WO2000061753A3 - Compositions and methods for the treatment and diagnosis of breast cancer - Google Patents

Compositions and methods for the treatment and diagnosis of breast cancer Download PDF

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Publication number
WO2000061753A3
WO2000061753A3 PCT/US2000/009312 US0009312W WO0061753A3 WO 2000061753 A3 WO2000061753 A3 WO 2000061753A3 US 0009312 W US0009312 W US 0009312W WO 0061753 A3 WO0061753 A3 WO 0061753A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast cancer
compositions
treatment
methods
diagnosis
Prior art date
Application number
PCT/US2000/009312
Other languages
French (fr)
Other versions
WO2000061753A2 (en
Inventor
Tony N Frudakis
John M Smith
Steven G Reed
Lynda E Misher
Marc W Retter
Davin C Dillon
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/289,198 external-priority patent/US6586570B1/en
Priority claimed from US09/429,755 external-priority patent/US6656480B2/en
Priority claimed from US09/534,825 external-priority patent/US6861506B1/en
Priority to CA002365909A priority Critical patent/CA2365909A1/en
Priority to IL14571900A priority patent/IL145719A0/en
Priority to JP2000611676A priority patent/JP2002541803A/en
Priority to MXPA01010186A priority patent/MXPA01010186A/en
Priority to NZ514646A priority patent/NZ514646A/en
Application filed by Corixa Corp filed Critical Corixa Corp
Priority to AU42130/00A priority patent/AU774824B2/en
Priority to BR0009573-7A priority patent/BR0009573A/en
Priority to EP00921869A priority patent/EP1169444A2/en
Priority to KR1020017012887A priority patent/KR20020026418A/en
Publication of WO2000061753A2 publication Critical patent/WO2000061753A2/en
Publication of WO2000061753A3 publication Critical patent/WO2000061753A3/en
Priority to NO20014805A priority patent/NO20014805L/en
Priority to AU2004218695A priority patent/AU2004218695B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Compositions and methods for the detection and therapy of breast cancer are disclosed. The compounds provided include nucleotide sequences that are preferentially expressed in breast tumor tissue, as well as polypeptides encoded by such nucleotide sequences. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for the prevention and treatment of breast cancer. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring the progression of breast cancer in a patient.
PCT/US2000/009312 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer WO2000061753A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
BR0009573-7A BR0009573A (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
EP00921869A EP1169444A2 (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
IL14571900A IL145719A0 (en) 1999-04-09 2000-04-07 Polypeptides encoded by nucleotide sequences expressed in breast tumor tissue and uses thereof
KR1020017012887A KR20020026418A (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
JP2000611676A JP2002541803A (en) 1999-04-09 2000-04-07 Compositions and methods for treatment and diagnosis of breast cancer
MXPA01010186A MXPA01010186A (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer.
NZ514646A NZ514646A (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
CA002365909A CA2365909A1 (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
AU42130/00A AU774824B2 (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer
NO20014805A NO20014805L (en) 1999-04-09 2001-10-03 Mixtures and Methods for Treating and Diagnosing Breast Cancer
AU2004218695A AU2004218695B2 (en) 1999-04-09 2004-10-08 Compositions and methods for the treatment and diagnosis of breast cancer

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US09/289,198 US6586570B1 (en) 1996-01-11 1999-04-09 Compositions and methods for the treatment and diagnosis of breast cancer
US09/289,198 1999-04-09
US09/429,755 US6656480B2 (en) 1996-01-11 1999-10-28 Compositions and methods for the treatment and diagnosis of breast cancer
US09/429,755 1999-10-28
US09/534,825 2000-03-23
US09/534,825 US6861506B1 (en) 1996-01-11 2000-03-23 Compositions and methods for the treatment and diagnosis of breast cancer

Publications (2)

Publication Number Publication Date
WO2000061753A2 WO2000061753A2 (en) 2000-10-19
WO2000061753A3 true WO2000061753A3 (en) 2001-06-28

Family

ID=27403868

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/009312 WO2000061753A2 (en) 1999-04-09 2000-04-07 Compositions and methods for the treatment and diagnosis of breast cancer

Country Status (15)

Country Link
EP (1) EP1169444A2 (en)
JP (1) JP2002541803A (en)
KR (1) KR20020026418A (en)
CN (1) CN1352683A (en)
AU (1) AU774824B2 (en)
BR (1) BR0009573A (en)
CA (1) CA2365909A1 (en)
CZ (1) CZ20013575A3 (en)
HU (1) HUP0200825A2 (en)
IL (1) IL145719A0 (en)
MX (1) MXPA01010186A (en)
NO (1) NO20014805L (en)
NZ (1) NZ514646A (en)
PL (1) PL350863A1 (en)
WO (1) WO2000061753A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030125536A1 (en) * 1996-01-11 2003-07-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US7241876B2 (en) 1996-01-11 2007-07-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6656480B2 (en) 1996-01-11 2003-12-02 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
US6586570B1 (en) 1996-01-11 2003-07-01 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
US6861506B1 (en) 1996-01-11 2005-03-01 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
US6828431B1 (en) 1999-04-09 2004-12-07 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US20020068285A1 (en) * 1996-01-11 2002-06-06 Frudakis Tony N. Compositions and methods for the therapy and diagnosis of breast cancer
US20040081653A1 (en) 2002-08-16 2004-04-29 Raitano Arthur B. Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
CN111983220B (en) * 2019-05-21 2024-03-19 北京中科纳泰生物科技有限公司 Polypeptide magnetic nanoparticle, preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997025431A1 (en) * 1996-01-10 1997-07-17 Corixa Corporation Compositions and methods for the treatment and diagnosis of cancer
WO1997025426A2 (en) * 1996-01-11 1997-07-17 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
WO1998045328A2 (en) * 1997-04-09 1998-10-15 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE440951T1 (en) * 1997-12-17 2009-09-15 Serono Genetics Inst Sa EXTENDED CDNS CODING SECRETED PROTEINS
CN100419079C (en) * 1998-07-14 2008-09-17 科里克萨有限公司 Compositions and methods for therapy and diagnosis of prostate cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997025431A1 (en) * 1996-01-10 1997-07-17 Corixa Corporation Compositions and methods for the treatment and diagnosis of cancer
WO1997025426A2 (en) * 1996-01-11 1997-07-17 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
WO1998045328A2 (en) * 1997-04-09 1998-10-15 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer

Also Published As

Publication number Publication date
KR20020026418A (en) 2002-04-10
BR0009573A (en) 2002-04-16
PL350863A1 (en) 2003-02-10
MXPA01010186A (en) 2004-08-12
JP2002541803A (en) 2002-12-10
WO2000061753A2 (en) 2000-10-19
CN1352683A (en) 2002-06-05
EP1169444A2 (en) 2002-01-09
NZ514646A (en) 2005-04-29
IL145719A0 (en) 2002-07-25
AU4213000A (en) 2000-11-14
HUP0200825A2 (en) 2002-07-29
NO20014805D0 (en) 2001-10-03
NO20014805L (en) 2001-12-06
CA2365909A1 (en) 2000-10-19
CZ20013575A3 (en) 2002-10-16
AU774824B2 (en) 2004-07-08

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