AU2001289708A1 - Method for producing a crystalline tableting additive, additive thus obtained and use thereof - Google Patents

Method for producing a crystalline tableting additive, additive thus obtained and use thereof

Info

Publication number
AU2001289708A1
AU2001289708A1 AU2001289708A AU8970801A AU2001289708A1 AU 2001289708 A1 AU2001289708 A1 AU 2001289708A1 AU 2001289708 A AU2001289708 A AU 2001289708A AU 8970801 A AU8970801 A AU 8970801A AU 2001289708 A1 AU2001289708 A1 AU 2001289708A1
Authority
AU
Australia
Prior art keywords
additive
tableting
producing
crystalline
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001289708A
Inventor
Klaas Daniel Kussendrager
Henricus Alphonsus Maria Van Den Biggelaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Campina Melkune BV
Original Assignee
Campina Melkune BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Campina Melkune BV filed Critical Campina Melkune BV
Publication of AU2001289708A1 publication Critical patent/AU2001289708A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B30/00—Crystallisation; Crystallising apparatus; Separating crystals from mother liquors ; Evaporating or boiling sugar juice
    • C13B30/02—Crystallisation; Crystallising apparatus
    • C13B30/028—Crystallisation; Crystallising apparatus obtaining sugar crystals by drying sugar syrup or sugar juice, e.g. spray-crystallisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K5/00—Lactose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Abstract

A method for producing a tableting additive, which method comprises providing a spray dried tableting additive in particulate form which particles at leas partially consist of amorphous additive material and at least partially of crystalline additive material; and crystallising the amorphous additive material by subjecting the particles for a short time and under agitation to a temperature between 30 and 100° C. at a relative humidity between 60 and 25%. More in particular, the relationship between relative humidity and temperature is defined by the formula: % relative humidity=218-47*Ln(T(° C.)), wherein T(° C.) is the temperature to which the particles are subjected.
AU2001289708A 2000-07-20 2001-07-19 Method for producing a crystalline tableting additive, additive thus obtained and use thereof Abandoned AU2001289708A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL1015752 2000-07-20
NL1015752 2000-07-20
PCT/EP2001/008394 WO2002008470A1 (en) 2000-07-20 2001-07-19 Method for producing a crystalline tableting additive, additive thus obtained and use thereof

Publications (1)

Publication Number Publication Date
AU2001289708A1 true AU2001289708A1 (en) 2002-02-05

Family

ID=19771767

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001289708A Abandoned AU2001289708A1 (en) 2000-07-20 2001-07-19 Method for producing a crystalline tableting additive, additive thus obtained and use thereof

Country Status (9)

Country Link
US (2) US20040014714A1 (en)
EP (1) EP1301638B1 (en)
JP (1) JP5033297B2 (en)
AT (1) ATE374261T1 (en)
AU (1) AU2001289708A1 (en)
DE (1) DE60130657T2 (en)
HK (1) HK1057066A1 (en)
NZ (1) NZ523198A (en)
WO (1) WO2002008470A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002008470A1 (en) 2000-07-20 2002-01-31 Campina B.V. Method for producing a crystalline tableting additive, additive thus obtained and use thereof
WO2006068484A2 (en) * 2004-12-22 2006-06-29 Campina Nederland Holding B.V. Anhdyrous lactose agglomerates and the preparation thereof
MY181647A (en) 2014-09-09 2020-12-30 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
US10820608B1 (en) 2015-10-26 2020-11-03 The Hershey Company Hard candy confections with low hygroscopicity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3085914A (en) * 1959-06-30 1963-04-16 Corn Products Co Novel crystalline sugar products
JPS5519237A (en) * 1978-07-27 1980-02-09 Toa Iyakuhin Kogyo Kk Crystalline lactose with high beta-lactose content and diluent comprising it
NL8301220A (en) * 1983-04-07 1984-11-01 Dmv Campina Bv PROCESS FOR PREPARING LACTOSE PRODUCTS.
NL8600731A (en) 1986-03-21 1987-10-16 Dmv Campina Bv Improved spray-dried lactose and process for its preparation.
IE67345B1 (en) * 1991-03-12 1996-03-20 Akzo Nv Low dose dry pharmaceutical preparations
NL9100691A (en) * 1991-04-19 1992-11-16 Dmv Campina Bv TABLETING AUXILIARY.
US5597416A (en) * 1993-10-07 1997-01-28 Fuisz Technologies Ltd. Method of making crystalline sugar and products resulting therefrom
PL207953B1 (en) * 1998-03-16 2011-02-28 Astellas Pharma Inc Tablets quickly disintegrating in the oral cavity and process for producing the same
WO2002008470A1 (en) 2000-07-20 2002-01-31 Campina B.V. Method for producing a crystalline tableting additive, additive thus obtained and use thereof

Also Published As

Publication number Publication date
DE60130657D1 (en) 2007-11-08
EP1301638A1 (en) 2003-04-16
HK1057066A1 (en) 2004-03-12
JP2004504367A (en) 2004-02-12
US20040014714A1 (en) 2004-01-22
NZ523198A (en) 2004-11-26
JP5033297B2 (en) 2012-09-26
DE60130657T2 (en) 2008-07-03
US20120220764A1 (en) 2012-08-30
ATE374261T1 (en) 2007-10-15
EP1301638B1 (en) 2007-09-26
WO2002008470A1 (en) 2002-01-31
US8501236B2 (en) 2013-08-06

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