AU2001289619B2 - Thiophene retinoids - Google Patents

Thiophene retinoids Download PDF

Info

Publication number
AU2001289619B2
AU2001289619B2 AU2001289619A AU2001289619A AU2001289619B2 AU 2001289619 B2 AU2001289619 B2 AU 2001289619B2 AU 2001289619 A AU2001289619 A AU 2001289619A AU 2001289619 A AU2001289619 A AU 2001289619A AU 2001289619 B2 AU2001289619 B2 AU 2001289619B2
Authority
AU
Australia
Prior art keywords
compounds
formula
tetramethyl
hydrogen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001289619A
Other languages
English (en)
Other versions
AU2001289619A1 (en
Inventor
Michael Klaus
Jean-Marc Lapierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2001289619A1 publication Critical patent/AU2001289619A1/en
Application granted granted Critical
Publication of AU2001289619B2 publication Critical patent/AU2001289619B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AU2001289619A 2000-07-10 2001-06-30 Thiophene retinoids Ceased AU2001289619B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00114767 2000-07-10
EP00114767.7 2000-07-10
PCT/EP2001/007506 WO2002004439A2 (en) 2000-07-10 2001-06-30 Thiophene retinoids

Publications (2)

Publication Number Publication Date
AU2001289619A1 AU2001289619A1 (en) 2002-04-18
AU2001289619B2 true AU2001289619B2 (en) 2006-07-13

Family

ID=8169205

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001289619A Ceased AU2001289619B2 (en) 2000-07-10 2001-06-30 Thiophene retinoids
AU8961901A Pending AU8961901A (en) 2000-07-10 2001-06-30 Thiophene retinoids

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU8961901A Pending AU8961901A (en) 2000-07-10 2001-06-30 Thiophene retinoids

Country Status (12)

Country Link
US (1) US6403810B2 (https=)
EP (1) EP1301505A2 (https=)
JP (1) JP2004502767A (https=)
KR (1) KR100551778B1 (https=)
CN (1) CN1219777C (https=)
AR (1) AR029572A1 (https=)
AU (2) AU2001289619B2 (https=)
BR (1) BR0112328A (https=)
CA (1) CA2414936C (https=)
MX (1) MXPA03000222A (https=)
WO (1) WO2002004439A2 (https=)
ZA (1) ZA200210049B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
EP1723142A1 (en) * 2004-03-11 2006-11-22 Theravance, Inc. Diphenylmethyl compounds useful as muscarinic receptor antagonists
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
US7781187B2 (en) * 2005-12-30 2010-08-24 Corning Incorporated Fluorescent dyes
WO2008063842A2 (en) * 2006-11-02 2008-05-29 Aestus Therapeutics, Inc. Methods of treating neuropathic pain with agonists of ppar-gamma
WO2025109225A1 (en) 2023-11-24 2025-05-30 Etherna Immunotherapies Nv Method for reducing dsrna formation during ivt

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025530A2 (en) * 1992-06-11 1993-12-23 Allergan, Inc. Vinyl arenas having retinoid-like activity
WO1994020093A1 (en) * 1993-03-11 1994-09-15 Allergan, Inc. Treatment of tumors with compounds having rxr retinoid receptor agonist activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123469A (en) 1977-06-30 1978-10-31 International Flavors & Fragrances Inc. Process for production of bicyclic compounds
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US5475022A (en) * 1993-10-18 1995-12-12 Allergan, Inc. Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity
FR2743560B1 (fr) * 1996-01-17 1998-04-03 Europ De Bioprospective Centre Derives polycycliques aromatiques de type retinoide, leur procede de preparation et leur utilisation pour la fabrication de compositions pharmaceutiques et cosmetiques
FR2753091B1 (fr) * 1996-09-09 2001-03-16 Oreal Utilisation d'un agoniste des recepteurs des retinoides de type rxr pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025530A2 (en) * 1992-06-11 1993-12-23 Allergan, Inc. Vinyl arenas having retinoid-like activity
WO1994020093A1 (en) * 1993-03-11 1994-09-15 Allergan, Inc. Treatment of tumors with compounds having rxr retinoid receptor agonist activity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemico-Biological Interactions 100 (1996) pp1-12 *

Also Published As

Publication number Publication date
WO2002004439A3 (en) 2002-09-26
BR0112328A (pt) 2003-07-22
KR20030040350A (ko) 2003-05-22
CA2414936A1 (en) 2002-01-17
WO2002004439A2 (en) 2002-01-17
US20020019438A1 (en) 2002-02-14
KR100551778B1 (ko) 2006-02-13
CA2414936C (en) 2006-12-05
EP1301505A2 (en) 2003-04-16
JP2004502767A (ja) 2004-01-29
CN1219777C (zh) 2005-09-21
AR029572A1 (es) 2003-07-02
ZA200210049B (en) 2004-03-11
US6403810B2 (en) 2002-06-11
MXPA03000222A (es) 2003-06-06
AU8961901A (en) 2002-01-21
CN1441798A (zh) 2003-09-10

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired