AU2001291260A1 - Topical aminolevulinic acid-photodynamic therapy for acne vulgaris - Google Patents
Topical aminolevulinic acid-photodynamic therapy for acne vulgarisInfo
- Publication number
- AU2001291260A1 AU2001291260A1 AU2001291260A AU9126001A AU2001291260A1 AU 2001291260 A1 AU2001291260 A1 AU 2001291260A1 AU 2001291260 A AU2001291260 A AU 2001291260A AU 9126001 A AU9126001 A AU 9126001A AU 2001291260 A1 AU2001291260 A1 AU 2001291260A1
- Authority
- AU
- Australia
- Prior art keywords
- photodynamic therapy
- aminolevulinic acid
- sebaceous gland
- acne vulgaris
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
Abstract
Light treatments of sebaceous gland disorders with 5-aminolevulinic acid and photodynamic therapy are disclosed. A preferred treatment includes topical application of 5-aminolevulinic acid to the skin followed by light exposures with repeated treatment at various intervals. At low doses of ALA and photodynamic therapy (PDT) in single or multiple treatments, improvement in the sebaceous gland disorder, e.g., acne, provides the discovery that diminishment in sebum secretion and the eradication of bacteria occurs. At high doses of ALA and a single high energy PDT treatment, permanent changes to the sebaceous gland and sebum secretion have been discovered.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22569100P | 2000-08-16 | 2000-08-16 | |
US60225691 | 2000-08-16 | ||
PCT/US2001/041691 WO2002013788A1 (en) | 2000-08-16 | 2001-08-13 | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001291260A1 true AU2001291260A1 (en) | 2002-02-25 |
Family
ID=22845856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001291260A Abandoned AU2001291260A1 (en) | 2000-08-16 | 2001-08-13 | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
Country Status (8)
Country | Link |
---|---|
US (4) | US6897238B2 (en) |
EP (2) | EP1313448B1 (en) |
JP (1) | JP2004506005A (en) |
AT (1) | ATE463237T1 (en) |
AU (1) | AU2001291260A1 (en) |
CA (1) | CA2422865C (en) |
DE (1) | DE60141758D1 (en) |
WO (1) | WO2002013788A1 (en) |
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-
2001
- 2001-08-13 AT AT01971365T patent/ATE463237T1/en not_active IP Right Cessation
- 2001-08-13 EP EP01971365A patent/EP1313448B1/en not_active Expired - Lifetime
- 2001-08-13 WO PCT/US2001/041691 patent/WO2002013788A1/en active Application Filing
- 2001-08-13 JP JP2002518935A patent/JP2004506005A/en active Pending
- 2001-08-13 EP EP10180457A patent/EP2269645A3/en not_active Withdrawn
- 2001-08-13 DE DE60141758T patent/DE60141758D1/en not_active Expired - Lifetime
- 2001-08-13 CA CA2422865A patent/CA2422865C/en not_active Expired - Fee Related
- 2001-08-13 AU AU2001291260A patent/AU2001291260A1/en not_active Abandoned
- 2001-08-14 US US09/929,384 patent/US6897238B2/en not_active Expired - Lifetime
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2004
- 2004-10-20 US US10/970,922 patent/US20050143466A1/en not_active Abandoned
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2009
- 2009-08-05 US US12/535,937 patent/US20090299268A1/en not_active Abandoned
-
2012
- 2012-08-03 US US13/566,442 patent/US20120296263A1/en not_active Abandoned
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ATE463237T1 (en) | 2010-04-15 |
WO2002013788A1 (en) | 2002-02-21 |
US20120296263A1 (en) | 2012-11-22 |
DE60141758D1 (en) | 2010-05-20 |
EP2269645A2 (en) | 2011-01-05 |
EP2269645A3 (en) | 2011-01-12 |
JP2004506005A (en) | 2004-02-26 |
EP1313448A1 (en) | 2003-05-28 |
US6897238B2 (en) | 2005-05-24 |
US20020099094A1 (en) | 2002-07-25 |
EP1313448A4 (en) | 2005-01-26 |
CA2422865C (en) | 2012-10-16 |
CA2422865A1 (en) | 2002-02-21 |
US20090299268A1 (en) | 2009-12-03 |
US20050143466A1 (en) | 2005-06-30 |
EP1313448B1 (en) | 2010-04-07 |
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