AU2001283222A1 - Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1) - Google Patents

Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1)

Info

Publication number
AU2001283222A1
AU2001283222A1 AU2001283222A AU8322201A AU2001283222A1 AU 2001283222 A1 AU2001283222 A1 AU 2001283222A1 AU 2001283222 A AU2001283222 A AU 2001283222A AU 8322201 A AU8322201 A AU 8322201A AU 2001283222 A1 AU2001283222 A1 AU 2001283222A1
Authority
AU
Australia
Prior art keywords
clca
inhibition
reagent
chloride channel
calcium activated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283222A
Inventor
David Ayers
Andrew Grupe
Timothy Mckenzie
James Mcswiggen
David E. Szymkowski
James Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirna Therapeutics Inc
Syntex USA LLC
Original Assignee
Syntex USA LLC
Ribozyme Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC, Ribozyme Pharmaceuticals Inc filed Critical Syntex USA LLC
Publication of AU2001283222A1 publication Critical patent/AU2001283222A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/121—Hammerhead
AU2001283222A 2000-08-09 2001-08-09 Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1) Abandoned AU2001283222A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22438300P 2000-08-09 2000-08-09
US60/224,383 2000-08-09
PCT/US2001/024970 WO2002011674A2 (en) 2000-08-09 2001-08-09 Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1)

Publications (1)

Publication Number Publication Date
AU2001283222A1 true AU2001283222A1 (en) 2002-02-18

Family

ID=22840434

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283222A Abandoned AU2001283222A1 (en) 2000-08-09 2001-08-09 Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1)

Country Status (2)

Country Link
AU (1) AU2001283222A1 (en)
WO (1) WO2002011674A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1390255A (en) * 1999-11-24 2003-01-08 武田药品工业株式会社 Use of disease-associated gene
MXPA05012728A (en) * 2003-05-28 2006-02-13 Wyeth Corp Soluble clca-1 and antagonists to clca-1.
EP3263115A1 (en) * 2016-06-30 2018-01-03 Technische Hochschule Mittelhessen Invention relating to an agent combating pseudomonas aeruginosa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861288A (en) * 1993-10-18 1999-01-19 Ribozyme Pharmaceuticals, Inc. Catalytic DNA
US6103890A (en) * 1994-05-18 2000-08-15 Ribozyme Pharmaceuticals, Inc. Enzymatic nucleic acids that cleave C-fos
EP1108724B1 (en) * 1996-01-16 2007-09-19 Sirna Therpeutics, Inc. Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
JP2002512794A (en) * 1998-04-29 2002-05-08 リボザイム・ファーマシューティカルズ・インコーポレーテッド Nucleotide triphosphates and their incorporation into ribozymes

Also Published As

Publication number Publication date
WO2002011674A3 (en) 2003-09-25
WO2002011674A2 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
AUPS338102A0 (en) Processes for the treatment of a waste material having a high ph and/or alkalinity
AU2001279291A1 (en) Method of treating industrial waste waters
AUPR283801A0 (en) Chemical compounds and methods
AU2001251414A1 (en) Method of detecting carcinomas
AU2001286983A1 (en) Method of treatment
AU2001277534A1 (en) Method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity
AU2001259817A1 (en) Methods of and compounds for inhibiting calpains
HK1057499A1 (en) Method for locating compounds which are suitable for the treatment and/or prophylaxis of obesity
AU2002350319A1 (en) Method and system for the treatment of wastewater
AU2001261676A1 (en) Method and reagent for the inhibition of erg
AU5261701A (en) Method for purification of tetrafluoromethane and use thereof
AU2002243660A1 (en) Method of activation of chemically pure and potable water
AU2001294258A1 (en) Method of purifying plavastatin
AU2002214189A1 (en) Methods of identifying inhibitory compounds and uses thereof
AU2001283222A1 (en) Method and reagent for the inhibition of calcium activated chloride channel-1 (clca-1)
AUPR211500A0 (en) A method of treating sewage
AU2001262177A1 (en) Method of treatment
AUPR536401A0 (en) Method for treatment of waste water
AU2002211674A1 (en) Processes and systems for treating wastewater
AU2001286489A1 (en) Process for the purification of iosoctane and/or diisobutylene
AU4582500A (en) Method, apparatus and use of chelating agents for the purification of calcium sulphate
AU2002353131A1 (en) Detoxification of water containing onium compounds
AU2001242918A1 (en) An apparatus for tapping of water or the like
AU2002340995A1 (en) Method for treating materials containing free or chemically boundcarbon
AUPP751198A0 (en) Purification of A1-proteinase inhibitor