacements during a beating heart surgical procedure |
US5797933A (en) | 1996-07-16 | 1998-08-25 | Heartport, Inc. | Coronary shunt and method of use |
US5695504A (en) * | 1995-02-24 | 1997-12-09 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5839639A (en) | 1995-08-17 | 1998-11-24 | Lasersurge, Inc. | Collapsible anvil assembly and applicator instrument |
US5836311A (en) * | 1995-09-20 | 1998-11-17 | Medtronic, Inc. | Method and apparatus for temporarily immobilizing a local area of tissue |
JPH11514269A (en) * | 1995-10-13 | 1999-12-07 | トランスバスキュラー インコーポレイテッド | Methods and apparatus for bypassing arterial occlusion and / or performing other transvascular approaches |
DE19542733A1 (en) | 1995-11-16 | 1997-07-24 | Mathias Mandlier | System for anastomising blood vessels |
EP0932426A4 (en) | 1996-02-02 | 2003-07-30 | Transvascular Inc | Methods and apparatus for connecting openings formed in adjacent blood vessels or other anatomical structures |
US5727569A (en) * | 1996-02-20 | 1998-03-17 | Cardiothoracic Systems, Inc. | Surgical devices for imposing a negative pressure to fix the position of cardiac tissue during surgery |
EP0904001A1 (en) * | 1996-04-26 | 1999-03-31 | Genzyme Corporation | Coronary stabilizing retractor |
KR100298040B1 (en) * | 1996-04-30 | 2001-10-29 | 닐스 자코브슨 | Methods and anastomosis apparatus for use when performing end-to-side anastomosis |
IT1284075B1 (en) * | 1996-06-26 | 1998-05-08 | Blend S R L | EQUIPMENT FOR THE PRODUCTION AND CONTEMPORARY DISTRIBUTION OF CEMENTITIOUS AND SIMILAR DOUGH |
US5707380A (en) | 1996-07-23 | 1998-01-13 | United States Surgical Corporation | Anastomosis instrument and method |
US5833698A (en) | 1996-07-23 | 1998-11-10 | United States Surgical Corporation | Anastomosis instrument and method |
US6024748A (en) | 1996-07-23 | 2000-02-15 | United States Surgical Corporation | Singleshot anastomosis instrument with detachable loading unit and method |
US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
US6565581B1 (en) * | 1996-09-16 | 2003-05-20 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US5976178A (en) | 1996-11-07 | 1999-11-02 | Vascular Science Inc. | Medical grafting methods |
US6036702A (en) * | 1997-04-23 | 2000-03-14 | Vascular Science Inc. | Medical grafting connectors and fasteners |
US5893369A (en) * | 1997-02-24 | 1999-04-13 | Lemole; Gerald M. | Procedure for bypassing an occlusion in a blood vessel |
US6035856A (en) * | 1997-03-06 | 2000-03-14 | Scimed Life Systems | Percutaneous bypass with branching vessel |
US6056762A (en) * | 1997-05-22 | 2000-05-02 | Kensey Nash Corporation | Anastomosis system and method of use |
US6019722A (en) * | 1997-09-17 | 2000-02-01 | Guidant Corporation | Device to permit offpump beating heart coronary bypass surgery |
AU9509498A (en) | 1997-09-26 | 1999-04-12 | Corvascular Surgical Systems, Inc. | Perfusion-occlusion catheter and methods |
US6074416A (en) * | 1997-10-09 | 2000-06-13 | St. Jude Medical Cardiovascular Group, Inc. | Wire connector structures for tubular grafts |
NL1007349C2 (en) * | 1997-10-24 | 1999-04-27 | Suyker Wilhelmus Joseph Leonardus | System for the mechanical production of anastomoses between hollow structures; as well as device and applicator for use therewith. |
US5976176A (en) | 1997-10-31 | 1999-11-02 | Webb, Ii; Matt M | Body heating device |
US6193734B1 (en) * | 1998-01-23 | 2001-02-27 | Heartport, Inc. | System for performing vascular anastomoses |
EP1051128B1 (en) * | 1998-01-30 | 2006-03-15 | St. Jude Medical ATG, Inc. | Medical graft connector or plug structures, and methods of making |
US5951576A (en) * | 1998-03-02 | 1999-09-14 | Wakabayashi; Akio | End-to-side vascular anastomosing stapling device |
US6051007A (en) * | 1998-03-02 | 2000-04-18 | Corvascular, Inc. | Sternal closure device and instruments therefor |
US6095997A (en) | 1998-03-04 | 2000-08-01 | Corvascular, Inc. | Intraluminal shunt and methods of use |
US6110188A (en) | 1998-03-09 | 2000-08-29 | Corvascular, Inc. | Anastomosis method |
US6176864B1 (en) * | 1998-03-09 | 2001-01-23 | Corvascular, Inc. | Anastomosis device and method |
US6241741B1 (en) * | 1998-03-09 | 2001-06-05 | Corvascular Surgical Systems, Inc. | Anastomosis device and method |
US6113588A (en) | 1998-03-13 | 2000-09-05 | Corvascular, Inc. | Transillumination catheter and method |
US6080175A (en) * | 1998-07-29 | 2000-06-27 | Corvascular, Inc. | Surgical cutting instrument and method of use |
US6063021A (en) * | 1998-07-31 | 2000-05-16 | Pilling Weck Incorporated | Stabilizer for surgery |
US6152937A (en) | 1998-11-06 | 2000-11-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical graft connector and methods of making and installing same |
US6113612A (en) * | 1998-11-06 | 2000-09-05 | St. Jude Medical Cardiovascular Group, Inc. | Medical anastomosis apparatus |
AU3729400A (en) * | 1999-03-09 | 2000-09-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical grafting methods and apparatus |
US6569173B1 (en) * | 1999-12-14 | 2003-05-27 | Integrated Vascular Interventional Technologies, L.C. | Compression plate anastomosis apparatus |
US6551334B2 (en) * | 1999-04-16 | 2003-04-22 | Integrated Vascular Interventional Technologies, Lc | Externally directed anastomosis systems and externally positioned anastomosis fenestra cutting apparatus |
AU5317500A (en) * | 1999-06-04 | 2000-12-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical grafting apparatus and methods |
USD440304S1 (en) * | 1999-10-27 | 2001-04-10 | Corvascular, Inc. | Direct fluid-delivery system |
US6602263B1 (en) * | 1999-11-30 | 2003-08-05 | St. Jude Medical Atg, Inc. | Medical grafting methods and apparatus |
WO2002019924A1 (en) * | 2000-09-01 | 2002-03-14 | Angiolink Corporation | Wound site management and wound closure device |
US6966917B1 (en) * | 2000-11-09 | 2005-11-22 | Innovation Interventional Technologies B.V. | Deformable connector for mechanically connecting hollow structures |
US6769590B2 (en) * | 2001-04-02 | 2004-08-03 | Susan E. Vresh | Luminal anastomotic device and method |
-
2000
- 2000-11-09 US US09/708,617 patent/US6966917B1/en not_active Expired - Lifetime
-
2001
- 2001-11-09 AT AT06112731T patent/ATE405215T1/en active
- 2001-11-09 EP EP06112731A patent/EP1683491B1/en not_active Expired - Lifetime
- 2001-11-09 CA CA2436835A patent/CA2436835C/en not_active Expired - Fee Related
- 2001-11-09 AU AU2421402A patent/AU2421402A/en active Pending
- 2001-11-09 EP EP01993428A patent/EP1341448B1/en not_active Expired - Lifetime
- 2001-11-09 AT AT01993428T patent/ATE323447T1/en not_active IP Right Cessation
- 2001-11-09 JP JP2002540645A patent/JP4167060B2/en not_active Expired - Fee Related
- 2001-11-09 IL IL15576401A patent/IL155764A0/en unknown
- 2001-11-09 US US10/416,433 patent/US8066723B2/en not_active Expired - Fee Related
- 2001-11-09 AU AU2002224214A patent/AU2002224214B2/en not_active Ceased
- 2001-11-09 ES ES01993428T patent/ES2261514T3/en not_active Expired - Lifetime
- 2001-11-09 DE DE60135510T patent/DE60135510D1/en not_active Expired - Lifetime
- 2001-11-09 ES ES06112731T patent/ES2313553T3/en not_active Expired - Lifetime
- 2001-11-09 WO PCT/NL2001/000815 patent/WO2002038055A2/en active IP Right Grant
- 2001-11-09 EP EP08162624A patent/EP1987783A3/en not_active Withdrawn
- 2001-11-09 DK DK06112731T patent/DK1683491T3/en active
- 2001-11-09 PT PT06112731T patent/PT1683491E/en unknown
- 2001-11-09 DE DE60118959T patent/DE60118959T2/en not_active Expired - Lifetime
-
2005
- 2005-08-12 US US11/202,804 patent/US20050288693A1/en not_active Abandoned
-
2008
- 2008-04-16 JP JP2008107307A patent/JP4870714B2/en not_active Expired - Fee Related
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