AU2002211464A1 - Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitors - Google Patents
Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitorsInfo
- Publication number
- AU2002211464A1 AU2002211464A1 AU2002211464A AU2002211464A AU2002211464A1 AU 2002211464 A1 AU2002211464 A1 AU 2002211464A1 AU 2002211464 A AU2002211464 A AU 2002211464A AU 2002211464 A AU2002211464 A AU 2002211464A AU 2002211464 A1 AU2002211464 A1 AU 2002211464A1
- Authority
- AU
- Australia
- Prior art keywords
- alkoxyguanidinyl
- aminoguanidinyl
- aminopyridinyl
- substituted phenyl
- protease inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FZERHIULMFGESH-UHFFFAOYSA-N Acetanilide Chemical class CC(=O)NC1=CC=CC=C1 FZERHIULMFGESH-UHFFFAOYSA-N 0.000 title 1
- -1 Aminopyridinyl- Chemical group 0.000 title 1
- 229940042399 direct acting antivirals Protease inhibitors Drugs 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23813200P | 2000-10-06 | 2000-10-06 | |
| US60/238,132 | 2000-10-06 | ||
| PCT/US2001/031249 WO2002028825A2 (en) | 2000-10-06 | 2001-10-05 | Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002211464A1 true AU2002211464A1 (en) | 2002-06-27 |
| AU2002211464B2 AU2002211464B2 (en) | 2006-06-22 |
Family
ID=22896640
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002211464A Ceased AU2002211464B2 (en) | 2000-10-06 | 2001-10-05 | Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitors |
| AU1146402A Pending AU1146402A (en) | 2000-10-06 | 2001-10-05 | Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU1146402A Pending AU1146402A (en) | 2000-10-06 | 2001-10-05 | Aminopyridinyl-, aminoguanidinyl- and alkoxyguanidinyl- substituted phenyl acetamides as protease inhibitors |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US6521663B2 (en) |
| EP (1) | EP1324981B1 (en) |
| JP (1) | JP4256160B2 (en) |
| KR (1) | KR20030045103A (en) |
| CN (1) | CN1315803C (en) |
| AT (1) | ATE337299T1 (en) |
| AU (2) | AU2002211464B2 (en) |
| BR (1) | BR0114263A (en) |
| CA (1) | CA2423883A1 (en) |
| CY (1) | CY1106243T1 (en) |
| DE (1) | DE60122546T2 (en) |
| DK (1) | DK1324981T3 (en) |
| ES (1) | ES2269474T3 (en) |
| HK (1) | HK1058032A1 (en) |
| HR (1) | HRP20030252A2 (en) |
| HU (1) | HUP0303149A3 (en) |
| IL (1) | IL155160A0 (en) |
| MX (1) | MXPA03002998A (en) |
| NO (1) | NO20031390L (en) |
| NZ (1) | NZ525438A (en) |
| PL (1) | PL361185A1 (en) |
| PT (1) | PT1324981E (en) |
| RU (1) | RU2003113205A (en) |
| UA (1) | UA75093C2 (en) |
| WO (1) | WO2002028825A2 (en) |
| ZA (1) | ZA200303091B (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| UA75093C2 (en) * | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| US6610701B2 (en) * | 2001-02-09 | 2003-08-26 | Merck & Co., Inc. | Thrombin inhibitors |
| US6984645B2 (en) * | 2001-11-16 | 2006-01-10 | Bristol-Myers Squibb Company | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein |
| US7759513B2 (en) * | 2003-02-21 | 2010-07-20 | Nigu Chemie Gmbh | Photolabile protective groups for improved processes to prepare oligonucleotide arrays |
| US7550474B2 (en) | 2003-04-10 | 2009-06-23 | Johnson & Johnson Pharmaceuticals Research & Development, L.L.C. | Substituted phenyl acetamides and their use as protease inhibitors |
| US7427683B2 (en) * | 2003-04-25 | 2008-09-23 | Ortho-Mcneil Pharmaceutical, Inc. | c-fms kinase inhibitors |
| US7790724B2 (en) | 2003-04-25 | 2010-09-07 | Janssen Pharmaceutica N.V. | c-fms kinase inhibitors |
| JP2007525460A (en) | 2003-04-25 | 2007-09-06 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | c-fms kinase inhibitor |
| US7914705B2 (en) * | 2005-01-10 | 2011-03-29 | Robert Eliot Sisson | Flowable electrical conductive liquid |
| HU0500126D0 (en) * | 2005-01-26 | 2005-04-28 | Sanofi Aventis | New compounds and process for their preparation |
| MX2007016090A (en) * | 2005-06-17 | 2008-03-10 | Astrazeneca Ab | Thrombin inhibiting 2-oxo-1, 2, 5, 6-tetrahydropyridine derivatives. |
| PL2010493T3 (en) * | 2006-04-12 | 2016-08-31 | Merck Sharp & Dohme | Pyridyl amide t-type calcium channel antagonists |
| RU2353619C2 (en) * | 2007-06-28 | 2009-04-27 | Общество С Ограниченной Ответственностью "Бионика" | Novel compounds possessing anticoagulant function, based on them pharmaceutical compositions for treatment of thrombotic conditions and plasma-substituting solution for correction of hypercoagulation disorders in hemodilution |
| RU2354647C2 (en) * | 2007-06-28 | 2009-05-10 | Общество С Ограниченной Ответственностью "Бионика" | New compounds with thrombin inhibiting function, and based pharmaceutical compositions |
| CN101665465B (en) * | 2007-09-19 | 2011-09-07 | 复旦大学 | Thrombase inhibitor containing guanidyl heterocyclic compound and preparation method thereof |
| WO2009054984A1 (en) * | 2007-10-24 | 2009-04-30 | Merck & Co., Inc. | Heterocycle phenyl amide t-type calcium channel antagonists |
| BR112013013414B1 (en) | 2010-12-02 | 2023-01-10 | Becton, Dickinson And Company | DEVICE FOR COLLECTING AND STABILIZING BLOOD OR A COMPONENT THEREOF, USES OF SAID DEVICE AND KIT COMPRISING THE SAME |
| CN110123820B (en) | 2010-12-31 | 2022-05-31 | 阿斯利康公司 | Arginase inhibitors and methods of use thereof |
| US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
| AU2012255137A1 (en) | 2011-05-17 | 2013-12-12 | The Brigham And Women's Hospital, Inc. | Improved platelet storage using a sialidase inhibitor |
| US9609861B2 (en) | 2011-05-17 | 2017-04-04 | Velico Medical Inc. | Platelet additive solution having a β-galactosidase inhibitor |
| RU2524647C1 (en) * | 2012-12-25 | 2014-07-27 | Государственное Бюджетное Учреждение Санкт-Петербургский Научно-Исследовательский Институт Скорой Помощи Им. И.И. Джанелидзе" | Method of treating endogenous intoxication syndrome caused by hyperproteolysis |
| WO2014120886A1 (en) | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
| WO2015143376A1 (en) * | 2014-03-21 | 2015-09-24 | Nivalis Therapeutics, Inc. | Novel compounds for the treatment of cystic fibrosis |
| WO2017015495A1 (en) * | 2015-07-21 | 2017-01-26 | Immunogen, Inc. | Methods of preparing cytotoxic benzodiazepine derivatives |
| JP2020520981A (en) * | 2017-05-24 | 2020-07-16 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドＲａｍｏｔ Ａｔ Ｔｅｌ Ａｖｉｖ Ｕｎｉｖｅｒｓｉｔｙ Ｌｔｄ． | Chemiluminescent probe for imaging/detection of proteases |
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|---|---|---|---|---|
| US5084466A (en) | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| CA2075154A1 (en) * | 1991-08-06 | 1993-02-07 | Neelakantan Balasubramanian | Peptide aldehydes as antithrombotic agents |
| DE4208051A1 (en) | 1992-03-13 | 1993-09-16 | Bayer Ag | SUBSTITUTED PHENYL ACIDIC ACID AMIDE |
| DE4319887A1 (en) | 1993-06-16 | 1994-12-22 | Hoechst Schering Agrevo Gmbh | Arylacetamides, processes for their preparation, compositions containing them and their use as fungicides |
| DE69432019T2 (en) | 1993-08-12 | 2003-11-27 | Astrazeneca Ab, Soedertaelje | AMIDINE DERIVATIVES WITH NITROGEN OXIDE SYNTHEASE ACTIVITY |
| US5885967A (en) | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
| JPH0892224A (en) | 1994-09-16 | 1996-04-09 | Kumiai Chem Ind Co Ltd | 3,5-substituted phenyltriazole derivative and insecticide/ miticide |
| JP3570752B2 (en) | 1994-09-22 | 2004-09-29 | 三井化学株式会社 | 4-Substituted carbonyl coumarin derivative and visible light-sensitive composition using the same |
| DE19507822B4 (en) | 1995-02-21 | 2006-07-20 | Schering Ag | Substituted DTPA monoamides of the central carboxylic acid and its metal complexes, pharmaceutical compositions containing these complexes, their use in diagnostics and therapy, and methods for the preparation of the complexes and agents |
| US5741819A (en) * | 1995-06-07 | 1998-04-21 | 3-Dimensional Pharmaceuticals, Inc. | Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors |
| US5721214A (en) | 1995-06-07 | 1998-02-24 | Cor Therapeutics, Inc. | Inhibitors of factor Xa |
| CA2224437A1 (en) * | 1995-06-27 | 1997-01-16 | Merck & Co., Inc. | Pyridinone-thrombin inhibitors |
| HUP9802764A3 (en) | 1995-09-29 | 2000-03-28 | Dimensional Pharm Inc | Guanidino protease inhibitors |
| DE69717268T2 (en) | 1996-02-22 | 2003-09-04 | Bristol-Myers Squibb Pharma Co., Wilmington | M-AMIDINOPHENYL ANALOGUE AS FACTOR XA INHIBITORS |
| DE19615262A1 (en) | 1996-04-18 | 1997-10-23 | Bayer Ag | Hetero-linked phenylglycinolamides |
| US5863929A (en) | 1996-06-25 | 1999-01-26 | Eli Lilly And Company | Anticoagulant agents |
| US6174905B1 (en) | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
| DE19642863A1 (en) | 1996-10-17 | 1998-04-23 | Bayer Ag | Amides |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| GB9703201D0 (en) | 1997-02-15 | 1997-04-02 | Zeneca Ltd | Chemical compounds |
| PT966436E (en) | 1997-02-21 | 2003-03-31 | Bayer Ag | ARILSULFONAMIDES AND ANALOGS AND THEIR APPLICATION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES |
| US6049006A (en) | 1997-06-16 | 2000-04-11 | American Home Products Corp. | Elevation of HDL cholesterol by N-[2-[(aminothioxomethyl) hydrazono]-2-arylethyl]amides |
| US6034272A (en) | 1997-06-16 | 2000-03-07 | American Home Products Corporation | Elevation of HDL cholesterol by N-[4-[(aminothioxomethyl) hydrazono]-4-arylbutyl]amides |
| AU7498298A (en) | 1997-06-16 | 1999-01-04 | American Home Products Corporation | Elevation of hdl cholesterol by n-{2-{ (aminothioxomethyl)hydrazono} -2-arylethyl}amides |
| AU7691298A (en) | 1997-06-16 | 1999-01-04 | American Home Products Corporation | Elevation of hdl cholesterol by n-{4-{ (aminothioxomethyl) hydrazono} -4-arylbutyl}amides |
| EP1036063B1 (en) * | 1997-11-26 | 2006-11-02 | Ortho-McNeil Pharmaceuticals, Inc. | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors |
| CA2260499A1 (en) | 1998-01-29 | 1999-07-29 | Sumitomo Pharmaceuticals Company Limited | Pharmaceutical compositions for the treatment of ischemic brain damage |
| US6344486B1 (en) * | 1998-04-03 | 2002-02-05 | 3-Dimensional Pharmaceuticals, Inc. | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors |
| US6458781B1 (en) | 1998-04-27 | 2002-10-01 | David Thomas Connor | Substituted diarylalkyl amides as calcium channel antagonists |
| DE19824470A1 (en) | 1998-05-30 | 1999-12-02 | Boehringer Ingelheim Pharma | Novel neurokine antagonists, processes for their preparation and pharmaceutical compositions containing these compounds |
| DE19937494A1 (en) * | 1999-08-07 | 2001-02-08 | Boehringer Ingelheim Pharma | New carboxylic acid amides are Factor Xa and serine protease inhibitors, useful for the treatment and prevention of thrombotic disorders, tumors and fibrin-dependent inflammation |
| AU2001243598A1 (en) | 2000-03-13 | 2001-09-24 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade |
| UA75093C2 (en) * | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
-
2001
- 2001-05-10 UA UA2003054058A patent/UA75093C2/en unknown
- 2001-10-05 BR BR0114263-1A patent/BR0114263A/en not_active IP Right Cessation
- 2001-10-05 PL PL36118501A patent/PL361185A1/en not_active Application Discontinuation
- 2001-10-05 RU RU2003113205/04A patent/RU2003113205A/en not_active Application Discontinuation
- 2001-10-05 CA CA002423883A patent/CA2423883A1/en not_active Abandoned
- 2001-10-05 PT PT01979513T patent/PT1324981E/en unknown
- 2001-10-05 US US09/971,000 patent/US6521663B2/en not_active Expired - Lifetime
- 2001-10-05 MX MXPA03002998A patent/MXPA03002998A/en active IP Right Grant
- 2001-10-05 AU AU2002211464A patent/AU2002211464B2/en not_active Ceased
- 2001-10-05 WO PCT/US2001/031249 patent/WO2002028825A2/en active Application Filing
- 2001-10-05 ZA ZA200303091A patent/ZA200303091B/en unknown
- 2001-10-05 HU HU0303149A patent/HUP0303149A3/en unknown
- 2001-10-05 AU AU1146402A patent/AU1146402A/en active Pending
- 2001-10-05 ES ES01979513T patent/ES2269474T3/en not_active Expired - Lifetime
- 2001-10-05 IL IL15516001A patent/IL155160A0/en unknown
- 2001-10-05 NZ NZ525438A patent/NZ525438A/en unknown
- 2001-10-05 EP EP01979513A patent/EP1324981B1/en not_active Expired - Lifetime
- 2001-10-05 KR KR10-2003-7004831A patent/KR20030045103A/en not_active Application Discontinuation
- 2001-10-05 DE DE60122546T patent/DE60122546T2/en not_active Expired - Fee Related
- 2001-10-05 CN CNB018182542A patent/CN1315803C/en not_active Expired - Fee Related
- 2001-10-05 AT AT01979513T patent/ATE337299T1/en not_active IP Right Cessation
- 2001-10-05 DK DK01979513T patent/DK1324981T3/en active
- 2001-10-05 JP JP2002532411A patent/JP4256160B2/en not_active Expired - Fee Related
-
2002
- 2002-10-03 US US10/262,871 patent/US6900231B2/en not_active Expired - Lifetime
-
2003
- 2003-03-26 NO NO20031390A patent/NO20031390L/en not_active Application Discontinuation
- 2003-04-03 HR HR20030252A patent/HRP20030252A2/en not_active Application Discontinuation
-
2004
- 2004-01-02 HK HK0100042A patent/HK1058032A1/en not_active IP Right Cessation
-
2005
- 2005-01-10 US US11/032,297 patent/US20050159457A1/en not_active Abandoned
-
2006
- 2006-11-14 CY CY20061101657T patent/CY1106243T1/en unknown
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