AU2002214189A1 - Methods of identifying inhibitory compounds and uses thereof - Google Patents

Methods of identifying inhibitory compounds and uses thereof

Info

Publication number
AU2002214189A1
AU2002214189A1 AU2002214189A AU1418902A AU2002214189A1 AU 2002214189 A1 AU2002214189 A1 AU 2002214189A1 AU 2002214189 A AU2002214189 A AU 2002214189A AU 1418902 A AU1418902 A AU 1418902A AU 2002214189 A1 AU2002214189 A1 AU 2002214189A1
Authority
AU
Australia
Prior art keywords
methods
inhibitory compounds
identifying inhibitory
identifying
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002214189A
Inventor
Stephan Kellenberger
Laurent Schild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Lausanne
Original Assignee
Universite de Lausanne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Lausanne filed Critical Universite de Lausanne
Publication of AU2002214189A1 publication Critical patent/AU2002214189A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G01N33/04—Dairy products
AU2002214189A 2000-09-20 2001-09-20 Methods of identifying inhibitory compounds and uses thereof Abandoned AU2002214189A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23402100P 2000-09-20 2000-09-20
US60/234,021 2000-09-20
US09/956,522 2001-09-19
US09/956,522 US20020128203A1 (en) 2000-09-20 2001-09-19 Methods of identifying inhibitory compounds and uses thereof
PCT/IB2001/002120 WO2002024177A2 (en) 2000-09-20 2001-09-20 Methods of identifying inhibitory compounds and uses thereof

Publications (1)

Publication Number Publication Date
AU2002214189A1 true AU2002214189A1 (en) 2002-04-02

Family

ID=26927474

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002214189A Abandoned AU2002214189A1 (en) 2000-09-20 2001-09-20 Methods of identifying inhibitory compounds and uses thereof

Country Status (3)

Country Link
US (1) US20020128203A1 (en)
AU (1) AU2002214189A1 (en)
WO (1) WO2002024177A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4969002B2 (en) * 1999-06-08 2012-07-04 ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン Compounds and methods for increasing rAAV transduction
US7241447B1 (en) * 1999-10-07 2007-07-10 University Of Iowa Research Foundation Adeno-associated virus vectors and uses thereof
US10078087B2 (en) 2001-05-01 2018-09-18 Senomyx, Inc. Assays and enhancers of the human delta ENaC sodium channel
EP1608763A2 (en) * 2003-03-31 2005-12-28 University Of Iowa Research Foundation Compounds and methods to enhance raav transduction
JP2007528712A (en) * 2003-07-10 2007-10-18 セノミックス、インコーポレイテッド Use of phenamyl to improve the efficacy of ENaC synergists in improved electrophysiological assays using human ENaC expressing oocytes and assays using membrane potential reporter dyes
SE0402832D0 (en) * 2004-11-18 2004-11-18 Astrazeneca Ab Methods
AU2007243184A1 (en) * 2006-04-28 2007-11-08 University Of Iowa Research Foundation Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor
US11702672B2 (en) 2016-02-08 2023-07-18 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
EP3426787A1 (en) 2016-03-07 2019-01-16 University of Iowa Research Foundation Aav-mediated expression using a synthetic promoter and enhancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234922A (en) * 1992-09-28 1993-08-10 University Of Iowa Research Foundation Use of sulfonylureas and other potassium channel regulators to treat secretory diarrhea
US5780242A (en) * 1993-06-18 1998-07-14 Nickel; Alfred A. Bioassay for the screening of ION channel active molecules
US5437982A (en) * 1993-09-08 1995-08-01 University Of Washington Methods of identifying specific inactivation gate inhibitors of the sodium channel
US5693756A (en) * 1994-02-28 1997-12-02 The Johns Hopkins University Amiloride-sensitive sodium channel and method of identifying substances which stimulate or block salty taste perception
US5892018A (en) * 1996-04-02 1999-04-06 Welsh; Michael J. DNA sequences encoding a brain sodium channel protein
ES2225979T3 (en) * 1996-07-22 2005-03-16 Daiichi Suntory Pharma Co., Ltd. DERIVATIVES OF ARILPIPERIDINOL AND ARILPIPERIDINE AND PHARMACOS CONTAINING THEM.
US6551775B1 (en) * 1997-03-11 2003-04-22 Yale University Method to diagnose and treat pathological conditions resulting from deficient ion transport such as pseudohypoaldosteronism type-1
DE19907385A1 (en) * 1999-02-20 2000-08-24 Boehringer Ingelheim Pharma New 3-(phenoxy or phenylalkoxy)-2-phenyl-propylamines, useful for treating e.g. arrhythmia, spasms, pain or neurodegenerative diseases, are tension-dependent sodium channel blockers

Also Published As

Publication number Publication date
US20020128203A1 (en) 2002-09-12
WO2002024177A3 (en) 2003-03-13
WO2002024177A2 (en) 2002-03-28

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