AU2001297015A1 - Improved ligand binding assays for vanilloid receptors - Google Patents

Improved ligand binding assays for vanilloid receptors

Info

Publication number
AU2001297015A1
AU2001297015A1 AU2001297015A AU9701501A AU2001297015A1 AU 2001297015 A1 AU2001297015 A1 AU 2001297015A1 AU 2001297015 A AU2001297015 A AU 2001297015A AU 9701501 A AU9701501 A AU 9701501A AU 2001297015 A1 AU2001297015 A1 AU 2001297015A1
Authority
AU
Australia
Prior art keywords
ligand
vanilloid receptor
protein
receptor
test compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001297015A
Other languages
English (en)
Inventor
Ellen E. Codd
Sui-Po Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of AU2001297015A1 publication Critical patent/AU2001297015A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polarising Elements (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001297015A 2000-10-15 2001-10-11 Improved ligand binding assays for vanilloid receptors Abandoned AU2001297015A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24062800P 2000-10-16 2000-10-16
US60/240,628 2000-10-16
PCT/US2001/042602 WO2002033411A1 (en) 2000-10-16 2001-10-11 Improved ligand binding assays for vanilloid receptors

Publications (1)

Publication Number Publication Date
AU2001297015A1 true AU2001297015A1 (en) 2002-04-29

Family

ID=22907284

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001297015A Abandoned AU2001297015A1 (en) 2000-10-15 2001-10-11 Improved ligand binding assays for vanilloid receptors

Country Status (6)

Country Link
US (2) US6780650B2 (de)
EP (1) EP1328809A1 (de)
JP (1) JP2004511803A (de)
AU (1) AU2001297015A1 (de)
CA (1) CA2425961A1 (de)
WO (1) WO2002033411A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003241453A1 (en) 2002-05-17 2003-12-02 Janssen Pharmaceutica N.V. Aminotetralin-derived urea modulators of vanilloid vr1 receptor
WO2004069792A2 (en) 2003-02-03 2004-08-19 Janssen Pharmaceutica N.V. Quinoline-derived amide modulators of vanilloid vr1 receptor
WO2006069451A1 (de) * 2004-12-28 2006-07-06 Mestex Ag Verwendung von resiniferatoxin (rtx) für die herstellung eines mittels zur behandlung von gelenkschmerzen und verfahren zur applikation dieses mittels
WO2008057300A2 (en) * 2006-10-27 2008-05-15 Redpoint Bio Corporation Trpvi antagonists and uses thereof
CA3056665A1 (en) 2012-11-15 2014-05-22 Trevor Pearson Electrolytic generation of manganese (iii) ions in strong sulfuric acid
GB201310544D0 (en) * 2013-06-13 2013-07-31 Ucb Pharma Sa Obtaining an improved therapeutic ligand
US20170088971A1 (en) 2015-09-30 2017-03-30 Macdermid Acumen, Inc. Treatment of Etch Baths

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009140A1 (en) 1997-08-20 1999-02-25 The Regents Of The University Of California Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
JP2002531069A (ja) * 1998-11-13 2002-09-24 ミレニアム・フアーマシユーチカルズ・インコーポレーテツド タンパク質のカプサイシン／バニロイド受容体ファミリーの新規メンバー及びそれらの使用

Also Published As

Publication number Publication date
US6780650B2 (en) 2004-08-24
JP2004511803A (ja) 2004-04-15
WO2002033411A1 (en) 2002-04-25
EP1328809A1 (de) 2003-07-23
US20050019958A1 (en) 2005-01-27
US20020115105A1 (en) 2002-08-22
CA2425961A1 (en) 2002-04-25
WO2002033411A8 (en) 2002-08-01

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted