AU2002214336A1 - Pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease - Google Patents

Pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease

Info

Publication number
AU2002214336A1
AU2002214336A1 AU2002214336A AU1433602A AU2002214336A1 AU 2002214336 A1 AU2002214336 A1 AU 2002214336A1 AU 2002214336 A AU2002214336 A AU 2002214336A AU 1433602 A AU1433602 A AU 1433602A AU 2002214336 A1 AU2002214336 A1 AU 2002214336A1
Authority
AU
Australia
Prior art keywords
treatment
pharmaceutical preparations
preparations containing
prevention
neurodegenerative disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002214336A
Inventor
Gyeong-A Gu
Won-Ju Jeong
So-Ra Kim
Young-Joong Kim
Mi-Gyeong Lee
Sang-Hyun Sung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elcom Bio Technology Co Ltd
Original Assignee
Elcom Bio Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elcom Bio Technology Co Ltd filed Critical Elcom Bio Technology Co Ltd
Publication of AU2002214336A1 publication Critical patent/AU2002214336A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to the use of a dibenzocyclooctane lignan derivative of the following general formula (I) for treatment of neurodegenerative disorders:wherein R1 is H or C1-4 lower alkyl; R2, R3, R4 and R5 are respectively H, OH, C1-4 lower alkyl, C1-4 lower alkoxy, or R2 and R3 or R4 and R5 are respectively combined to form the group of -OCH2O-. Pharmaceutical preparations containing the dibenzocyclooctane lignan derivative as the active ingredient also are disclosed.
AU2002214336A 2000-10-19 2001-10-19 Pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease Abandoned AU2002214336A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR0061676 2000-10-19
KR10-2000-0061676A KR100380634B1 (en) 2000-10-19 2000-10-19 Composition containing a dibenzocyclooctane lignan derivative for prevention or treatment of neurodegenerative disease
PCT/KR2001/001765 WO2002032417A1 (en) 2000-10-19 2001-10-19 Pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease

Publications (1)

Publication Number Publication Date
AU2002214336A1 true AU2002214336A1 (en) 2002-04-29

Family

ID=19694389

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002214336A Abandoned AU2002214336A1 (en) 2000-10-19 2001-10-19 Pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease

Country Status (9)

Country Link
US (1) US6653344B2 (en)
EP (1) EP1326596B1 (en)
JP (1) JP3996505B2 (en)
KR (1) KR100380634B1 (en)
CN (1) CN1171585C (en)
AT (1) ATE437636T1 (en)
AU (1) AU2002214336A1 (en)
DE (1) DE60139409D1 (en)
WO (1) WO2002032417A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002212774A1 (en) * 2000-10-19 2002-04-29 Elcom Bio Technology, Co., Ltd. Saururus chinensis extract for prevention and treatment of neurodegenerative disease
KR100569089B1 (en) * 2002-07-20 2006-04-10 주식회사 엘컴사이언스 Composition having brain function and congnition enhancing activity
KR100679306B1 (en) 2005-03-31 2007-02-06 아미코젠주식회사 Pharmaceutical composition for treating or preventing a neurological brain disease comprising lignan compounds
KR100752750B1 (en) * 2005-07-11 2007-08-29 최영환 Schisandrene extracted from Schisandra chinensis and antioxidant composition comprising it as an active ingredient
KR100781581B1 (en) 2006-05-11 2007-12-03 김호철 Pharmaceutical composition comprising gomisin-? as an effective ingredient showing neuro-protective activity
EP2025335A1 (en) * 2007-08-16 2009-02-18 InterMed Discovery GmbH Extracts with liver-X-receptor modulators, compounds and their use in weight control and treatment of disorders of lipid metabolism
WO2012045400A1 (en) * 2010-10-05 2012-04-12 Cognis Ip Management Gmbh An extract of the fruit of the plant schisandra chinensis
CN104151373B (en) * 2013-05-13 2017-01-18 四川万安石斛产业开发有限公司 Lignan glycoside compounds and preparation method thereof
CN106939009A (en) * 2017-03-31 2017-07-11 牡丹江医学院 It is a kind of to be used to treat medicine of cerebral concussion and preparation method thereof
KR102147794B1 (en) 2018-11-12 2020-08-25 서울대학교 산학협력단 Composition for treating Neurodegenerative diseases comprising Mixture of Tomato and Lemon Extracts
CN115919837A (en) * 2022-08-17 2023-04-07 浙江中医药大学 Application of gomisin N in preparation of medicine for treating ischemic cerebral apoplexy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6222714A (en) * 1985-07-22 1987-01-30 Tsumura Juntendo Inc Lipid metabolism promoter
JPS6416721A (en) * 1987-07-09 1989-01-20 Tsumura & Co Antioxidant
JPS6442421A (en) * 1987-08-10 1989-02-14 Tsumura & Co Calcium antagonistic agent
JPH01316313A (en) * 1988-03-17 1989-12-21 Tsumura & Co Agent for ameliorating cerebral function

Also Published As

Publication number Publication date
CN1171585C (en) 2004-10-20
JP3996505B2 (en) 2007-10-24
WO2002032417A1 (en) 2002-04-25
DE60139409D1 (en) 2009-09-10
EP1326596A4 (en) 2005-11-23
EP1326596A1 (en) 2003-07-16
US6653344B2 (en) 2003-11-25
ATE437636T1 (en) 2009-08-15
KR20020030642A (en) 2002-04-25
CN1394137A (en) 2003-01-29
JP2004511514A (en) 2004-04-15
KR100380634B1 (en) 2003-04-26
US20030050335A1 (en) 2003-03-13
EP1326596B1 (en) 2009-07-29

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