AU2001284741A1 - Method for purification of acarbose - Google Patents
Method for purification of acarboseInfo
- Publication number
- AU2001284741A1 AU2001284741A1 AU2001284741A AU8474101A AU2001284741A1 AU 2001284741 A1 AU2001284741 A1 AU 2001284741A1 AU 2001284741 A AU2001284741 A AU 2001284741A AU 8474101 A AU8474101 A AU 8474101A AU 2001284741 A1 AU2001284741 A1 AU 2001284741A1
- Authority
- AU
- Australia
- Prior art keywords
- acarbose
- purification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- XUFXOAAUWZOOIT-SXARVLRPSA-N (2R,3R,4R,5S,6R)-5-[[(2R,3R,4R,5S,6R)-5-[[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohex-2-enyl]amino]-2-oxanyl]oxy]-3,4-dihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6-(hydroxymethyl)oxane-2,3,4-triol Chemical compound O([C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@@H]([C@H]([C@H](O)[C@H]1O)N[C@@H]1[C@@H]([C@@H](O)[C@H](O)C(CO)=C1)O)C)[C@@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O XUFXOAAUWZOOIT-SXARVLRPSA-N 0.000 title 1
- 229960002632 acarbose Drugs 0.000 title 1
- XUFXOAAUWZOOIT-UHFFFAOYSA-N acarviostatin I01 Natural products OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC1C(CO)OC(O)C(O)C1O XUFXOAAUWZOOIT-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
- C07H1/08—Separation; Purification from natural products
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22349200P | 2000-08-07 | 2000-08-07 | |
| US60223492 | 2000-08-07 | ||
| PCT/US2001/024729 WO2002012256A1 (en) | 2000-08-07 | 2001-08-07 | Method for purification of acarbose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001284741A1 true AU2001284741A1 (en) | 2002-02-18 |
Family
ID=22836739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001284741A Abandoned AU2001284741A1 (en) | 2000-08-07 | 2001-08-07 | Method for purification of acarbose |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1309601A1 (en) |
| AU (1) | AU2001284741A1 (en) |
| WO (1) | WO2002012256A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20010792A2 (en) | 2001-10-26 | 2003-04-30 | Pliva D D | Acarbose purification process |
| CN102030786A (en) * | 2010-11-12 | 2011-04-27 | 丽珠集团新北江制药股份有限公司 | Preparation method of acarbose |
| CN104693250B (en) * | 2015-03-06 | 2017-04-19 | 成都大学 | Method for purifying acarbose from acarbose-containing solution |
| CN106397506B (en) * | 2016-08-31 | 2019-06-11 | 杭州中美华东制药有限公司 | A kind of purification process of high-quality acarbose |
| CN108148104A (en) * | 2017-12-25 | 2018-06-12 | 苏州纳微科技有限公司 | A kind of isolation and purification method of acarbose |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2719912C3 (en) * | 1977-05-04 | 1979-12-06 | Bayer Ag, 5090 Leverkusen | Process for the isolation of 0- | 4,6-dideoxy-4- [JJl SO, 4,6 / 5) -4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a - D-glucopyranosyl} - (I right arrow 4) -0- a D-glucopyranosyl- (l right arrow 4) -D-glucopyranose from culture broths |
| DE3439008A1 (en) * | 1984-10-25 | 1986-04-30 | Bayer Ag, 5090 Leverkusen | POLYMERISATES FOR CLEANING ACARBOSE |
| DE3543999A1 (en) * | 1985-12-13 | 1987-06-19 | Bayer Ag | HIGH PURITY ACARBOSE |
-
2001
- 2001-08-07 WO PCT/US2001/024729 patent/WO2002012256A1/en not_active Application Discontinuation
- 2001-08-07 EP EP01963821A patent/EP1309601A1/en not_active Withdrawn
- 2001-08-07 AU AU2001284741A patent/AU2001284741A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002012256A1 (en) | 2002-02-14 |
| EP1309601A1 (en) | 2003-05-14 |
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