AU2002219935A1 - Polyalkylene glycol viscosity-enhancing polymeric formulations - Google Patents
Polyalkylene glycol viscosity-enhancing polymeric formulationsInfo
- Publication number
- AU2002219935A1 AU2002219935A1 AU2002219935A AU1993502A AU2002219935A1 AU 2002219935 A1 AU2002219935 A1 AU 2002219935A1 AU 2002219935 A AU2002219935 A AU 2002219935A AU 1993502 A AU1993502 A AU 1993502A AU 2002219935 A1 AU2002219935 A1 AU 2002219935A1
- Authority
- AU
- Australia
- Prior art keywords
- viscosity
- tissue
- polyalkylene glycol
- mixture
- hyaluronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/043—Mixtures of macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
Abstract
Hyaluronic acid and polyalkylene glycol (PAG) based materials have been found to exhibit a synergistic interaction, in which the viscosity of the mixture is more than twice as high as the viscosity expected from the viscosity of the individual components. The mixture otherwise has similar properties to those of its constituents, and in particular will crosslink to form covalently crosslinked gels if the PEG carries crosslinkable groups. The viscous formulation adheres well to tissue, and has applications as a tissue sealant and in tissue coating, prevention of adhesions, cell immobilization, regeneration of cartilage, bone and other tissue, as well as in controlled delivery of hyaluronic acid to sites in the body. Related materials exhibit similar effects.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25347700P | 2000-11-28 | 2000-11-28 | |
US60/253,477 | 2000-11-28 | ||
PCT/US2001/044769 WO2002044276A2 (en) | 2000-11-28 | 2001-11-28 | Polyalkylene glycol viscosity-enhancing polymeric formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002219935A1 true AU2002219935A1 (en) | 2002-06-11 |
Family
ID=22960435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002219935A Abandoned AU2002219935A1 (en) | 2000-11-28 | 2001-11-28 | Polyalkylene glycol viscosity-enhancing polymeric formulations |
Country Status (8)
Country | Link |
---|---|
US (1) | US7074424B2 (en) |
EP (1) | EP1370610B1 (en) |
JP (1) | JP2004514778A (en) |
AT (1) | ATE407975T1 (en) |
AU (1) | AU2002219935A1 (en) |
CA (1) | CA2430130A1 (en) |
DE (1) | DE60135784D1 (en) |
WO (1) | WO2002044276A2 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR039744A1 (en) * | 2002-06-26 | 2005-03-09 | Alza Corp | METHODS AND DOSAGE FORMS TO INCREASE THE SOLUBILITY OF PHARMACOS COMPOSITIONS FOR CONTROLLED ADMINISTRATION |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
NZ537543A (en) * | 2002-07-29 | 2007-08-31 | Alza Corp | Formulations and high dose osmotic dosage forms for controlled delivery of topiramate |
US6992127B2 (en) * | 2002-11-25 | 2006-01-31 | Ast Products, Inc. | Polymeric coatings containing a pH buffer agent |
EP1659143A4 (en) * | 2003-07-28 | 2008-10-08 | Teijin Ltd | Temperature-responsive hydrogel |
AU2004264316A1 (en) * | 2003-08-06 | 2005-02-24 | Alza Corporation | Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation |
US20050136108A1 (en) * | 2003-08-22 | 2005-06-23 | Yam Noymi V. | Stepwise delivery of topiramate over prolonged period of time |
CA2550699A1 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation, Inc. | Novel drug compositions and dosage forms of topiramate |
US20050175696A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Drug granule coatings that impart smear resistance during mechanical compression |
JP2007517061A (en) * | 2003-12-29 | 2007-06-28 | アルザ・コーポレーシヨン | Novel pharmaceutical composition and dosage form |
US8288362B2 (en) | 2004-05-07 | 2012-10-16 | S.K. Pharmaceuticals, Inc. | Stabilized glycosaminoglycan preparations and related methods |
JP2007536277A (en) * | 2004-05-07 | 2007-12-13 | エスケイ ファーマシューティカルズ インコーポレイテッド | Stabilized hyaluronan preparation and method thereof |
US20050281866A1 (en) * | 2004-05-24 | 2005-12-22 | Genzyme Corporation | Adherent polymeric compositions |
US20060140988A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Visco-supplement composition and methods |
US9119901B2 (en) | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
US8414907B2 (en) * | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
EP1940468B1 (en) * | 2005-09-07 | 2017-11-15 | AMO Regional Holdings | Bi-modal hyaluronate solution |
ES2285910B1 (en) * | 2005-09-08 | 2008-12-16 | Vicente Tormo Maicas | PROCEDURE FOR THE ELABORATION OF THE FORMULA OF SODIUM HYALURONATE FOR THE HEALING AND CICATRIZATION OF WOUNDS. |
CA2628579C (en) * | 2005-12-06 | 2014-07-08 | Tyco Healthcare Group Lp | Carbodiimide crosslinking of functionalized polethylene glycols |
GB0608359D0 (en) * | 2006-04-28 | 2006-06-07 | Johnson Matthey Plc | Catalyst additives |
AR062046A1 (en) * | 2006-07-25 | 2008-08-10 | Osmotica Pharmaceutical Argentina S A | OPHTHALMIC SOLUTIONS |
US20090105561A1 (en) * | 2007-10-17 | 2009-04-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
BRPI1006076B8 (en) | 2009-01-13 | 2021-05-25 | Pergamum Ab | pharmaceutical compositions |
KR20130101974A (en) | 2010-04-16 | 2013-09-16 | 아파테크 리미티드 | Biomaterial |
US20110274666A1 (en) * | 2010-05-07 | 2011-11-10 | University Of North Carolina At Chapel Hill | Method of engrafting cells from solid tissues |
CN102988274B (en) * | 2010-09-08 | 2015-01-28 | 上海市肿瘤研究所 | Sustained-release blood vessel embolic gel used for treating tumor, and preparation method thereof |
TWI413535B (en) * | 2010-12-09 | 2013-11-01 | Yung Kai Lin | Thremosensitivity hydrogel for tissue engineering and use thereof |
TWI544922B (en) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | High concentration olopatadine ophthalmic composition |
WO2013006671A2 (en) | 2011-07-05 | 2013-01-10 | The Research Foundation Of State University Of New York | Compositions and methods for spinal disc repair and other surgical and non-surgical indications |
KR101269423B1 (en) * | 2011-12-22 | 2013-05-30 | 오스템임플란트 주식회사 | Hydrogel with controllable biodegradation behavior and the manufacturing method thereof |
US9827321B2 (en) | 2012-08-14 | 2017-11-28 | The Trustees Of The University Of Pennsylvania | Stabilizing shear-thinning hydrogels |
US11639416B2 (en) | 2018-04-19 | 2023-05-02 | Poly-Med, Inc. | Macromers and compositions for photocuring processes |
EP3969070A4 (en) * | 2019-05-13 | 2022-07-06 | University of Pittsburgh - of the Commonwealth System of Higher Education | Polymer-based implant for retinal therapy and methods of making and using the same |
US20210094226A1 (en) * | 2019-09-26 | 2021-04-01 | The Curators Of The University Of Missouri | Oxidation polymerization additive manufacturing |
CN116077731A (en) * | 2021-11-05 | 2023-05-09 | 重庆医科大学附属口腔医院 | Tissue repair material based on giant salamander skin secretion and application thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3325472A (en) * | 1964-06-18 | 1967-06-13 | Mortimer D Sackler | Polycyclohexose-polyoxyethyleneglycol suppository bases |
LU85582A1 (en) | 1983-10-11 | 1985-06-04 | Fidia Spa | HYALURONIC ACID FRACTIONS HAVING PHARMACEUTICAL ACTIVITY, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
US4629623A (en) | 1984-06-11 | 1986-12-16 | Biomatrix, Inc. | Hyaluronate-poly (ethylene oxide) compositions and cosmetic formulations thereof |
US5068225A (en) * | 1987-05-04 | 1991-11-26 | Mdr Group, Inc. | Viscoelastic fluid for use in surgery and other therapies and method of using same |
US5510418A (en) | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
US5143724A (en) | 1990-07-09 | 1992-09-01 | Biomatrix, Inc. | Biocompatible viscoelastic gel slurries, their preparation and use |
US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
JP4209941B2 (en) | 1995-03-23 | 2009-01-14 | ジェンザイム・コーポレーション | Undercoat redox and photoinitiator systems for improved adhesion of gels to substrates |
ZA978537B (en) * | 1996-09-23 | 1998-05-12 | Focal Inc | Polymerizable biodegradable polymers including carbonate or dioxanone linkages. |
US6123667A (en) * | 1997-03-20 | 2000-09-26 | Focal, Inc. | Retracting tissue using photoadhering adhesive |
US5906997A (en) | 1997-06-17 | 1999-05-25 | Fzio Med, Inc. | Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions |
FR2780730B1 (en) * | 1998-07-01 | 2000-10-13 | Corneal Ind | INJECTABLE BIPHASIC COMPOSITIONS, ESPECIALLY USEFUL IN RESTORATIVE AND AESTHETIC SURGERIES |
KR100698559B1 (en) | 1999-06-11 | 2007-03-21 | 넥타르 테라퓨틱스 에이엘, 코포레이션 | Hydrogels derived from chitosan and polyethylene glycol or related polymers |
US6288043B1 (en) * | 1999-06-18 | 2001-09-11 | Orquest, Inc. | Injectable hyaluronate-sulfated polysaccharide conjugates |
US6685883B2 (en) | 1999-08-27 | 2004-02-03 | Tetra Laval Holdings & Finance S.A. | Method and unit for sterilizing packaging sheet material for manufacturing sealed packages of pourable food products |
-
2001
- 2001-11-28 US US09/996,184 patent/US7074424B2/en not_active Expired - Lifetime
- 2001-11-28 AU AU2002219935A patent/AU2002219935A1/en not_active Abandoned
- 2001-11-28 AT AT01998596T patent/ATE407975T1/en not_active IP Right Cessation
- 2001-11-28 WO PCT/US2001/044769 patent/WO2002044276A2/en active Application Filing
- 2001-11-28 EP EP01998596A patent/EP1370610B1/en not_active Revoked
- 2001-11-28 DE DE60135784T patent/DE60135784D1/en not_active Expired - Lifetime
- 2001-11-28 JP JP2002546630A patent/JP2004514778A/en active Pending
- 2001-11-28 CA CA002430130A patent/CA2430130A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2004514778A (en) | 2004-05-20 |
WO2002044276A3 (en) | 2003-03-20 |
EP1370610B1 (en) | 2008-09-10 |
WO2002044276A2 (en) | 2002-06-06 |
US20020127196A1 (en) | 2002-09-12 |
DE60135784D1 (en) | 2008-10-23 |
US7074424B2 (en) | 2006-07-11 |
CA2430130A1 (en) | 2002-06-06 |
ATE407975T1 (en) | 2008-09-15 |
EP1370610A2 (en) | 2003-12-17 |
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