AU2001252438A1 - A modified expandase and uses thereof - Google Patents
A modified expandase and uses thereofInfo
- Publication number
- AU2001252438A1 AU2001252438A1 AU2001252438A AU5243801A AU2001252438A1 AU 2001252438 A1 AU2001252438 A1 AU 2001252438A1 AU 2001252438 A AU2001252438 A AU 2001252438A AU 5243801 A AU5243801 A AU 5243801A AU 2001252438 A1 AU2001252438 A1 AU 2001252438A1
- Authority
- AU
- Australia
- Prior art keywords
- modified expandase
- expandase
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/20—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and the other dehydrogenated (1.14.20)
- C12Y114/20001—Deacetoxycephalosporin-C synthase (1.14.20.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0011185 | 2000-05-09 | ||
GBGB0011185.6A GB0011185D0 (en) | 2000-05-09 | 2000-05-09 | Protein |
PCT/GB2001/002047 WO2001085951A1 (en) | 2000-05-09 | 2001-05-09 | A modified expandase and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001252438A1 true AU2001252438A1 (en) | 2001-11-20 |
Family
ID=9891262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001252438A Abandoned AU2001252438A1 (en) | 2000-05-09 | 2001-05-09 | A modified expandase and uses thereof |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2001252438A1 (en) |
GB (1) | GB0011185D0 (en) |
WO (1) | WO2001085951A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6699699B2 (en) * | 2002-03-26 | 2004-03-02 | Synmax Biochemical Co., Ltd. | Mutated penicillin expandases |
GB0319579D0 (en) * | 2003-08-20 | 2003-09-24 | Isis Innovation | Enzyme |
WO2005103261A1 (en) * | 2004-04-22 | 2005-11-03 | Orchid Chemicals & Pharmaceuticals Ltd. | Modified expandase enzyme and its use |
BRPI0515976A (en) * | 2004-10-13 | 2008-08-12 | Dsm Ip Assets Bv | mutant expandases |
EP1902140A2 (en) * | 2005-07-12 | 2008-03-26 | DSMIP Assets B.V. | Mutant expandases and their use in the production of beta-lactam compounds |
WO2007023369A1 (en) * | 2005-08-25 | 2007-03-01 | Orchid Chemicals & Pharmaceuticals Limited | Modified expandase-hydroxylase and its applications |
WO2008107782A2 (en) * | 2007-03-06 | 2008-09-12 | Orchid Chemicals & Pharmaceuticals Limited | Modified hydroxylase and its applications |
US9404139B2 (en) | 2012-01-10 | 2016-08-02 | Orchid Chemicals & Pharmaceuticals Limited | Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis |
CN107557348B (en) * | 2016-07-01 | 2022-07-08 | 百瑞全球有限公司 | Cephalosporin hydroxylase mutants, DNA encoding the same, methods of using the same and uses thereof |
CN112852912B (en) * | 2020-04-10 | 2022-01-11 | 中国科学院天津工业生物技术研究所 | Method for synthesizing 7-aminodesacetoxycephalosporanic acid |
CN114958877B (en) * | 2022-06-14 | 2024-02-20 | 河南省健康元生物医药研究院有限公司 | Deacetylated oxo cephalosporin C synthetase mutant, encoding gene and application thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997020053A2 (en) * | 1995-11-27 | 1997-06-05 | Gist-Brocades B.V. | Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g |
EP1047785A1 (en) * | 1997-12-24 | 2000-11-02 | Isis Innovation Limited | Modified deacetoxycephalosporin c synthase (daocs) and x-ray structure |
ID27054A (en) * | 1998-05-19 | 2001-02-22 | Dsm Nv | IMPROVING THE PRODUCTION OF SEPALOSPORIN IN LIVING ORGANISMS |
-
2000
- 2000-05-09 GB GBGB0011185.6A patent/GB0011185D0/en not_active Ceased
-
2001
- 2001-05-09 WO PCT/GB2001/002047 patent/WO2001085951A1/en active Application Filing
- 2001-05-09 AU AU2001252438A patent/AU2001252438A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GB0011185D0 (en) | 2000-06-28 |
WO2001085951A1 (en) | 2001-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2002235128A1 (en) | Expression miniarrays and uses thereof | |
AU4822301A (en) | Ready-to-eat rice and a preparation thereof | |
AU2001240637A1 (en) | Novel imidazotriazinones and the use thereof | |
AU2002211717A1 (en) | Stresscopins and their uses | |
AU2001272011A1 (en) | Siderophores-producing bifidobacteria thereby and uses thereof | |
AU2001292936A1 (en) | Octahydro-indolizines and quinolizines and hexahydro-pyrrolizines | |
AU2002243386A1 (en) | Rf2a and rf2b transcription factors | |
AUPQ342599A0 (en) | Conjugates and uses thereof | |
AU2001252438A1 (en) | A modified expandase and uses thereof | |
AU2001295185A1 (en) | Multiplexing-interleaving and demultiplexing-deinterleaving | |
AU2002224876A1 (en) | Isolated luciferases and the use thereof | |
AU2002228921A1 (en) | Arcelin-5 promoter and uses thereof | |
AU2001252062A1 (en) | Steatosis-modulating factors and uses thereof | |
AU2001269276A1 (en) | Drills and their manufacture | |
AU2002256556A1 (en) | Sea-trosy and related methods | |
AU5979300A (en) | Angiopoietin-6 and uses thereof | |
AU2001259191A1 (en) | 25692, a novel human o-methyltransferase family member and uses thereof | |
AU3145999A (en) | A and b apicularene | |
AU2002213398A1 (en) | Expression vectors and uses thereof | |
AU6042601A (en) | Compounds and their uses | |
AU2001253285A1 (en) | Gp40 and uses thereof | |
AU2001241928A1 (en) | Transferase 32253 and use therefor | |
AU5054501A (en) | Acetyltransferase and uses thereof | |
AU2001286999A1 (en) | 27439, a human hydroxylase and uses therefor | |
AU2002211098A1 (en) | A polyester and a toner composition |