AU2001285157A1 - 5t4 rna in plasma and serum as a marker for neoplastic disease - Google Patents

5t4 rna in plasma and serum as a marker for neoplastic disease

Info

Publication number
AU2001285157A1
AU2001285157A1 AU2001285157A AU8515701A AU2001285157A1 AU 2001285157 A1 AU2001285157 A1 AU 2001285157A1 AU 2001285157 A AU2001285157 A AU 2001285157A AU 8515701 A AU8515701 A AU 8515701A AU 2001285157 A1 AU2001285157 A1 AU 2001285157A1
Authority
AU
Australia
Prior art keywords
rna
serum
plasma
neoplastic disease
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001285157A
Inventor
Christopher D. Gocke
Michael S. Kopreski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OncoMEDx Inc
Original Assignee
OncoMEDx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/649,371 external-priority patent/US6794135B1/en
Application filed by OncoMEDx Inc filed Critical OncoMEDx Inc
Publication of AU2001285157A1 publication Critical patent/AU2001285157A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Abstract

This invention relates to methods of detecting or inferring the presence of malignant or premalignant cells in a human that express 5T4. Provided are methods for detecting 5T4 RNA in blood, plasma, serum, other bodily fluids, cells, and tissues. The invention thereby provides an aid for the detection, diagnosis, monitoring, treatment, or evaluation of neoplastic disease.
AU2001285157A 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease Abandoned AU2001285157A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/649,371 US6794135B1 (en) 1996-03-26 2000-08-28 Method for detection of 5T4 RNA in plasma or serum
US09/649,371 2000-08-28
PCT/US2001/026119 WO2002018645A2 (en) 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease

Publications (1)

Publication Number Publication Date
AU2001285157A1 true AU2001285157A1 (en) 2002-03-13

Family

ID=24604503

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001285157A Abandoned AU2001285157A1 (en) 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease

Country Status (6)

Country Link
US (2) US20050260594A1 (en)
EP (1) EP1354060B1 (en)
AT (1) ATE498020T1 (en)
AU (1) AU2001285157A1 (en)
DE (1) DE60144027D1 (en)
WO (1) WO2002018645A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2498783A1 (en) * 2002-09-12 2004-03-25 Yissum Research Development Company Of The Hebrew University Of Jerusale M Method for detection of micro-metastasis
US8252529B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
US8614057B2 (en) * 2008-06-12 2013-12-24 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
US8252528B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods, compositions, and kits for collecting and detecting oligonucleotides
GB0822836D0 (en) * 2008-12-15 2009-01-21 Oxford Biomedica Ltd Method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869053A (en) * 1988-03-04 1999-02-09 Cancer Research Campaign Technology, Ltd. 5T4 antigen from human trophoblasts
EP0403559A1 (en) * 1988-03-04 1990-12-27 Cancer Research Campaign Technology Limited Improvements relating to antigens
AU675774B2 (en) * 1991-10-04 1997-02-20 Children's Hospital Of Philadelphia, The Detecting digeorge syndrome mutations
CA2250118C (en) * 1996-03-26 2009-09-29 Michael S. Kopreski Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer
US5939262A (en) * 1996-07-03 1999-08-17 Ambion, Inc. Ribonuclease resistant RNA preparation and utilization
GB9704444D0 (en) * 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US6664056B2 (en) * 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring
FR2839015A1 (en) * 2002-04-29 2003-10-31 Conception & Dev Michelin Sa Flexible non-pneumatic tire comprising a series of articulated joints between supporting elements and interconnecting structure
CA2513292C (en) * 2003-01-17 2016-04-05 The Chinese University Of Hong Kong Circulating mrna as diagnostic markers for pregnancy-related disorders

Also Published As

Publication number Publication date
WO2002018645A2 (en) 2002-03-07
ATE498020T1 (en) 2011-02-15
WO2002018645A3 (en) 2003-07-24
DE60144027D1 (en) 2011-03-24
US20050260594A1 (en) 2005-11-24
EP1354060A2 (en) 2003-10-22
EP1354060B1 (en) 2011-02-09
US20080200410A1 (en) 2008-08-21

Similar Documents

Publication Publication Date Title
WO2002018652A3 (en) Method for detection of htr and htert telomerase-associated rna in plasma or serum
WO2003028531A3 (en) Detection of tumor rna in plasma and serum
AU2002327308A1 (en) Methods for evaluating pathologic conditions using extracellular rna
WO2002054081A3 (en) Proteins, genes and their use for diagnosis and treatment of kidney response
AU2867302A (en) Fluorescence-mediated molecular tomography
WO2002040634A3 (en) Expression miniarrays and uses thereof
WO2002031507A3 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2002018651A3 (en) Methods for detecting papillomavirus dna in blood plasma and serum
WO2002059604A8 (en) Diagnosis and treatment of multiple sclerosis
AU2002246668A1 (en) Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (sclc)
WO1998045328A3 (en) Compositions and methods for the treatment and diagnosis of breast cancer
NZ338068A (en) Diagnosis of early gastric cancer detecting cyclooxygenase-2 mRNA expression or Cox-2 protein overexpression
WO2003001183A3 (en) Methods for detecting and monitoring cox-2 rna in plasma and serum
WO2004031414A3 (en) Method for diagnosing prostate cancer
AU2001240909A1 (en) Proteins, genes and their use for diagnosis and treatment of breast cancer
WO2001062784A3 (en) Use of breast cancer associated membrane proteins (bcmp) for treatment, prophylaxis and diagnosis of breast cancer
AU6630101A (en) Chest piece for stethoscopes, and methods of utilizing stethoscopes for monitoring the physiological conditons of patient
AU6583700A (en) Proteins, genes and their use for diagnosis and treatment of breast cancer
AU6425800A (en) Agents for the diagnosis, prognosis and treatment of malignant diseases
AU2001285157A1 (en) 5t4 rna in plasma and serum as a marker for neoplastic disease
WO2003048734A3 (en) Detection of matrix metalloproteinase rna in plasma and serum
AU2001243349A1 (en) Methods for the diagnosis and treatment of breast cancer
WO2000061753A3 (en) Compositions and methods for the treatment and diagnosis of breast cancer
WO2001062785A3 (en) Protein and gene and their use for diagnosis and treatment of schizophrenia
AU2842901A (en) Use of contrast agents in the manufacture of diagnostic agent for the visualisation of the intestinal lumen