AU2001284247A1 - Bicyclic enamide derivatives being integrin inhibitors - Google Patents

Bicyclic enamide derivatives being integrin inhibitors

Info

Publication number
AU2001284247A1
AU2001284247A1 AU2001284247A AU8424701A AU2001284247A1 AU 2001284247 A1 AU2001284247 A1 AU 2001284247A1 AU 2001284247 A AU2001284247 A AU 2001284247A AU 8424701 A AU8424701 A AU 8424701A AU 2001284247 A1 AU2001284247 A1 AU 2001284247A1
Authority
AU
Australia
Prior art keywords
bicyclic
integrin inhibitors
enamide derivatives
enamide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284247A
Inventor
John Clifford Head
Timothy John Norman
John Robert Porter
Andrew James Ratcliffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of AU2001284247A1 publication Critical patent/AU2001284247A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001284247A 2000-09-06 2001-09-03 Bicyclic enamide derivatives being integrin inhibitors Abandoned AU2001284247A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0021898.2A GB0021898D0 (en) 2000-09-06 2000-09-06 Chemical compounds
GB0021898 2000-09-06
PCT/GB2001/003942 WO2002020522A1 (en) 2000-09-06 2001-09-03 Bicyclic enamide derivatives being integrin inhibitors

Publications (1)

Publication Number Publication Date
AU2001284247A1 true AU2001284247A1 (en) 2002-03-22

Family

ID=9898977

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284247A Abandoned AU2001284247A1 (en) 2000-09-06 2001-09-03 Bicyclic enamide derivatives being integrin inhibitors

Country Status (5)

Country Link
US (1) US6603041B2 (en)
EP (1) EP1315725A1 (en)
AU (1) AU2001284247A1 (en)
GB (1) GB0021898D0 (en)
WO (1) WO2002020522A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE375330T1 (en) * 2000-04-17 2007-10-15 Ucb Pharma Sa ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US6329372B1 (en) * 1998-01-27 2001-12-11 Celltech Therapeutics Limited Phenylalanine derivatives
GB9811159D0 (en) * 1998-05-22 1998-07-22 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) * 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9821406D0 (en) * 1998-10-01 1998-11-25 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) * 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
ATE375330T1 (en) * 2000-04-17 2007-10-15 Ucb Pharma Sa ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES

Also Published As

Publication number Publication date
US6603041B2 (en) 2003-08-05
EP1315725A1 (en) 2003-06-04
WO2002020522A1 (en) 2002-03-14
US20020072607A1 (en) 2002-06-13
GB0021898D0 (en) 2000-10-25

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