AU2002221713A1 - Modified phage, comprising a non-lytic modification and expressing a kil-gene - Google Patents

Modified phage, comprising a non-lytic modification and expressing a kil-gene

Info

Publication number
AU2002221713A1
AU2002221713A1 AU2002221713A AU2171302A AU2002221713A1 AU 2002221713 A1 AU2002221713 A1 AU 2002221713A1 AU 2002221713 A AU2002221713 A AU 2002221713A AU 2171302 A AU2171302 A AU 2171302A AU 2002221713 A1 AU2002221713 A1 AU 2002221713A1
Authority
AU
Australia
Prior art keywords
kil
lytic
expressing
gene
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002221713A
Inventor
Udo Blasi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valneva Austria GmbH
Original Assignee
CISTEM Biotechnologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CISTEM Biotechnologies GmbH filed Critical CISTEM Biotechnologies GmbH
Publication of AU2002221713A1 publication Critical patent/AU2002221713A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/00061Methods of inactivation or attenuation
    • C12N2770/00062Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2002221713A 2000-10-25 2001-10-22 Modified phage, comprising a non-lytic modification and expressing a kil-gene Abandoned AU2002221713A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT1826/2000 2000-10-25
AT18262000 2000-10-25
PCT/EP2001/012169 WO2002034892A1 (en) 2000-10-25 2001-10-22 Modified phage, comprising a non-lytic modification and expressing a kil-gene

Publications (1)

Publication Number Publication Date
AU2002221713A1 true AU2002221713A1 (en) 2002-05-06

Family

ID=3689059

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002221713A Abandoned AU2002221713A1 (en) 2000-10-25 2001-10-22 Modified phage, comprising a non-lytic modification and expressing a kil-gene

Country Status (2)

Country Link
AU (1) AU2002221713A1 (en)
WO (1) WO2002034892A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003026767A2 (en) * 2001-09-27 2003-04-03 Gangagen, Inc. Lysin-deficient bacteriophages having reduced immunogenicity
WO2004046319A2 (en) * 2002-11-14 2004-06-03 Gangagen, Inc. Bacteriophage having modified holin and uses thereof
DE102007003148A1 (en) * 2007-01-15 2008-07-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Genetically modified bacteriophages, in particular for controlling pathogenic prokaryotes or their pathological action, and their use and preparation
DE102010013834A1 (en) 2008-03-30 2010-12-16 VLB Berlin e. V. Institut für Mikrobiologie Agent for blocking the growth or killing of bacteria, comprises phages, which contain a foreign gene for killing of the bacteria and/or a genetic modification for broadening of the host range and are Pf1 and/Pf3 phages
WO2010141135A2 (en) 2009-03-05 2010-12-09 Trustees Of Boston University Bacteriophages expressing antimicrobial peptides and uses thereof
WO2019068006A1 (en) * 2017-09-29 2019-04-04 The Charles Stark Draper Laboratory, Inc. Stimulus-controlled cell lysis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU699322B2 (en) * 1994-04-05 1998-12-03 Exponential Biotherapies, Inc. Antibacterial therapy with genotypically modified bacteriophage
WO1997039111A1 (en) * 1996-04-15 1997-10-23 Nymox Corporation Compositions containing bacteriophages and methods of using bacteriophages to treat infections
WO1998005344A1 (en) * 1996-08-05 1998-02-12 Brigham And Women's Hospital, Inc. Bacteriophage-mediated gene therapy
GB9908195D0 (en) * 1999-04-09 1999-06-02 Microbiological Res Authority Treatment of intracellular infection

Also Published As

Publication number Publication date
WO2002034892A1 (en) 2002-05-02

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