AU2001289844A1 - Amifostine-monohydrate and a method for the production thereof - Google Patents

Amifostine-monohydrate and a method for the production thereof

Info

Publication number
AU2001289844A1
AU2001289844A1 AU2001289844A AU8984401A AU2001289844A1 AU 2001289844 A1 AU2001289844 A1 AU 2001289844A1 AU 2001289844 A AU2001289844 A AU 2001289844A AU 8984401 A AU8984401 A AU 8984401A AU 2001289844 A1 AU2001289844 A1 AU 2001289844A1
Authority
AU
Australia
Prior art keywords
amifostine
monohydrate
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001289844A
Inventor
Martin Auer
Elisabeth Gstrein
Arnim Laicher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Publication of AU2001289844A1 publication Critical patent/AU2001289844A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
AU2001289844A 2000-09-01 2001-08-28 Amifostine-monohydrate and a method for the production thereof Abandoned AU2001289844A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2000143170 DE10043170C2 (en) 2000-09-01 2000-09-01 Amifostine monohydrate and process for its preparation
DE10043170 2000-09-01
PCT/EP2001/009902 WO2002018396A1 (en) 2000-09-01 2001-08-28 Amifostine-monohydrate and a method for the production thereof

Publications (1)

Publication Number Publication Date
AU2001289844A1 true AU2001289844A1 (en) 2002-03-13

Family

ID=7654684

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001289844A Abandoned AU2001289844A1 (en) 2000-09-01 2001-08-28 Amifostine-monohydrate and a method for the production thereof

Country Status (4)

Country Link
EP (1) EP1313745A1 (en)
AU (1) AU2001289844A1 (en)
DE (1) DE10043170C2 (en)
WO (1) WO2002018396A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006308660A1 (en) * 2005-11-03 2007-05-10 Albemarle Corporation Process for the preparation of (omega -aminoalkylamino)alkyl halides and conversion to amifostine
WO2007096901A1 (en) * 2006-02-24 2007-08-30 Natco Pharma Limited Novel dihydrate form of amifostine and process for its preparation
US8815833B2 (en) 2006-11-09 2014-08-26 Seidose, LLC Stable amifostine liquid concentrate
CN102286020A (en) * 2011-07-11 2011-12-21 大连美罗大药厂 Method for preparing 3-aminopropyl amine ethyl thiophosphoric acid monohydrate
CN103509049B (en) * 2013-10-15 2016-05-25 美罗药业股份有限公司 A kind of method of preparing medicinal Amifostine
EP3824880A1 (en) * 2019-11-25 2021-05-26 Clevexel Pharma Freeze-dried powder containing 2-[(3-aminopropyl)amino]ethanethiol and its use for preparing a thermogel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892824A (en) * 1968-12-16 1975-07-01 Southern Res Inst S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates
DD289448A7 (en) * 1982-07-29 1991-05-02 Amt Fuer Atomsicherheit Und Strahlenschutz,De PROCESS FOR THE PREPARATION OF S- [2- (3-AMINO-PROPYLAMINO) ETHYL] -DIHYDROGENTHIOPHOSPHATE
DD289449A7 (en) * 1983-07-29 1991-05-02 Amt Fuer Atomsicherheit Und Strahlenschutz,De PROCESS FOR THE PREPARATION OF S- [2- (3-AMINO-PROPYLAMINO) ETHYL] -DIHYDROGENTHIOPHOSPHATE
US5424471A (en) * 1992-07-31 1995-06-13 U.S. Bioscience, Inc. Crystalline amifostine compositions and methods of the preparation and use of same
SG47101A1 (en) * 1992-07-31 1998-03-20 Us Bioscience Crystalline amifostine compositions and methods for the preparation and use of same
US6407278B2 (en) * 1998-11-16 2002-06-18 Medimmune Oncology, Inc. Stable amorphous amifostine compositions and methods for the preparation and use of the same

Also Published As

Publication number Publication date
WO2002018396A1 (en) 2002-03-07
DE10043170C2 (en) 2002-10-24
DE10043170A1 (en) 2002-03-28
EP1313745A1 (en) 2003-05-28

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