AU2002223868A1 - Granulation process - Google Patents

Granulation process

Info

Publication number
AU2002223868A1
AU2002223868A1 AU2002223868A AU2386802A AU2002223868A1 AU 2002223868 A1 AU2002223868 A1 AU 2002223868A1 AU 2002223868 A AU2002223868 A AU 2002223868A AU 2386802 A AU2386802 A AU 2386802A AU 2002223868 A1 AU2002223868 A1 AU 2002223868A1
Authority
AU
Australia
Prior art keywords
halogenated hydrocarbon
granulation process
tetraflouroethane
cycled
granulated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002223868A
Inventor
Christopher Edmund Valder
John Peter Warr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU2002223868A1 publication Critical patent/AU2002223868A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A wet granulation process in which a pharmaceutical substance is granulated using a granulating fluid which is a halogenated hydrocarbon which has a normal boiling point below ambient temperature, for example 1,1,1,2-tetraflouroethane, under a pressure sufficient to maintain the halogenated hydrocarbon in a liquid state. A process in which the halogenated hydrocarbon is re-cycled, and suitable equipment for performing the process is also described.
AU2002223868A 2000-11-24 2001-11-22 Granulation process Abandoned AU2002223868A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0028709.4 2000-11-24
GBGB0028709.4A GB0028709D0 (en) 2000-11-24 2000-11-24 Process
PCT/GB2001/005153 WO2002041874A2 (en) 2000-11-24 2001-11-22 Granulation process

Publications (1)

Publication Number Publication Date
AU2002223868A1 true AU2002223868A1 (en) 2002-06-03

Family

ID=9903830

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002223868A Abandoned AU2002223868A1 (en) 2000-11-24 2001-11-22 Granulation process

Country Status (9)

Country Link
US (1) US7214389B2 (en)
EP (1) EP1341525B1 (en)
JP (1) JP2004520280A (en)
AT (1) ATE371440T1 (en)
AU (1) AU2002223868A1 (en)
DE (1) DE60130248T2 (en)
ES (1) ES2290198T3 (en)
GB (1) GB0028709D0 (en)
WO (1) WO2002041874A2 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2246013A1 (en) * 1972-09-20 1974-03-28 Boehringer Mannheim Gmbh PROCESS FOR THE MANUFACTURING OF POROUS TABLETS
DE2556561C2 (en) * 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Process for the production of porous tablets
JPS60152407A (en) * 1984-01-19 1985-08-10 Shiseido Co Ltd External preparation for skin blended with granule
CH671402A5 (en) * 1985-10-02 1989-08-31 Sandoz Ag
GB8624628D0 (en) * 1986-10-14 1986-11-19 Scras Soluble/splitable tablets
JPH07265682A (en) 1988-02-17 1995-10-17 Showa Shell Sekiyu Kk Production of organic material fine particle
DE4012416A1 (en) * 1990-04-19 1991-10-24 Dynamit Nobel Ag Producing granulating powdered water-soluble substances - by dispersing in a soln. of granulating agent, pref. polysulphone, in organic solvent, then agglomerating by addn. of a non-solvent
US5403593A (en) * 1991-03-04 1995-04-04 Sandoz Ltd. Melt granulated compositions for preparing sustained release dosage forms

Also Published As

Publication number Publication date
JP2004520280A (en) 2004-07-08
DE60130248D1 (en) 2007-10-11
WO2002041874A3 (en) 2002-08-22
EP1341525A2 (en) 2003-09-10
WO2002041874A2 (en) 2002-05-30
EP1341525B1 (en) 2007-08-29
US7214389B2 (en) 2007-05-08
ATE371440T1 (en) 2007-09-15
DE60130248T2 (en) 2008-06-19
GB0028709D0 (en) 2001-01-10
ES2290198T3 (en) 2008-02-16
US20040070102A1 (en) 2004-04-15

Similar Documents

Publication Publication Date Title
IS6348A (en) (1a, 3a, 5a) (3-Aminomethyl bicyclo [3.2.0] hept-3-yl) -acetic acid, pharmaceutical formulations and use of the compound for the manufacture of pharmaceuticals
WO2004000389A3 (en) Rapidly dissolving micro-perforator for drug delivery and other applications
EP0314340A3 (en) Liquid transfer device
WO2001017453A3 (en) Systems and methods for monitoring and controlling use of medical devices
CA2311200A1 (en) Carbon dioxide recovery from an oxygen containing mixture
WO2002030506A3 (en) Transdermal method
BR0100130A (en) Cryogenic liquid supply system, apparatus mounted inside a reaction vessel, and cryogenic liquid supply apparatus
WO2005035142A3 (en) Liquid product applicator
NZ526942A (en) A process for preparing particles of a substance using an anti-solvent technique
AU5523599A (en) Method for preparing novel fenofibrate galenic formulations, galenic formulations obtained and applications
AU6453600A (en) Monitoring instrument
AU7922800A (en) Deblocking contact lenses
AU2002223868A1 (en) Granulation process
PT90991A (en) PROCESS FOR THE PREPARATION OF PESTICIDES IN PILLS
AU2003289863A1 (en) Pressure-injection hand-held device for introducing substances, which are under the pressure of a gaseous or liquid pressure medium, into a skin location to be treated
AU5383599A (en) Inflation device
FR2706202B1 (en) Device for the simultaneous ejection of two fluids, in particular pyrotechnics.
WO2003088314A3 (en) Remote monitoring system for chemical liquid delivery
WO1999026680A3 (en) A container for a hypodermic syringe
WO2002022171A3 (en) Pharmaceutical composition having specific water activity
WO2002046922A3 (en) A software configuration system and the creation and use thereof
ITRM930603A1 (en) PROCEDURE FOR POLYMERIZING HIGH TEMPERATURE AND HIGH PRESSURE ETHYLENE.
UA40595C2 (en) Process for the preparation of an iridium-containing solution and the solution obtained
JPS53115906A (en) Verylow temperature fluid pump
Galligan et al. Integrating tool control into a standard manufacturing system