AU2001283354A1 - Compositions containing hypoglycemically active stilbenoids - Google Patents

Compositions containing hypoglycemically active stilbenoids

Info

Publication number
AU2001283354A1
AU2001283354A1 AU2001283354A AU8335401A AU2001283354A1 AU 2001283354 A1 AU2001283354 A1 AU 2001283354A1 AU 2001283354 A AU2001283354 A AU 2001283354A AU 8335401 A AU8335401 A AU 8335401A AU 2001283354 A1 AU2001283354 A1 AU 2001283354A1
Authority
AU
Australia
Prior art keywords
compositions containing
hypoglycemically active
stilbenoids
active stilbenoids
hypoglycemically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283354A
Inventor
David Craig Hoppe
Wayne D. Inman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insmed Inc
Original Assignee
Insmed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insmed Inc filed Critical Insmed Inc
Publication of AU2001283354A1 publication Critical patent/AU2001283354A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001283354A 2000-08-16 2001-08-15 Compositions containing hypoglycemically active stilbenoids Abandoned AU2001283354A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22566500P 2000-08-16 2000-08-16
US60/225,665 2000-08-16
US09/919,883 2001-08-02
US09/919,883 US6552085B2 (en) 2000-08-16 2001-08-02 Compositions containing hypoglycemically active stilbenoids
PCT/US2001/025382 WO2002014252A2 (en) 2000-08-16 2001-08-15 Compositions containing hypoglycemically active stilbenoids

Publications (1)

Publication Number Publication Date
AU2001283354A1 true AU2001283354A1 (en) 2002-02-25

Family

ID=26919818

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283354A Abandoned AU2001283354A1 (en) 2000-08-16 2001-08-15 Compositions containing hypoglycemically active stilbenoids

Country Status (3)

Country Link
US (1) US6552085B2 (en)
AU (1) AU2001283354A1 (en)
WO (1) WO2002014252A2 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7321050B2 (en) * 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
US6410596B1 (en) * 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US6541522B2 (en) 2000-08-16 2003-04-01 Insmed Incorporated Methods of using compositions containing hypotriglyceridemically active stilbenoids
US20020058708A1 (en) * 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
EP1435894A4 (en) * 2001-07-23 2005-07-06 Galileo Pharmaceuticals Inc Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
CN1398838A (en) 2001-07-26 2003-02-26 中国人民解放军军事医学科学院放射医学研究所 Diphenylethylene compound and its prepn and application in preventing and treating diabetes
WO2003039557A1 (en) * 2001-11-02 2003-05-15 The Regents Of The University Of California Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US20060025337A1 (en) * 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
WO2005002672A2 (en) * 2003-07-01 2005-01-13 President And Fellows Of Harvard College Sirt1 modulators for manipulating cells/organism lifespan/stress response
CA2548671C (en) 2003-12-29 2015-02-24 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) * 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
GB2411353A (en) * 2004-02-25 2005-08-31 Univ Hertfordshire Resveratrol Analogues
WO2006007411A2 (en) * 2004-06-16 2006-01-19 President And Fellows Of Harvard College Methods and compositions for modulating bax-mediated apoptosis
WO2006004722A2 (en) * 2004-06-30 2006-01-12 Biomol Research Laboratories, Inc. Compositions and methods for selectively activating human sirtuins
CA2595486A1 (en) * 2005-01-20 2006-07-27 Sirtris Pharmaceuticals, Inc. Use of sirtuin-activating compounds for treating flushing and drug induced weight gain
WO2006138418A2 (en) * 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
EP1984317A1 (en) * 2006-02-16 2008-10-29 DSMIP Assets B.V. Novel nutraceutical and pharmaceutical compositions and use thereof for the treatment, co-treatment or prevention of inflammatory disorders
KR100902338B1 (en) * 2007-07-26 2009-06-12 한국과학기술연구원 A composition that is comprising extracts, fractions or isolated single compounds of Robinia pseudo?acacia var. umbraculifera
US20100273203A1 (en) * 2009-04-23 2010-10-28 Board Of Trustees Of The University Of Arkansas Methods and compositions for detecting metabolites
US20100119499A1 (en) * 2009-09-17 2010-05-13 Kneller Bruce W Stilbene-based compositions and methods of use therefor
US8535739B2 (en) * 2010-01-28 2013-09-17 George Lowe Sparkle essence system
US8883218B2 (en) * 2010-03-26 2014-11-11 The Board Of Trustees Of The University Of Arkansas Anti-cancer nanoparticle compositions and methods of use
CN102372627B (en) * 2010-08-18 2015-05-27 中国医学科学院医药生物技术研究所 Preparation method of cajanin and substance with similar structure
US9044491B2 (en) * 2010-12-28 2015-06-02 The Board Of Trustees Of The University Of Arkansas Method for improving blood flow using stilbenoid derivatives
US9095598B2 (en) * 2010-12-28 2015-08-04 The Board Of Trustees Of The University Of Arkansas Stilbenoid derivatives and their uses
CA2826034A1 (en) 2011-01-28 2012-08-02 University Of Kentucky Research Foundation Stilbene analogs and methods of treating cancer
CN103172512B (en) * 2011-12-23 2016-08-03 中国医学科学院医药生物技术研究所 One group of cajanin structurally similar compounds, preparation method and application
KR101564485B1 (en) * 2013-02-15 2015-10-30 단국대학교 산학협력단 Novel use of pinosylvin in promoting angiogenesis
CN103483158B (en) * 2013-10-14 2016-06-08 武汉英纳氏药业有限公司 A kind of diphenyl ethane derivative and application thereof
CN106748666B (en) * 2016-12-01 2021-01-05 南昌大学 Natural medicine for reducing blood sugar and its use in preparing medicine for diabetes or obesity
CN106748664B (en) * 2016-12-01 2020-12-04 南昌大学 Novel bibenzyl natural medicine with blood sugar reducing effect and application thereof
CN106580933B (en) * 2016-12-01 2019-04-12 南昌大学 The purposes of 3,5- dihydroxy -2- [3,7- dimethyl -2 (trans-), 6- octadienyl]-bibenzyl
CN106748778B (en) * 2016-12-01 2019-12-20 南昌大学 New bibenzyl natural medicine with hypoglycemic effect and its prepn and use
WO2018206719A1 (en) * 2017-05-10 2018-11-15 Evolva Sa Compounds for upregulating ucp1 expression and promoting transdifferentiation into brown adipose tissue
MX2020004785A (en) 2017-11-10 2020-08-13 Dermavant Sciences GmbH Process for preparing tapinarof.
CN114028367A (en) * 2021-12-07 2022-02-11 广州精域生物科技有限公司 Application of cajanin derivative in preparation of medicine for preventing and/or treating novel coronavirus infection diseases
CN115120579B (en) * 2022-08-10 2023-10-03 中国科学院华南植物园 Application of cajan leaf extract and monomer components thereof in preparation of xanthine oxidase inhibition drugs

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE275959T1 (en) * 1992-05-19 2004-10-15 Graham Edmund Kelly USE OF ISOFLAVONE PHYTO-ESTROGEN EXTRACTS OF SOY OR CLOVER
US5827898A (en) 1996-10-07 1998-10-27 Shaman Pharmaceuticals, Inc. Use of bisphenolic compounds to treat type II diabetes
FR2778337B1 (en) 1998-05-05 2001-08-31 Inst Nat Sante Rech Med ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS
FR2785284B1 (en) 1998-11-02 2000-12-01 Galderma Res & Dev VITAMIN D ANALOGS
AU778767C (en) 1999-05-18 2006-09-07 Theracos, Inc. Novel diphenylethylene compounds
CN1319959C (en) 1999-12-06 2007-06-06 天济药业(深圳)有限公司 Polyhydroxystilbenes and stibene oxides as antisoriatic agents and protein kinase inhibitors
US20020058708A1 (en) 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6541522B2 (en) 2000-08-16 2003-04-01 Insmed Incorporated Methods of using compositions containing hypotriglyceridemically active stilbenoids
US6410596B1 (en) 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids

Also Published As

Publication number Publication date
US20020058701A1 (en) 2002-05-16
WO2002014252A3 (en) 2002-09-12
WO2002014252A2 (en) 2002-02-21
US6552085B2 (en) 2003-04-22

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